• Title, Summary, Keyword: functional dyspepsia

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Comparative Study of Acute Dyspepsia, Functional Dyspepsia, Organic Dyspepsia by HRV(Heart Rate Variability) (심박변이도를 통한 급성, 기능성, 기질성 소화불량증의 비교연구)

  • Kim, Hyo-Jin;Kim, Bo-Kyung;Kim, Won-Il
    • Journal of Oriental Neuropsychiatry
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    • v.21 no.2
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    • pp.75-85
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    • 2010
  • Objectives : This study was designed to evaluate the correlation between patterns of dyspepsia(acute dyspepsia, functional dyspepsia, dyspepsia with the organic disease) and autonomic nerve system dysfunction using HRV analysis. Methods : The patient group consisted of 88 patients diagnosed as a dyspepsia (Acute dyspepsia group-35 patients, Functional dyspepsia group-28 patients, Dyspepsia with the organic disease group-28 patients) who visited in the Oriental Medical Hospital of Dong-eui University from 2005.3.OO to 2008.8.OO. And the control group consisted of 33 patients diagnosed as a normal state of stomach during the same period. We checked HRV of the 4 groups over 5 minutes and compared the HRV index between groups. Results : 1. HF, LF, VLF and TP were significantly lower in the acute dyspepsia, functional dyspepsia and organic dyspepsia patient group than in the control group. 2. HF, LF, VLF and TP were higher in the acute dyspepsia patient group than in the organic dyspepsia patient group, but the differences were not statistically significant. 3. HF, LF, VLF and TP were higher in the acute dyspepsia patient group than in the functional dyspepsia patient group, but the differences were not statistically significant. 4. HF, LF, VLF and TP were lower in the functional dyspepsia patient group than in the organic dyspepsia patient group, but the differences were not statistically significant. Conclusions : Compared to the control group, all of the dyspepsia patient groups showed the tendency that the overall activity of the autonomic nervous system and the activity of sympathetic nerves decreased. Although there was no significant difference in the suppression of the autonomic nervous system, chronic dyspepsia patient group was lower than acute dyspepsia patient group, functional dyspepsia patient group was lower than the organic dyspepsia patient group in HRV.

The Effects of Interferential Current Therapy on Functional Dyspepsia

  • Koo, Ja Pung;Shin, Hee Joon;Kim, Nyeon Jun;Jeon, Hye Mi;Park, Joo Hyun;Yun, Young Dae;Lee, Joon Hee;Lim, Sang Wan;Um, Ki Mai;Kim, Ji Sung
    • Journal of International Academy of Physical Therapy Research
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    • v.4 no.1
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    • pp.499-504
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    • 2013
  • This study aims to address the effect of interferential current therapy and thereby to provide basic resources to physical therapies for internal medicine by identifying symptoms for functional dyspepsia and serum gastrin level that shows gastric motility. Following results were obtained by performing interferential current therapy to 16 subjects composed of 8 for functional dyspepsia group and 8 for control group for 20 minutes a day, 3 days a week, for 6 weeks. In control group, serum gastrin level was significantly( p<.01), lowered after the therapy whereas there was no significant difference observed in all questions from questionnaire for symptoms of functional dyspepsia between before and after the therapy. In functional dyspepsia group, serum gastrin level was significantly(p<.01), lowered after the therapy and there was also significant(p<.01) reduction in every question from questionnaire for symptoms of functional dyspepsia between before and after the therapy. There was more significant decrease in serum gastrin level and reduction in questionnaire for symptoms of functional dyspepsia in the functional dyspepsia group compared to the control group(p<.01). This study confirms the interferential current therapy as an effective therapeutic method for internal diseases including functional dyspepsia since it not only improves the symptoms of functional dyspepsia but also allows the gastric motility close to normal.

A Case Report of Functional Dyspepsia with Abdominal Distention (기능성 소화불량증으로 복부창만(腹部脹滿)이 지속되는 환아 증례 1례 보고)

  • Kim, Cho-Young;Chang, Gyu-Tae
    • The Journal of Pediatrics of Korean Medicine
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    • v.23 no.3
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    • pp.121-131
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    • 2009
  • Objectives This study is to report a case that has an important meaning as a result of treating functional dyspepsia with oriental treatment. We investigated functional dyspepsia in 6 years child who had to continue abdominal distention for a month after gastroenteritis. The child has recovered from all dyspepsia symptoms after treating with oriental medicine. Methods The patient had dyspepsia symptoms all day, especially repeated abdominal distention. He sometimes had nausea, vomiting, diarrhea, abdominal pain. For those symptoms, we treated him with herbal medicine and acupuncture. The aim of treatment was to improve functional dyspepsia without western treatment. We measured patient's abdomen circumference for change of abdominal distention. Results The symptoms of functional dyspepsia were vanished and the patient maintains his condition with oriental medicine treatment without western treatment. After herb medicine treatment and acupuncture treatment the patient's dyspepsia symptoms (nausea, vomiting, diarrhea, abdominal pain, and abdominal distention) were vanished and maintained his condition for two months after complete the treatment. Conclusions This study showed that oriental medicine can elevate the functional dyspepsia children's quality of life with continuous health care and treatment. For more accurate studies, further studies would be needed with more cases.

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Analytic Study of 68 Patients with Functional Dyspepsia According to Syndrome Differentiation (68명의 기능성 소화불량증 환자에 대한 한의학적 변증분석)

  • Park, Yang-Chun;Cho, Jung-Hyo;Choi, Sun-Mi;Son, Chang-Gue
    • The Journal of Internal Korean Medicine
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    • v.29 no.3
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    • pp.574-581
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    • 2008
  • Objective : Functional dyspepsia is a common disease impeding subjective quality of life. The present study aimed to analyze syndrome differentiation of functional dyspepsia to help with development of oriental therapeutics. Methods : Sixty-eight subjects diagnosed with functional dyspepsia were analyzed and classified into one of five syndrome differentiations. We compared symptomatic characteristics according to the Nepean Dyspepsia Index (NDI), such as severity, kinds of dyspepsia-related complaints and functional dyspepsia quality of life (QOL) among groups. Results : Patients with disharmony between liver and stomach were most prevalent (52.9%), but no patients with complex of fever and cold. The scores of symptom severity and QOL were not significantly different between groups. Each group had a specified pattern of complaints. Conclusions : Clinical-study based analysis of functional dyspepsia constructed by this study, could be useful in objectively developing Oriental medicines for this disease.

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Effectiveness of Abdominal Manipulation Therapy in Functional Dyspepsia Patients (기능성 소화불량증 환자에 대한 복부(腹部) 수기치료의 효과)

  • Maeng, Tae-Ho;Lee, Jong-Soo
    • Journal of Korean Medicine Rehabilitation
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    • v.25 no.4
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    • pp.113-121
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    • 2015
  • Objectives Functional dyspepsia is a type of disease characterized by bothersome postprandial fullness, early satiation, epigastric pain and burning without structural gastrointestinal disorders. The aim of this study was to evaluate changes in symptoms, quality of life, HRV (Heart Rate Variability) before and after abdominal manipulation therapy in functional dyspepsia patients. Methods We recruited twenty functional dyspepsia patients from the volunteers who applied for this clinical trial. State of Patients were assessed by NDI-K (Nepean Dyspepsia Index Korean Version), HRV (Heart Rate Variability) before treatment. After 4 times of abdominal manipulation therapy for 2 weeks, state of patients were assessed by the same methods. Results Total symptom score and total quality of life score of NDI-K were significantly improved by the abdominal manipulation therapy. After the treatment, the number of subjects within normal range of LF/HF ratio was significantly increased. Although the median of LF/HF ratio did not significantly changed, interquartile range was reduced. Conclusions Abdominal manipulation therapy possibly can be an effective treatment for functional dyspepsia patients, but further studies are needed to demonstrate the effectiveness of abdominal manipulation therapy for functional dyspepsia patients.

Clinical Observation of Changes in Subjective Evaluation Index and Electrogastrography Parameters of Patients with Functional Dyspepsia before and after Oriental Medical Interventions (기능성 소화불량 환자의 한방치료 전후의 주관적 평가지표와 Electrogastrography Parameters를 이용한 객관적 지표의 변화 관찰)

  • Han, Ga-Jin;Kim, Jin-Sung;Ryu, Bong-Ha
    • The Journal of Internal Korean Medicine
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    • v.32 no.4
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    • pp.584-598
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    • 2011
  • Objectives : Functional dyspepsia is a type of disease characterized by bothersome postprandial fullness, early satiation, epigastric pain and burning without structural gastrointestinal disease. The aim of this study was to analyze the characteristics of functional dyspepsia patients and evaluate changes in symptoms, quality of life, and electrogastrography parameters before and after oriental medical interventions. Methods : We recruited forty-six functional dyspepsia patients who visited gastroenterology clinic in the oriental medicine hospital of Kyung Hee University between November 2009 and February 2011. Patients were assessed for their frequency of dyspepsia (based on short form-Leeds Dyspepsia Questionnaire: SF-LDQ), quality of life (based on functional dyspepsia-related quality of life questionnaire: FD-QoL), gastric motility (based on electrogastrography: EGG) on the first visit. Then, the effect of oriental medical interventions was evaluated using EGG on the second visit. Results : The majority of patients had symptoms of nausea and indigestion. The largest decrease in EGG parameters was found in the indigestion group. The frequency of regurgitation and postprandial EGG power % bradygastria showed a significant correlation. Also, significant correlations were found between some items of FD-QoL and some EGG parameters. Compared to the EGG parameters before oriental medical interventions, some parameters after treatment had positive results, implying the improvement of gastric motility disorder. We also found improvement of EGG parameters in both digestant medicinal group and digestant combined with qi-tonifying medicinal group. Conclusions : The results of this study suggest that clinical application of EGG can be an objective diagnostic tool in functional dyspepsia patients visiting oriental medical hospital.

Effect of Herb Medicine Treatment for Functional Dyspepsia: A Randomized Placebo-Controlled and Compared Standard Treatment Trial (기능성 소화불량증 환자에 대한 한약복합제의 치료 효과: 무작위배정 표준치료제 위약 대조군 연구)

  • Kim, Yeon-Mi;Park, Yang-Chun;Jo, Jeong-Hyo;Kang, Wee-Chang;Son, Mi-Won;Hong, Kwon-Eui
    • The Journal of Korean Medicine
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    • v.31 no.1
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    • pp.1-13
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    • 2010
  • Objective: Functional dyspepsia is a prevalent disease. It impedes subjective quality of life. The purpose of this study was to examine the equivalent effect of herb medicine treatment (DA-9701) for functional dyspepsia. Methods: In this randomized, single-blinded, placebo-controlled study, we compared a herb medicine (DA-9701) with standard treatment (mosapride) and placebo for the treatment of functional dyspepsia. 42 volunteers who satisfied the requirements were enrolled in study. Severity of dyspepsia was measured by Nepean Dyspepsia Index (NDI) and Functional Dyspepsia Quality of Life (FD-QOL) before and after treatments. Results: 1. In the DA-9701 group, total key symptoms score was significantly lower and improve rate of key symptoms was higher than in the mosapride and placebo groups, but there were no statistically significant differences between three groups. 2. In the DA-9701 and mosapride groups, "nausea" and "bad breath" were significantly lower compared with the placebo group. 3. In the DA-9701 group, NDI Quality of Life scores were significantly higher, but there were no [other] statistically significant differences between the three groups. 4. In the DA-9701 and mosapride groups, FD-QOL scores were higher compared with the placebo group, but there were no statistically significant differences between the three groups. Conclusion: Herb medicine treatment (DA-9701) is effective to improve the symptoms and quality of life in patients with functional dyspepsia.

The Relationship between Functional Dyspepsia and Dyspepsia caused by Organic Disease in Heart Rate Variability (심박변이도(HRV)에서 기능성 소화불량증과 기질성 소화불량증의 상관성 연구)

  • Kim, Sang-Heon;Kim, Hyo-Jin;Lee, Soo-Jung;Sin, Cheol-Kyung;Lee, Sang-Hee;Kim, Won-Il
    • The Journal of Internal Korean Medicine
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    • v.29 no.2
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    • pp.443-455
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    • 2008
  • Objectives : This study was designed to research whether HRV can yield a suitable diagnosis for activity of autonomic nerve system on functional dyspepsia. Methods : The testing of HRV was carried out at the Oriental Medical Center of Dong-Eui University with the participation of 28 functional dyspepsia patients, 25 dyspepsia caused by organic disease patients and 33 control group people. We checked HRV of the three groups for 5 minutes and compared HRV index(frequency domain analysis: HF, LF, VLF, LF/HF Ratio, TP) between groups. Results were as follows : 1. In the frequency domain analysis, HF, LF, VLF, and TP were significantly lower than the control group in the functional dyspepsia patients and dyspepsia caused by organic disease groups. HF, LF, VLF, LF/HF ratio, and TP were not significantly different between functional dyspepsia group and dyspepsia caused by organic disease group. 2. Age in dyspepsia patient group was significantly higher than in the control group. 3. In the frequency domain analysis, LF, VLF, and TP were significantly lower in the functional dyspepsia group than the control group in age 20-30 years. HF, LF, VLF, LF/HF ratio, and TP were not significantly different between the control group and dyspepsia caused by organic disease group in ages 20-30 years. HF, LF, VLF, LF/HF ratio, and TP were not significantly different between functional dyspepsia group and dyspepsia caused by organic disease group in age 20-30 years. Conclusion : According to this study, autonomic nerve system and parasympathetic nerve system decreased more in the functional dyspepsia patient group compared with the control group.

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Clinical Case Report of Functional Dyspepsia with Gyejibanhasaenggang-tang, Acupuncture, and Moxibustion (계지반하생강탕 및 침구치료로 호전된 기능성 소화불량 환자의 치험 1례)

  • Kim, Sang-jin;Lee, Jae-hong;Ko, Seok-jae;Park, Jae-woo
    • The Journal of Internal Korean Medicine
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    • v.37 no.2
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    • pp.406-411
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    • 2016
  • Objective: This case presents the effects of Gyejibanhasaenggang-tang, acupuncture, and moxibustion on functional dyspepsia.Method: A patient was treated with herbal medicine, acupuncture, and moxibustion. Functional dyspepsia-related quality of life (FD-QoL), the gastrointestinal symptom rating scale (GSRS), and the gastrointestinal scale (GIS) were assessed for evaluation.Results: Symptoms of functional dyspepsia improved after the 22 days of Gyejibanhasaenggang-tang treatment.Conclusion: This case suggests that the combination of Gyejibanhasaenggang-tang, acupuncture, and moxibustion could be effective in treating functional dyspepsia.

Investigation on evaluation of functional dyspepsia by using Digital Infrared Thermal Images (기능성 소화불량증에 대한 적외선 체열검사(DITI)의 임상 지표적 의의 연구)

  • Jeong, Seung-Hwan;Im, In-Hwan;Um, Eun-Jin;Lee, Beom-Jun;Na, Byong-Jo
    • Journal of Oriental Medical Thermology
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    • v.6 no.1
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    • pp.56-62
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    • 2008
  • Objective: To investigate the significance of temperature differences on two different acupuncture points between functional dyspepsia(FD) group and non-functional dyspepsia(non-FD) group respectively. Methods: We performed this research on 40 patients who came and took D.I.T.I in Kang-nam korean hospital kyung-hee university. We analyzed the averaged temperature of Zhongwon(CV12), Indang(HN1) and, also, investigated the significance of subtraction from Indang to Zhongwon temperature statistically. Results: The temperature differences from Indang to Zhongwon between functional dyspepsia group and non-functional dyspepsia group was significant, it meant that patients who have functional dyspepsia have more significant temperature difference from Indang(HN1) to Zhongwon(CV12). The direct comparisons of mean temperature between Indang and Zhongwon in the FD group and non-FD group were not significant. Conclusion: The study provide hypothesis on the temperature difference from Indang(HN1) to Zhongwon(CV12) and its association with functional dyspepsia. This study can provide a foundation for future studies on the evaluation of functional dyspepsia by using D.I.T.I.

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