• Title, Summary, Keyword: larynx

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A case of Adenocarcinoma of the Larynx (후두 선암종 1례)

  • 이윤식;남순열
    • Korean Journal of Bronchoesophagology
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    • v.4 no.2
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    • pp.258-261
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    • 1998
  • Most laryngeal carcinomas are squamous cell carcinomas. Adenocarcinoma of the larynx is rare, its incidence has been reported less than 1% of all laryngeal neoplasms. Adenocarcinoma arises from glandular structures of the larynx and usually arises from the supraglottis. Compared to other carcinoma, deep biopsy and aggressive treatment is manditory. We report a case of adenocarcinoma of the larynx with review of current literatures.

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Evaluation of Larynx Cancer via Chemometrics Assisted Raman Spectroscopy

  • Senol, Onur;Albayrak, Mevlut
    • Current Optics and Photonics
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    • v.3 no.2
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    • pp.150-153
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    • 2019
  • Larynx cancer is a potentially terminal and severe type of neck and head cancer in which malignant cells start to grow and spread upwards in the larynx, or voice box. Smoking tobacco, drinking hot beverages and drinking alcohol are the main risk factors for these tumors. In this study, we aimed to develop a precise, accurate and rapid chemometrics assisted Raman spectroscopy method for diagnosis of larynx cancer in deparaffinized tissue samples. In the proposed method, samples were deparaffinized and 20 microns of each tissue were located on a coverslip. Both healthy (n = 13) and cancerous tissues (n = 13) were exposed to a Raman laser (785 nm) and excitations were recorded between wavenumbers of $50{\sim}1500cm^{-1}$. An Orthogonal Partial Least Square algorithm was applied to evaluate the Raman spectrum obtained. Sensitivity and specificity of the proposed method is high enough with the aid of Principal Component Analysis (PCA) to test the whole model. Healthy and cancerous tissues were accurately and precisely clustered. A rapid, easy and precise diagnosis algorithm was developed for larynx cancer. By this method, some useful data about differences in biomolecules of each group (phospholipids, amides, tyrosine, phenylalanine collagen etc.) was also obtained from the spectra. It is claimed that the optimized method has a great potential for clustering and separating tumor tissues from healthy ones. This novel, rapid, precise and objective diagnosis method may be an alternative for the conventional methods in literature for diagnosis of larynx cancer.

Treatment of Larynx Granuloma (후두육아종의 치료)

  • 주준범;홍석중;강보현;김영진;유승주;김상윤;남순열
    • Korean Journal of Bronchoesophagology
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    • v.7 no.1
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    • pp.19-23
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    • 2001
  • Background and Objectives: Larynx granuloma is a exophytic inflammatory mass and may result from gastroesophageal reflux disease and a traumatic or prolonged endotracheal intubation. There has been a controversy in the treatment of larynx granuloma. Our aim of study is to know the results of the conservative management and surgery for larynx granuloma. Materials and Methods : We have reviewed and analyzed medical records of 71 Patients who were diagnosed and treated as larynx granuloma in Asan medical center from 1989 to 2000 retrospectively. And questionnaires on present patient's status were answered via telephone. Results : Forty four cases were treated by conservative management and 29 cases were treated by surgery. The total Percentages of improvement after treatment were 85.7 o/o after conservative management and 75.9% after surgery. In intubation granuloma percentages of improvement were 86.4% after conservative management and 73% after surgery. In contact granuloma percentages of improvement were 85% after conservative management and 78.5% after surgery. Conclusion : Resolution and treatment periods are longer in contact granuloma compared to intubation granuloma in the groups of conservative management. (P<0.05) There is no significant difference of their outcome between conservative management and surgery. (P>0.05) Although this study is retrospective, conservative management is the first treatment in the management of larynx granuloma.

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A Study for the Changes of Laryngeal Position and Vocal Pitch with Ageing Process (연령에 따른 정상인의 후두 위치 및 발화 기저주파수의 변화에 대한 연구)

  • 홍기환;김현기;정경수;윤희완;김성완
    • Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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    • v.9 no.1
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    • pp.79-85
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    • 1998
  • Changes in the human voice occur between infancy and old age and reflect a myriad of biological changes that influence the size, shape, and physical properties of the larynx. The human larynx is located near the base of the neck and attached inferiorly to the trachea and opens superiorly into the pharynx. The larynx by the third month of fetal life has the same features recognizable at birth. The fundamental frequency of vocal fold vibration generally becomes higher in early age, lower in middle age, and higher in old age. These decreases in Fo undoubtedly result from a combination of factors, consisting of modest increase in length and mass of the muscle and connective tissues of the vocal fold. But the level of the larynx in the neck may be closely connected with Fo directly, high larynx in related with high pitch and low larynx with low pitch. The purpose of this study is to determine the developmental level difference from child to adult larynx using conventional radiography, and the change of speaking fundamental frequency from second decade to sixth decade.

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Three Cases of Neuroendocrine Carcinoma of the Larynx (후두에 발생한 신경 내분비암종 3예)

  • Yeo, Nam-Kyung;Choi, Seung-Ho;Kim, Sang-Yoon;Nam, Soon-Yuhl
    • Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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    • v.16 no.1
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    • pp.76-80
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    • 2005
  • Although primary neuroendocrine carcinomas(NEC) are uncommon tumors of the larynx, they represent the most common nonepidermoid malignancy of this organ. Whereas typical carcinoid tumors and small-cell carcinomas occur very rarely in the larynx, the majority of laryngeal NEC belong to a broad intermediate group between these two extremes of NEC. Through many case studies, a major protion of clinicopathologic characteristics of laryngeal NEC have been revealed; however, the gistogenesis of laryngeal NEC is still unknown. The only well-documented normal neuroendocrine structures of the larynx are paraganglions, but the incidence of laryngeal paragangliomas are much lower than that of NEC. Here, we report on three cases of NEC affecting the larynx and the results of searching for neuroendocriene cells in non-neoplastic larynx tissue.

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Neutrophil-lymphocyte Ratio Findings and Larynx Carcinoma: a Preliminary Study in Turkey

  • Duzlu, Mehmet;Karamert, Recep;Tutar, Hakan;Karaloglu, Furkan;Sahin, Melih;Cevizci, Rasit
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.1
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    • pp.351-354
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    • 2015
  • Background: To identify the potential prognostic role of the neutrophil/lymphocyte (N/L) ratio in larynx carcinoma. Materials and Methods: Oncologic archive charts of patients with a larynx carcinoma diagnosis between the years 2010 and 2013 were retrospectively reviewed. The inclusion criterion was to be available with hemogram test prior to diagnostic procedure. Patients undergoing septorinoplasty comprised the control group. Results: There were 65 cases in the study and 42 cases in control group meeting inclusion criteria. In general a non-significant increase in N/L ratio was observed with increasing tumor size and stage (p>0.05) in larynx carcinoma. The N/L ratio was found to be significantly higher in larynx carcinoma compared to control group (p=0.004). Conclusions: In conclusion, the N/L ratio was shown to be significantly increased in larynx carcinomas compared to control group. Further studies are needed to assess any prognostic role.

A Case of the Laryngopharyngeal Burn Caused by A Microwave-Heated Egg Bite

  • Won, Seong Jun;Woo, Seung Hoon
    • Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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    • v.24 no.2
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    • pp.122-124
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    • 2013
  • Nowadays, microwave ovens are commonly used for cooking. However, the cooking certain food in microwave ovens can be hazardous. It has been reported that the heating eggs in a microwave oven can cause an explosion and injuries. The exploding eggs can cause burn injury of face, neck, eyelid, pharynx and larynx. Direct thermal damage to the larynx after swallowing microwave-heated eggs is rare. The authors report a larynx thermal injury due to microwave-heated eggs and review the cause and the prevention methods of exploding eggs.

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A Case of Malignant Lymphoma of the Larynx (후두에 발생한 원발성 악성임파종 1례)

  • 우훈영;고건성;이희배;전시영;오경균;백만기
    • Proceedings of the KOR-BRONCHOESO Conference
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    • pp.6.3-6
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    • 1978
  • The purpose of this paper is to review the literature concerning the occurence of malignant lymphoma of the larynx and to add a case. Mackenty was the first to report a case of malignant lymphoma involving the larynx, 1934. After then 28 cases were reported of which 8 were described as primary in the larynx. Yet no case was reported in our nation. We experienced a case of primary malignant lymphoma of the larynx in 10 years old male and report with consideration of literature concerning the same disease.

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A Case of Metachronous Multiple Primary Tumor Involving the Thyroid and the Larynx (갑상선과 후두에 발생한 다발성 원발암 1례)

  • 손영익;권중근;추광철
    • Korean Journal of Bronchoesophagology
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    • v.3 no.1
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    • pp.164-168
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    • 1997
  • Multiple primary tumors in the head and neck are not uncommon, however those in the thyroid and the larynx are known to be very rare. In most cases of multiple primary tumors involving the thyroid and the larynx, lesions are observed usually simultaneously and thyroid tumors are found incidentally during the laryngeal tumor surgery. In rare cases, thyroid tumors are found metachronously after radiation therapy of laryngeal cancer. The authors recently experienced a case of multiple primary tumor involving the thyroid and the larynx, in which thyroid papillary carcinoma was the index tumor and the laryngeal squamous carcinoma was the meatachronous second tumor. Both tumors showed aggressive local extension and regional nodal meatastasis with tumor collision in the same node. The patient died of recurrent or of residual squamous carcinoma shortly after main surgical treatment index thyroid cancer.

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A Case of Recurred Sarcomatoid Carcinoma of Larynx after Postoperative Radiotherapy (술후 방사선 치료 후 재발한 후두 육종양 암종 (Sarcomatoid Carcinoma) 1예)

  • Jeong, Jun-Hui;Lim, Beom-Jin;Ro, Jae-Y.;Choi, Hong-Shik
    • Korean Journal of Head & Neck Oncology
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    • v.26 no.2
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    • pp.236-239
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    • 2010
  • Sarcomatoid carcinoma is a rare carcinoma which arises from upper respiratoy system, gastrointestinal tract, urinary tract and skin. Sarcomatoid carcinoma of larynx is rare so pathogenesis, clinical behavior, treatment and prognosis of it is being debated. Treatment of sarcomatoid carcinoma of larynx is similar to squamous cell carcinoma of larynx. We report a case of recurred sarcomatoid carcinoma after surgical treatment and postoperative radiotherapy.