• Title, Summary, Keyword: international scoring system

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International Scoring System in Symptomatic Multiple Myeloma: Experience from a Tertiary Care Center

  • Sultan, Sadia;Irfan, Syed Mohammed;Parveen, Saira;Taufiq, Ufaq
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.4
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    • pp.2031-2033
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    • 2016
  • Background: Symptomatic multiple myeloma (MM) is an acquired B-cell malignant proliferation of antibody secreting plasma cells, characterized by end organ damage due to monoclonal immunoglobulin secretion. The aim of this study wa to determine the stage stratification according to an international scoring system in adult Pakistani MM patients at presentation. Materials and Methods: This single centre retrospective study extendedfrom January 2012 to December 2015. Data were retrieved from the departmental maintained records. Results: A total of 39 patients were diagnosed at our center with MM during the period of the study, 25 males and 14 females. Age ranged between 36 and 81 with a mean of $54.5{\pm}14.8$ and a median of 57 years. Common presenting complaints included fatigue (80.9%), backache (79.3%) and bone pain (66.2%). Overall, 9 patients were in ISS stage I (23%), 12 were in stage II (30.7%) and 18 were in stage III (46.1%). Out of the total, 29 (74.3%) had kappa immunoglobulin andthe remaining 10 (25.6%) had lambda type myelomas. IgG myeloma was commonest, seen in 26 (66.6%) followed by IgA in 11 (28.2%) with non secretory myeloma in one (2.5%) and light chain disease also in one patient (2.5%). Conclusions: MM in Pakistani patients is seen in a relatively young population with male predominance. Primarily patients are symptomatic and risk stratification revealed a predominance of advanced stage III disease in our setting.

Development and Application of a Chemical Ranking and Scoring System for the Management of Endocrine Disrupting Chemicals (환경성 내분비계장애물질(EDCs)의 우선관리순위 결정법 개발 및 적용)

  • Lim, Miyoung;Park, Ji Young;Ji, Kyunghee;Lee, Kiyoung
    • Journal of Environmental Health Sciences
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    • v.44 no.1
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    • pp.76-89
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    • 2018
  • Background: Exposure to endocrine disrupting chemicals (EDCs) has been considered one of the main causes of a range of endocrine diseases in modern society. An EDC priority list considering exposure, toxicity, and societal concern should be established for EDC management. Methods: The chemical ranking and scoring (CRS) system for EDCs was based on exposure, toxicity,and societal concern. The exposure score system was based on usage, circulation volume, bioaccumulation, and detection in consumer products. The toxicity score system was based on carcinogenicity and reproductive and developmental toxicity. The societal concern score system was based on domestic or international regulations and mass media reports. Results: A total of 165 EDCs were considered in the CRS system. The top-five priority EDCs were Bis(2-ethylhexyl) phthalate (DEHP), Benzene, Bisphenol A, Dibutyl phthalate (DBP) and Trichloroethylene. Phthalates, bisphenols and parabens were identified as priority chemical groups. Conclusion: We developed a CRS system for EDCs to identify priority EDCs for management. This will be a foundation to provide an EDC management plan based on scientific decision-making.

A Study on Certification Activities on Aerospace Quality Management System (항공 품질경영시스템 인증활동에 관한 연구)

  • Lee, Sung-Ju;Byun, Jai-Hyun
    • Journal of the Korean Society for Quality Management
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    • v.35 no.3
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    • pp.88-99
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    • 2007
  • The AS9100 aerospace standard has become the aerospace quality management system standard instead of ISO9001 and MIL-Q-9858A by international aerospace manufacturing companies. The organization which adopts AS9100 standard is to be certified by an independent third party certification body as IAQG requests. The quality management system certification assessor shall utilize the AS9101 standard prepared by IAQG to assess AS9100 organization. In this paper, AS9101 quality system questionnaire is analyzed and scoring method which characterizes AS9101 is reviewed. Score attained can be utilized as an organizational quality index. Practical data gathered by certified assessors from 2002 to 2007 are analyzed and suggested to improve the organization's system operational efficiency based on the analysis results. Suggestions can be utilized by any organization to prepare assessment or to enhance the level of quality system maturity. This study is applicable to the future as well as present aerospace manufacturing activities throughout the world.

Prioritization of Anti-Icing Spray System for Active Snow-Removal Works (능동적 제설작업을 위한 염수분사장치 설치 우선순위 선정)

  • Yang, Choong Heon;Kim, In Su
    • International Journal of Highway Engineering
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    • v.17 no.4
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    • pp.99-105
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    • 2015
  • PURPOSES: This study aims to establish the priority of introducing anti-icing spray system for regions of the National Highways in South Korea. Using this study, a logical plan for instituting such an anti-icing spray system can be established for the National Highways. METHODS : The Analytical Hierarchy Process (AHP) was employed to prioritize the implementation of an anti-icing spray system on Korean highways. For this purpose, an existing scoring table developed by the Ministry of Land, Infrastructure Transport Affair was slightly modified in order to reflect recent trends in winter maintenance. A survey was conducted to gather the preferences regarding the developed hierarchy of road experts and agencies. Finally, the final score was produced by integrating the scoring results with estimated weights for each evaluation criterion. RESULTS: In general, Honam and the metropolitan areas have relatively high priority while other areas such as Chungcheong, Young Nam, and Gang Won appear to be uniform in importance in terms of establishing an anti-icing spray system. This result may indicate that historical weather data and traffic volumes are significant factors in deciding in winter maintenance polices CONCLUSIONS : In this study, useful insights are suggested regarding winter maintenance by simultaneously performing rapid snow removal and proactive treatment. Issues of resource allocation may be potential research items in the field transportation engineering.

Development of the anti-cancer food scoring system 2.0: Validation and nutritional analyses of quantitative anti-cancer food scoring model

  • Hong, Yeo-Jin;Kim, Jeongseon;Lee, Hye Yoon;Rim, Chai Hong
    • Nutrition Research and Practice
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    • v.14 no.1
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    • pp.32-44
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    • 2020
  • BACKGROUND/OBJECTIVE: We have previously designed the anti-cancer food scoring model (ACFS) 1.0, an evidence-based quantitative tool analyzing the anti-cancer or carcinogenic potential of diets. Analysis was performed using simple quantitative indexes divided into 6 categories (S, A, B, C, D, and E). In this study, we applied this scoring model to wider recipes and evaluated its nutritional relevance. MATERIALS/METHODS: National or known regional databases were searched for recipes from 6 categories: Korean out-dining, Korean home-dining, Western, Chinese, Mediterranean, and vegetarian. These recipes were scored using the ACFS formula and the nutrition profiles were analyzed. RESULTS: Eighty-eight international recipes were analyzed. All S-graded recipes were from vegetarian or Mediterranean categories. The median code values of each category were B (Korean home-dining), C (Korean out-dining), B (Chinese), A (Mediterranean), S (vegetarian), and D (Western). The following profiles were correlated (P < 0.05) with ACFS grades in the univariate trend analysis: total calories, total fat, animal fat, animal protein, total protein, vitamin D, riboflavin, niacin, vitamin B12, pantothenic acid, sodium, animal iron, zinc, selenium, and cholesterol (negative trends), and carbohydrate rate, fiber, water-soluble fiber, vitamin K, vitamin C, and plant calcium (positive trends). Multivariate analysis revealed that animal fat, animal iron, and niacin (negative trends) and animal protein, fiber, and vitamin C (positive trends) were statistically significant. Pantothenic acid and sodium showed non-significant negative trends (P < 0.1), and vitamin B12 showed a non-significant positive trend. CONCLUSION: This study provided a nutritional basis and extended the utility of ACFS, which is a bridgehead for future cancer-preventive clinical trials using ACFS.

A Study On Advanced Model of Web Vulnerability Scoring Technique (웹 취약점 스코어링 기법의 advanced 모델 연구)

  • Byeon, Autumn;Lim, Jong In;Lee, Kyong-Ho
    • Journal of the Korea Institute of Information Security & Cryptology
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    • v.25 no.5
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    • pp.1217-1224
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    • 2015
  • Web application security problems are addressed by the web vulnerability analysis which in turn supports companies to understand those problems and to establish their own solutions. Ministry of Science, ICT and Future Planning (MSIP) has released its guidelines for analysis and assessment of the web vulnerability. Although it is possible to distinguish vulnerability items in a manner suggested in the MSIP's guidelines, MSIP's factors and criteria proposed in the guidelines are neither sufficient nor efficient in analyzing specific vulnerability entries' risks. This study discusses analysis of the domestic and international Vulnerability Scoring system and proposes an appropriate evaluating method for web vulnerability analysis.

Bioinformatics Approach to Direct Target Prediction for RNAi Function and Non-specific Cosuppression in Caenorhabditis elegans (생물정보학적 접근을 통한 Caenorhabditis elegans 모델시스템의 생체내 RNAi 기능예측 및 비특이적 공동발현억제 현상 분석)

  • Kim, Tae-Ho;Kim, Eui-Yong;Joo, Hyun
    • KSBB Journal
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    • v.26 no.2
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    • pp.131-138
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    • 2011
  • Some computational approaches are needed for clarifying RNAi sequences, because it takes much time and endeavor that almost of RNAi sequences are verified by experimental data. Incorrectness of RNAi mechanism and other unaware factors in organism system are frequently faced with questions regarding potential use of RNAi as therapeutic applications. Our massive parallelized pair alignment scoring between dsRNA in Genebank and expressed sequence tags (ESTs) in Caenorhabditis elegans Genome Sequencing Projects revealed that this provides a useful tool for the prediction of RNAi induced cosuppression details for practical use. This pair alignment scoring method using high performance computing exhibited some possibility that numerous unwanted gene silencing and cosuppression exist even at high matching scores each other. The classifying the relative higher matching score of them based on GO (Gene Ontology) system could present mapping dsRNA of C. elegans and functional roles in an applied system. Our prediction also exhibited that more than 78% of the predicted co-suppressible genes are located in the ribosomal spot of C. elegans.

Comparison of Cervical Cell Morphology Using Two Different Cytology Techniques for Early Detection of Pre-Cancerous Lesions

  • Moosa, Najla Yussuf;Khattak, Nuzhat;Alam, Muhammad Irfan;Sher, Alam;Shah, Walayat;Mobashar, Shumaila;Alam, Muhammad Imran;Javid, Asima
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.2
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    • pp.975-981
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    • 2014
  • Cervical cancer is an issue of foremost importance globally, specifically affecting the developing nations. Significant advances have taken place with regard to diagnosis of cervical cancer, especially with screening. Appropriate screening measures can thus reduce the incidence of cervical cancer. The most desirable screening technique should be less invasive, easy to perform, cost-effective and cover a wide range of diagnostic icons. Manual liquid based cytology (MLBC) can be considered as one of the suitable technique for screening with the above-mentioned benefits. The aim of the current study was to compare two cervical screening techniques on the basis of different morphological parameters and staining parameters by using modified acetic acid Pap staining to see the possibility of reducing time economy involved in conventional Pap staining (CPS). The study was conducted on a total 88 cases and all were analyzed with both MLBC and CPS. Forty eight cases that were regarded as satisfactory on the basis of Bethesda system by both methods were further recruited for investigation. Their morphological parameters and staining quality were compared and scored according to a scoring system defined in the study. Quality indices was calculated for both staining procedures and smear techniques.

The Comparative Study on Arbitration System of South Korea, North Korea, and China (남북한 및 중국 중재제도의 비교연구)

  • Shin, Koon-Jae;Lee, Joo-Won
    • Journal of Arbitration Studies
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    • v.17 no.2
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    • pp.101-124
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    • 2007
  • The legal systems and open-door policies to foreign affairs in North Korea have been followed by those of China. Whereas an arbitration system of South Korea accepted most parts of UNCITRAL Model Law, North Korea has succeeded to an arbitration system of a socialist country. China, under the arbitration system of socialist country, enacted an arbitration act reflected from UNCITRAL Model Law for keeping face with international trends. We have used these three arbitration system as a tool for analyzing an arbitration system in North Korea. With an open-door policy, North Korea and China enacted an arbitration act to provide a legal security. Therefore, the core parts of arbitration system in North Korea and China are based on a socialist system while those of South Korea is on liberalism. So, North Korea and China enacted an arbitration act on the basis of institutional arbitration, on the other side, South Korea is based on ad-hoc arbitration. Because of these characters, in terms of party autonomy, it is recognized with the order as South Korea, China and North Korea. Also North Korea enacted separate 'Foreign Economic Arbitration Act' to resolve disputes arising out of foreign economies including commercial things and investments. There are differences in arbitration procedures and appointment of arbitrators : South Korea recognizes parties' autonomy, however parties should follow the arbitration rules of arbitration institutes in North Korea and China. According to an appointment of arbitrators, if parties fail to appoint co-arbitrators or chief arbitrators by a mutual agreement, the court has the right to appoint them. In case of following KCAB's rules, KCAB secretariats take a scoring system by providing a list of candidates. A party has to appoint arbitrators out of the lists provided by arbitration board(or committee) in North Korea. If a party may fail to appoint a chief arbitrator, President of International Trade Arbitration Board(or Committee) may appoint it. In China, if parties fail to appoint a co-arbitrator or a chief arbitrator by a mutual agreement, Secretary general will decide it. If a arbitral tribunal fails to give a final award by a majority decision, a chief arbitrator has the right for a final decision making. These arbitration systems in North Korea and China are one of concerns that our companies take into account in conducting arbitration procedures inside China. It is only possible for a party to enforce a final arbitral award when he applies an arbitration inside North Korea according to International Trade Arbitration Act because North Korea has not joined the New York Convention. It's doubtful that a party might be treated very fairly in arbitration procedures in North Korea because International Trade Promotion Commission controls(or exercises its rights against) International Trade Arbitration Commission(or Board).

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The Research of Pain and Functional Disability Assessment Scales for Knee Joint Disease (슬관절의 통증과 기능장애의 평가도구에 관한 연구)

  • Jung, Chan-Yung;Kim, Eun-Jung;Hwang, Min-Seop;Cho, Hyun-Seok;Kim, Kyung-Ho;Lee, Seung-Deok;Kim, Kap-Sung
    • Journal of Acupuncture Research
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    • v.27 no.2
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    • pp.123-142
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    • 2010
  • Objectives : The knee pain is the main reason of getting acupuncture treatment. In order to have confidence in the results of a study, it is necessary to establish that questionnaire is both valid and reliable in questionnaire related study. The aim of this study was to review the instruments that are currently in sue for assessing the knee joint. Methods : A literature study was performed to choose appropriate scales for assessment for pain and the function of the knee. Theoretically based scales were selected for review. Therefore, 18 scales for knee and 9 scale for pain were reviewed. the status of scales involved in knee treatment of acupuncture throughout several countries was evaluated. Results & Conclusion : Lysholm Knee Scoring Scale, Cincinnati knee rating system(CKRS) are adequate for ligament injury in knee. International Knee Documentation Committee scoring system(IKDC) may become a publication requirement for journals in view of the international standing of the committee. The available outcome measure for use in osteoarthritis are Western Ontario and McMaster Universities Osteoarthritis Index(WOMAC), Lequesne Functional Severity Index(LFI) and Knee Injury and Osteoarthritis Outcome Score(KOOS), and in rheumatoid arthritis are McMaster-Toronto Arthritis patient function preference questionnaire(MACTAR), Quality of Life-Rheumatoid Arthritis Scale(QoL-RA Scale). Visual analog scale(VAS), verbal rating scale(VRS) are commonly used for the standard pain scale. For long term follow-up study The Medical Outcomes Study Short Form-36(SF-36), Arthritis Impact Measurement Scales(AIMS), Health Assessment Questionnaire(HAQ) should be included. Each measurement has its own composition and characteristics. Their validity, reliability, responsiveness and practical characteristics were already evaluated. We found 20 domestic and 28 overseas papers about knee treatment using acupuncture assessed with knee scales.