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A Review on Korean Traditional Medicine Research against Human Papillomavirus Infection and Cervical Dysplasia - Focused on Randomized Controlled Trial of Human Papillomavirus Infection and Cervical Dysplasia - (인유두종 바이러스 감염과 자궁경부 이형성증과 관련된 한방 임상연구 동향 - 무작위 대조 비교 임상시험을 중심으로 -)

  • Chung, Jae-Ryung;Hwang, Deok-Sang;Lee, Jin-Moo;Jang, Jun-Bock;Lee, Chang-Hoon
    • The Journal of Korean Obstetrics and Gynecology
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    • v.32 no.4
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    • pp.55-66
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    • 2019
  • Objectives: This review is to figure out evidence that suggests the effectiveness of Korean Medicine treatments against Human Papilloma virus (HPV) infection and Cervical Dysplasia. Methods: Studies on HPV infection and cervical dysplasia were searched through 5 databases: Oriental Medicine Advanced Searching Integrated System (OASIS), Korean Studies Information Service System (KISS), the Journal of Korean Obstetrics & Gynecology, China Academic Journal (CAJ), Pubmed. After that, the articles were extracted with reference point of Korean Traditional Medicine. Results: 21 studies were included lastly according to selection criteria. In 21 studies, HPV turning - negative rate of Korean Medicine treatment group was higher than the control treatment group. Conclusions: 21 studies indicates that Korean Medicine treatment is effective in HPV infection and Cervical Dysplasia.

A RADIOGRAPHIC STUDY OF CEMENTOMA (백악종에 관한 방사선학적 연구)

  • Hwang Eui Hwan;Lee Sang Rae
    • The Journal of Korean Academy of Maxillofacial Radiology
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    • v.16 no.1
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    • pp.113-126
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    • 1986
  • This study was undertaken to document and better define this condition to help clarify this clinical and radiographic appearances by the analysis of clinical and radiographic features of cementoma. A study was made of a series of 104 cases with cementoma. This investigation of cementoma revealed the following features: 1. The female occurred in 73% of periapical cemental dysplasia and benign cementoblastoma, and 80% of cementifying fibroma. 2. 40% of periapical cemental dysplasia occurred in the fifth decades, and 73% of benign cementoblastoma during the second and third decades, while there was no age predilection in the cementifying fibroma. 3. 63% of periapical cemental dysplasia occurred in the mandibular anterior region. 91% of benign cementoblastoma and 80% of cementifying fibroma occurred in the mandibular premolar and/or molar region. 4. There were no cases complaining the associated clinical signs and subjective symptoms in the periapical cemental dysplasia, however the patient complained the pain in 36% of benign cementoblastoma and 40% of cementifying fibroma. 5. There were no cases expanding the cortical plates in the periapical cemental dysplasia, however 73% of benign cementoblastoma and all of 5 cases of cementifying fibroma showed the expansion of cortical plates. 6. Several radiographic features of the periapical cemental dysplasia were shown: a. 29% of the cases had multiple lesions. b. 53% of the cases were in the mature stage. c. During the osteolytic stage, the alveolar lamina dura was lost in 89% of the cases.

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Osteosarcoma Arising in a Polyostotic Fibrous Dysplasia: A Case Report (다골성섬유형성이상에서 발생한 골육종: 증례 보고)

  • Suh, Kyung-Jin
    • Investigative Magnetic Resonance Imaging
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    • v.11 no.1
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    • pp.49-53
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    • 2007
  • Fibrous dysplasia is a skeletal developmental anomaly of the bone-forming mesenchyme that manifests as a defect in osteoblastic differentiation and maturation. It is a nonhereditary disorder of unknown cause. In fibrous dysplasia, the medullary bone is replaced by fibrous tissue, which appears various imaging findings. It is usually an incidental finding, generally not requiring further investigation. However, fibrous dysplasia may be complicated by pathologic fracture, and rarely by malignant degeneration. We present the image findings of a 44-year-old man who had a chondroblastic osteosarcoma arising from polyostotic fibrous dysplasia in the femur. Evidence of cortical destruction on plain radiography and soft tissue mass in the lesion on MR images suggested a tumor of malignant transformation.

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Simple Bone Cyst and Fibrous Dysplasia Occurring Simultaneously in Both Mandibles: Case Report

  • Kim, Hong-Soon;Song, Chan-Jong;Seol, Dong-Ju;Lee, Jae-Wook;Lee, Baek-Soo;Kwon, Yong-Dae;Ohe, Joo-Young;Lee, Jung-Woo;Choi, Byung-Joon
    • Journal of Korean Dental Science
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    • v.6 no.1
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    • pp.34-40
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    • 2013
  • Fibrous dysplasia is a benign fi bro-osseous lesion wherein normal bone is replaced with an excessive proliferation of cellular fibrous connective tissue intermixed with irregular bony trabeculae. Fibro-osseous lesions like fibrous dysplasia are often associated with non-epithelial cysts, such as simple bone cyst. The etiologic and pathogenic relationships between fi brous dysplasia and simple bone cyst have not been conclusively established. Nonetheless, the mechanism of cyst formation in fibro-osseous lesion associated with simple bone cyst can be said to differ from that of the typical simple bone cyst of the jaws. This article reports a case of bilateral lesions including fi brous dysplasia and simple bone cyst on each site and reviews the pathogenesis of cyst formation in the fibro-osseous lesion.

A Case of Intractable Cervical Dysplasia Patient Treated with Korean Medicine for Three Months (3개월간 한방치료를 받은 난치성 자궁경부 이형증 환자 1례)

  • Han, Jae-Hyun;Kim, Sung-Su;Seong, Shin;Bang, Sun-Hwi
    • The Journal of Korean Obstetrics and Gynecology
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    • v.25 no.4
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    • pp.154-160
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    • 2012
  • Objectives: This report is aimed to investigate the efficacy of Korean medicine including intravenous Cultivated Wild Ginseng(Panax ginseng C.A. Meyer) Pharmacopuncture(CWGP) with intractable cervical dysplasia patient. Methods: A 49-year-old woman who was diagnosed as cervical dysplasia on Feb 2012 was treated with Korean medicine for 3 months. Korean medicine includes intravenous CWGP, acupuncture, moxibustion and herbal medicine. The effect of therapies was evaluated with human papillomavirus deoxyribonucleic acid(HPV DNA) testing. And lower limb cold sense and genital pruritus were recorded with Visual Analogue Scale(VAS). Results: Lower limb cold sense and genital pruritus were decreased from VAS 8-9(2012.04.11.) to VAS 1-2(2012.07.10.). HPV DNA test result was changed from positive to negative. From these results, this report suggests that the Korean medicine, especially CWGP may be a useful method to treat intractable cervical dysplasia. Conclusions: This report shows that Korean medical treatments are effective on intractable cervical dysplasia.

Interdisciplinary treatment for ectodermal dysplasia (외배엽 이형성증환자의 협진치료)

  • Kim, Jin-Hee;Hoe, Young-Ku;Oh, Jang-Kyun
    • The korean journal of orthodontics
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    • v.30 no.6
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    • pp.739-745
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    • 2000
  • Ectodermal dysplasia is a hereditary disease characterized by a congenital dysplasia of one or mote ectodermal structures. Characteristic manifestations Include scanty hair and eyebrows, pigmented and hyperkeratinized skin around the eyes and mouth, frontal bossing with prominent supraorbital ridges, nasal bridge depression and dental anomalies. Hyperthermia or unexplained high fever as a result of the deficiency of sweat glands is common medical history. Findings of intraoral structures are anodontia or oligodontia with conical crowns. Consequently, generalized spacing and loss of vertical dimension of occlusion. Interdisciplinary approach has been performed to treat a 10-year old boy with ectodermal dysplasia. Orthodontists and a prosthodontist worked together on this case, and the result was satisfactory.

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TREATMENT OF A PATIENT WITH CLEIDOCRANIAL DYSPLASIA USING IMPLANT-SUPPORTED BAR OVERDENTURE: A CASE REPORT (바 피개의치를 이용한 쇄골두개이형성증 환자의 치료: 증례보고)

  • Jang, Jung-Hui;Song, Min-Seok;Kim, Hyeon-Min;Kim, Nam-Hun;Eom, Min-Yong;Koo, Hyun-Mo;Yi, Jun-Kyu;Jeong, Jong-Cheol;Kim, Se-Woong
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.28 no.1
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    • pp.80-86
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    • 2006
  • Cleidocranial dysplasia is rare inherited skeletal dysplasia. It was first reported by Martin in 1765. Subsequently, Marie and Sainton independently documented the criteria of the disease. Cleidocranial dysplasia is a bone disorder caused by a defect in the CBFA1 gene of chromosome 6p21. This gene guides osteoblastic differentiation and appropriate bone formation. Patient with cleidocranial dysplasia has maxillary deficiency, high and narrow palate, prolonged retention of primary teeth, unerupted permanent teeth and supernumerary teeth. Therapeutic options in these patients include of autotransplantation of selected impacted teeth, forced eruption of permanent teeth, full denture, overdenture and implant-supported prosthesis. We report a patient with cleidocranial dysplasia. This patient was treated with implant supported bar overdenture. Despite of gene defect that affects osteoblastic activity, bone remodeling and osseointegration occurred in our patient. So, we report this case with review of literature.

Role of MRI and Plain Radiograph to Diagnose Fibrous Dysplasia Mimicking Metastasis on PET/CT in a Patient with Breast Cancer (유방암환자의 양전자방출단층촬영술에서 암 전이로 오인된 섬유형성이상 진단의 자기공명영상과 단순촬영의 역할)

  • Cho, Song-Mee;Jee, Won-Hee;Yoo, Ie-Ryung;Lee, Ah-Won;Chung, Yang-Guk
    • The Journal of the Korean bone and joint tumor society
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    • v.16 no.1
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    • pp.47-50
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    • 2010
  • Fibrous dysplasia is a common benign disorder of bone in which normal bone marrow is replaced with fibro-osseous tissue. As PET/CT is increasingly used for the staging of different malignant disease, incidentally found fibrous dysplasia with increased FDG uptake may mimic metastasis. We report on a 46-year-old woman with fibrous dysplasia who underwent PET/CT because of suspected recurrence of breast cancer and was misdiagnosed as a bony metastasis with a focal FDG uptake on left proximal femur. This lesion was interpreted as fibrous dysplasia based on MRI in addition to the plain radiographs. We conclude that MRI in addition to radiography may help to differentiate fibrous dysplasia mimicking metastasis on PET/CT in the patients with malignancy.

Monostotic Fibrous Dysplasia in the Spine - A Case Report - (척추에 발생한 단골성 섬유 이형성증 - 증례 보고-)

  • Yang, Jun-Young;Lee, June-Kyu;Lee, Jun-Ho;Yang, Jae-Hoon
    • The Journal of the Korean bone and joint tumor society
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    • v.11 no.2
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    • pp.188-193
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    • 2005
  • Fibrous dysplasia is a condition characterized by the replacement of the medullary component of predominantly long bone with fibrous tissues. The monostotic form of the fibrous dysplasia occurs more frequent than the polyostotic form. Only the twenty three previous cases of vertebral involvement in monostotic fibrous dysplasia have been reported. Authors experienced a case of monostotic fibrous dysplasia of the third lumbar vertebra, so we report this case. Report details the diagnosis and treatment of a 34 years old man with back pain from monostotic fibrous dysplasia of the third lumbar vertebra. We discuss the experience in the consideration of previous report to recommend the optimal management of this disease.

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A Review on Korean Traditional Medicine Research against Cervical Dysplasia - Focused on Studies of Cervical Cancer and Cervical Dysplasia- (자궁경부 이형증과 관련한 한의약 연구 고찰 - 자궁경부암 및 자궁경부 이형증 논문을 중심으로 -)

  • Yoo, Jeong-Eun;Lee, Ji-Yeon;Yoon, Young-Jin
    • The Journal of Korean Obstetrics and Gynecology
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    • v.26 no.4
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    • pp.191-203
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    • 2013
  • Purpose: This review is to figure out evidence that suggest effectiveness of Korean Medicine treatments against cervical dysplasia. Methods: Studies on cervical cancer and cervical dysplasia were searched through 6 databases: Korean Studies Information Service System(KISS), National Discovery for Science Leaders (NDSL), Korea Institute of Science and Technology Information (Korean TK), Oriental Medicine Advanced Searching Integrated System (OASIS), the Journal of Korean Medicine, and the Journal of Korean Obstetrics & Gynecology. After that, the articles were extracted with reference point of Korean Traditional Medicine. Results: 37 articles were included lastly according to selection criteria. 3 of them were case reports on cervical dysplasia, and 34 were in-vitro studies on Human Papilloma Virus (HPV) positive cancer cell. In case reports, acupuncture, moxibustion, medical herbs and pharmacoacupuncture were used for treatments of cervical dysplasia with about 3 months. Experimental studies on cervical cancer cell showed that several herbs function with clear heat, eliminate stasis (淸熱解毒, 化瘀消腫) have anti-cancer effects inducing apoptosis. Conclusions: The results of articles are not enough to use in practice. Therefore, we indicates more advanced research methodology as follows: development of Korean Medicine treatment protocol with oral and external, in-vivo experimental study, and evaluation immunity index.