• Title, Summary, Keyword: fine needle aspiration cytology

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Fine Needle Aspiration Cytology of Pulmonary Carcinosarcoma (폐에 발생한 암육종의 세침흡인 세포학적소견 -1 증례보고-)

  • Jang, Tae-Jung;Lee, Kwang-Gil;Hong, Soon-Won
    • The Korean Journal of Cytopathology
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    • v.1 no.2
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    • pp.164-169
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    • 1990
  • Carcinsarcoma is an uncommon pulmonary malignancy characterized by carcinmatous parenchyma and sarcomatous stroma. The cytologic, immunohistochemical and ultrastructural features of a case of pulmonary carcinosarcoma suspected by fine needle aspiration cytology is presented. Only bizarre spindle cells arranged in loose groups, in microtissue fragments and in a dissociate fashion were present on the aspiration smears. They were markedly positive for vimentin. The epithelial component was not found, which was probably due to marked paucity of carcinomatous component that was proved by histologic examination of the resected tumor. The diagnosis of pulmonary carcinosarcoma should be conidered whenever poorly differentiated epithelial ceil groups with a malignant mesenchymal component set in a myxoid background are seen in a pulmonary cytology specimen.

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Fine Needle Aspiration Cytology of Salivary Gland Lesions (타액선병변의 세침흡인 세포검사)

  • Lee, Seung-Sook;Park, In-Ae;Ham, Eui-Keun;Lee, Sang-Kook
    • The Korean Journal of Cytopathology
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    • v.4 no.2
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    • pp.111-120
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    • 1993
  • Fine needle aspiration cytology has become a frequently used technique for the diagnosis of lesions in the head and neck. Fine needle aspiration cytology of the salivary glands were performed on 66 patients. In 59 patients with satisfactory samples, cytologic diagnoses were as follows; there were 47 benign lesions, including pleomorphic adenoma(20), Warthin's tumor(3), benign cystic lesion(4), Inflammatory lesion(4), lymphoid lesion(3), myoepithelioma(1), unspecified benign neoplasm (5), and unclassified benign lesion(7). There were 6 cases of undetermined malignancy and 6 malignant lesions including mucoepidermoid carcinoma(3), adenoid cystic carcinoma(1), carcinoma ex pleomorphic adenoma(1), and metastatic carcinoma(1) in cytologic diagnosis. In 25 patients, the cytologic diagnosis was correlated with histologic findings. The sensitivity of the benign lesion was 96% and the specificity was 82%. There was no false-positive diagnosis. The sensitivity and the specificity of pleomorphic adenoma were 75% and 95%, respectively. Some of Warthin's tumors were confused with benign cystic lesion due to frequent cystic change of the tumor. The sensitivity and specificity of the malignant lesions were 56% and 88%, respectively. There were three false negative diagnoses. Two mucoepidermoid carcinomas were correctly diagnosed by cytology. Two of three adenoid cystic carcinomas were misdiagnosed as benign tumors.

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Fine Needle Aspiration Cytology of Metastatic Nasopharyngeal Undifferentiated Carcinoma of Lymph Node - Report of a Case Presenting Spindle Cell Pattern - (림프절로 전이된 비인두 미분화 암종의 세침흡인 세포학적 소견 -주로 방추형 세포의 양상을 나타낸 1례-)

  • Min, Dong-Won;Lee, Kwang-Gil
    • The Korean Journal of Cytopathology
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    • v.4 no.1
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    • pp.35-40
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    • 1993
  • We describe a case of fine needle aspiration cytology of metastatic nasopharyngeal carcinoma in the lymph node of the neck presenting a predominantly spindle cell pattern. A 36 year-old male patient complained of dysesthesia on the right face and a palpable neck mass. Fine needle aspiration was done on the neck mass. Tumor cells were present in syncytial groups or singly with mainly spindle shaped nuclei, vesicular chromatin, thin and regular nuclear membrane, occasional prominent nucleoli and a few fool of cellular cohesiveness. The cytoplasm was scant and pale with ill-defined borders. Mature lymphocytes were present in the background of aspirates and within the tumor cell clusters. Histologically, the tumor of nasopharynx showed several areas of spindle cell pattern. Because the tumor cells showed a predominantly spindle shape with vesicular nuclear chromatin, the differential diagnosis of spindle cell sarcoma or granuloma of epithelioid clils were considered, but the characteristic morphology of the nuclei with vesicular chromatin and prominent nucleoli, and cellular cohesiveness were important in making the diagnosis of nasopharyngeal carcinoma. The possibility of metastatic carcinoma should always be considered in fine needle aspiration cytology of the lymph node in the neck because the incidence of metastatic carcinoma, particularly of the nasopharyngeal carcinoma in the lymph nodes of the neck is relatively high.

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The Usefulness of Fine Needle Aspiration Cytology of Bone Lesions (골 병변에서 세침흡인 세포검사의 유용성)

  • Kim, Bohng-Hee;Gong, Gyung-Yub
    • The Korean Journal of Cytopathology
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    • v.13 no.2
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    • pp.51-59
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    • 2002
  • To determine the usefulness on fine needle aspiration cytology(FNAC) of bone lesions and the complementary role of FNAC and percutaneous needle biopsy, 75 cases of FNAC taken from bone lesions were analyzed. Correlations with histopathology were possible in 47 cases, including 14 cases of simultaneous core biopsy and 33 cases of subsequent open biopsy due to inadequate aspirates. Among 75 cases, 4 cases were benign tumors and tumor-like lesion, 11 cases were malignant primary bone tumors, 17 cases were metastatic tumors, and 43 cases were nonneoplastic bone lesions. The aspirates were adequate in 35 cases(46.7%), in all of which the discrimination between benignancy and malignancy was possible. The main reason for Inadequate aspirates was due to hypocellularity. In the cases of aspiration and core biopsy simultaneously done, the diagnostic accuracy of aspiration, core biopsy, and both were 57%(8/14), 78.6%(11/14), and 92.9%(13/14), respectively. We conclude that a final diagnosis based on cytology is possible with the adequate aspirates and the clinical and radiological findings. Also we confirm the complementary role between FNAC and core biopsy in bone lesions.

Fine Needle Aspiration Cytology of Medullary Carcinoma of the Breast - A Case Report (유방의 수질암종의 세침흡인 세포학적 소견 - 1예 보고 -)

  • Chun, Yi-Kyeong;Ko, Ill-Hyang
    • The Korean Journal of Cytopathology
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    • v.5 no.1
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    • pp.57-60
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    • 1994
  • Medullary carcinoma (MC) of the breast is an uncommon histologic form of infiltrating ductal carcinoma and the cytologic features of MC are not well delineated. We recently experienced a case of fine needle aspiration cytology of MC of the breast. The characteristic cytopathologic features were cellular aspirate consisting of large, pleomorphic cells in background of many single to clusters of lymphocytes.

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Fine Needle Aspiration Cytology of Mucoepidermoid Carcinoma of the Lung -A case report- (폐에 발생한 점액표피양 암종 -1예 보고-)

  • Hong, Soon-Won;Lee, Kwang-Gil
    • The Korean Journal of Cytopathology
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    • v.1 no.2
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    • pp.170-174
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    • 1990
  • The mucoepidermoid carcinoma is a rare tumor in the lung. A case of bronchial mucoepidermoid carcinoma diagnosed by fine needle aspiration cytology is presented. The smear showed many intermediate cells with occasional mucus-secreting cells. Malignant squamous cells were not present. The cellular arrangement of intermediate cells was overlapping and grouped in ball-like fashion. These cytologic features are unique for diagnosis of this tumor.

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Fine Needle Aspiration Cytology of the Intraductal Papillary Mucinous Tumor of the Pancreas -A Case Report- (췌관내 유두모양점액종양의 세침흡인 세포학적 소견 -1예 보고-)

  • Do, In-Gu;Park, Jae-Hoon;Kim, Youn-Wha;Lee, Ju-Hie;Yang, Moon-Ho;Hong, Sung-Wha;Park, Yong-Koo
    • The Korean Journal of Cytopathology
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    • v.14 no.2
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    • pp.91-95
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    • 2003
  • Intraductal papillary mucinous tumor of the pancreas is characterized by intraductal papillary proliferation of mucin-producing epithelial cells with or without excessive mucin secretion. According to the degree of epithelial dysplasia, intraductal papillary mucinous tumor is classified into adenoma, borderline tumor, and carcinoma. We recently experienced a case of fine needle aspiration cytology of the intraductal papillary mucinous adenoma in a 69-year-old male. The fine needle aspiration cytology yielded flat sheets of columnar, mucin containing epithelial cells in the background of dense mucin containing degenerated cellular material and histiocytes.

Fine Needle Aspiration Cytology of Alveolar Soft Part Sarcoma - A Case Report - (포상연부육종의 세침흡인 세포학적 소견 - 1예 보고 -)

  • Han, Hye-Seung;Park, In-Seo;Han, Jee-Young;Kim, Joon-Mee;Kim, Young-Bae;Hwang, Tae-Sook;Chu, Young-Chae
    • The Korean Journal of Cytopathology
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    • v.11 no.2
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    • pp.115-119
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    • 2000
  • Alveolar soft part sarcoma is a rare soft tissue tumor. Few cases on fine needle aspiration cytology have been reported in the literature. We experienced a case of recurrent alveolar soft part sarcoma of the right thigh diagnosed by fine needle aspiration cytology in a 47-year-old man. Cytologic findings showed single cells and clusters associated with thin wailed vasculature in a distinct pseudo-alveolar pattern. The tumor cells exhibited round or ovoid abundant granular cytoplasm and large pleomorphic nuclei with prominent central nucleoli.

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Fine Needle Aspiration Cytology of Inflammatory Myofibroblastic Tumor in Mesentery - A Case Report - (장간막에서 발생한 염증성 근섬유모세포종의 세침흡인 세포학적 소견 - 1예 보고 -)

  • Son, Hyun-Jin;Kim, Joo-Heon;Moon, Woo-Sung;Choi, Ho-Yeul;Kang, Myoung-Jae
    • The Korean Journal of Cytopathology
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    • v.11 no.1
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    • pp.35-39
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    • 2000
  • Since inflammatory myofibroblastic turner was initially recognized in the lung, this tumor has been described in other extrapulmonary sites. In spite of relatively uniform histologic findings in various organs, a rarity in extrapulmonary sites and highly vascular characteristics frequently lead to a misdiagnosis in preoperative radiology and fine needle aspiration cytology. We present a case of inflammatory myofibroblastic tumor occurring in the mesentery of a 4-month-old girl. Fine needle aspiration cytology smear disclosed characteristic spindle cells intermixed with prominent mature plasma cells and lymphocytes. According to the immunohistochemical staining, we recognized that the intervening spindle cells are myofibroblasts which have reactivity for the both actin and vimentin.

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Fine Needle Aspiration Cytology of Proliferative Fasciitis (증식성 근막염의 세침흡인 세포학적 소견)

  • Choi, Yoon-Jung;Yi, Sang-Yeop;Yang, Woo-Ick;Jung, Soon-Hee;Lee, Kwang-Gil
    • The Korean Journal of Cytopathology
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    • v.4 no.1
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    • pp.52-56
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    • 1993
  • Proliferative fasciitis is a benign pseudosarcomatous mesenchymal lesion occurring in the subcutis. The lesion occurs clinically as a tumorous mass that develops within a rather short time in elderly patients. We recently experiecened a case of fine needle aspiration cytology of proliferative fasciitis in the left anterior chest wall of a 72 year-old male patient. The smear revealed two types of cells. One was the large and mostly oval cell with one or two nuclei lying at the periphery of the cell body and abundant basophilic cytoplasm like the ganglion cell. The nuclei were round to oval, had vesicular chromatin and contained prominent nucleoli. The other was the spindle shaped fibroblast with an oval nucleus. The differential diagnosis includes a true tumor such as ganglioneuroma, rhabdomyosarcoma, and liposarcoma and therefore fine needle aspiration cytology is very much indicated in order to exclude these possibilities.

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