• Title, Summary, Keyword: etiologic factors

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Cutis Verticis Gyrata: A Case Report (원발성 뇌회상 피부의 치험례)

  • Park, Sung Hoon;Yang, Ho Jik;Kim, Jong Gu
    • Archives of Plastic Surgery
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    • v.33 no.4
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    • pp.503-505
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    • 2006
  • Purpose: Cutis verticis gyrata(CVG) is a morphologic syndrome, typically occurring on the scalp, characterized by varing development of permanent folds and furrows conferring a corrugated or convoluted appearance which resembles the outer surface of the cerebrum. Cutis verticis gyrata can be categorized into primary and secondary types according to various etiologic factors and associated conditions which cause disease process. Methods: We report a case of essential primary cutis verticis gyrata in a 24-year-old male who did not have any other underlying or associated conditions. Results: After we made an incision to the galea aponeurotica of patient's scalp four times under local anesthesia, we dissected along the subapponeurotic layer and adjusted the flaps each other, and then sutured the flap. Conclusion: After the operation, the clear margin disappeared and it did not recur.

The use of the buccal fat pad flap for oral reconstruction

  • Kim, Min-Keun;Han, Wonil;Kim, Seong-Gon
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.39
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    • pp.5.1-5.9
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    • 2017
  • Many congenital and acquired defects occur in the maxillofacial area. The buccal fat pad flap (BFP) is a simple and reliable flap for the treatment of many of these defects because of its rich blood supply and location, which is close to the location of various intraoral defects. In this article, we have reviewed BFP and the associated anatomical background, surgical techniques, and clinical applications. The surgical procedure is simple and has shown a high success rate in various clinical applications (approximately 90%), including the closure of oroantral fistula, correction of congenital defect, treatment of jaw bone necrosis, and reconstruction of tumor defects. The control of etiologic factors, size of defect, anatomical location of defect, and general condition of patient could influence the prognosis after grafting. In conclusion, BFP is a reliable flap that can be applied to various clinical situations.

Unilateral segmental odontomaxillary hypoplasia: an unusual case report

  • Pandey, Sushma;Pai, Keerthilatha M.;Nayak, Ajay G.;Vineetha, Ravindranath
    • Imaging Science in Dentistry
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    • v.41 no.1
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    • pp.39-42
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    • 2011
  • Facial asymmetry is not an uncommon occurrence in day to day dental practice. It can be caused by various etiologic factors ranging from facial trauma to serious hereditary conditions. Here, we report a rare case of non-syndromic facial asymmetry in a young female, who was born with this condition but was not aware of the progression of asymmetry. No relevant family history was recognized. She was also deficient in both deciduous and permanent teeth in the corresponding region of maxilla. Hence, the cause of this asymmetry was believed to be a segmental odontomaxillary hypoplasia of left maxilla accompanied by agenesis of left maxillary premolars and molars and disuse atrophy of corresponding facial musculature. This report briefly discussed the comparative features of segmental odontomaxillary hypoplasia, hemimaxillofacial dysplasia, and segmental odontomaxillary dysplasia and justified the differences between segmental odontomaxillary hypoplasia and the other two conditions.

A Case Report of Epileptic Children Quitted Taking Anticonvulsant (항경련제 복용을 중단한 특발성 간질 환아 치험 1례)

  • Han, Jae-Kyung;Kim, Yun-Hee;Kim, Yun-Hee
    • The Journal of Pediatrics of Korean Medicine
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    • v.18 no.2
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    • pp.263-271
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    • 2004
  • Objective : Epilepsy is a brain condition which causes a person to suddenly lose consciousness and sometimes to have fits. The etiologic factors of epilepsy are various, but most of cases are idiopathic. The purpose of this study is to report a pediatric patient with idiopathic epilepsy. Method : We treated him with herb medicine, acupucture and anticonvulsant. Then, we stopped administering anticonvulsant, and observed the progress of his condition. Result : We had good effect with oriental medical treatment on an epileptic who quitted taking anticonvulsant. Conclusion : We report the good results of oriental medicine on a pediatric patient with idiopathic epilepsy. And the further study is needed with more cases, longer duration and other tools.

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Reversal of Doxorubicin-induced Cardiotoxicity by Using Phytotherapy: A Review

  • Hosseini, Azar;Sahebkar, Amirhossein
    • Journal of Pharmacopuncture
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    • v.20 no.4
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    • pp.243-256
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    • 2017
  • Doxorubicin as a chemotherapeutic drug is widely used for the treatment of patients with cancer. However, clinical use of this drug is hampered by its cardiotoxicity, which is manifested as electrocardiographic abnormalities, arrhythmias, irreversible degenerative cardiomyopathy and congestive heart failure. The precise mechanisms underlying the cardiotoxicity of doxorubicin are not clear, but impairment of calcium homeostasis, generation of iron complexes, production of oxygen radicals, mitochondrial dysfunction and cell membrane damage have been suggested as potential etiologic factors. Compounds that can neutralize the toxic effect of doxorubicin on cardiac cells without reducing the drug's antitumor activity are needed. In recent years, numerous studies have shown that herbal medicines and bioactive phytochemicals can serve as effective add-on therapies to reduce the cardiotoxic effects of doxorubicin. This review describes different phytochemicals and herbal products that have been shown to counterbalance doxorubicin-induced cardiotoxicity.

Sleep-Disordered Breathing and Metabolic Dysfunction (수면호흡장애와 대사적 기능장애)

  • Joo, Soon-Jae;Shin, Chol
    • Sleep Medicine and Psychophysiology
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    • v.12 no.1
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    • pp.17-22
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    • 2005
  • Sleep-disordered breathing (SDB) is associated with increased cardiovascular and cerebrovascular morbidity. Epidemiological and clinic-based studies have shown that SDB is related to impaired glucose tolerance and increased insulin resistance, independent of obesity. Despite of a consistent association between SDB and impaired glucose-insulin metabolism, the mechanism underlying this relationship has not been fully elucidated. It is recognized that hypoxemia and hypercapnia that occur in SDB provoke sympathetic nervous activity and catecholamine, epinephrine and norepinephrine, and cortisol are released. Sympathetic hyperactivity and increased catecholamines can impair glucose homeostasis by increasing glycogenolysis and gluconeogenesis, which can result in increased circulating insulin levels and increased risk of insulin resistance. A prospective study is needed to investigate the causal relationship between SDB and impaired glucose-insulin metabolism in a healthy population without diabetes, hypertension and obesity as etiologic risk factors.

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A Multi-organ Abscesses Including Brain Caused by a Congenital Pulmonary Arteriovenous Fistula

  • Kim, Hyung-Suk;Sung, Jae-Hoon;Son, Byung-Chul;Lee, Sang-Won
    • Journal of Korean Neurosurgical Society
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    • v.37 no.4
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    • pp.303-306
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    • 2005
  • In cases of brain or other organ abscess, the causative etiology or disease are not always definable. We report a case of brain, renal, and possibly lung abscesses in a middle aged woman. After close, stepwise surveillance of possible etiologic factors, we covered out a small solitary pulmonary arteriovenous fistula without any pulmonary symptoms and successfully occluded the fistula via endovascular approach. The congenital pulmonary arteriovenous fistula should be bear in mind as a cause of repeated, multiple systemic infective source spray and be pursued despite of negative initial baseline studies.

Bisphosphonate-related osteonecrosis of the jaw in a multiple myeloma patient: A case report with characteristic radiographic features

  • Lee, Byung-Do;Park, Moo-Rim;Kwon, Kyung-Hwan
    • Imaging Science in Dentistry
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    • v.45 no.3
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    • pp.199-203
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    • 2015
  • A 59-year-old male who had suffered from multiple myeloma for nine years and had been administered bisphosphonates for seven years visited a dental hospital for pain relief due to extensive caries in his left maxillary molars. The molars were extracted, leaving an exposed wound for three months. The radiograph showed sequestra formation and irregular bone destruction in the left maxilla. Sudden pain and gingival swelling in the right mandibular molar area occurred six months later. The interseptum of the right lower second molar was observed to be necrotic during surgery. These findings coincided with the features of bisphosphonate-related osteonecrosis of the jaw (BRONJ). In this case, the long intravenous administration of bisphosphonates and tooth extraction were likely the etiologic factors of BRONJ in a patient with multiple myeloma; moreover, the bilateral occurrence of BRONJ is a characteristic feature.

Combined Hyperactive Dysfunction Syndrome of the Cranial Nerves

  • Yang, Kyung-Hoon;Na, Joon-Ho;Kong, Doo-Sik;Park, Kwan
    • Journal of Korean Neurosurgical Society
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    • v.46 no.4
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    • pp.351-354
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    • 2009
  • Objective : Combined hyperative dysfunction syndrome (HDS) defined as the combination of HDSs such as trigeminal neuralgia (TN). hemifacial spasm (HFS) and glossopharyngeal neuralgia (GPN), which mayor may not occur simultaneously on one or both sides. We reviewed patients with combined HDS and demonstrated their demographic characteristics by comparing them with those of patients with a single HDS. Methods : Between October 1994 and February 2006, we retrospectively studied a series of 1,720 patients who suffered from HDS and found 51 patients with combined HDSs. We analyzed several independent variables in order to evaluate the prevalence and etiologic factors of combined HDS. Results : The combined HDS group accounted for 51 of 1,720 (2.97%) patients with HDS; 27 cases of bilateral HFS, 10 cases of bilateral TN and 14 cases of HFS with TN. Their mean age was 52.1 years (range, 26-79 years). There were 5 men and 46 women. Seven patients had synchronous and 44 patients metachronous onset of HDSs. By comparison of combined and single HDS groups, we found that age and hypertension were closely associated with the prevalence of combined HDS (p<0.05). Conclusion : This study revealed that combined HDS was very rare. Hypertension and age might be the most important causative factors to evoke combined HDS.

Factors Associated with Cheyne-Stokes Respiration in Acute Ischemic Stroke

  • Kim, Yuna;Kim, Seongheon;Ryu, Dong Ryeol;Lee, Seo-Young;Im, Kyoung Bin
    • Journal of clinical neurology
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    • v.14 no.4
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    • pp.542-548
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    • 2018
  • Background and Purpose Cheyne-Stokes respiration (CSR) is frequently observed in patients with acute stroke. There have been conflicting opinions about the associations of CSR with the location and size of the lesion. We aimed to better define the clinical relevance and pathogenesis of CSR in acute stroke. Methods We investigated patients who had been admitted with acute ischemic stroke and received an overnight sleep apnea test. We collected data on demographics, risk factors, etiologic subtypes, initial vital signs, clinical course of the stroke, and parameters associated with respiratory events during the sleep apnea test. We performed a multivariate logistic regression analysis to determine the factors associated with CSR. Results Among 182 patients, 35 patients showed CSR in sleep apnea testing. Large-artery atherosclerosis or cardioembolism, bilateral hemispheric involvement, atrial fibrillation, low left-ventricle ejection fraction (LVEF), and left atrium (LA) enlargement were all associated with the presence of CSR. Multivariate analysis revealed that the previous modified Rankin Scale (mRS) score, bilateral hemispheric involvement, low LVEF, and LA enlargement were significantly associated with CSR. Subgroup analysis with large-artery atherosclerosis without cardiac disease revealed that the previous mRS score is the only independent factor associated with CSR. Conclusions CSR frequently occurs in strokes involving large arteries or due to cardioembolism, regardless of the location and severity of the stroke. Predisposing conditions such as preexisting neurologic disability, low LVEF, and LA enlargement are associated with CSR in acute stroke.