• Title, Summary, Keyword: anti-aging

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A study on analyzing the terms describing anti-aging effects in Dongeuibogam to propose the methodology for selecting medicinal herbs related to anti-aging effects (『東醫寶鑑』에 수록된 항노화 효능어와 이에 근거한 항노화 한약재 선별 방법론 연구)

  • Lee, Dong-Woo;Baek, Jin-Ung
    • Journal of Korean Medical classics
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    • v.27 no.2
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    • pp.25-48
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    • 2014
  • Objectives : This study aims to analyze the terms describing anti-aging effects in Dongeuibogam, and to propose the methodology for selecting medicinal herbs related to anti-aging effects. Methods : We considered aging or anti-aging theories by reviewing the major literature in korean medicine or traditional chinese medicine, and then we deduced the concepts describing anti-aging effects and the medicinal herbs for anti-aging effects. We investigated the medicinal herbs based on the terms describing anti-aging effects in Dongeuibogam and drew the methodology for selecting and classifying the medicinal herbs related to anti-aging. Results & Conclusions : The following conclusions could be drawn. 1. A set of causes and signs of aging in Dongeuibogam and a set of therapies for alleviating the aging signs in Chengumikbang, Yanglobongchinseo, and Nolohangeon was found. 2. Anti-aging effects should not be confused with disease treatments. Therefore, we defined the medical terms of anti-aging effects as "the terms expressing the effect of delaying or alleviating the subjective or objective signs of aging concretely". Based upon the terms of anti-aging effects, we defined the medicinal herbs for anti-aging effects as "the medicinal herbs whose effects are described in medical terms expressing the effects of delaying or alleviating the subjective or objective signs of aging concretely". 3. We considered Lycii Fructus, Asparagi Tuber in Dongeuibogam as examples of medicinal herbs whose effects are described in medical terms expressing anti-aging effects. It shows that we can select medicinal herbs for anti-aging effects by comparing the effects of 937 single therapies in Dongeuibogam to the terms describing anti-aging effects defined in this study. Futhermore, the results could be utilized as the basic materials of experimental study on anti-aging.

Anti-aging Joobang(酒方)s in Dongeuibogam : Identification of candidates by text mining (『동의보감(東醫寶鑑)』에서 발굴한 항노화 효능을 가진 주방(酒方) 후보군에 대한 연구)

  • Lyu, Jeong-Ah;Baek, Jin-Ung
    • Journal of Korean Medical classics
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    • v.28 no.2
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    • pp.47-60
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    • 2015
  • Objectives : To investigate the anti-aging effects of Joobang(酒方) on Dongeuibogam Methods : We analyzed the effect of 27 Joobang(酒方)s on Dongeuibogam and finally extracted 11 Joobang(酒方)s, which have anti-aging effects. Results & Conclusions : 1. We finally selected 12 terms of Joobang(酒方)'s anti-aging effect on Dongeuibogam. 2. We finally selected 11 Joobang(酒方)s as anti-aging candidates. 3. Twelve terms of Joobang(酒方)'s anti-aging effect and 11 candidates with anti-aging effects were classified into five categories. 4. We finally selected 17 medicinal herbs from the 11 candidates. 5. Eleven candidate anti-aging Joobang(酒方)s and 17 medicinal herbs proposed in this study have the potential to reduce the time required for experimental and clinical research for developing novel compounds with anti-aging effects.

A Study on Strategies to Galvanize the Anti-aging Industry (항노화산업 활성화 방안에 관한 연구)

  • Jung, Tae-Young;Goh, Young-Gon;Chung, Hae-Joo
    • The Korean Journal of Health Service Management
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    • v.10 no.2
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    • pp.145-154
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    • 2016
  • Objectives : Because people have increasingly more interest in their quality of life, the anti-aging industry has grown worldwide. The purpose of this study is to suggest strategies for galvanizing the anti-aging industry in Korea. Methods : To accomplish this aim, we explored the definition, classification, problem and activating strategies of the anti-aging industry through a systematic review. Results : From the results, the following suggestions are given: planning a national strategy to galvanize the anti-aging industry, establishing an anti-aging research institute, developing a business model, developing an anti-aging cluster, statistics development and an information system related to anti-aging, training personnel, and legislation. Conclusions : The anti-aging industry has the potential to reduce health expenses through early intervention of diseases due to aging and through activation of the national economy by win-win growth of the industry related to aging. Therefore, understanding the anti-aging industry as well as political support is critical.

Anti-aging Discourses Targeted at Women in Their 20s -Young Fashion Magazine 『Céci』- (20대 여성 대상 안티에이징 담론 분석 -영패션잡지 『쎄씨(Céci)』를 중심으로-)

  • Shin, Hyeyoung;Ahn, Jinhyun;Ha, Jisoo
    • Journal of the Korean Society of Clothing and Textiles
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    • v.41 no.4
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    • pp.599-614
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    • 2017
  • With the increasing media representation of aging as negative and abnormal, anti-aging products and discourses are spreading to younger generations. This paper analyzes the anti-aging discourse in a fashion magazine targeted towards women in their 20s. It quantitatively analyzes the historical development of the antiaging industry and discourses from 1994 to 2014 in the magazine "$C{\acute{e}}ci$". It also analyzes the patterns of signification associated with aging in the magazine through the use of critical discourse analysis. This paper identifies five major discourses -"segmentation of the definitions of youthful appearance", "scientific and medical discourse", "self-care discourse", "prevention of aging", and "social values of youthful appearances". The paper finds that the construction of anti-aging discourses towards women in their 20s is heavily influenced by the close link between the anti-aging industry and the fashion media. It also confirms the ideology of self-development though a rigorous appearance-management that is strongly imposed on Korean women and subsequently reproduced in an anti-aging discourse towards women in their 20s.

A novel nicotinoyl peptide, nicotinoyl-LVH, for collagen synthesis enhancement in skin cells

  • Kim, Hyoung Shik;Ryu, Seung Hwan;Kim, Hye In;Cho, Seung Hee;Lee, Jeong Hun;Han, Byung Suk;Lee, Kyung Rok;Moh, Sang Hyun
    • Journal of Applied Biological Chemistry
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    • v.59 no.3
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    • pp.239-242
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    • 2016
  • A novel Nicotinoyl fused peptide, Nicotinoyl-LVH, was synthesized by solid phase peptide synthesis method, purified, and tested in cultured skin cells. Nicotinoyl-LVH enhanced the expression level of collagen mRNA and its fragments in fibroblasts. These data show that this novel Nicotinoyl peptide is a promising biomaterial in the anti-aging functional cosmetic market.

Advancement of Mass Purification of Porphyra 334 from Porphyra yezoensis by Applying Direct Current (직류전류 인가를 통한 김으로부터 포피라334의 대량 정제 고도화)

  • Jang, Sung Joo;Lee, Jeong Hun;Seo, Hyo Hyun;Lee, Sak;Kim, Jiyeon;Kim, Doyoun;Moh, Sang Hyun
    • Journal of Marine Bioscience and Biotechnology
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    • v.12 no.1
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    • pp.66-74
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    • 2020
  • Marine algae contain a variety of substances, such as mycosporine-like amino acids, which can defend against UV irradiation. Among them, Porphyra-334 derived from Porphyra yezoensis is attracting attention as a novel active ingredient for anti-aging cosmetics because of its excellent anti-oxidative, anti-inflammatory, and wound-healing properties through promoting skin cell migration. In this study, a process using direct current (DC) for increasing the yield of large-scale purification of Porphyra-334 was developed. When DC was applied to obtain Porphyra-334 efficiently, the purification time was shortened by approximately 1/4 compared with the process wherein DC was not applied; moreover, the yield of purification was improved.

A Study of Possibilities on Developing of Traditional Convenience Foods for Anti-aging Control an Analysis of Public Perspectives (노화 제어를 위한 전통 편의식 개발 가능성에 대한 연구)

  • Bok, Hye-Ja;Choi, Soo-Keun
    • Journal of the East Asian Society of Dietary Life
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    • v.18 no.3
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    • pp.322-330
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    • 2008
  • This study was performed to the possibility of developing anti-aging convenient food that is to Koreans' taste. Editor: this abstract appears to describe a study of public opinion and not related to the development of anti-aging convenient foods. In total, The 150 adults, living in Seoul (Korea), participated in this study in the capacity of subjects. Editor: You really have to mention the age-range of the subjects, as senility is an old age disease. In particular, you talk about the intention of subjects (discussed below) to buy anti-aging food products. This would be directly related to their age, as I assume that older people would be more concerned about senility that relatively younger subjects. They were randomly assigned to 25 groups. In result initial descriptive analysis revealed that, 82 percent of subjects awoke to were aware of senility, and the while 26.7 percent were seriously thought of it concerned. Furthermore, The 58.7 percent said that believed food has the possibility has a role in of controlling senility, and the while 64.0 percent said stated that senility may be controlled by eating constitutional foods. Further comparative analysis of In the case of the group of which members subjects have been who were trying to control senility revealed that their, the reliance on food general and constitutional food was significantly higher than those who have not tried to do so did nothing. The From the 61.3 percent have been of subject who were trying to control senility, from among them, the 74.0 percent and the 22.7 percent were relied on physical taking exercises and anti-aging foods, respectively. Likewise, it was ascertained When asked whether subjects intend to purchase anti-aging convenient food if it was is developed. The 67.3 percent and the 72.7 percent indicated their intentionded to purchase the normal product and constitutional products, respectively. Resultantly, anti-aging convenient food was in demand to some extent. Given that anti-aging products are in high demand, In such a case, senile severity (p<0.05), anti-aging possibility in constitutional foods (p<0.001) and anti-aging action (p<0.001) are regarded as variables in the purchase of the normal products. In the case of relation to constitutional products, anti-aging possibility in constitutional food (p<0.001) and anti-aging action (p<0.001) were regarded as variables.

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Characterization of Isoflavone in Callus Culture from Glycine max (L.) Merr. Phytoplacenta (대두 태좌조직의 캘러스배양에 의한 Isoflavone 동정)

  • Kang, Hyo-Seok;Min, Ji-Aee;Jung, Hae-Soo;Lee, Jeong-Hun;Shin, Dong-Sun;Kim, Eun-Ae;Kim, Young-Jun;Moh, Sang-Hyun
    • Proceedings of the KAIS Fall Conference
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    • pp.235-238
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    • 2012
  • 본 연구는 Glycine max (L.) Merr.의 태좌부위를 순수 분리하여 callus 세포를 유도하고 2차 대사산물인 isoflavone류에 속하는 daidzein의 생산성을 증진시킬 수 있는 방법을 찾는데 있다. 배양된 callus를 다양한 용매를 사용하여 추출하고, 추출물을 액체 크로마토그래피로 분석해 daidzein 함량의 차이를 확인하였다. 또한 핵자기공명분광법으로 50% 에탄올 추출물 내에 daidzein이 함유되어 있음을 증명하였다.

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Anti-aging Effect of Phytochemical fused Peptides (피토케미칼 융합 펩타이드 신소재의 안티에이징 효능)

  • Cho, Moon-Jin;Seo, Hyo-Hyun;Lee, Yu-Ri;Moh, Ji-Hong;Moh, Sang-Hyun;Cho, Suk-Hyung;Kim, Young-Jun;Lee, Jeong-Hun
    • Proceedings of the KAIS Fall Conference
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    • pp.187-190
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    • 2012
  • 본 연구는 피토케미칼과 펩타이드의 융합된 신소재의 항노화 효능에 관한 연구이다. 대표적인 피토케미칼인 갈릭산 및 시키믹산에 식물유래 Pentapeptide인 Exorphin을 융합시켜 만든 Galloyl Exorphin 및 Shikimoyl Exorphin은 콜라겐 합성능 및 항염증 효능 등을 보여주었다. 이러한 피토케미칼 융합 펩타이드 신소재는 피토케미칼이 가진 Stability 및 Solubility를 향상시키며, 피토케미칼 및 펩타이드 소재가 가진 각각의 효능을 유지시켰다. 이러한 결과는 피토케미칼 융합 펩타이드 소재가 항노화 소재로서 화장품 포물레이션에 널리 활용될 수 있음을 의미한다.

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Anti-aging Effect of Cycloheterophyllin in UVA-irradiated Dermal Fibroblasts (자외선 조사에 의해 노화된 섬유아세포에서 Cycloheterophyllin의 항노화 효능)

  • Shim, Joong Hyun
    • Korean Journal of Pharmacognosy
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    • v.50 no.4
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    • pp.285-290
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    • 2019
  • This study was carried out to identify the skin anti-aging effect of cycloheterophyllin on dermal fibroblasts. To elucidate anti-aging effects of cycloheterophyllin on dermal fibroblasts, I measured cell viability, mRNA expressions, and Collagen, type I/matrix metallopeptidase 1(MMP1)-ELISA assay. In this study, I investigated the effects of cycloheterophyllin on Collagen, type I, alpha 1(COL1A1)/Collagen, type III, alpha 1(COL3A1)/MMP1/Superoxide dismutases/Catalase(CAT) mRNA expressions and Collagen, type I/MMP1 protein production. Quantitative Real-time RT-PCR showed that cycloheterophyllin increased mRNA level of COL1A1/COL3A1/CAT genes and collagen, type I protein by ELISA assay compared to UVA-treated dermal fibroblasts. Furthermore MMP1 mRNA and protein expressions were decreased by cycloheterophyllin treatment. These observations revealed that cycloheterophyllin increased anti-aging effects in dermal fibroblasts. Therefore, I identified the anti-aging effects of cycloheterophyllin, and these results showed that the cycloheterophyllin can be a considerable potent ingredient for skin anti-aging. Based on this, I anticipated further researches about cycloheterophyllin for mechanism to develop not only cosmetics but for healthcare food or medicine.

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