• Title, Summary, Keyword: breast ultrasonography

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Effects of Age, Breast Density and Volume on Breast Cancer Diagnosis: A Retrospective Comparison of Sensitivity of Mammography and Ultrasonography in China's Rural Areas

  • Wang, Feng-Liang;Chen, Fei;Yin, Hong;Xu, Nan;Wu, Xiao-Xiang;Ma, Jing-Jing;Gao, Shen;Tang, Jin-Hai;Lu, Cheng
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.4
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    • pp.2277-2282
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    • 2013
  • Purpose: Mammography has been confirmed as the only effective mode to improve the prognosis of patients with breast cancer in Western developed countries, but might not be a good choice in other areas of the world. One of the major challenges in China is to determine an optimal imaging modality for breast cancer screening. This study was designed to clarify the sensitivity of ultrasonography compared with that of mammography in rural China. Methods: We retrospectively studied the sensitivity of mammography and ultrasonography based on 306 breast cancer patients detected by the program of "screening for cervical cancer and breast cancer" performed in Chinese rural areas between January 2009 and December 2011, and analyzed the effects of age, breast density and volume on the sensitivity. Results: Stratified analysis showed that the sensitivity of breast ultrasonography was significantly higher than that of mammography in premenopausal patients (81.4% vs. 61.1%, p=0.02), in women ${\leq}$ 55 years of age (82.2% vs. 63.4%, p<0.01), in the high breast density group (American College of Radiology [ACR] levels 3-4) (85.9% vs. 60.6%, p<0.01) and in the small breast volume group (${\leq}$ 400 ml) (87.1% vs. 66.7%, p<0.01). Age had a significant effect on sensitivity of mammography (breast density and volume-adjusted odds ratio, 6.39; 95% confidence interval, 2.8-14.4 in age group > 55 compared to age group ${\leq}$ 45), but not that of ultrasonography. Neither breast density nor volume had significant effect on sensitivity of mammography or ultrasonography. Conclusions: Ultrasonography is more sensitive than mammography in detecting breast cancer in women under 55 year-old Chinese, especially in those with high-density and relatively small breasts.

Common Variants in the PALB2 Gene Confer Susceptibility to Breast Cancer: a Meta-analysis

  • Zhang, Yi-Xia;Wang, Xue-Mei;Kang, Shu;Li, Xiang;Geng, Jing
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.12
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    • pp.7149-7154
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    • 2013
  • Objective: Increasing scientific evidence suggests that common variants in the PALB2 gene may confer susceptibility to breast cancer, but many studies have yielded inconclusive results. This meta-analysis aimed to derive a more precise estimation of the relationship between PALB2 genetic variants and breast cancer risk. Methods: An extensive literary search for relevant studies was conducted in PubMed, Embase, Web of Science, Cochrane Library, CISCOM, CINAHL, Google Scholar, CNKI and CBM databases from their inception through September 1st, 2013. A meta-analysis was performed using the STATA 12.0 software and crude odds ratios (ORs) with 95% confidence intervals (CIs) were calculated. Results: Six case-control studies were included with a total of 4,499 breast cancer cases and 6,369 healthy controls. Our meta-analysis reveals that PALB2 genetic variants may increase the risk of breast cancer (allele model: OR>1.36, 95%CI: 1.20~1.52, P < 0.001; dominant model: OR>1.64, 95%CI: 1.42~1.91, P < 0.001; respectively). Subgroup analyses by ethnicity indicated PALB2 genetic variants were associated with an increased risk of breast cancer among both Caucasian and Asian populations (all P < 0.05). No publication bias was detected in this meta-analysis (all P > 0.05). Conclusion: The current meta-analysis indicates that PALB2 genetic variants may increase the risk of breast cancer. Thus, detection of PALB2 genetic variants may be a promising biomarker approach.

Mammography and Ultrasonography Reports Compared with Tissue Diagnosis - An Evidence Based Study in Iran, 2010

  • Akbari, Mohammad Esmaeil;Haghighatkhah, Hamidreza;Shafiee, Mohammad;Akbari, Atieh;Bahmanpoor, Mitra;Khayamzadeh, Maryam
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.5
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    • pp.1907-1910
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    • 2012
  • Background: Breast cancer is the most prevalent cancer and the fifth cause of cancer death in Iranian women. Early detection and treatment are important for appropriate management of this disease. Mammography and ultrasonography are used for screening and evaluation of symptomatic cases and the main diagnostic test for breast cancer is pathological. In this study we evaluated mammography and ultrasonography as diagnostic tools. Methods: In this cross-sectional study 384 mammography and ultrasonography reports for 255 women were assessed, divided into benign and malignant groups. Suspected cases were referred for pathology evaluation. The radiologic and pathologic reports were compared and also comparison was performed based on age groups (more and less than 50 years old), history of breastfeeding and gravidity. Statistical analysis was performed by SPSS. Results: The mean ages of malignant and benign cases were $49{\pm}11.6$ and $43{\pm}11.2$ years, respectively. Sensitivity and specificity for mammography were 73% and 45%, respectively. Sensitivity and specificity for ultrasonography were 69% and 49%, respectively. There were statistical differences between specificity of mammography in patients based on factors such as history of gravidity, breastfeeding and sensitivity in patients equal or more than 50 years old and less. Conclusion: Factors affecting different results in mammography and ultrasonography reports were classified into three groups, consisting of skill, experience and training of medical staff, and setting of instruments. It is recommended that health managers in developing countries pay attention the quality of setting and man power more than current status. Policy-makers and managers must establish guidelines regarding breast imaging in Iran.

A Case Report of Juvenile Hypertrophy of the Breast in a 15-Year-Old Girl: Presented with Asymmetric Breast Enlargement and a Focal Mass-like Lesion

  • Park, Jae Yeon;Kim, Sung Hun;Jung, Na Young;Kang, Bong Joo;Lee, Ah Won;Jin, Min-Sun
    • Investigative Magnetic Resonance Imaging
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    • v.23 no.2
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    • pp.175-178
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    • 2019
  • Juvenile hypertrophy of the breast is a rare condition, leading to hyperplastic breast anomalies in adolescents. Here, we report a case involving a 15-year-old girl, presented with asymmetric enlargement of the left breast. Pronounced parenchymal thickening was found on initial ultrasonography (US). MRI and second-look US revealed a focal mass-like lesion on the left mid-lateral breast, confirmed as juvenile hypertrophy of the breast on pathology.

A surgically confirmed case of breast sparganosis showing characteristic mammography and ultrasonography findings

  • Park, Jae-Hwan;Chai, Jee-Won;Cho, Nariya;Paek, Nam-Sun;Guk, Sang-Mee;Shin, Eun-Hee;Chai, Jong-Yil
    • The Korean Journal of Parasitology
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    • v.44 no.2
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    • pp.151-156
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    • 2006
  • A case of breast sparganosis was confirmed by surgical excision of a worm (fragmented into 5 pieces) in a 59-year-old Korean woman suffering from a palpable mass in the left breast. Mammography and ultrasonography characteristically revealed the presence of several well-defined, isodense and hypoechoic tubular masses, in the upper quadrant of the left breast, each mass consisting of a continuous cord- or worm-like structure. During surgery, a long segment of an actively moving sparganum of Spirometra sp. and 4 small fragments of the same worm, giving a total length of 20.3 cm, were extracted from the upper outer quadrant of the left breast and the axillary region. The infection source remains unclear, because the patient denied ingesting any snake or frog meat or drinking untreated water.

Factor analysis using S-detect Method in Breast Ultrasound (유방 초음파 검사 시 S-detect 방법을 활용한 인자 분석)

  • Chun, Hye Ri;Jang, Hyon Chol;Cho, Pyong Kon
    • Journal of the Korean Society of Radiology
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    • v.13 no.1
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    • pp.9-14
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    • 2019
  • This study aimed to investigate the performance of the S-detect method in breast ultrasonography and to determine how to reduce unnecessary biopsy by comparing the results of the S-detect method and biopsy. Thirty patients who had undergone breast ultrasonography between August and October 2018 and were scheduled to undergo biopsy because of the presence of breast nodules were retrospectively analyzed. The McNemar test was performed to determine whether detection of a malignant breast mass significantly differed between the S-detect method and biopsy. The following results were obtained from the analysis of the S-detect method: sensitivity, 90.9%; specificity, 84.21%; validity, 86.66%; positive predictive value, 76.92%; and negative predictive value, 94.11%. Analysis of the degree of agreement between the S-detect method and biopsy revealed a kappa value as high as 0.724 (p < 0.05), exhibiting good agreement between the two methods. The S-detect method in breast ultrasonography is diagnostically valuable in terms of distinguishing between malignant and benign breast masses, and if used properly before breast biopsy, unnecessary biopsy can be reduced.

Autologous Fat Graft in the Reconstructed Breast: Fat Absorption Rate and Safety based on Sonographic Identification

  • Kim, Hong Youl;Jung, Bok Ki;Lew, Dae Hyun;Lee, Dong Won
    • Archives of Plastic Surgery
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    • v.41 no.6
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    • pp.740-747
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    • 2014
  • Background Autologous fat graft has become a useful technique for correction of acquired contour deformity in reconstructed breasts. However, there remains controversial regarding the efficacy and safety of the practice for reconstructive breast surgery. Methods A retrospective review was performed on 102 patients who had secondary fat grafting after breast reconstruction. Fat harvest, refinement and injection were done by Coleman's technique. All patients were followed up postoperatively within 1 month and after 6 months including physical examination and ultrasonography. In 38 patients, the reabsorption rate was calculated by serial changes of thickness between skin and pectoral fascia in the ultrasonic finding. Locoregional recurrence rate was compared with control group of 449 patients who had breast reconstruction without fat graft in the same time period. Results Average 49.3 mL fat was injected into each breast. The most common location of fat graft was upper pole, followed by axilla, lower and medial breasts. During 28.7 months of average follow-up period, 2.9% of total patients had symptoms of palpable mass on fat graft side and ultrasonography identified fat necrosis and cyst formation in 17.6% of the patients. Calculated fat reabsorption rate was 32.9%. Locoregional recurrence was occurred in 1 patient (0.9%) and the rate was not different significantly with control group (2%). Conclusions Although further studies are required to provide surgeons with definitive guidelines for the implementation of fat grafting, we propose autologous fat graft is an efficient and safe technique for secondary breast reconstruction.

Breast Cavernous Hemangioma with Increased Size on Ultrasonography: A Case Report (초음파에서 크기가 증가한 유방 해면상 혈관종: 증례 보고)

  • Kim, Kwang-Min;Kim, Ji-Young;Kim, Soung Hee;Jeong, Myeong Ja;Kim, Soo Hyun;Kim, Jae Hyung;Bae, Kyung Eun;Lee, Ji Hae;Kang, Mi-Jin;Kim, Tae Gyu
    • Journal of the Korean Society of Radiology
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    • v.79 no.6
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    • pp.311-314
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    • 2018
  • Cavernous hemangioma of the breast is a rare benign vascular tumor. It is usually diagnosed as non-palpable mass during imaging examination, incidentally. Common sonographic finding of the breast hemangioma is a superficially located, oval shape, circumscribed margin mass. But the appearance of breast hemangioma is variable and it can be difficult to diagnose in preoperatively. Here, we report a 68-year-old female case with palpable breast mass and increased size on follow up ultrasonography.

Electrical Impedance Tomography as a Primary Screening Technique for Breast Cancer Detection

  • Akhtari-Zavare, Mehrnoosh;Latiff, Latiffah A
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.14
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    • pp.5595-5597
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    • 2015
  • Electrical impedance tomography (EIT) is a new non-invasive, mobile screening method which does not use ionizing radiation to the human breast. It is based on the theory that cancer cells display altered local dielectric properties, thus demonstrating measurably higher conductivity values. This article reviews the utilisation of EIT in breast cancer detection. It could be used as an adjunct to mammography and ultrasonography for breast cancer screening.

The Study of Incidence Disease Categories on Breast Medical Examination in Some Area (일부지역 유방검사의 질환별 발생 빈도에 관한 연구)

  • Kwak, Byung-Joon;Im, In-Chul;Ji, Tae-Jeong
    • Journal of radiological science and technology
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    • v.30 no.4
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    • pp.357-363
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    • 2007
  • The breast cancer occurrence have been increase yearly. Consequently the effort for early discovery or prevention is necessary. The study investigated the age distribution rate and a disease distribution occurrence rate in the breast medical examination of Ulsan city area. Breast medical examination distribution ratio it preferred the breast ultrasound with mamography 38.8% breast-ultrasonogrphy 61.2% to be investigated. The disease categories distribution was various from breast-ultrasound medical examination and it was investigated with becomes ramification. The reading find was many most infiltrating duct carcinoma from 40 age stage. The ductal carcinoma in situ was many from 50 age stage. The most many disease was investigated HP(Heterogenous dense nodule or mass parenchyma pattern) with 29.2%. Also the breast abscess or mastitis disease is confirmed only the breast-ultrasonography examination, even from the outside disease it was investigated with the fact that the breast-ultrasound raises the discrimination.

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