Proceedings of the Ginseng society Conference (고려인삼학회:학술대회논문집)

The Korean Society of Ginseng (고려인삼학회)
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Effect of Ginsenosides on Liver Cell Proliferation in Relation to Its Clinical Applicability

임상적 적용과 관련된 간세포 증식에 미치는 Ginsenosides의 효과

  • Yamamoto Masahiro (Department of Internal Medicine, Nissei Hospital Nishi-ku) ;
  • Miki Shunji (Department of Internal Medicine, Nissei Hospital Nishi-ku) ;
  • Deguchi Hitoshi (Department of Internal Medicine, Nissei Hospital Nishi-ku) ;
  • Ogawa Toshiyuki (Department of Internal Medicine, Nissei Hospital Nishi-ku) ;
  • Uemiya Masanao (Department of Internal Medicine, Nissei Hospital Nishi-ku) ;
  • Nakama Satoshi (Department of Internal Medicine, Nissei Hospital Nishi-ku) ;
  • Uemura Taizo (Department of Internal Medicine, Nissei Hospital Nishi-ku)
  • Published : 1988.08.01
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Abstract

We have studied the ginsenoside effect on DNA RNA and protein synthesis in bone marrow. Ginseng was found to have a beneficial effect on ${\alpha}-napthyl-isothio-cyanate-induced$ hepatobiliary damage. Stimulatory effects of some ginsenosides were shown for cell proliferation and DNA synthesis in a culture liver cell line. The clinical applicability of ginseng on liver diseases will be discussed in relation to traditional medicine.

골수에서 DNA, RNA 및 단백질에 대한 인삼의 효능을 조사하였던 바 $\alpha$-naphthyl-isothio-cyanate로 유도된 간담즙성 상해에도 좋은 효과가 있을 것으로 사료 되었다. 본 연구결과 몇가지 인삼성분이 배양한 간세포에서 DNA합성과 세포증식에 촉진효과를 나타내었다. 또한 전통적인 치료제와 관련하여 간질환에 대한 인삼의 임상적 효과에 대해서 논의하고자 한다.

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