고려인삼학회:학술대회논문집 (Proceedings of the Ginseng society Conference)
- 고려인삼학회 1984년도 학술대회지
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- Pages.141-144
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- 1984
인삼 추출물이 세포의 산소소모에 미치는 영향
EFFECT OF GINSENG EXTRACT ON OXYGEN CONSUMPTION IN RAT LIVER MITOCHONDRIA
- TSO Wung-Wai (Department of Biochemistry and Chinese Medicinal Material Research Center, The Chinese University of Hong Kong Shatin)
- 발행 : 1984.09.01
초록
인삼이 강장제인 약용식물로 인식됨에 따라 세포에 대한 인삼 추출물의 효과를 연구하기 위해 미생물을 실험재료로 연구한 결과, 인삼이 두 단계로 세포 호흡에 영향을 미치는 것으로 관찰되었으며 (Tso and Fung, Microbios, Lett. 13 :
With microorganism as a single cell model to investigate the cellular effect of total extract of ginseng powder, it was found that ginseng affects cellular respiration biphasically (Tso and Fung, 1980; Tso, 1981). As ginseng is recognized to be a tonic medicinal herb, this finding suggests a possible role of ginseng in altering cellular energy metabolism. Along this line, the same effect on mitochondrial oxygen consumption was studied. It was found that under a controlled pH condition, a significant stimulation of the mitochondrial respiration was observed. This stimulation was ginseng dose-dependent. However, when ginseng was applied at an above threshold concentration, an inhibitory effect was noted. This confirms the previous observation with single cell organism and suggests a universal regulation of energy metabolism effect that transcends cell origin.
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