• Title, Summary, Keyword: fine needle aspiration cytology

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Fine Needle Aspiration Cytologic Findings of Thyroid Lymphoma -Report of Two Cases- (갑상선 림프종의 세침흡인 세포학적 소견 -2 예 보고-)

  • Lee, Hye-Kyung;Lee, Jong-Min;Kang, Chang-Suk
    • The Korean Journal of Cytopathology
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    • v.13 no.1
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    • pp.33-37
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    • 2002
  • We report two different types of thyroid lymphoma associated with Hashimoto's thyroiditis. Both showed autoantibodies and were compatible with Hashimoto's thyroiditis according to their clinical backgrounds. A 76-year-old female noted a painless, rapidly growing mass in her neck which was diagnosed as diffuse non-Hodgkin's lymphoma, large cell type, after the fine needle aspiration cytology of the thyroid. She underwent chemo-radiotherapy and is free of the disease 10 months after diagnosis. The other patient, a 73-year-old female with a diffuse golfer, was diagnosed on fine needle aspiration cytology as having Hashimoto's thyroiditis. Three years later she developed a hard nodular growth in the both lobes of the thyroid. This was subjected to fine needle aspiration cytology and needle biopsy and was diagnosed as a MALT lymphoma. She refused any treatment and died 12 months after the diagnosis.

Clinical Application of Ultrasound-Guided Thyroid Fine Needle Aspiration Biopsy and Thinprep Cytology Test in Diagnosis of Thyroid Disease

  • Wei, Ying;Lu, Yao;Li, Chenxi
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.10
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    • pp.4689-4692
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    • 2016
  • Purpose: To study the clinical application value of ultrasound guided thyroid fine needle aspiration biopsy and thinprep cytology testing in diagnosis of thyroid disease. Methods: A total of 78 patients with thyroid nodules were enrolled, 34 males and 44 females, aged 33-64 years old with mean age of 47.6 years. All underwent thyroid module fine needle puncture after surgery to assess cell pathology and histopathological features. Results: Sufficient specimens were obtained from all of 78 patients, the cytological results of 73 cases (93.6 %) being consistent with pathological results. While 20 cases (25.6 %) were malignant tumors, 44 (56.4 %) were benign and 9 (11.5 %) were non-tumor lesions. The sensitivity of benign and malignant thyroid nodule by thyroid fine needle puncture was 90.9 %, specificity was 98.1 % and the positive predictive value was 96.3 %. Conclusions: It is demonstrated that ultrasound-guided thyroid fine needle aspiration biopsy and thinprep cytology testing have diagnostic value in clinical application for thyroid disease,showing good diagnostic coincidence rates with histopathological examination. They can thus be regarded as safe and effective for preoperative diagnosis and providing an appropriate basis for selection of surgery.

Fine Needle Aspiration Cytologic Diagnosis of Thymoma Presenting as a Thyroid Nodule - A Report of Two Cases - (갑상선 종괴로 촉지된 흉선종의 세침흡인 세포학적 진단 - 2예 보고 -)

  • Kim, Dong-Ja;Park, Ji-Young;Kum, Yoon-Seup;Park, Tae-In;Sohn, Yoon-Kyung
    • The Korean Journal of Cytopathology
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    • v.11 no.1
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    • pp.41-45
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    • 2000
  • Thymoma is the most common anterior mediastinal tumor in adults. Rarely, it is presented as the anterior neck mass, commonly located in the anterolateral aspect of the neck or adjacent to the thyroid. We experienced two cases of fine needle aspiration cytology of thymoma, mimicking thyroid mass. The first case was an ectopoic cervical thymoma in a 31-year-old female. The fine needle aspiration cytology was misinterpreted as reactive hyperplasia of lymph node. But the histologic diagnosis was thymoma, predominantly lymphocytic type. The second case was an invasive thymoma in a 66-year-old female, who complained a large anterior neck mass. The fine needle aspiration cytology revealed biphasic population of some clusters of epithelial cells and scattered lymphocytes. The cytologic diagnosis was thymoma and was confirmed as invasive thymoma after the biopsy. Therefore, when the cytologic feature of anterior neck mass shows the both lymphocyte and epithelial component, the differential diagnosis should Include the possibility of thymoma.

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Fine Needle Aspiration Cytologic Findings of Fibromatosis Colli - A Report of Three Cases - (경부섬유종증의 세침흡인 세포소견 - 3예 보고 -)

  • Park, In-Suh;Kim, Lucia;Choi, Suk-Jin;Han, Jee-Young;Chu, Young-Chae;Choi, Sun-Geun;Kim, Joon-Mee
    • The Korean Journal of Cytopathology
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    • v.16 no.1
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    • pp.61-65
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    • 2005
  • Fibromatosis colli is a benign fibrous tissue proliferation of sternocleidomastoid muscle, which is usually observed during the first month of life, often associated with congenital torticollis. It should be differentiated from other neck masses in infants because the usual initial treatment of fibromatosis celli is conservative management and invasive therapy should be avoided. Fine needle aspiration cytology provides an excellent minimally invasive diagnostic way for evaluation of infantile neck masses. We describe three cases of fibromatosis colli diagnosed by fine needle aspiration cytology. All of them were younger than one month and presented as a neck mass. Clinical impressions were malignant tumors in two cases and fibromatosis colli in one case. Fine needle aspiration cytology revealed benign and mature fibroblasts and atrophic striated muscle fibers. The cytologic diagnosis was fibromatosis colli or benign fibous lesion.

Fine Needle Aspipration Cytology of Metastatic Pulmonary Seminoma - A Cese Report - (세침흡인 세포검사로 진단된 폐에 전이한 정상피종 - 1예 보고 -)

  • Jeong, Hwa-Sook;Lee, Geon-Kook;Kim, Wun-Jae;Earm, Jae-Ho;Song, Hyung-Geun
    • The Korean Journal of Cytopathology
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    • v.7 no.1
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    • pp.97-102
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    • 1996
  • Fine needle aspiration cytology of a pulmonary mass was performed on a 51-year-old man who had a left testicular mass. Cytologic features were composed of a homogeneous population of malignant cells associated with a background of foamy and lacelike material. The cellular features were characterized by monomorphous cell proliferation of relatively regular large cells, generally isolated or grouped. Occasionally, fine blanching stroma with large tumor cells and scanty lymphocytes were noted. The tumor cells had a round, regular nucleus, prominent round nucleoli, and a thin rim of cytoplasm containing large vacuoles or lacunae filled with glycogen. The fine needle aspiration cytologic diagnosis was highly consistent with metastatic seminoma from testis and less likely primary or other metastatic carcinoma. The diagnosis of resected testicular mass was classic seminoma. Despite the fact that cytopathologists were not familial with diagnosis of seminoma due to clinician's lack of interest in fine needle aspiration cytology of germ cell tumors including seminoma, it appears that a diagnosis of this tumor should not be problematic in cytologic material if specific histologic criteria are applied.

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Fine Needle Aspiraton Cytology of Polymorphous Low Grade Adenocarcinoma in the Hard Palate - A Case Report - (경구개에 발생한 다형성 저등급 선암종의 세침흡인 세포학적 소견 - 1예 보고 -)

  • Kim, Wan-Seop;Jeon, Seok-Hoon;Hong, Eun-Kyung;Park, Moon-Hyang;Lee, Jung-Dal
    • The Korean Journal of Cytopathology
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    • v.9 no.2
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    • pp.181-185
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    • 1998
  • Polymorphous low grade adenocarcinoma(PLGA) is a rare malignant tumor of the salivary gland. It is characterized by diverse histology, bland-locking cytology indolent behavior and favorable prognosis. The fine needle aspiration cytologic features of PLGA are described. The aspirates from the hard palate in a 33-year-old woman showed cellular smear composed of monotonous small round to oval cells with scanty cytoplasm. Papillary, tubular and cell ball arrangements with characteristic dense stromal spheres were recognized. PLGA could be suggested by fine needle aspiration cytology, if one encountered cellular smear with various architectures and uniform bland-locking cytologic feature.

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Fine Needle Aspiration Cytology of Endodermal Sinus Tumor of the Ovary - A Case Report - (난소 내배엽동 종양의 세침흡인 세포학적 소견 - 1예 보고 -)

  • Kim, Jin-Man;Kang, Dae-Young
    • The Korean Journal of Cytopathology
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    • v.6 no.1
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    • pp.54-57
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    • 1995
  • We report a case of fine needle aspiration cytology of endodermal sinus tumor of the ovary. A 13-year-old girl complained of abdominal mass and pain. The abdominal sonography revealed a well-demarcated huge mass, which was solid and multiseptated. Percutaneous fine needle aspiration was performed from the mass. The smears revealed moderate cellularity, which was arranged in sheets or clumps of pleomorphic malignant cells on mucoid background The valuable characteristic features of tumor cells were papillary configuration, vacuolated cytoplasm and intracellular and extracellular hyaline globules. The diagnosis was confirmed later by histologic study of surgical resection of the specimen.

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Fine Needle Aspiration Cytological Findings of Burkitt lymphoma -A Brief Case Report- (버킷 림프종의 세침흡인 세포소견 -짧은 증례 보고-)

  • Jo, Hyang-Jeong;Oh, Jung-Taek;Kim, Gang-Deuk;Kim, Hun-Soo
    • The Korean Journal of Cytopathology
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    • v.18 no.2
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    • pp.175-177
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    • 2007
  • A case of Burkitt lymphoma diagnosed through fine needle aspiration cytology is described, A 66-year-old man presented with lymphadenopathy on the right cervical neck and axillary area. An ultrasonogram and CT scan for the cervical neck showed a multiple variable sized lymphadenopathy with pericapsular invasion and necrotic foci, Fine needle aspiration cytology (FNAC) of the cervical lymph nodes revealed very cellular and necrotic smears consisting of diffusely scattered intermediate monotonous round cells, tingible body macrophages and many mitotic figures. Histological features of the excised lymph nodes showed the classic morphological features of Burkitt lymphoma. Recognition of the characteristic cytological features can suggest the possibility of Burkitt lymphoma.

Nuclear Morphometry of Fibroadenoma and Carcinoma of Breast - Comparison between fine needle aspiration cytology and biopsy - (유방 섬유선종과 유방암종의 화상 계측에 관한 연구 - 세침 홉인 세포 검사와 조직 검사간의 비교를 중심으로 -)

  • Sohn, Jin-Hee;Choi, Young-Hee;Park, Young-Eui
    • The Korean Journal of Cytopathology
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    • v.9 no.2
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    • pp.161-168
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    • 1998
  • Primary breast lesions diagnosed by fine needle aspiration cytology, confirmed by histologic examination were analyzed by morphometry to evaluate the difference between benign and malignant lesions, and the methods obtaining the sample. four size factors and 5 form factors were evaluated in 22 fibroadenomas and 20 carcinomas by image analyzer(Zeiss Ibas 2000) using the H-E stained slides. Nuclear size was significantly larger in the carcinoma cells than fibroadenoma cells both in the cytology and biopsy specimens, but the form factors were not significantly different. Both fibroadencma and carcinoma cells were significantly larger in cytologic smear than histologic section. The cells in the cytology were more regular and round than those in histology, but not statistically significant. Fibroadenomas having cellular proliferation and atypism exhibited larger size and more irregular nuclei than non-proliferative fibroadenoma, but not statistically significant. Therefore nuclear morphometric analysis can be a helpful method to diagnose the questionable breast lesions and is a method appropriate for use as a quality control procedure in the fine needle aspiration cytology.

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A Case of Hepatoma with Duodenal Metastasis Proved by Liver Aspiration Cytology and Gastrofiberscopic Duodenal Biopsy (십이지장 궤양으로 발현된 전이성 간세포암종 1예)

  • Kim, Sung-Jin;Park, Seok-Gun;Han, Dong-Sun;Kim, Sung-Sook
    • The Korean Journal of Cytopathology
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    • v.2 no.2
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    • pp.105-110
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    • 1991
  • We report a case of hepatoma with duodenal metastasis in a 53 year-old male patient. Hepatoma was confirmed by fine needle aspiration cytology technique, and duodenal metastasis by gastrofiberscopic biopsy. Duodenal metastasis of hepatoma is rare. We briefly review the role of fine needle aspiration cytology technique in diagnosis of hepatoma.

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