• Title, Summary, Keyword: progression

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Exploring the Progression of Meta-Modeling Knowledge (MMK) and Relationship between MMK Progression Level and Actual Practice for Science Gifted (과학영재 학생들의 메타모델링 지식(MMK) 발달 및 MMK 발달수준과 실제 수행과의 관계 탐색)

  • Kim, Jung-Eun;Kim, Sungki;Paik, Seoung-Hey
    • Journal of the Korean Chemical Society
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    • v.64 no.2
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    • pp.111-118
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    • 2020
  • The purpose of this study is to explore the progression of MMK and the relationship between MMK progression level and actual practice. First, the Rasch model was used to measure MMK progression level of 51 students twice during the interval of one year. Thereafter, chi-squared test was used to determine whether there was a significant change in MMK progression. As a result of chi-squared test, there was no statistically significant change in MMK progression (p>.05). Secondly, we analyzed the relationship between MMK progression level and practice for 7 gifted students. As a result of the analysis, it was confirmed that the student's response in practice can not exceed MMK progression level. There were also cases where students have high MMK progression level showed low response in practice. The results of these two studies show that gifted education programs are needed to increase MMK progression and to provide gifted education that can connect knowledge and practice.

On the Definition of Geometrical Progression of the High school (등비수열의 정의에 대한 연구)

  • Lee, Min-Jung;Lee, Yang
    • The Mathematical Education
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    • v.51 no.3
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    • pp.211-221
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    • 2012
  • We discovered that definition of a Geometrical Progression(Sequence) have some differences in domestic textbooks & some foreign countries' books. This will be able to cause a chaos when students divide whether a sequence is a Geometrical Progression(Sequence) or not, and a question error when teachers compose questions about convergence conditions of Infinite Geometric progressions & series. We took a question investigation for students about definition of a Geometrical Progression(that is called G. P.), we discovered that high level students have an error about definition of a G. P.. So We modified expressions of terminology in domestic textbooks appropriately through a Geometrical Progression(Sequence), infinite series, & infinite geometrical series in some foreign countries' books.

Role of G Protein-Coupled Estrogen Receptor in Cancer Progression

  • Jung, Joohee
    • Toxicological Research
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    • v.35 no.3
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    • pp.209-214
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    • 2019
  • Cancer is the leading cause of mortality worldwide. In cancer progression, sex hormones and their receptors are thought to be major factors. Many studies have reported the effects of estrogen and estrogen receptors (ERs) in cancer development and progression. Among them, G protein-coupled estrogen receptor (GPER), a G protein-coupled receptor, has been identified as an estrogen membrane receptor unrelated to nuclear ER. The mechanism of GPER, including its biological action, function, and role, has been studied in various cancer types. In this review, we discuss the relation between GPER and estrogen or estrogen agonists/antagonists and cancer progression.

Oriental Medicine Music therapy for The treatment of Sasangin's disdases (사상체질인(四象體質人)의 병증(病證) 치료를 위한 한방음악치료(韓方音樂治療)에 관한 연구;장부대소(臟腑大小)와 호흡출납(呼吸出納)을 중심으로)

  • Lee, Seung-Hyun
    • Journal of Korean Medical classics
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    • v.20 no.4
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    • pp.119-126
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    • 2007
  • The biological and pathological states of lung, spleen, liver and kidneys are determined by nature and emotion of sorrow, anger, joy and pleasure, It is considered that the music, besides medicine or acupuncture, can be a way of treating as a therapeutics for the treatment of Sasangin's diseases. This study is to find out a way of music therapy for the treatment of Sasangin's diseases. The ways of music therapy in each constitution based on 'the great and small of Viscera and Bowels' and 'the exhale and inhale, the drawing in and sending out' are as follows: 1. In case of Soeumin, a skip going up melodic progression, dotted rhythm and the major triad harmonic progression are recommended to improve the Qi of warm Yang. 2. In case of Soyangin, in regular sequence down melodic progression, a sixteenth note and the minor triad harmonic progression are recommended to improve the Qi of cool Yin. 3. In case of Taeumin, in regular sequence going up melodic progression, a sixteenth note and the bright and active the major triad harmonic progression are recommended to improve the Qi of dispersing exhale. 4. In case of Taeyangin, a skip down melodic progression, a quarter note and a diminished triad harmonic progression are recommended to improve the Qi of gathering inhale.

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The Use of MR Perfusion Imaging in the Evaluation of Tumor Progression in Gliomas

  • Snelling, Brian;Shah, Ashish H.;Buttrick, Simon;Benveniste, Ronald
    • Journal of Korean Neurosurgical Society
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    • v.60 no.1
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    • pp.15-20
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    • 2017
  • Objective : Diagnosing tumor progression and pseudoprogression remains challenging for many clinicians. Accurate recognition of these findings remains paramount given necessity of prompt treatment. However, no consensus has been reached on the optimal technique to discriminate tumor progression. We sought to investigate the role of magnetic resonance perfusion (MRP) to evaluate tumor progression in glioma patients. Methods : An institutional retrospective review of glioma patients undergoing MRP with concurrent clinical follow up visit was performed. MRP was evaluated in its ability to predict tumor progression, defined clinically or radiographically, at concurrent clinical visit and at follow up visit. The data was then analyzed based on glioma grade and subtype. Resusts : A total of 337 scans and associated clinical visits were reviewed from 64 patients. Sensitivity, specificity, positive and negative predictive value were reported for each tumor subtype and grade. The sensitivity and specificity for high-grade glioma were 60.8% and 87.8% respectively, compared to low-grade glioma which were 85.7% and 89.0% respectively. The value of MRP to assess future tumor progression within 90 days was 46.9% (sensitivity) and 85.0% (specificity). Conclusion : Based on our retrospective review, we concluded that adjunct imaging modalities such as MRP are necessary to help diagnose clinical disease progression. However, there is no clear role for stand-alone surveillance MRP imaging in glioma patients especially to predict future tumor progression. It is best used as an adjunctive measure in patients in whom progression is suspected either clinically or radiographically.

Stereotactic body radiation therapy for liver oligo-recurrence and oligo-progression from various tumors

  • Cha, Yu Jin;Kim, Mi-Sook;Jang, Won-Il;Seo, Young Seok;Cho, Chul Koo;Yoo, Hyung Jun;Paik, Eun Kyung
    • Radiation Oncology Journal
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    • v.35 no.2
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    • pp.172-179
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    • 2017
  • Purpose: To evaluate the outcomes of stereotactic body radiation therapy (SBRT) for patients with liver oligo-recurrence and oligo-progression from various primary tumors. Materials and Methods: Between 2002 and 2013, 72 patients with liver oligo-recurrence (oligo-metastasis with a controlled primary tumor) and oligo-progression (contradictory progression of a few sites of disease despite an overall tumor burden response to therapy) underwent SBRT. Of these, 9 and 8 patients with uncontrollable distant metastases and patients immediate loss to follow-up, respectively, were excluded. The total planning target volume was used to select the SBRT dose (median, 48 Gy; range, 30 to 60 Gy, 3-4 fractions). Toxicity was evaluated using the Common Toxicity Criteria for Adverse Events v4.0. Results: We evaluated 55 patients (77 lesions) treated with SBRT for liver metastases. All patients had controlled primary lesions, and 28 patients had stable lesions at another site (oligo-progression). The most common primary site was the colon (36 patients), followed by the stomach (6 patients) and other sites (13 patients). The 2-year local control and progression-free survival rates were 68% and 22%, respectively. The 2- and 5-year overall survival rates were 56% and 20%, respectively. The most common adverse events were grade 1-2 fatigue, nausea, and vomiting; no grade ${\geq}3$ toxicities were observed. Univariate analysis revealed that oligo-progression associated with poor survival. Conclusion: SBRT for liver oligo-recurrence and oligo-progression appears safe, with similar local control rates. For liver oligo-progression, criteria are needed to select patients in whom improved overall survival can be expected through SBRT.

Correlation between Gait Speed and Velocity of Center of Pressure Progression during Stance Phase in the Older Adults with Cognitive Decline: A Pilot Study

  • Seon, Hee-Chang;Lee, Han-Suk;Ko, Man-Soo;Park, Sun-Wook
    • Journal of the Korean Society of Physical Medicine
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    • v.15 no.4
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    • pp.67-74
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    • 2020
  • PURPOSE: The progression of the center of pressure (COP) velocity of the stance phase may have important roles for predicting gait speed in older adults with cognitive decline. This study was conducted to identify the correlation between gait speed and the velocity of COP progression during the stance phase in older adults with cognitive decline. METHODS: Forty adults aged 65 years or older (twenty participants without cognitive decline, 20 participants with cognitive decline) were recruited. The COP progression velocity was measured using an F-scan pressure-sensitive insole system. The stance phase was divided into four sub-stages. (loading response, mid-stance, terminal stance, and pre-swing). Gait speed, double support phase, and cadence were also measured. Correlations and multiple regression analyses were performed. RESULTS: Gait speed was associated with the COP progression velocity in midstance (r = .719, p < .05), cadence (r = .719, p < .05) and the COP progression velocity in loading response velocity (r = .515, p < .05) in older adults with cognitive decline. However, no correlation was found in older adults without cognitive decline. In multiple regression analysis using gait speed as a dependent variable, the COP progression velocity in midstance and cadence were significant predictors of gait speed, with the COP progression velocity being the most significant predictor. CONCLUSION: The COP progression velocity is an important factor for predicting gait speed in older adults with cognitive decline, suggesting that the cognitive function influences gait speed and the velocity of COP progression.

The reasonable timing of the adjuvant radiotherapy in the treatment of uterine carcinosarcoma according to the surgical intent: suggestion based on progression patterns

  • Yu, Jeong Il;Choi, Doo Ho;Huh, Seung Jae;Park, Won;Oh, Dongryul;Bae, Duk Soo
    • Radiation Oncology Journal
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    • v.31 no.2
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    • pp.72-80
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    • 2013
  • Purpose: We designed this study to identify and suggest the reasonable timing of adjuvant radiotherapy in the treatment of uterine carcinosarcoma according to the surgical intent and patterns of progression. Materials and Methods: We retrospectively analyzed a total of 50 carcinosarcoma patients diagnosed between 1995 and 2010. Among these 50 patients, 32 underwent curative surgery and 13 underwent maximal tumor debulking surgery. The remaining five patients underwent biopsy only. Twenty-six patients received chemotherapy, and 15 patients received adjuvant radiotherapy. Results: The median follow-up period was 17.3 months. Curative resection (p < 0.001) and stage (p < 0.001) were statistically significant factors affecting survival. During follow-up, 30 patients showed progression. Among these, eight patients (16.0%) had loco-regional progression only. The patients who had received adjuvant radiotherapy did not show loco-regional progression, and radiotherapy was a significant negative risk factor for loco-regional progression (p = 0.01). The time to loco-regional progression was much earlier for non-curative than curative resection (range, 0.7 to 7.6 months vs. 7.5 to 39.0 months). Conclusion: Adjuvant radiotherapy in the treatment of carcinosarcoma might be related to a low loco-regional progression rate. Radiotherapy should be considered in non-curatively resected patients as soon as possible.

A Framework for Progression in the Professional Development and Learning of Secondary Science Teachers' Teaching Practice (중등 과학교사의 수업 실행 전문성의 발달과 학습 틀)

  • Choi, Young;Lee, Musang;Song, Myungseub
    • Journal of Science Education
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    • v.34 no.1
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    • pp.124-139
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    • 2010
  • The purpose of this study was to develop and apply a framework for progression in the professional development and learning of secondary science teachers' teaching practice. The progression in the professional development was modified Pilhee Woo's framework(2010), and in the learning was developed by the researchers. The former included 6 elements and 36 aspects. The progression of each aspect was composed of five level criteria. The content validity is 96.4% and the reliability is .96. The latter was composed of another five level criteria. The content validity is 96.0% and the reliability is .95. Internet-online test and the questionnaire were administered to 203 secondary science teachers who were selected by convenience sampling. The mean level of the progression in the professional development and learning were 2.21 and 2.95. ANOVA, t-test and correlation analysis were conducted to compare differences by the characteristics of teachers. The level of the progression in the professional development and learning was significant difference according to almost all of teachers' characteristics. The level of the progression in the professional development was significantly correlated with the level of the progression in the learning.

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Red Cell Distribution Width as a Predictor of Prostate Cancer Progression

  • Albayrak, Sebahattin;Zengin, Kursad;Tanik, Serhat;Bakirtas, Hasan;Imamoglu, Abdurrahim;Gurdal, Mesut
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.18
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    • pp.7781-7784
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    • 2014
  • Background: The aims of this study were to investigate the utility of red blood cell distribution width (RDW) as a simple and readily available marker in prostate cancer, as well as to evaluate RDW as a predictor of progression in prostate cancer patients. Materials and Methods: We evaluated 62 newly diagnosed prostate cancer patients who underwent transrectal ultrasound (TRUS)-guided biopsy and 62 healthy controls of mean age 64 (range, 45-75) years at the Urology Clinic of Bozok University Hospital. Data collection was performed using our laboratory information system database to retrieve findings regarding RDW, hemoglobin, prostatespecific antigen (PSA), and age. The RDW values were compared between the healthy control group and prostate cancer patients. A high risk of progression as defined as a Gleason score (GS) >6, total number of cores positive for cancer >33%, each core containing >50% cancer cells, and a prostate-specific antigen (PSA) level >10 ng/mL. Patients were classified according to risk of progression, as well as divided into subgroups according to the RDW quartile. Results: The mean RDW value of prostate cancer patients was 14.6, compared with 13.7 in the healthy control group (p=0.001). A higher RDW was associated with an increased risk of progression, whereas a lower RDW value was correlated with a low risk of progression. Conclusions: RDW is an easily derived measure that might, in combination with other markers, help predict prostate cancer risk and progression. We suggest that RDW may be used in combination with other parameters in the assessment of prostate cancer.