• Title, Summary, Keyword: head and neck cancer

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The Effect of Neutron Therapy on Head and Neck Cancer (두경부암(頭頸部癌)에서 중성자선(中性子線) 치료(治療)의 효과(?果))

  • Yoo Seong-Yul;Koh Kyoung-Hwan;Cho Chul-Ku
    • Korean Journal of Head & Neck Oncology
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    • v.5 no.1
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    • pp.31-38
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    • 1989
  • The result of neutron therapy on head and neck cancer using KCCH -Cyclotron neutron which had been using from October 1986 to September 1989 in the Korea Cancer Center Hospital. Among the total of 27 patients the cases of malignant salivary gland tumor were 14 and the cases of advanced head and neck cancer of AJCC stage IV were 13. The local control rate was 80% in malignant salivary gland tumor and 46.2% in advanced head and neck cancer. The 2 year survival rate was 60% in malignant salivary gland tumor and 38.5% in advanced head and neck cancer. Although there was no significant difference in prognosis according to the pathologic types, squamous cell carcinoma revealed a pattern of poor prognosis. The major complication from the neutron therapy had developed 7.1% in malignant salivary gland tumor and 23.1% in advanced head and neck cancer. In conclusion, neutron therapy is superior in the treatment of malignant salivary gland tumor and also effective in the treatment of advanced head and neck cancer when it can avoid to treat some site of low tolerance.

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Can Head and Neck Cancers Be Detected with Mean Platelet Volume?

  • Eryilmaz, Aylin;Basal, Yesim;Omurlu, Imran Kurt
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.16
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    • pp.7045-7047
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    • 2015
  • Background: Mean platelet volume (MPV) is a marker which has been investigated in many cancers but data for head and neck lesions are limited. We aimed to study the MPV levels in head and neck cancers as a diagnostic marker. Materials and Methods: A total of 96 head and neck cancer patients and 31 control patients who did not meet exclusion criteria were enrolled in the study. The cancer locations, the platelet and MPV levels at the first diagnosis time were collected. Results: The head and neck cancer location distribution between these patients was 2 (2.1%) buccal, 9 (9.4%) tongue, 6 (6.3) lip, 1 (1%) gingiva, 1 (1%) hypopharynx, 1 (1%) ear, 58 (60.4%) larynx, 2 (2.1%) maxilla, 2 (2.1%) nasal, 1 (1%) nasopharynx, 2 (2.1%) palatal, 3 (3.1%) primary unknown, 1 (1%) retromolar, 1 (1%) thyroid, 2 (2.1%) tonsil, and 4 (4.2%) salivary gland. MPV levels were significantly different between cancer and control group (p=0.002). The cut-off point for MPV predicting head and neck cancer is >10 fL (sensitivity=55.21, specificity=87.10). Conclusions: MPV level increase, a readily assessable parameter which does not bring extra costs can warn us regarding head and neck cancer risk.

A Pilot Study on Factors Associated with Presentation Delay in Patients Affected with Head and Neck Cancers

  • Baishya, Nizara;Das, Ashok Kumar;Krishnatreya, Manigreeva;Das, Anupam;Das, Kishore;Kataki, Amal Chandra;Nandy, Pintu
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.11
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    • pp.4715-4718
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    • 2015
  • Background: Patient delay can contribute to a poor outcome in the management of head and neck cancers (HNC). The main objective of the present study was to investigate the factors associated with patient delay in our population. Materials and Methods: Patients with cancers of the head and neck attending a regional cancer center of North East India were consecutively interviewed during the period from June 2014 to November 2014. The participation of patients was voluntary. The questionnaire included information on age, gender, residential status, educational qualification, monthly family income, any family history of cancer, and history of prior awareness on cancer from television (TV) program and awareness program. Results: Of 311 (n) patients, with an age range of 14-88 years (mean 55.4 years), 81.7% were males and 18.3% females (M:F=4.4). The overall median delay was 90 days (range=7 days-365 days), in illiterate patients the median delay was 90 days and 60 days in literate patients (P=0.002), the median delay in patients who had watched cancer awareness program on TV was 60 days and in patients who were unaware about cancer information from TV program had a median delay of 90 days (p=0.00021) and delay of <10 weeks was seen in 139 (44.6%) patients, a delay of 10-20 weeks in 98 (31.5%) patients, and a delay of 20-30 weeks in 63 (20.2%) patients. Conclusions: Education and awareness had a significant impact in reduction of median patient delay in our HNC cases.

Diagnosis and Clinical Staging of Head and Neck Cancer (두경부암의 진단과 임상적 병기분류)

  • Park Cheong-Soo
    • Korean Journal of Head & Neck Oncology
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    • v.3 no.1
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    • pp.5-13
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    • 1987
  • Cancer of the head and neck is an uncommon disease accounting for 5 % of all cancers. In an anatomic area so readily visible and palpable for examination without special and expensive diagnositic tools, it is unfortunate that many patients still present with advanced diseases. Since the prognosis is so intimately related to stage of disease, it is very important to detect the earliest stage of cancer with a complete head and neck examination. In the evaluation of cancer at any anatomic site, the description of the extent of the lesion is important. Not only does proper staging of the tumor lead to make decision of the most appropriate treatment, it also serves as a guide for the results of treatment. Proper staging demands a careful clinical assesment of the extent of the cancer. The current staging system for head and neck cancer uses the TNM system devised by American Joint Committee for Cancer Staging and End Result Reporting. T represent the primary tumor, N, regional nodal metastases, and M, distant metastases. The detection, diagnosis, and appropriate treatment of eary cancer will result in improved survival.

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Family History of Cancer and Head and Neck Cancer Risk in a Chinese Population

  • Huang, Yu-Hui Jenny;Lee, Yuan-Chin Amy;Li, Qian;Chen, Chien-Jen;Hsu, Wan-Lun;Lou, Pen-Jen;Zhu, Cairong;Pan, Jian;Shen, Hongbing;Ma, Hongxia;Cai, Lin;He, Baochang;Wang, Yu;Zhou, Xiaoyan;Ji, Qinghai;Zhou, Baosen;Wu, Wei;Ma, Jie;Boffetta, Paolo;Zhang, Zuo-Feng;Dai, Min;Hashibe, Mia
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.17
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    • pp.8003-8008
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    • 2015
  • Background: The aim of this study was to investigate whether family history of cancer is associated with head and neck cancer risk in a Chinese population. Materials and Methods: This case-control study included 921 cases and 806 controls. Recruitment was from December 2010 to January 2015 in eight centers in East Asia. Controls were matched to cases with reference to sex, 5-year age group, ethnicity, and residence area at each of the centers. Results: We observed an increased risk of head and neck cancer due to first degree family history of head and neck cancer, but after adjustment for tobacco smoking, alcohol drinking and betel quid chewing the association was no longer apparent. The adjusted OR were 1.10 (95% CI=0.80-1.50) for family history of tobacco-related cancer and 0.96 (95%CI=0.75-1.24) for family history of any cancer with adjustment for tobacco, betel quid and alcohol habits. The ORs for having a first-degree relative with HNC were higher in all tobacco/alcohol subgroups. Conclusions: We did not observe a strong association between family history of head and neck cancer and head and neck cancer risk after taking into account lifestyle factors. Our study suggests that an increased risk due to family history of head and neck cancer may be due to shared risk factors. Further studies may be needed to assess the lifestyle factors of the relatives.

Guidelines for the Surgical Management of Laryngeal Cancer: Korean Society of Thyroid-Head and Neck Surgery

  • Ahn, Soon-Hyun;Hong, Hyun Jun;Kwon, Soon Young;Kwon, Kee Hwan;Roh, Jong-Lyel;Ryu, Junsun;Park, Jun Hee;Baek, Seung-Kuk;Lee, Guk Haeng;Lee, Sei Young;Lee, Jin Choon;Chung, Man Ki;Joo, Young Hoon;Ji, Yong Bae;Hah, Jeong Hun;Kwon, Minsu;Park, Young Min;Song, Chang Myeon;Shin, Sung-Chan;Ryu, Chang Hwan;Lee, Doh Young;Lee, Young Chan;Chang, Jae Won;Jeong, Ha Min;Cho, Jae-Keun;Cha, Wonjae;Chun, Byung Joon;Choi, Ik Joon;Choi, Hyo Geun;Lee, Kang Dae
    • Clinical and Experimental Otorhinolaryngology
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    • v.10 no.1
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    • pp.1-43
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    • 2017
  • Korean Society of Thyroid-Head and Neck Surgery appointed a Task Force to develop clinical practice guidelines for the surgical treatment of laryngeal cancer. This Task Force conducted a systematic search of the EMBASE, MEDLINE, Cochrane Library, and KoreaMed databases to identify relevant articles, using search terms selected according to the key questions. Evidence-based recommendations were then created on the basis of these articles. An external expert review and Delphi questionnaire were applied to reach consensus regarding the recommendations. The resulting guidelines focus on the surgical treatment of laryngeal cancer with the assumption that surgery is the selected treatment modality after a multidisciplinary discussion in any context. These guidelines do not, therefore, address non-surgical treatment such as radiation therapy or chemotherapy. The committee developed 62 evidence-based recommendations in 32 categories intended to assist clinicians during management of patients with laryngeal cancer and patients with laryngeal cancer, and counselors and health policy-makers.

Pharyngocutaneous Fistula which Occurred During Postoperative Radiotherapy in Larynx Cancer Patient with Dementia (치매가 있는 후두암 환자에서 술 후 방사선치료 중 발생한 인두피부누공)

  • Kim, Jung Jun;Kang, Ju Yong;Choi, Ik Joon;Lee, Myung-Chul
    • Korean Journal of Head & Neck Oncology
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    • v.35 no.2
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    • pp.51-55
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    • 2019
  • Pharyngocutaneous fistula is a relatively common, but serious complication after pharyngeal or laryngeal cancer surgery. It can cause wound infection, longer hospitalization period and sometimes carotid artery rupture which can be fatal. Recently, we experienced a 63-year-old larynx cancer patient who had dementia and alcoholic liver cirrhosis for underlying diseases. He underwent total laryngectomy and both neck dissection, and pharyngocutaneous fistula occurred during postoperative radiotherapy. Pharyngocutaneous fistula during postoperative radiotherapy has not yet reported in the literature, and there are few reports about pre and postoperative management of dementia patient after head and neck cancer surgery. Therefore, we report this case with a brief review of literature.

A Case of Tumor Recurrence at the Tracheotomy Site in Tonsil Cancer Patient (편도암 치료 후 기관절개 부위에서 재발한 1예)

  • Baek, Seung Jae;Park, Yoon Ah;Lee, Jae Woo;Lee, Young Sub;Bong, Jeong Pyo
    • Korean Journal of Head & Neck Oncology
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    • v.32 no.1
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    • pp.21-23
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    • 2016
  • The aim of this report was to present a rare case of a tracheotomy site recurrence after operation and post-operative radiotherapy in head and neck squamous cell carcinoma patient. Tracheotomy site recurrence other than subglottic cancer is very rare in head and neck cancer patient. The granulation tissue around tracheotomy was a fertile "soil" for tumor cell implantation. Midline mucosal sparing block which was used to decreased acute toxicity during post-operative radiotherapy could be facilitating the tumor cell implantation. The head and neck surgeon should try every effort to reduce contamination of cancer cells during operation and consider the entire operative field should be included in post-operative radiation portals.