• Title/Summary/Keyword: low density lipoprotein-cholesterol

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Effects of the Dietary Boiled Eggs on the Antithrombotic Activity and Cholesterol Metabolism in Rats (항혈전작용 및 콜레스테롤 대사에 관한 흰쥐 식이내 삶은 계란 급여 효과)

  • 박병성;장애라
    • Food Science of Animal Resources
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    • v.20 no.1
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    • pp.1-7
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    • 2000
  • The influence of the ditary containing boiled eggs on the plasma cholesterol level and antithrombotic activity in rats was studied. Rats were fed basal diet(0% boiled eggs) as a control group or diets containing 25% and 50% boiled eggs or a mixed diet with 95% boiled eggs plus 5% $\alpha$-cellulose powder as a experimental groups for 30 days. The bleeding time and whole blood clotting time were significantly(P<0.05) increased by feeding diet containing 25% boiled eggs compared to groups of basal diet, 50% or 95% boiled eggs diets. The plasma clotting time was high in group of 25% boiled eggs diet. However, there were no difference in plasma clotting time among rats fed the dietary boiled eggs. The levels of plasma total cholesterol(TC) and low density plus very low density lipoprotein cholesterol(LDL, VLDL-C) were significantly(P<0.05) highest in group 95% boiled eggs diet compared to others. There were no differences in high density lipoprotein cholesterol(HDL-C) among rats fed the dietary boiled eggs. The levels of plasma TC, HDL-C, LDL$.$VLDL-C and the ratios of HDL-C/TC were not significant among the basal diet, 25% and 50% boiled eggs diets. These results suggest that the intakes of the dietary boiled eggs have the antithrombotic activity and plasma cholesterol lowering effect.

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Metabolic Syndrome and Life Style in China

  • Wu Pei-Ying;Song Xiao-Min;Jin Qi-Lin;Wang Xin-Qiao;Wang Ai-Rong
    • Journal of Community Nutrition
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    • v.6 no.3
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    • pp.141-145
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    • 2004
  • The purpose of this study was to explore the relationship between life style and metabolic syndrome. The cross-sectional survey was conducted in Pingliang community in Shanghai in Jan 2003. The data was collected by questionnaire, and the results were analyzed by SPSS. It was found that the prevalence of Metabolic Syndrome (MS) was $13.4\%$ in the community, and the body mass index (BMI), waist-to-hip ratio (WHR), systolic blood pressure (SBP), diastolic blood pressure (DBP), serum triglyceride (TG), total cholesterol(TC), low density lipoprotein-cholesterol (LDL-C), and fast plasma glucose (FPG) in MS group were higher than that in non-MS group. Logistic regression analysis indicated that BMI and WHR were positively correlated to the prevalence of MS, and physical activity was negatively correlated to the prevalence of MS. People with higher education levels (${\geq}10y$) had lower BMI, SBP, DBP, LDL-C and FPG. The prevalence of MS in the higher education level group was significantly lower than that of the lower education level group. These results suggested that BMI, WHR and physical activity were important factors of MS, and education background played an important role in the occurrence of MS. Therefore, it is very important to build a healthy life style for preventing and controlling the incidence and developing of MS.

Hypolipidemic Effects of Biopolymers Extracted from Culture Broth, Mycelia, and Fruiting Bodies of Auricularia auricula-judae in Dietary-induced Hyperlipidemic Rats

  • Jeong, Hun;Yang, Byung-Keun;Jeong, Yong-Tae;Kim, Guk-Nam;Jeong, Yu-Sun;Kim, Sang-Min;Mehta, Pradeep;Song, Chi-Hyun
    • Mycobiology
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    • v.35 no.1
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    • pp.16-20
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    • 2007
  • Hypolipidemic effect of biopolymers extracted from culture broth (CP), mycelia (MP), and fruiting bodies (FP) of Auricularia auricula-judae was investigated in dietary-induced hyperlipidemic rats. The experimental animals were administrated (100 mg/kg body weight) with different biopolymers, daily for 4 weeks. Hypolipidemic effects were achieved in all the experimental groups, however, FP was proved to be the most potent one. The administration of the FP reduced the plasma triglyceride, total cholesterol, low-density lipoprotein cholesterol, and atherogenic index by 24.3, 28.5, 36.4, and 40.9%, respectively, while increased the high-density lipoprotein cholesterol level (9.0%), when compared to the saline (control) administered group.

Plasma Concentrations of Lipid Profiles and Lipoprotein(a) In Type 2 Diabetes Mellitus Patients with Macrovascular Complications (제2형 당뇨병 환자의 대혈관 합병증 유무별 혈중 지질농도와 Lipoprotein(a) 비교)

  • Song Min Sun;Yoo Yang Sook;Kim Hee Seung
    • Journal of Korean Public Health Nursing
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    • v.16 no.1
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    • pp.115-122
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    • 2002
  • The purpose of this study to examine lipid profiles and lipoprotein (a) concentrations and identify the risk factors of type 2 diabetes mellitus patients with macrovascular complications. The subjects were consisted of 618 out patients with type 2 diabetes mellitus from beginning of March through the end of April in 2001, who visited at the endocrinology department at Kangnam St. Mary's Hospital of Catholic University in Seoul. The patient's clinical laboratory data and the occurrence of chronic complications of diabetes were assessed at medical record review. The data were analyzed using for t-test. chi-square test and logistic regression. The results were as follows : 1. There were no significant differences in age. duration of diabetes. body mass index, sex, fasting blood glucose, 2-hour postprandial blood glucose and $HbA_{1}c$ level between macrovascular complication group and non macrovascular complication group. 2. There were significant differences in the level of total cholesterol. triglyceride. HDL(High density lipoprotein) cholesterol, LDL(Low density lipoprotein) cholesterol and lipoprotein(a) between macrovascular complication group and non macrovascular complication group. 3. Significant factor associated with macrovascular complication in the logistic regression best gut model was HDL cholesterol.

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Reductive effect of body weight in rats fed a high-fat diet by Sense-line

  • An, Hyo-Jin;Chung, Hwan-Suck;Jeong, Hyun-Ja;Lee, Soon-Ah;Kim, Hyung-Min;Baek, Seung-Hwa
    • Advances in Traditional Medicine
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    • v.3 no.1
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    • pp.29-33
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    • 2003
  • Sense-line (SL), a dietary functional food, is our invention for weight loss. To evaluate such an effect of SL, we analyzed the plasma levels of total cholesterol, low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol, and weight changes after rats were fed on high fat diet with SL for 20 days. Plasma total cholesterol level and LDL-cholesterol level was decreased by 52% and 91.89% in 5% SL treated group and by 13% and 51.45% in 10% SL treated group, respectively. But HDL-cholesterol was not changed. In addition, the weight was significantly lower in SL group than in high-fat diet group (P<0.05). Our findings indicate that SL may contain compounds with actions, which can treat blood circulatory trouble as well as overweight.

Effect of Lactobacillus acidophilus based probiotic product supplementation on the blood profile, fecal noxious gas emission, and fecal shedding of lactic acid bacteria and coliform bacteria in healthy adult Beagle dogs

  • Sun, Hao Yang;Kim, In Ho
    • Korean Journal of Agricultural Science
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    • v.47 no.3
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    • pp.437-443
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    • 2020
  • The aim of this study was to evaluate the effect of Lactobacillus acidophilus probiotic (LAP) product supplementation on the blood profile, fecal noxious gas emission, and fecal shedding of lactic acid bacteria and coliform bacteria in healthy adult Beagle dogs. In total, 14 Beagle dogs with an average initial body weight of 10.19 ± 0.61 kg were randomly assigned into two dietary treatments,with and without LAP supplementation, for a 28-day feeding trial. At the end of the experiment, there was no significant (p > 0.05) difference in the concentration of serum total cholesterol, high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), white blood cell (WBC), red blood cell (RBC), blood lymphocyte percentage, fecal hydrogen sulfide (H2S) and total mercaptans (R.SH) emission, and fecal coliforms counts. However, the serum concentrations of the triglyceride and fecal ammonia (NH3) emission of the LAP treatment were significantly (p < 0.05) decreased in the group compared with the CON dogs. Fecal total lactic acid bacteria counts were significantly (p < 0.05) increased in the LAP treatment. In conclusion, the supplementation of LAP in Beagle dog diets could decrease the blood triglyceride level and enhance the gut Lactobacillus count which may have positive effects on dogs.

Effect of Several Solvent Extracts from Paeoniae Radix on Experimental Hyperlipidemia in Rats (고지혈증 랫트를 이용한 작약의 수종 용매 추출물에 의한 항고지혈 효과)

  • Ro, Hwan-Seong;Ko, Woo-Kyoung;Yang, Hyun-Ok;Park, Kun-Koo;Cho, Young-Hwan;Park, Hyoung-Sup
    • Journal of Pharmaceutical Investigation
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    • v.27 no.2
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    • pp.145-151
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    • 1997
  • Hexane, chloroform, methanol and water extracts of Paeoniae Radix were tested on the experimentally induced hypercholesterolemia in rats for lowering effect of serum lipoprotein contents. Hyperlipidemia was induced on male Wistar rats by feeding high cholestetrol diet for 7 days. Serum lipid profile was verified on these rats by measuring total cholesterol (TC), triglyceride (TG), high density lipoprotein cholesterol (HDL), and low density lipoprotein cholesterol (LDL). Then, the diet was changed to normal. At the same time, hexane, chloroform, methanol and water extract of Paeoniae Radix were given orally on daily basis, and the changes in the serum lipid profile were assessed for 4 weeks. Methanol extract of Paeoniae radix decreased TC level at 1, 2, and 4 week point significantly, and water extract decreased TC level at 4 week point significantly comparing with the control group.

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The effect of 60%HRmax exercise program in LDL-C, HDL-C (60%HRmax 운동프로그램이 혈중 저밀도, 고밀도 콜레스테롤 수치 변화에 미치는 영향)

  • Nam, Hyoung-Chun;Lee, Geon-Cheol
    • Journal of Korean Physical Therapy Science
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    • v.9 no.4
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    • pp.25-33
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    • 2002
  • The purpose of this study is to investigate the effect of 60%HRmax exercise program on LDL-C, HDL-C. The subject of this study, 16 female university students in Seoul, who are randomly sampled and divided into two groups : experimental group (N=8), and control group (N=8). The following results are obtained this study: First the LDL-C levels of two groups are not significantly different in the training period. The LDL-C level of experimental group decreased in after-exercise(4 week, 8 week) in comparison with before-exercise. Specially it decrease significant after 4 week exercise. And it is no significant difference in control group. Second, the HDL-C levels of two groups are not significantly different before exercise but are significant different after exercise(4 week, 8 week). Although the HDL-C level of the experimental group decrease in after-exercise(4 week, 8 week), but it is not significant decrease. And it is not significant difference in control group.

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Subclinical Hypothyroidism;Controversial Subjects and Therapeutic Regimen (준임상적 갑상선기능저하증;논란이 되는 주제들)

  • Park, Ji-Hun;Kim, Ho-Jun;Lee, Myeong-Jong
    • Journal of Korean Medicine for Obesity Research
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    • v.6 no.2
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    • pp.29-41
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    • 2006
  • Subclinical hypothyroidism is defined as a normal serum free thyroxine level combined with an elevated thyroid stimulating hormone level. The causes of subclinical hypothyroidism are the same as those of overt hypothyroidism. There is good evidence that subclinical hypothyroidism is associated with progression to overt disease. The management of subclinical hypothyroidism is remains controversial. Patients with a serum thyroid stimulating hormone level greater than 10 mU/L have a higher incidence of elevated serum low-density lipoprotein cholesterol concentrations; however, evidence is lacking for other associations. There is insufficient evidence that hormone treatment of subclinical hypothyroidism is beneficial. The use of thyroid stimulating hormone level lone as a diagnostic and assessment tool for hypothyroidism is inadequate because this test cannot identify numerous conditions this sentence is unclear in its meaning. Using an expanded list of clinical signs and symptoms associated with dysfunction of the Hypothalamus-Pituitary-Thyroid axis, it is possible to hypothesize that subclinical hypothyroidism may be more common in a population of patients with early signs of age-related diseases than most practitioners realize. To improve thyroid function in subclinical hypothyroidism patients, practitioners should become familiar with foods and nutrients that can hinder or support thyroid function.

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Effects of seaweed supplementation on blood glucose concentration, lipid profile, and antioxidant enzyme activities in patients with type 2 diabetes mellitus

  • Kim, Min-Sun;Kim, Jung-Yun;Choi, Woong-Hwan;Lee, Sang-Sun
    • Nutrition Research and Practice
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    • v.2 no.2
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    • pp.62-67
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    • 2008
  • The present study was carried out to evaluate the physiological effects of seaweed supplementation on blood glucose levels, lipid profile, and antioxidant enzyme activities in subjects with type 2 diabetes mellitus. Subjects were randomized into either a control group or a seaweed supplementation group. Pills with equal parts of dry powdered sea tangle and sea mustard were provided to the seaweed supplementation group three times a day for 4 weeks. Total daily consumption of seaweed was 48 g. We found that total dietary fiber intake was 2.5 times higher in subjects receiving seaweed supplementation than in the control group. Accordingly, fasting blood glucose levels (p<0.01) and 2-hour postprandial blood glucose measurements (p<0.05) were decreased significantly in those ingesting seaweed. Furthermore, the serum concentrations of triglycerides were decreased and high-density lipoprotein cholesterol was increased significantly in seaweed supplement group (p<0.05). However, the concentrations of total cholesterol and low-density lipoprotein cholesterol were not affected by seaweed supplementation. The level of thiobarbituric acid reactive substances in erythrocytes was significantly lower with seaweed supplementation compared to controls (p<0.05). Catalase and glutathione peroxidase activities with seaweed supplementation were higher than the controls (p<0.05), but superoxide dismutase activity was not affected. We, therefore, conclude that ingestion of seaweed influences glycemic control, lowers blood lipids, and increases antioxidant enzyme activities.