대한의용생체공학회:학술대회논문집 (Proceedings of the KOSOMBE Conference)
- 대한의용생체공학회 1989년도 춘계학술대회
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- Pages.5-6
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- 1989
폴리에틸렌옥사이드 및 설폰산이 결합되어 혈액적합성이 개선된 개질 폴리우레탄
Enhanced Blood Compatibility of PEO-Grafted and Sulfonated Polyurethanes
-
한동근
(한국과학기술원 고분자화학실)
;
- 정서영 (한국과학기술원 고분자화학실) ;
- 안광덕 (한국과학기술원 고분자화학실) ;
- 김영하 (한국과학기술원 고분자화학실) ;
- 김은영 (한국과학기술원 고분자화학실) ;
- 조한익 (서울의대 임상병리과) ;
- 민병구 (서울의대 의공학과) ;
- 최진욱 (서울의대 의공학과)
-
Han, D.K.
(Polym. Chem. Lab., KAIST)
;
- Jeong, S.Y. (Polym. Chem. Lab., KAIST) ;
- Ahn, K.D. (Polym. Chem. Lab., KAIST) ;
- Kim, Y.H. (Polym. Chem. Lab., KAIST) ;
- Kim, U.Y. (Polym. Chem. Lab., KAIST) ;
- Cho, H.I. (Dept. of Clin. Pathol., KAIST) ;
- Min, B.G. (Dept. of Eng., Coll. of Med., Seoul Nat. Univ.) ;
- Choi, J.W. (Dept. of Eng., Coll. of Med., Seoul Nat. Univ.)
- 발행 : 1989.05.26
초록
Polyurethane surface was chemically modified to have different hydrophilic polyethyleneoxide(PEO)/hydrophobic dodecanediol(DDO) groups and negatively charged sulfonate group to investigate the effect to the antithrombogenicity. The hydrophilicity of the surface was significantly increased after PEO grafting or sulfonation. Lowering in-vitro platelet adhesion led to a prologation in the ex-vivo occlusion time. Especially, the sulfonated PU-PEO surface showed most enhanced blood compatibility due to the synergistic effects of PEO and
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