• Title, Summary, Keyword: systematic review

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Systematic Review on Herbal Treatment for Obesity in Adults (성인비만의 한약치료 임상연구에 대한 체계적 고찰)

  • Han, Kyungsun;Lee, Myeong-Jong;Kim, Hojun
    • Journal of Korean Medicine Rehabilitation
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    • v.26 no.4
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    • pp.23-35
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    • 2016
  • Objectives This systematic review is to support the effectiveness of herbal medicine for the treatment of simple obesity in adults. Methods A total of 8 electronic databases were searched in English, Chinese and Korean. Standard methodologies for the systematic review were used to search, analyze and synthesize data based on NECA's guideline for undertaking systematic review and meta-analyses for intervention. Results After screening 1781 potential articles, we identified 13 randomized controlled trials (RCTs). We conducted a meta-analysis for the study using Bangpungtongsung-san and Taeeumjowi-tang to evaluate the effectiveness of herbal medicines on weight loss compared to placebo control. Both herbs showed positive effect in weight, body mass index and waist circumference. In an analysis comparing herbal effects considering constitutions showed that proper treatment can lower adverse events. Conclusions Our results provide evidence that herbal medicine can be an effective treatment for the obesity compare to placebo or to conventional medicine without serious adverse events. Further study is needed to evaluate effectiveness of herbal medicines considering personalized treatment and its safety.

Systematic Review of Fumigation Therapy for Atrophic Vaginitis (위축성 질염의 좌훈 치료 연구에 관한 체계적 문헌 고찰)

  • Baek, Seon-Eun;Jang, Sae-Byul;Choi, Kyung-Hee;Yoo, Jeong-Eun
    • The Journal of Korean Obstetrics and Gynecology
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    • v.29 no.1
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    • pp.92-101
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    • 2016
  • Objectives: The purpose of this systematic review was to overview and evaluate the effectiveness of fumigation treatment for women with atrophic vaginitis. Methods: We searched articles from Pubmed, Chinese Academic Journals (CAJ) and Oasis online databases. Searching keywords were ‘fumigation’, ‘atrophic vaginitis’, ‘vaginitis’, ‘阴道炎’, ‘膣炎’, ‘老年性 阴道炎’, ‘坐熏’, ‘熏洗’, ‘熏浴’, ‘좌훈요법’, ‘질염’, ‘위축성질염’. After searching the articles, we performed quality assessment using Cochrane risk of bias (RoB) tool. Results: Among the 142 articles were searched, 5 randomized controlled clinical trials (RCTs) were finally selected. All of 5 studies showed that fumigation treatment has significant effect on atrophic vaginitis in terms of the effectiveness rate, but 3 studies were not statistically significant. Conclusions: Our systematic review found encouraging but limited evidence of fumigation therapy for atrophic vaginitis. We recommend clinical trials which obtain stronger evidence without the demerits of trial design.

A Study on the Application of Systematic Literature Review for Post-Market Clinical Evaluation of Medical Devices: Focused on the Ophthalmic Electrosurgical system (시판 후 의료기기 임상평가를 위한 체계적 문헌고찰 활용 방안 연구: 안과용전기수술기 사례를 중심으로)

  • Kim, Byung Gwan;Choi, Young Sook;Kim, Mi Sun;Yang, Seok-Jo
    • Journal of Biomedical Engineering Research
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    • v.41 no.1
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    • pp.35-41
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    • 2020
  • In this study, we examined whether the systematic literature review method used in the field of evidence-based medicine could be used for post-market clinical evaluation of medical devices by modifying them to fit the regulatory perspective of medical devices in Korea. For this purpose, systematic literature review was modified and applied to conduct a clinical literature survey on the ophthalmic electrosurgical system(Trabectome®, NeoMediX Corp) used for the treatment of glaucoma. A total of six documents were finally selected, and clinical safety and efficacy information on the indications of the ophthalmic electrosurgical system were effectively presented. In addition, general safety information and unexpected safety information could be distinguished through comparison with medical device adverse event reporting cases. The method used in this study is expected to be used in various ways throughout post-market medical device safety management system and for the purpose of regulation improvement, especially in the field of ophthalmic electrosurgical system.

A systematic review of domestic oral health care programs for elementary school children (초등학생 대상의 국내 구강건강관리 프로그램에 대한 체계적 문헌고찰)

  • Yeo, An-Na;Lee, Su-Young
    • Journal of Korean society of Dental Hygiene
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    • v.20 no.3
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    • pp.257-268
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    • 2020
  • Objectives: This purpose of this study was to examine the trends in interventional research and analyze the contents and results of intervention through a systematic literature review of the domestic research literature, suggesting the effect of an oral care program on elementary school students. Methods: A total of 262 articles were retrieved initially, and the duplicate articles were then removed, excluded after screening titles, abstracts, and full-text articles. Finally, a total of 16 papers were used in the review. Results: The study included 9 articles with the nonequivalent control group pretest-posttest design and 7 with the one-group pretest-posttest design. All articles were of non-randomized studies. The most common index of the interventional effect was dental plaque. Further, oral health behaviors and knowledge, perception, self-efficacy, and DMFT index were common indices. In the quality assessment, in the "blinding of outcome assessment" among six items of ROBANS, 12 studies showed a high risk of bias. Conclusions: In order to develop an interventional oral health care program for elementary school students and evaluate the effectiveness, a strict research design and qualitative improvement of research reports are required, and continuous research should be conducted to develop a systematic protocol.

Effect of warming local anesthesia solutions before intraoral administration in dentistry: a systematic review

  • Tirupathi, Sunny Priyatham;Rajasekhar, Srinitya
    • Journal of Dental Anesthesia and Pain Medicine
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    • v.20 no.4
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    • pp.187-194
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    • 2020
  • Background: The aim of the present systematic review was to evaluate and compare the efficacy of warmed and unwarmed local anesthesia solutions in reduction of pain during intraoral injection administration. Methods: PubMed, Ovid SP, and Cochrane Central Register of Controlled Trials were searched from publication years 1990 to 2020 with relevant MeSH terms. Studies were screened by titles and abstracts, followed by full-texts evaluation of the included studies. Results: A total of four studies were included in the systematic review. Outcomes evaluated were subjective and objective pain during administration of the warmed local anesthesia solution in comparison with the unwarmed local anesthesia solution. Among the four studies that evaluated the self-reported pain score, three studies showed significantly lower pain scores associated with warmed local anesthesia. Only two studies evaluated the observed pain score, and both of them reported a significantly lower pain reaction with the warmed local anesthesia solution. Conclusion: Within the limits of this systematic review, warming the local anesthesia solution to body temperature (37℃) before administration seemed to reduce the discomfort during intraoral local anaesthesia administration, and more high-quality studies should be carried out to validate the same.

A study on systematic review of unplugged activity (언플러그드 활동의 체계적 문헌고찰에 관한 연구)

  • Kim, Jeongrang
    • Journal of The Korean Association of Information Education
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    • v.22 no.1
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    • pp.103-111
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    • 2018
  • In order to examine the educational effects and future directions of unplugged activities, we conducted a systematic review of Korean journals and theses from 2007 to 2016. Three kinds of database were used for systematic review: RISS, KISS, and E-article, and were performed searches using options such as 'unplugged' and 'play-centered'. Based on the protocol selected in the framework of the systematic review, 37 articles were selected analyzed in terms of research status, research subjects, research methods, research hubs, study mechanisms, educational methods, and research effects. Unplugged activities were the most popular among elementary school students. Educational effects were found to have significant effects on academic achievement, problem solving ability, and logical thinking ability. In the affirmative domain, there was a significant effect on interest, curiosity, and motivation. Based on the results of the analysis, the characteristics and implications of Unplugged activities and present the direction of future education were discussed.

Systematic Review of Smoking Prevention Programs for Korean School-aged Children and Adolescents (국내 학령기 아동 및 청소년 흡연예방 프로그램에 대한 체계적 문헌고찰)

  • Lee, Hyejin;Kim, Hyekyeong
    • The Journal of Korean Society for School & Community Health Education
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    • v.18 no.2
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    • pp.27-42
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    • 2017
  • Objectives: The purpose of this study was to investigate the characteristics of smoking prevention programs and their effectiveness for Korean school-aged children and adolescents by using systematic review and meta-analysis. Methods: Electronic searches were performed in RISS, NAL, DBPia, KISS using keywords according to inclusion criteria. 21 studies published from 2003 to the first half of 2017 that dealt with effects of smoking prevention programs for school-aged children and adolescents were selected for systematic review. Results: All 21 studies were quasi-experimental research designs. More than half of the programs(66.7%) were conducted for male and female. Most of the programs were conducted more than once a week(71.4%). 14 studies(66.7%) did not report using a theoretical model. Five dependent variables(knowledge of smoking, attitude toward smoking, non-smoking intention, self-assertiveness, and self-efficacy) were selected to measure the effectiveness of the smoking prevention programs. Knowledge of smoking was the most effective at hedge's g=0.673. Self-efficacy and self-assertiveness variables were statistically significant at hedge's g=0.461 and hedge's g=0.279, respectively. Effect sizes of attitude toward smoking and non-smoking intention were not statistically significant compared to the control group. As a result of the moderator effect analysis on the knowledge of smoking variable, the statistically significant variables were 'gender of participants'(p<0.01) and 'duration of the program'(p<0.001). Conclusions: The results of this study using systematic review and meta-analysis will be evidence-based data for researchers conducting smoking prevention programs in school-aged children and adolescents.

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Frequency, Expected Effects, Obstacles, and Facilitators of Disclosure of Patient Safety Incidents: A Systematic Review

  • Ock, Minsu;Lim, So Yun;Jo, Min-Woo;Lee, Sang-il
    • Journal of Preventive Medicine and Public Health
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    • v.50 no.2
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    • pp.68-82
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    • 2017
  • Objectives: We performed a systematic review to assess and aggregate the available evidence on the frequency, expected effects, obstacles, and facilitators of disclosure of patient safety incidents (DPSI). Methods: We used the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines for this systematic review and searched PubMed, Scopus, and the Cochrane Library for English articles published between 1990 and 2014. Two authors independently conducted the title screening and abstract review. Ninety-nine articles were selected for full-text reviews. One author extracted the data and another verified them. Results: There was considerable variation in the reported frequency of DPSI among medical professionals. The main expected effects of DPSI were decreased intention of the general public to file medical lawsuits and punish medical professionals, increased credibility of medical professionals, increased intention of patients to revisit and recommend physicians or hospitals, higher ratings of quality of care, and alleviation of feelings of guilt among medical professionals. The obstacles to DPSI were fear of medical lawsuits and punishment, fear of a damaged professional reputation among colleagues and patients, diminished patient trust, the complexity of the situation, and the absence of a patient safety culture. However, the factors facilitating DPSI included the creation of a safe environment for reporting patient safety incidents, as well as guidelines and education for DPSI. Conclusions: The reported frequency of the experience of the general public with DPSI was somewhat lower than the reported frequency of DPSI among medical professionals. Although we identified various expected effects of DPSI, more empirical evidence from real cases is required.

Chuna Manual Therapy for Adhesive Capsulitis : A Systematic Review and Meta Analysis (유착성 관절낭염에 대한 추나요법의 효과: 체계적 문헌고찰과 메타분석)

  • Cho, Ju-Chan;Heo, In;Park, Sun-Young;Shin, Byung-Cheul
    • The Journal of Korea CHUNA Manual Medicine for Spine and Nerves
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    • v.14 no.2
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    • pp.1-14
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    • 2019
  • Objectives : To evaluate the effectiveness of Chuna Manual Therapy for adhesive capsulitis by a systematic review manner. Methods : Five foreign electronic databases (Pubmed, Ovid-medline, Embase, Cochrane library, Chinese Academic Journals (CAJ)) and two Korean medical electronic databases (Oriental Medicine Advanced Searching Integrated System (OASIS) and Research Information Sharing Service (RISS)) were searched to find all randomized controlled trials (RCTs) using Chuna Manual Therapy as a treatment for adhesive capsulitis. The methodological quality of each RCT was assessed using the Cochrane risk of bias tool. Results : Twenty-one RCTs met our inclusion criteria. The meta-analysis showed positive results on the use of Chuna Manual Therapy combined with acupuncture or exercise therapy in terms of the efficacy rate and pain using the Visual Analogue Scale (VAS), compared to acupuncture or exercise alone [SMD-1.81 (95% CI & -2.54, -1.08), P<0.001, RR 1.19 (95% CI 1.14, 1.23), P<0.001)]. Positive results in terms of efficacy rate were also obtained comparing Chuna Manual Therapy to acupuncture alone [RR 1.10 (95% CI 1.02, 1.18), P=0.01]. Conclusions : Our systematic review found favorable results on the effectiveness of Chuna Manual Therapy for pain and efficacy rate of adhesive capsulitis. However, evidence was limited due to the lack of well-designed RCTs. More qualified clinical trials are needed to obtain stronger evidence.

Effect of Acupuncture on Sciatica in Rat Models: Systematic Review and Meta-analysis (좌골신경통 백서모델에서 침치료의 효과: 체계적 문헌고찰 및 메타분석)

  • Yoon, Ye-Ji;Kim, Soojeon;Cho, Jae-Heung;Kim, Koh-Woon;Song, Mi-Yeon
    • Journal of Korean Medicine Rehabilitation
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    • v.30 no.1
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    • pp.79-93
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    • 2020
  • Objectives While sciatic neuropathy is one of the common symptoms which have the lifetime incidence of 13~40%, still there is no consensus about the standardized and the most effective conservative treatment. In addition, the importance of systematic review and meta-analysis of preclinical are growing as they could suggest possible effective treatment strategy for future studies. Therefore, we conducted systematic review and meta-analysis to estimate analgesic effect of acupuncture on sciatica in rat models. Methods Systematic search was conducted for all controlled comparative preclinical trials which assessed analgesic effect of acupuncture in sciatica rat models. Database of PubMed, EMBASE, Web of Science, CNKI and 6 Korean databases were used. The primary outcome was pain, which is evaluated by stimulus behavior tests in rat models. We assessed the methodological quality with Systematic Review Centre for Laboratory Animal Experimentation's risk of bias tool. RevMan 5.3 was used for meta-analysis and subgroup analysis was conducted according to treatment site, acupuncture point, treatment period and frequency used in electroacupuncture. Results 14 studies were finally included following our inclusion criteria. The data from meta-analysis indicated that the acupuncture significantly improved the result values of behavior tests for pain evaluation, compared to no-treatment control group in animal models (standardized mean difference=4.43, 95% confidence interval 3.16 to 5.69, Z=6.84, p<0.00001; χ2=68.02, p<0.00001; I2=82%). The results of subgroup analysis indicate that acupuncture treatment of unilateral site, distal acupoints, longer treatment period and applying 2/100 Hz frequency in electroacupuncture could be more effective. Conclusions Systematic review and meta-analysis of animal studies are getting important for the future clinical studies and the improvement of heatlh care. Therefore the results of the study would provide evidence and better design for the forthcoming studies.