• Title, Summary, Keyword: erythrosine

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Removal Charateristics of Erythrosine by Activated Carbon Adsorption (활성탄 흡착에 의한 Erythrosine의 제거 특성)

  • Lee, Jong-Jib;Yoon, Sung-Wook
    • Journal of Korean Society of Environmental Engineers
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    • v.31 no.7
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    • pp.499-504
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    • 2009
  • Erythrosine is used a food coloring, ink and dye, etc. but erithrosine is rarely used in United States due to its known hazards. The adsorption characteristics of erythrosine by granular activated carbon were investigated in the batch adsorber and the packed column. The adsorptivity of activated carbon for erythrosine were largely improved by pH control. When the pH was 11 in the sample, the erythrosine could be removed 98% of initial concentration. It was estabilished that the adsorption equilibrium of erythrosine on granular activated carbon was successfully fitted by Freundlich isotherm equation in the concentration range from 10mg/L to 1,000mg/L. The characteristics of breakthrough curve of activated carbon packed column depend on the design variables such as initial concentration, bed height, and flow rate.

Optimum Treatment Parameters for Photodynamic Antimicrobial Chemotherapy on Streptococcus mutans Biofilms (Streptococcus mutans biofilm에 대한 광역동 치료의 최적조건에 관한 연구)

  • Choi, Seojung;Park, Howon;Lee, Juhyun;Seo, Hyunwoo;Lee, Siyoung
    • THE JOURNAL OF THE KOREAN ACADEMY OF PEDTATRIC DENTISTRY
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    • v.42 no.2
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    • pp.151-157
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    • 2015
  • The purpose of this study was to evaluate the effects of Photochemotherapy using a combination of erythrosine and standard halogen dental curing lights on the viability of Streptococcus mutans in the biofilm phase. To investigate the optimum treatment parameters, the researchers controlled the concentration of erythrosine, light irradiation time and the treatment time of erythrosine. The higher concentration of erythrosine (0, 10, 20, 40, 80 M) in the presence of light irradiation created greater effects in reducing the viability of S. mutans. The results showed a statistically significant difference among the antimicrobial effects in 20, 40, 80 M erythrosine. The higher irradiation time of light (0, 5, 15, 30, 60, 75s) in the presence of erythrosine showed greater effects in reducing the viability of S. mutans. There was statistically significant difference in 30, 60, 75 seconds. The higher treatment time of erythrosine (0, 1, 2.5, 5min) in the presence of erythrosine created greater effects on reduction of S. mutans viability. Statistically significant differences were found between 2.5 and 5 minutes of erythrosine treatment time. The results of this study showed that the photochemotherapy on S. mutans using erythrosine and the halogen dental curing lights conventionally used in dental clinics is effective in the condition of 20-40 M erythrosine concentration, irradiation time over 30 seconds, and erythrosine treatment time over 2.5 minutes.

Effects of Erythrosine on Murine Immune Functions and Methemoglobin Formation (식품 첨가물의 면역독성 및 혈액독성 - Erythrosine이 마우스의 면역기능과 Methemoglobin형성에 미치는 영향 -)

  • 황미경;윤혜정;유충규;문창규
    • Journal of Food Hygiene and Safety
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    • v.2 no.4
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    • pp.191-196
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    • 1987
  • Erythrosine used as a colouring agent in drugs, cosmetics and foods in Korea, was examined for its effects on murine immune system and methemoglobin formation. As immunotoxicologic assay parameters, we adopted circulating leukocytes and immunoorgan weights for pathotoxicology, IgM plaque forming cells and arthus reaction for humoral immunity, delayed hypersensitivity reaction of cell mediated immunity and carbon clearacnce for macrophage function. Erythrosine's effects were observed as follows; 1. Ery throsine showed no significant effects on circulating leulocyte counts and relative immunoorgan weight. 2. Erythrosine diminished IgM plaque forming cells. 3. Erythrosine decreased arthus reaction, in the dose dependent manner. 4. Erythrosine had no significant effect on delayed hypersensitivity. 5. Phagocytic and corrected phagocytic index were not affected. 6. Methemoglobin content was similar in the test and control groups.

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Pharmacological Studies of Erythrosine (Erythrosine의 약리학적(藥理學的) 연구(硏究))

  • Kim, Jin-Hyon;Ahn, Young-Ran;Kim, Hack-Seang
    • Journal of Pharmaceutical Investigation
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    • v.12 no.3
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    • pp.93-99
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    • 1982
  • The effects of erythrosine on motility of frog heart, rabbit duodenum and uterus isolated, and on mice intestinal motility and voluntary activity were investigated. The effect of erythrosine $2.3{\times}10^{-5}M$ on isolated frog heart showed a slight decrease of the amplitude of motility, and the heart motility stopped in $3.5{\times}10^{-4}M$. With the administration of erythrosine $3.4{\times}10^{-4}M$, the isolated rabbit duodenum showed a remarkable contraction and this effect was inhibited by atropine $1.4{\times}10^{-7}M$. The administration of erythrosine $2.3{\times}10^{-3}M$, produced a contractile effect on the isolated rabbit uterus, and the motility of $6.9{\times}10^{-3}M$ started to increase in contractions at first and finally stopped, keeping in continuous contractions. The effects of erythrosine 0.5, 1.0, 10, and 20mg/kg on mice intestinal motility were not significantly different from this of the normal control. With 20 and 40mg/kg of erythrosine, the effects on voluntary activity showed the decrease of 21 and 58% respectively, and voluntary activity of the mice pretreated with erythrosine 20 and 40mg/kg, induced by C. N. B. 30mg/kg showed the decrease of 57 and 78% respectively in contrast with the normal control group.

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Effects of Erythrosine on the Cholesterol Oxidative Stability in an Aqueous Model System (수용성 모형계에서 콜레스테롤의 산화 안정성에 대한 Erythrosine의 영향)

  • Chung, Man-Gon;Kim, Jong-Seung;Shin, Hyo-Sun
    • Korean Journal of Food Science and Technology
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    • v.28 no.1
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    • pp.197-202
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    • 1996
  • The effects of erythrosine on the oxidative stability of cholesterol in an aqueous model system were studied by depleted headspace oxygen and cholesterol oxidation products (COP). As the oncentration of erythrosine was increased, headspace oxygen depletion, 7-COP and total COP increased during storage at $25^{\circ}C$ for 50 hours under the fluorescent light. As the intensity of fluorescent light was increased, amounts of headspace oxygen depleted and COP formed in an aqueous cholesterol dispersion containing erythrosine also increased. Addition of ${\alpha}-,\;{\delta}-$, mixed-tocopherol and ${\beta}-carotene$ resulted in the enhanced oxidative stability of an aqueous cholesterol dispersion containing erythrosine during the fluorescent light storage.

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Studies on the Adsorption of Erythrosine in the Suspension of Antibiotics (항생물질 현탁액중에서 Erythrosine의 흡수에 관한 연구)

  • 백우현;송영준;김정우;김종갑
    • YAKHAK HOEJI
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    • v.23 no.3_4
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    • pp.133-140
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    • 1979
  • The adsorption of erythrosine in the aliphatic alcohols by antibiotics such as ampicillin anhydrous, ampicillin trihydrate, amoxicillin trihydrate, cephalexin monohydrate was studied. The adsorption isotherms were all described with Freudlich equation. From the various experimerts, it was found that the adsorption of erythrosine by antibiotics in the aliphatic alcohols was affected by the solubility of adsorbents. The adsoption in the mixture of aliphatic alcohols and water is related with the dielectric constant of mixed solvents. According to increase in the pH values of aqueous solution, the adsorption of erythrosine for antibiotics is decreased, but increased in the mixture of aliphatic alcohols and water. The adsorption of erythrosine in the suspension of antibiotics showed a correlation with the temperature. Colloidal silica which is used as stabilizer had a favorable effect on the adsorption of erythrosine in the suspension of antibiotics.

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BIOCOMPATIBILITY OF FOOD COLORING AGENTS TO DEVELOP NEW DENTAL PLAQUE DISCLOSANTS (새로운 치면세균막 착색제 개발을 위한 식용색소의 생체적합성 연구)

  • Lee, Kwang-Hee
    • THE JOURNAL OF THE KOREAN ACADEMY OF PEDTATRIC DENTISTRY
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    • v.26 no.1
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    • pp.14-24
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    • 1999
  • The purpose of study was to develop new dental plaque disclosants which could replace erythrosine. Three food coloring agents(Red No.40, Blue No.1, and Mixed Green), erythrosine and fluorescein were tested for their color difference, antibacterial property, and biocompatibility. Color difference of Red No.40 was greater than that of erythrosine as concentration of solution increased. Color differences of Blue No.1 and Mixed Green were smaller than that of red dyes. Erythrosine showed obvious antibacterial property, but food coloring agents showed almost no antibacterial property. The taste and sensation of erythrosine was the worst, and the taste of Red No.40 and the sensation of Mixed Green were the most tolerable. Erythrosine stained dental plaque and oral soft tissue most deeply and long, and Blue No.1 was the next in the depth and longevity of stain.

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Enhancement of Erythrosine Photodynamic Therapy against Streptococcus mutans by Chlorhexidine (Streptococcus mutans에 대한 클로르헥시딘과 Erythrosine 광역동 치료의 상승효과)

  • Park, Jongcheol;Park, Howon;Lee, Siyoung
    • THE JOURNAL OF THE KOREAN ACADEMY OF PEDTATRIC DENTISTRY
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    • v.40 no.4
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    • pp.241-246
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    • 2013
  • The purpose of this study was to investigate the synergistic effects of erythrosine sensitized with a conventional halogen curing unit and sub-minimal bactericidal concentration(sub-MBC) of chorhexidine on bacterial viability of Streptococcus mutans in planktonic state. Sub-minimal bactericidal concentration of chlorhexidine was added into wells containing bacteria and erythrosine. The range of concentrations tested for chorhexidine was from 0.0000001% to 0.001%. The irradiation of the bacterial suspensions was performed for 15 sec with a conventional halogen curing unit light. In another set of experiment, the effects of 0.001% chlorhexidine were observed by adding chlorhexidine into wells containing the sub-minimal bactericidal concentration of erythrosine. At the concetration of 0.001% chlorhexidine, there were no antibacterial effects in the absence of erythrosine PDT(p < 0.05). At the concentraton of $1{\mu}M$ erythrosine, there was no photodynamic therapy effect in the absence of chlorhexidine(p < 0.05). But in the presence of sub-minimal bactericidal concentration of erythrosine with light exposure, the addition of 0.001% chlorhexidine increased the bactericidal rate(p < 0.05). A combination of erythrosine PDT with sub-MBC chlorhexidine resulted in a significant reduction in bacterial counts when compared to the case with the absence of chlorhexidine.

The Effect of Erythrosine-mediated Photodynamic Therapy on Intraorally Formed Biofilm on Titanium Surface

  • Park, Se-Hwan;Lee, Si-Young;Chang, Beom-Seok;Um, Heung-Sik;Lee, Jae-Kwan
    • International Journal of Oral Biology
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    • v.37 no.3
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    • pp.103-108
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    • 2012
  • The purpose of this study was to assess the efficacy of photodynamic therapy (PDT) using erythrosine and a halogen light source to treat a biofilm formed on a machined surface titanium disk in vivo. Ten volunteers carried an acrylic appliance containing six machined surface titanium disks on the upper jaw over a period of five days. After the five days of biofilm formation period, the disks were removed. PDT using 20 ${\mu}M$ erythrosine and halogen light was then applied to the biofilms formed on the disks. Experimental samples were divided into a negative control group (no erythrosine and no irradiation), E0 group (erythrosine 60s + no irradiation), E30 group (erythrosine 60s + halogen light 30s), and E60 group (erythrosine 60s + halogen light 60s). Following PDT, the bacteria in the biofilm were found to be detached from each disk. Each suspension with detached bacteria were diluted and cultivated on a blood-agar plate for five days under anaerobic conditions. The cultivated bacterial counts in the E60 group were significantly lower than the control group (86.4%) or E0 group (76.7%). In the experimental groups also, the light exposure time and bacterial counts showed a negative correlation. In conclusion, PDT using erythrosine and halogen light has bactericidal effects on biofilms formed on a titanium disk in vivo. Notably, applying 20 ${\mu}M$ erythrosine and 60 seconds of halogen light irradiation had a significantly potent effect.

Study on Adsorption Characteristics of Erythrosine Dye from Aqeous Solution Using Activated Carbon (활성탄에 의한 에리스로신 염료수용액의 흡착특성에 관한 연구)

  • Lee, Jong-Jib
    • Applied Chemistry for Engineering
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    • v.22 no.2
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    • pp.224-229
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    • 2011
  • Adsorption characteristics of erythrosine dye onto the activated carbon has been investigated in a batch system with respect to initial concentration, contact time and temperature. Kinetic studies of the adsorption of erythrosine were carried out at 298 K, using aqueous solutions with 100, 250 and 500 mg/L concentration of erythrosine. The adsorption process followed a pseuo second order model, and the adsorption rate constant (k2) decreased with increasing the initial concentration of erythrosine. The equilibrium process can be well discribed by Freundlich isotherm in the temperature range from 298 to 318 K. Free energy of adsorption (${\Delta}G^o$), enthalpy (${\Delta}H^o$), and entropy (${\Delta}S^o$) change were calculated to predict the nature the adsorption. The estimated values for ${\Delta}G^o$ were -3.72~-9.62 kJ/mol over the activated carbon at 250 mg/L, indicated toward a spontaneous process. The positve value for ${\Delta}H^o$ indicates that the adsorption of erythrosine dye on activated carbon is an endothermic process.