• Title/Summary/Keyword: high density lipoprotein-cholesterol

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The Relationship Between Lumbar Spine Bone Mineral Density and Cardiovascular Risk Factors in Premenopausal and Postmenopausal Women (폐경 전후 여성의 요추 골밀도와 심혈관 위험인자와의 연관성)

  • Kim, Mi-Young
    • Journal of radiological science and technology
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    • v.30 no.4
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    • pp.365-371
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    • 2007
  • Recent studies suggest a possible pathogenic linkage between the osteoporosis and atherosclerosis. We investigated the relationship between cardiovascular risk factors, including high sensitivity C-reactive (hs-CRP), hs-CRP and bone metabolism in females. Anthropometric measurements were performed on 300 women, and cardiovascular risk factors, including fasting blood glucose, lipid profiles and hs-CRP. An atherogenic index was calculated using the serum total cholesterol level divided by the high-density lipoprotein cholesterol level. The lumbar spine bone mineral density was measured using dual X-ray abosorptiometry. By bivariate analysis, the lumbar spine BMD showed negative correlations with age, systolic and diastolic blood pressures, serum total cholesterol, high-density lipoprotein cholesterol. The Age, BMI and high-density lipoprotein cholesterol showed significant correlations with the lumbar spine BMD. From linear regression analyses of all the study subjects, age, high-density lipoprotein cholesterol were found to be determinants of the lumbar spine BMD($R^2=0.272$).

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The Effects of Cirsium japonicum on Lipid Profile in Ovariectomized Rats

  • Kwon, Hyeok-Yi;Rhyu, Mee-Ra;Lee, Young-Joo
    • Biomolecules & Therapeutics
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    • v.16 no.3
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    • pp.293-298
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    • 2008
  • Cirsium japonicum water extracts has been used to treat vascular related diseases. We have previously reported that Cirsium japonicum extracts activated estrogen receptors. It is widely known that estrogen increases the high density lipoprotein cholesterol and decrease the low density lipoprotein cholesterol on the lipid profile. But effects of Cirsium japonicum on lipid profile are not reported yet. Therefore, we have studied the effects of Cirsium japonicum on the lipid content in ovariectomized rats. Thirty Sprague-Dawley (SD) rats of $210{\pm}20\;g$ were studied for 10 weeks. The rats were divided into five groups; (I) sham, no ovariectomized rats plus olive oil, (II) ovariectomized rats plus olive oil, (III) ovariectomized rats plus 0.5 mg/kg $17{\beta}$-estradiol (E2) in olive oil, (IV) ovariectomized rats plus 0.5 mg/kg Cirsium japonicum in olive oil, and (V) ovariectomized rats plus 5 mg/kg Cirsium japonicum in olive oil. Treatment with Cirsium japonicum or E2 induced significant reduction in total cholesterol, low density lipoprotein cholesterol/total cholesterol, total cholesterol/high density lipoprotein cholesterol and low density lipoprotein cholesterol/high density lipoprotein cholesterol compared to control group as well as increase in uterine weight. However, changes in triglycerides levels were different. Our results suggest that Cirsium japonicum is functionally similar to E2 in vivo as well as in vitro.

Cholesterol Lowering Effect of Enzymatic Hydrolysates of Squid in Rats

  • Park, Ju-Hyun;Lee, Jung-Eun;Kim, Sang-Moo;Kwak, Hae-Soo
    • Food Science and Biotechnology
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    • v.18 no.6
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    • pp.1541-1544
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    • 2009
  • This study evaluated effects of enzymatic hydrolysates of squid on cholesterol lowering in rats. Thirty male rats were blocked into 3 groups [high cholesterol diet (control), 5% normal squid, and 5% enzymatic hydrolysates of squid] and were raised for 10 weeks. Triglyceride level in enzymatic hydrolysates of squid-fed rats was lower than that in the control. Serum low density lipoprotein-cholesterol level followed in the order of control>normal squid>enzymatic hydrolysates. Serum high density lipoprotein-cholesterol level in enzymatic hydrolysates of squid-fed rats was higher than that in control rats. Liver cholesterol level in enzymatic hydrolysates of squid-fed rats was lower than that in control rats.

A Study of Estrogen only Therapy and Estrogen Plus Androgen Combination Therapy in Surgical Menopause Patients (난소적출술 환자에서 Estrogen 단독요법 및 Estrogen-androgen 병합요법에 관한 연구)

  • Bai, Kwang-Bum
    • Clinical and Experimental Reproductive Medicine
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    • v.29 no.4
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    • pp.279-285
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    • 2002
  • Objective : To evaluate the difference between estrogen only therapy and estrogen-androgen combination therapy in surgical menopause patients. Materials and Method: Surgical menopause patients received 0.625 mg conjugated equine estrogens or 0.625 mg conjugated equine estrogens plus 1.25 mg methyltestosterone for 2 years. Bone mineral density, menopausal symptoms, lipoprotein profiles were measured. Results: Both groups showed increased bone mineral density. In the combination group, total cholestero l, high density lipoprotein cholesterol and triglycerides decreased. In the estrogen only group, low density lipoprotein cholesterol decreased but high density lipoprotein cholesterol increased significantly. In both groups, menopausal symptoms were much improved. Side effects were easily tolerated in both groups. Conclusions: Estrogen-androgen combination therapy had comparable benefits compared with estrogen only therapy.

Relationships among Fasting Serum Insulin, Free Fatty Acid, Lipid Levels and Anthropometric Measurements in Female College Students (여대생의 혈청 인슐린, 유리지방산, 지질 농도와 신체계측치와의 관련성)

  • 김석영
    • Journal of Nutrition and Health
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    • v.32 no.2
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    • pp.189-196
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    • 1999
  • This study was conducted to investigate the relationships among the levels of fasting serum insulin, free fatty acid, lipids and anthropometry in normal-weight female college students. Serum insulin and free fatty acid levels were negatively correlated. However, insulin, triglyceride, and cholesterol levels were not correlated with fat mass or BMI(body mass index). The ability of anthropometric and biochemical indicators to predict fatness could be important for epidemiologic and clinical research. In the subjects, waist cirumference was correlated with BMI, fat mass and percent body fat, and HDLC/CHOL (high density lipoprotein cholesterol/cholesterol)was correlated with body weight, BMI, and fat mass. Our data suggests than waist circumference and HDLC/CHOL are predictors of fatness, whereas WHR apears to be a less important contributor to fatness in female college students.

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Prevalence and risk factors of gallbladder polyps among adults on Jeju Island according to genders (성별에 따른 제주도 성인의 담낭용종 유병률 및 위험인자)

  • Kwon, Oh-Sung;Lee, Sang-Jun;Kim, Young-Kyu;Jung, Jin-Young
    • Proceedings of the Korean Society of Computer Information Conference
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    • pp.333-335
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    • 2021
  • Gallbladder polyps (GBPs) may be a cause of gallbladder cancer. The known risk factors for GBPs are male gender, obesity, metabolic syndrome, and dyslipidemia. Especially, male gender has been known that it strongly affects on the prevalence of GBPs. Therefore, this study aimed to investigate risk factors affecting the prevalence of GBPs among adults on Jeju Island according to genders. We examined 5,574 subjects who visited a single health-screening center in Jeju between January 2015 and December 2019. Univariate and multiple logistic regression analysis were performed to identify risk factors affecting the prevalence of GBPs. The prevalence of GBPs were 8.9% in male subjects and 8.1% in female subjects, respectively. Multivariate analysis revealed that ≥60 year age (odds ratio [OR] 0.659; P=0.027) and aspartate aminotransferase >32 IU/L (OR 0.658; P=0.009) in male subjects and high-density lipoprotein-cholesterol ≥60 mg/dL (OR 0.514; P=0.013) in female subjects were independent factors affecting the prevalence of GBPs. The prevalence of GBPs in men (8.9%) is comparable to that in women (8.1%) on Jeju Island. Age <60 years and the high level of aspartate aminotransferase in men and the greater level of high-density lipoprotein-cholesterol in women were independent risk factors of GBPs on Jeju Island.

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The Affecting Factors of Metabolic Syndrome in Korean Adults in Their 30s and 40s (삼사십대 성인에서 대사증후군 관련 영향 요인)

  • Lee, Hyun-Mee;Kam, Sin;Jin, Soo-Hee
    • The Korean Journal of Health Service Management
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    • v.12 no.3
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    • pp.143-156
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    • 2018
  • Objectives: The aim of this study was to determine the affecting factors of metabolic syndrome (MetS) and it's components in Korean adults in their 30s and 40s. Methods: The present study assessed 1,215 subjects who participated in the Korea National Health and Nutrition Examination Survey in 2014. We analyzed the prevalence rate of MetS and it's components and their affecting factors. Results: The prevalence rate of MetS was 16%. Family history of diabetes mellitus and, low or high saturated fat intake were associated with MetS in males. Low income, low education, excessive sleep, excessive carbohydrate and low saturated fat intake were associated with MetS in females. Triglycerides showed the highest prevalence in males and were related to white collar socioeconomic status, smoking, and obesity. Triglycerides and high-density lipoprotein cholesterol were high in females, and triglycerides were affected by excessive sleep, family history, low saturated fat intake, and obesity. High-density lipoprotein cholesterol was affected by obesity. Conclusions: Because sex differences exist in MetS, it is necessary to intervene through diverse approaches. In particular, a continuous management and preventive intervention for obesity is needed.

Effect of Dynamic Yoga on Body Composition and Blood Lipids in Middle-aged Post-menopausal Women (8주간의 다이나믹 요가가 폐경기 중년여성의 신체조성과 혈중지질에 미치는 영향)

  • Kim, Mi-Sook;Park, Tae-Gon;Kim, Jae-Ho;Lee, Eun-Nam
    • Journal of muscle and joint health
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    • v.15 no.2
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    • pp.166-174
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    • 2008
  • Purpose: The purpose of this study was to examine the effect of a 8-week dynamic yoga program on body composition and blood lipids in middle-aged post-menopausal women. Method: Twenty participants were allocated to the yoga group (YG, n=10) or the control group (CG, n=10). They were assessed for lean body mass, percent body fat, waist to hip ratio, total cholesterol, low density lipoprotein cholesterol, high density lipoprotein cholesterol, and triglyceride both before and after intervention. The yoga group participated in the program lasting $50{\sim}60$ minutes, five times a week for 8 weeks. Results: Unlike the control group, the yoga group showed a significant decrease in total cholesterol, low density lipoprotein cholesterol, percent body fat, and waist hip ratio after the yoga training. However, changes in lean body mass, high density lipoprotein cholesterol, and triglyceride level during the intervention period were not different between the yoga group and the control group. Conclusion: The 8-week dynamic yoga program could be adopted to prevent cardiovascular diseases in middle-aged post-menopausal women by promoting body composition & blood lipids.

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The Effects of Aquatic Exercise Program on Risk Factors of Metabolic Syndrome and Stress in Women (수중운동 프로그램이 성인여성의 대사증후군 위험요소와 스트레스에 미치는 효과)

  • Kim, Ji Young;Kim, Jong Im
    • Journal of muscle and joint health
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    • v.25 no.2
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    • pp.75-83
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    • 2018
  • Purpose: The purpose of this study is to investigate the effects of an 8-week aquatic exercise program on risk factors of metabolic syndrome and stress in women. Methods: This study employed a non-equivalent control group pretest-posttest design. A total of 35 patients were recruited through a community health center. The data were analyzed with the SPSS 22.0 version program, and the outcome variables were risk factors of metabolic syndrome including abdominal circumference, triglyceride, high density lipoprotein cholesterol, blood pressure, fasting blood glucose, and the level of stress. Results: There was no statistically significant differences in abdominal circumference, triglyceride, high density lipoprotein cholesterol, and blood pressure difference (post-pre) between the experimental and control group. However, there was a significant difference in the stress level. Conclusion: This study result support the beneficial effect of stress management in women on risk reduction for metabolic syndrome. Health professionals consider to develop strategy of the aquatic exercise program to reduce factors of metabolic syndrome.

Systematic Literature Review and Meta-Analysis on the Effect of Exercise Intervention Programs on Blood Lipids in Obese Adolescents in Korea according to Sex (국내 비만 청소년을 대상으로 실시한 운동 중재 프로그램의 혈중지질 효과에 대한 체계적 문헌고찰과 메타분석: 성별 차이 분석)

  • Kim, Juri;Lee, Mikyoung
    • Journal of the Korean Society of School Health
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    • v.34 no.2
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    • pp.87-97
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    • 2021
  • Purpose: The authors used a meta-analysis approach to investigate the effects of exercise on gender-specific triglyceride (TG) and high-density lipoprotein cholesterol (HDL-C) in obese adolescents. Methods: This study is a systematic review and meta-analysis study to confirm the effect of exercise intervention according to gender for obese adolescents. PICO were obese a adolescents, exercise intervention, comparative intervention (control and general group),TG and HDL-C. Results: The group of obese male adolescents showed a statistically significant decrease of 51.72 in TG (n=175, MD=-51.72; 95% CI -52.44 to -51.00).There was a statistically significant increase of 4.44 in HDL-C (n=175, MD=4.44; 95% CI 3.79 to 5.10) in the group of obese male adolescents. Conclusion: Triglyceride and high-density lipoprotein cholesterol were analyzed to determine the effect of exercise interventions in obese adolescents according to gender differences. The results of this study can be used as basic data for the design of future exercise intervention studies, subjects, exercise methods, and intervention periods.