• Title, Summary, Keyword: pectin

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The Effect of Dietary Fiber on The Liver Xanthine Oxidase Activity in Rats (식이섬유 첨가가 흰쥐의 간 Xanthine Oxidase 활성에 미치는 영향)

  • 윤종국;이영순;이혜자
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.24 no.6
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    • pp.843-847
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    • 1995
  • To evaluate the effect of dietary fiber on the protein utilization, Sprague-Dawley rats were fed diet containing 15% or 30% of pectin and 15% or 30% ${\alpha}-cellulose$. Control group was fed fiber free diet. The animals were fed and libitum for 5 weeks. Weight gain was less in the rat fed a pectin supplemented diet than those fed ${\alpha}-cellulose$ supplemented or control diet. Furthermore, weight gain decreased more by the addition of 30% pectin than 15% pectin level. The rats fed ${\alpha}-cellulose$ or pectin shwoed a decreasing tendency of food efficiency ratio compared to the control group. The rats fed a diet containing pectin showed an increasing tendency of the liver weight compared to the control group and those fed cellulose. The rats fed a diet containing pectin showed a decreasing tendency of hepatic protein content compared to those fed cellulose or control group fed fiber free diet. The rats fed diet containing pectin(15%, 30%) showed remarkable decreased activity of liver xanthine oxidase compared with those fed ${\alpha}-cellulose$ or the control group. These results suggested that the pectin may be alter the absorption of protein in intestinal lumen.

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Anti-Oxidative Activity of Pectin and Its Stabilizing Effect on Retinyl Palmitate

  • Ro, Jieun;Kim, Yeongseok;Kim, Hyeongmin;Jang, Soung Baek;Lee, Hyun Joo;Chakma, Suharto;Jeong, Ji Hoon;Lee, Jaehwi
    • The Korean Journal of Physiology and Pharmacology
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    • v.17 no.3
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    • pp.197-201
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    • 2013
  • The purpose of this study was to examine the anti-oxidative activity of pectin and other polysaccharides in order to develop a cosmeceutical base having anti-oxidative effects towards retinyl palmitate (RP). The anti-oxidative stabilizing effects of pectin and other polysaccharides on RP were evaluated by DPPH assay and then the stabilizing effect of pectin on RP was examined as a function of time. Among the polysaccharides we examined, pectin exhibited a considerably higher anti-oxidative activity, with an approximately 5-fold greater DPPH radical scavenging effect compared to other polysaccharides. The DPPH radical scavenging effect of pectin increased gradually with increasing concentrations of pectin. At two different RP concentrations, 0.01 and 0.1% in ethanol, addition of pectin improved the stability of RP in a concentration dependent manner. The stabilizing effect of pectin on RP was more effective for the lower concentration of RP (0.01%, v/v). Further, degradation of RP was reduced following the addition of pectin as measured over 8 hours. From the results obtained, it can be suggested that pectin may be a promising ingredient for cosmeceutical bases designed to stabilize RP or other pharmacological agents subject to degradation by oxidation.

Effects of Dietary Pectin, Tangerine Pulp Meal, Propionate, Lactate or Fumarate on Serum and Liver Cholesterol Levels, and Dietary Pectin on Cholesterol Absorption in Bats

  • Yang, Yong-Ho;Park, Hak-Moon;Kim, Kyu-Il
    • Journal of Nutrition and Health
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    • v.31 no.5
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    • pp.914-920
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    • 1998
  • The effect of dietary pectin, tangerine pulp meal, propionate, lactate or fumarate on cholesterol (C) and triacylglycerol(TG) levels in the serum and liver, and the effect of pectin on dietary C absorption were studied in a series of three experiments. Mature female Sprague Dawley rats were fed a control diet or diets containing 5% pectin, 5% tangerine pulp meal, 3% propionate, 3% lactate 3% fumarate, or 10% pectin. Serum total C levels were lower(p<0.05) in rats fed the diet containing 5% pectin than in control rats after a 4-week feeding period(93.8 vs 119.2mg/100mL). Serum HDL, LDL+VLDL C levels were not different among diet groups. Liver total C level was also lower(p<0.05) in rats fed the diet containing 5% pectin than in control rats, but liver TG level was not influenced by diet. Dietary propionate, lactate or fumarate did not reduce serum C, indicating that propionate is not a regulator of serum C. However, dietary pectin(10%) increased fecal excretion of dietary C(or its metabolites) more than 70% over a control value. Our data indicate that dietary pectin reduces serum and liver C levels by increased fecal secretion of dietary C, but not by its fermentation product propionate or other gluconeogenic substrates. (Korean J Nutrition 31(5) : 914∼920, 1998)

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Prediction of Firmness and Strength of Low-ester Pectin Gel from Chemical Composition (Low-ester Pectin Gel의 단단함과 강도(强度)의 예측)

  • Kim, Woo-Jung;Smit, C.J.B.;Rao, V.N.M.
    • Korean Journal of Food Science and Technology
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    • v.18 no.5
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    • pp.364-371
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    • 1986
  • High-ester pectin was demethylated by the treatments of HCl alone and a combination of HCl and $NH_4OH$. The low-ester pectin prepared were analyzed for chemical composition and the pectin gels were evaluated for firmness by sag values and strength by puncture stress. Gels made from HCl demethylated sample showed brittle, weak and poor elastic characteristics while the $HCl-NH_4OH$ treated samples generally resulted in a smooth and elastic gels except those samples having very low content of ester group or acid amide group. Statistical analysis showed that significant correlations were found between sag values and ester content or molecular weight, and puncture stress and ester content, acid amide groups or molecular weight. The equations derived for sag, puncture stress and sag/puncture stress from chemical data could be useful for prediction of some of the physical properties of low-ester pectin gel.

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Chemical and Gelation characteristics of Pectins Obtained from Ripened and Unripened Crabapples (과일 내의 pectin 함량 및 성숙도에 따른 pectin 특성 변화에 관한 연구)

  • 문수재
    • Journal of the Korean Home Economics Association
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    • v.19 no.4
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    • pp.33-39
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    • 1981
  • This study was attempted to determine the pectin contents of various fruits(Cherry, strawberry, plum, peach, apricot, apple, crabapple) and to investigate the changes in the properties of pectin and pectin gel during crabapple ripening. Methoxyl content, molecular weight and intrinsic viscosity were measured in ripened and unripened crabapples. In order to determine the characteristics of pectin gel, percent sag was measured by exchange Ridgelimeter, hardness and textural characteristics of jellies were measured by a penetrometer and a texturometer. The experimental results are summarized as follows: 1. The pectin contents of various fruits were 1.16% for cherry, 3.17% fir strawberry, 4.29% for plum, 5.51% for apricot, and pectin contents of peaches and apples varies depends on varieties from 4.54% to 5.61% to 6.52, respectively. The pectin contents of unripened and ripened crabapple wee 9.21% and 9.84% respectively, indicating that pectin content increased with fruit maturity. 2. The methoxyl contents, which was 6.61%~6.95%, was very low and it increased significantly during fruit ripening. Further, a decrease in acetyl content, intrinsic viscosity, molecular weight occurred during the ripening of crabapples. 3. The percent sag of crabapple jellies increased with fruit maturity from 5.26% to 5.79%, and the corresponding jelly grade decreased in ripened crabapple. 4. The hardness of jellies determined by a penetrometer was 79.15 pp.U. for ripened crabapple jelly, 90.62 pp.U. for unripe ned crabapple jelly. 5. In the textural characteristics of gels measured by a texturometer, the gels made from unripened crabapple were shown to have the highest values in hardness, cohesiveness, adhesiveness and gumminess.

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Changes in the Cell Wall Components of Persimmon Fruits during Maturation and Postharvest (감과실의 성숙과 추숙중의 세포벽 구성성분의 변화)

  • Shin, Seung-Ryeul;Kim, Ju-Nam;Kim, Soon-Dong;Kim, Kwang-Soo
    • Korean Journal of Food Science and Technology
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    • v.22 no.7
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    • pp.738-742
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    • 1990
  • Cell wall components were decreased during maturation and postharvest of persimmon fruits. Contents of pectin and alkali-soluble hemicellulose were increased during maturity, but those of acid-soluble hemicellulose were decreased. Contents of pectin and alkali-soluble hemicellulose were decrease in soft persimmon, whereas acid-soluble hemicellulose was increased remarkably. Cellulose contents were increased during maturation and this tend was notable in soft persimmon. Contents of cell wall polysaccharides per 100g-fresh weight were decreased. Contents of total pectin and insoluble pectin were increased during maturation but decreased in soft persimmon. Content of water-soluble pectin was increased during maturation and postharvest.

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Changes in the Pectic Substance during Maturity of Apple (사과의 성숙에 따른 Pectin질의 변화)

  • Kim, Yeung-Ji;Kim, Chang-Sik
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.17 no.1
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    • pp.63-68
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    • 1988
  • The changes of methoxy content. compositional sugars. degree of esterification (DE) and pectic substances such as LMP (low methoxy pectin), HMP (high methoxy pectin) IAP (ionically associated pectin) and CBP (covalently bounded pectin) of Fuji apple were investigated during maturity. The contents of LMP+HMP and IAP+CBP in alcohol insoluble solid(AIS) were 70% and 20%. respectively. These pectic substances were increased slightly during maturity. The reductions of hexose and uronic acid were Iron 20-50% and from 2-4%, respectively, but the inclosed of pentose was from 1-9% in LMP, HMP, IAP and CBP during maturity of Fuji apple. The galactose was decreased significantly among hexose. Whereas the relative ratio of uronic acid in HMP and CBP was increased.

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Pectin Microspheres for Oral Colon Delivery: Preparation Using Spray Drying Method and In Vitro Release of Release of Indomethacin

  • Lee, Chang-Moon;Kim, Dong-Woon;Lee, Hyun-Chul;Lee, Ki-Young
    • Biotechnology and Bioprocess Engineering:BBE
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    • v.9 no.3
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    • pp.191-195
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    • 2004
  • Drug delivery systems that are based on pectin have been studied for colon specific delivery using the specific activity of colon microflora. The aim of this study was to design a novel method of manufacturing pectin microspheres without oils and surfactants and to investigate the potential use of the pectin microspheres as an oral colon-specific drug carrier. The pectin microspheres were successfully formed using the spray drying method and crosslinking with calcium chloride. From the crosslinked pectin microspheres, indomethacin (IND) release was more suppressed than its release from non-crosslinked microspheres. In a low pH (pH 1.4) environment, the pectin microspheres released IND at an amount of about 18${\pm}$2% of the total loaded weight for 24 h while the release rate of IND was stimulated at neutral pH (pH 7.4). IND release from the pectin microspheres was increased by the addition of pectinase. The results clearly demonstrate that the pectin microspheres that were prepared by the spray drying and crosslinking methods are potential carriers for colon-specific drug deliveries.

The Effect of Pear Pectin on Blood Pressure, Plasma Renin ANP and Cardiac Hypertrophy in Hypertensive Rat Induced by 2K1C (배 추출 펙틴이 2K1C 고혈압 흰쥐의 혈압, 혈장 Renin, ANP 및 Cardiac Hypertrophy 에 미치는 영향)

  • Na, Chang-Su;Yun, Dae-Hwan;Choi, Dong-Hee;Kim, Jeong-Sang;Cao, Chun-Hua;Eun, Jong-Bang
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.32 no.5
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    • pp.700-705
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    • 2003
  • Oriental pear was used as treatment of asthma, control of blood pressure tonic medicine vasoactio, diabetes in oriental medicine. In this study, it was investigated that pear pectin effects on cardiovascular system as blood pressure and renin and atrial natriuretic peptide (ANP) in plasma, cardiac hypertrophy. The experiments were performed on Sprague-Dawley rats, 2K1C hypertension model was prepared by constricting the left renal artery with a sliver clip. Animals were then divided into four groups, 5 mg/kg, 10 mg/kg, 15 mg/kg and the control, pear pectin and apple pectin solutions were supplied with them. The blood pressure was more decreased in pear pectin 10 mg/kg than in apple pectin. The plasma ANP was decreased in pear pectin 10 mg/kg, and renin was increased in same concentration of drug. Cardiac hypertrophy had a tendency to decrease in pear pectin 15 mg/kg, but was not statistically significant compared to control group.

Release Properties of BSA from Pectin Heads for Colonic Drug Delivery (Colonic Delivery를 위한 펙틴 비드로부터 BSA의 방출 특성)

  • 최춘순;박상무;송원현;이창문;이기영;김동운;김진철
    • KSBB Journal
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    • v.18 no.2
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    • pp.161-164
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    • 2003
  • Oral drug delivery system using pectin gel was developed for colon-targeting of peptide drug. BSA(bovine serum albumin)-loaded pectin and pectin-alginate beads were prepared for drug release properties in vitro. Morphological studies by electron microscopy indicated that pectin and pectin-alginate beads were spherical in shape and approximately 1.0 mm. In order to find the suitable beads, effects of cross-linking agents (calcium chloride or zinc acetate) and drying temperature of beads were investigated. Drug release decreased with concentration of cross-linking agents and drying temperature. For colonic drug delivery from pectin and pectin-alginate beads, pectin degradable enzymes were added at 5 hrs from the beginning of drug release. After addition of enzymes, drug release was suddenly increased against free enzymes. Therefore, pectin and pectin-alginate beads can be promised as useful drug release carriers for colon-targeted delivery.