• Title, Summary, Keyword: immune system

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Stress and Immune Function (스트레스와 면역기능)

  • Koh, Kyung-Bong
    • Korean Journal of Psychosomatic Medicine
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    • v.4 no.1
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    • pp.146-154
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    • 1996
  • The impact of stress on immune function is known to be associated with the interactions among the central nervous system(CNS), neuroendocrine system, and immune system. The main pathways between stress and immune system are wiring of lymphoid organs and neuroendocrine system. Immune system also produces neuropeptides, which modulate immune system. Mediators of psychosocial influences on immune function are found to be peptides released by the pituitry, hormones, md autonomic nervous system. Hypothalamus integrates endocrine, neural and immune systems. Particularly, paraventricular nucleus appears to play a central role in this integration. On the other hand, endocrine system receives feedback from the immune system. The major regulatory pathways which pituitary modulates include the hypothalamic-pituitary-adrenal-thymic(HPAT) axis, hypothalamic-pituitary-gonadal-thymic(HPGT) axis, pineal-hypothalamic-pituitary(PHP) axis. Bidirectional pathways such as feedforward and feedback pathways are suggested in the interaction between stress and immune system. It suggests that psychosocial inputs affect immune function, but also that immunological inputs affect psychosocial function. Thus, prospective studies for elucidating the relationship between stress and immune function should incorporate measures of immune function as well as measures of endocrine, autonomic, and brain activities at the same time.

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A Study on Network detection technique using Human Immune System (인간 면역 체계를 이용한 네트워크 탐지기술 연구)

  • ;Peter Brently
    • Proceedings of the Korea Inteligent Information System Society Conference
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    • pp.307-313
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    • 1999
  • This paper reviews and assesses the analogy between the human immune system and network intrusion detection systems. The promising results from a growing number of proposed computer immune models for intrusion detection motivate this work. The paper begins by briefly introducing existing intrusion detection systems (IDS's). A set of general requirements for network-based IDS's and the design goals to satisfy these requirements are identified by a careful examination of the literature. An overview of the human immune system is presented and its salient features that can contribute to the design of competent network-based IDS's are analysed. The analysis shows that the coordinated actions of several sophisticated mechanisms of the human immune system satisfy all the identified design goals. Consequently, the paper concludes that the design of a network-based IDS based on the human immune system is promising for future network-based IDS's

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A Study on Network detection technique using Human Immune System (인간 면역 체계를 이용한 네트워크 탐지기술 연구)

  • ;Peter Brently
    • Proceedings of the Korea Database Society Conference
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    • pp.307-313
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    • 1999
  • This paper reviews and assesses the analogy between the human immune system and network intrusion detection systems. The promising results from a growing number of proposed computer immune models for intrusion detection motivate this work. The paper begins by briefly introducing existing intrusion detection systems (IDS's). A set of general requirements for network-based IDS's and the design goals to satisfy these requirements are identified by a careful examination of the literature. An overview of the human immune system is presented and its salient features that can contribute to the design of competent network-based IDS's are analysed. The analysis shows that the coordinated actions of several sophisticated mechanisms of the human immune system satisfy all the identified design goals. Consequently, the paper concludes that the design of a novel network-based IDS based on the human immune system is promising for future network-based IDS's

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On Designing a Robot Manipulator Control System Using Multilayer Neural Network and Immune Algorithm (다층 신경망과 면역 알고리즘을 이용한 로봇 매니퓰레이터 제어 시스템 설계)

  • 서재용;김성현;전홍태
    • Proceedings of the Korean Institute of Intelligent Systems Conference
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    • pp.267-270
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    • 1997
  • As an approach to develope a control system with robustness in changing control environment conditions, this paper will propose a robot manipulator control system using multilayer neural network and immune algorithm. The proposed immune algorithm which has the characteristics of immune system such as distributed and anomaly detection, probabilistic detection, learning and memory, consists of the innate immune algorithm and the adaptive immune algorithm. We will demonstrate the effectiveness of the proposed control system with simulations of a 2-link robot manipulator.

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Optimization of Distributed Autonomous Robotic Systems Based on Artificial Immune Systems

  • Hwang, Chul-Min;Park, Chang-Hyun;Sim, Kwee-Bo
    • Proceedings of the Korean Institute of Intelligent Systems Conference
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    • pp.220-223
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    • 2003
  • In this paper, we optimize distributed autonomous robotic system based on artificial immune system. Immune system has B-cell and T-cell that are two major types of lymphocytes. B-cells take part in humoral responses that secrete antibodies and T-cells take part in cellular responses that stimulate or suppress cells connected to the immune system. They have communicating network equation, which have many parameters. The distributed autonomous robotics system based on this artificial immune system is modeled on the B-cells and T-cells system. So performance of system is influenced by parameters of immune network equation. We can improve performance of Distributed autonomous robotics system based on artificial immune system.

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A Design of An Active PID control using Immune Algorithm for Vibration Control of Building Structure (구조물 진동제어를 위한 Immune Algorithm을 이용한 Active PID 제어기 설계)

  • Lee, Young-Jin;Cho, Hyun-Cheol;Lee, Kwon-Soon
    • Proceedings of the KIEE Conference
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    • pp.72-74
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    • 2005
  • In this paper, we propose an adaptive PID controller using a cell-mediated immune response to improve a PID control performance. The proposed controller is based on the specific immune response of the biological immune system that is cell-mediated immunity. The immune system of organisms in the real body regulates the antibody and the T-cells to protect an attack from the foreign materials like virus, germ cells, and other antigens. It has similar characteristics that are the adaptation and robustness to overcome disturbances and to control the plant of engineering application. We first build a model of the T-cell regulated immune response mechanism and then designed an I-PID controller focusing on the T-cell regulated immune response of the biological immune system. We apply the proposed methodology to building structures to mitigate vibrations due to strong winds for evaluation of control performances. Through computer simulations, system responses are illustrated and additionally compared to traditional control approaches.

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Introduction to a Novel Optimization Method : Artificial Immune Systems (새로운 최적화 기법 소개 : 인공면역시스템)

  • Yang, Byung-Hak
    • IE interfaces
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    • v.20 no.4
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    • pp.458-468
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    • 2007
  • Artificial immune systems (AIS) are one of natural computing inspired by the natural immune system. The fault detection, the pattern recognition, the system control and the optimization are major application area of artificial immune systems. This paper gives a concept of artificial immune systems and useful techniques as like the clonal selection, the immune network theory and the negative selection. A concise survey on the optimization problem based on artificial immune systems is generated. The overall performance of artificial immune systems for the optimization problem is discussed.

A Vibration Control of the Strcture using Immune Response Algorithm (면역반응 알고리즘을 이용한 구조물의 진동제어)

  • 이영진;이권순
    • Journal of Korean Port Research
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    • v.13 no.2
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    • pp.389-398
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    • 1999
  • In the biological immunity, the immune system of organisms regulates the antibody and T-cells to protect the attack from the foreign materials which are virus, germ cell, and other antigens, and supports their stable state. It has similar characteristics that has the adaptation and robustness to overcome disturbances and to control the plant of engineering application. In this paper, we build a model of the T-cell regulated immune response mechanism. We have also designed an immune response controller(IRC) focusing on the T-cell regulated immune response of the biological immune system that include both a help part to control the response and a suppress part to adjust system stabilization effect. We show some computer simulation to control the vibration of building structure system with strong wind forces excitation also demonstrate the efficiency of the proposed controller for applying a practical system even with existing nonlinear terms.

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Aging of Immune System (면역 반응체계의 노화)

  • Chung, Kyung Tae
    • Journal of Life Science
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    • v.29 no.7
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    • pp.817-823
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    • 2019
  • Immune system provides defense integrity of body against external invaders. In order to accomplish the important defending role immune system is composed of many different components which are regenerated continuously during lifespan. The key components are professional killing cells such as macrophage, neutrophil, natural killer cell, and cytotoxic T cell and professional blocking molecule, antibody, which is produced by plasma cell, the terminal differentiated B cell. Immune response is orchestrated harmoniously by all these components mediated through antigen presenting cells such as dendritic cells. Immune responses can be divided into two ways: innate immune response and adaptive immune response depending on induction mechanism. Aging is a broad spectrum of physiological changes. Likewise other physiological changes, the immune components and responses are wane as aging is progressing. Immune responses become decline and dysregulating, which is called immunosenescense. Immune components of both innate and adaptive immune response are affected as aging progresses leading to increased vulnerability to infectious diseases. Numbers of immune cells and amounts of soluble immune factors were decreased in aged animal models and human and also functional and structural alterations in immune system were reduced and declined. Cellular intrinsic changes were discovered as well. Recent researches focusing on aging have been enormously growing. Many advanced tools were developed to bisect aging process in multi-directions including immune system area. This review will provide a broad overview of aging-associated changes of key components of immunity.

A Design of Adaptive Controller based on Immune System (면역시스템에 기반한 적응제어기 설계에 관한 연구)

  • Lee Kwon Soon;Lee Young Jin
    • Journal of Institute of Control, Robotics and Systems
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    • v.10 no.12
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    • pp.1137-1147
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    • 2004
  • In this paper, we proposed two types of adaptive control mechanism which is named HIA(Humoral Immune Algorithm) PID and CMIA(Cell-Mediated Immune Algorithm) controller based on biological immune system under engineering point of view. The HIA PID which has real time control scheme is focused on the humoral immunity and the latter which has the self-tuning mechanism is focused on the T-cell regulated immune response. To verify the performance of the proposed controller, some experiments for the control of AGV which is used for the port automation to carry container without human are performed. The experimental results for the control of steering and speed of an AGV system illustrate the effectiveness of the proposed control scheme. Moreover, in that results, proposed controllers have better performance than other conventional PID controller and intelligent control method which is the NN(neural network) PID controller.