• Title, Summary, Keyword: alopecia

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A Literature Review of Alopecia Areata (油風에 關한 文獻的 考察)

  • Jang, Sung-Eun;Chae, Byung-Yoon
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.9 no.1
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    • pp.84-98
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    • 1996
  • We think that we know what alopecia is. But in detail, we have nothing of alopecia areata. Many kinds of alopecia make us be confused. So, I studied the history ( name, cause, treatment etc,) of alopecia areata through the oriental and occidental medical books. As a result, the investigation of alopecia areata was led to the next conclusions 1. Synonyms of alopecia areata are Bandok(斑禿), Docbal(禿髮), Guyjidu(귀지두), Guychedu(鬼剃頭), Gyobalsun(咬髮癬). 2. Generally, the cause of alopecia areata is classified into three groups. Those are hyeolheopungjo(血虛風燥), Chichehyeoleo(氣滯血瘀), Gansinbujoc(肝腎不足). 3. The important internal uses of alopecia areata are Sineungyangjin-Dan(神應養眞丹), Soyosan plus Tonggyuhwalhyeoltang(逍遙散合通竅活血湯), Chilbomiyuom-Dan(七寶美髥丹) etc. 4. The important external uses of alopecia areata are haeaetang(海艾湯), Suncheukbackyeop(鮮側柏葉), Old ginger(老薑), Leaf of mulberry tree(桑葉) etc. 5. The kinds of Acupunture therapy are Maehwachim(梅花針), Chilsungchim(七星針), Ear acupunture(耳針) etc.

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Factors Associated with Severity of Alopecia Areata

  • You, Hye Rin;Kim, Seong-Jin
    • Annals of dermatology
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    • v.29 no.5
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    • pp.565-570
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    • 2017
  • Background: Alopecia areata is the most common cause of localized, nonscarring alopecia. Unfortunately, there are few data regarding clinical features and epidemiology of alopecia areata in Korean patients, and its clinical course and treatment response rates are unpredictable. Objective: This study strived to investigate the differences in clinical profiles according to disease severity and to determine risk factors for severe alopecia areata. Methods: A total of 1,137 patients from 2006 to 2015 were analyzed retrospectively. Patients were subdivided into two groups: mild-to-moderate and severe alopecia areata. The groups were compared on the basis of age of onset, duration, sex, family history, comorbid disorders including autoimmune diseases, nail changes, and laboratory test results. Results: Eight hundred eighty-three patients were in the mild-to-moderate alopecia areata group and 254 patients were in the severe group. Average onset age was $30.77{\pm}17.66years$ and $30.60{\pm}16.75years$ in the mild-to-moderate and severe groups, respectively. Disease duration was statistically longer in the severe group. Male sex, nail changes, and thyroid diseases were more common in the severe group. Hypertension, diabetes mellitus, dyslipidemia, atopic dermatitis, and family history did not differ between groups. Of the serologic values, only alkaline phosphatase was considerably differing between groups. Male sex, presence of nail changes, and disease duration greater than one year were identified as significant risk factors for severe alopecia areata. Conclusion: This is the largest case analysis in Korean patients with alopecia areata. Clinical profiles stratified by disease severity warrant further study.

A Study of Clinical features and classifications of alopecia patients in Korean medicinal clinic (탈모증 환자의 한의학적 임상 유형에 대한 연구)

  • Lee, Tae-Hoo;Moon, Jung-Bae;Jeong, Jee- Haeng;Leem, Kang-Hyun;Kim, Hee-Taek
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.22 no.3
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    • pp.153-166
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    • 2009
  • Objectives : This study was planed to evaluate clinical status of the alopecia patients who had visited Korean medicine clinic. And the result from this study would provide a standard in Korean medical diagnostic and classification method of alopecia. Methods : Clinical records of 183 patients with alopecia seen from January 2004 to April 2005 at Korean medical clinic was examined. They were classified into 4 different types according to chief complains besides alopecia by 2 Korean medical doctors. Results and conclusions : We made clinical analysis of patients of alopecia from January 2004 to April 2005. Among the alopecia patients who visit Korean medical clinic, people age between 20 and 30 had high ratio. The duration from the recognition of initial hair loss to the time of the first visit to the Korean medical clinic was less than 12 months in 20.8%(38/138), and less than 60 months in 72.2% (132/183). The condition of alopecia was more worse than other alopecia patients who visit the west medical clinic. Also the ratio with increased temperature of face or scalp is chief complaint except alopecia in alopecia patients was high in men and the ratio with dysfunction of digestive system or chronic weakness was high in women. Among the incidence of alopecia, the androgenic alopecia was most in number; 43.7%(80/183) and the sex distribution showed 83 men and 100 women.

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The Current Status of Korean Medicine Treatment of Alopecia : Focusing on Case Reports (탈모의 한의학적 치료에 대한 국내 현황 : 증례보고를 중심으로)

  • Kweon, So-Hyoun;Hong, Seok-Hoon
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.32 no.3
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    • pp.164-185
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    • 2019
  • Objectives : This study is carried out to analyze the use of Korean medical treatments on alopecia in Korean medicine clinical studies published in South Korea. Methods : Based on OASIS and KTKP with the keyword 'alopecia', published in 1996-2019.4.23., total 23 studies have been found and analyzed. We analyzed Korean medical treatment used in each cases, and investigated the tendency of use for each treatment. Results : 369 cases in 23 research papers were selected. Herbal medicine, acupuncture, pharmacopuncture, external medicine and other therapy were used as treatment for Alopecia. Herbal medicine with a cooling effect was mainly used. The acupoints mainly used were GV20, ST8, GB5, ST36, HT8, PC6, BL66. Pharmacopunctures used to treat alopecia were CF, HP, HH, BV, etc. The average duration of Korean medicine treatment was 144 days. After Korean medicine treatment, 292 cases presented improvement or complete recovery. Conclusions : According to the results, we were able to discover the current status of Korean medicine treatment of alopecia. Based on this result, further studies will be needed to establish the primary treatment direction of alopecia.

Psychosocial Reaction Patterns to Alopecia in Female Patients with Gynecological Cancer undergoing Chemotherapy

  • Ishida, Kazuko;Ishida, Junko;Kiyoko, Kanda
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.3
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    • pp.1225-1233
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    • 2015
  • This study aims to clarify the psychosocial reactions of female patients with gynecological cancer undergoing chemotherapy and in the process of suffering from alopecia and to examine their nursing support. The target group comprised female patients who had received two or more cycles of chemotherapy, were suffering from alopecia, and were aged 30-65. Data were collected from semi-structured interviews, conducted from the time the patients were informed by their doctors that they might experience alopecia due to chemotherapy to the time they actually experienced alopecia and until they were able to accept the change. Inductive qualitative analysis was employed to close in on the subjective experiences of the cancer patients. The results showed the existence of six phases in the psychosocial reactions in the process of alopecia: phase one was the reaction after the doctor's explanation; phase two was the reaction when the hair starts to fall out; phase three was the reaction when the hair starts to intensely fall out; phase four was the reaction when the hair has completely fallen out; phase five was the reaction to behavior for coping with alopecia; and phase six was the reaction to change in interpersonal human relationships. The results also made it clear that there are five types of reaction patterns as follows: 1) treatment priority interpersonal relationship maintenance type; 2) alopecia agitated interpersonal relationship maintenance type; 3) alopecia agitated interpersonal relationship reduction type; 4) alopecia denial interpersonal relationship reduction type; and 5) alopecia denial treatment interruption type. It is important to find out which of the five types the patients belong to early during treatment and provide support so that nursing intervention that suits each individual can be practiced. The purpose of this study is to make clear the process in which patients receiving chemotherapy come to accept alopecia and to examine evidence-based nursing care on patients with strong mental distress from alopecia.

Perception, Attitudes, Preparedness and Experience of Chemotherapy-Induced Alopecia among Breast Cancer Patients: a Qualitative Study

  • Kim, Im-Ryung;Cho, Ju-Hee;Choi, Eun-Kyung;Kwon, In-Gak;Sung, Young-Hee;Lee, Jeong-Eon;Nam, Seok-Jin;Yang, Jung-Hyun
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.4
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    • pp.1383-1388
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    • 2012
  • Objectives: Regardless of its negative impact on quality of life, little is known about the importance of alopecia from the patients' perspective. This study aimed to explore the whole experience of chemotherapy-induced alopecia among Korean breast cancer patients including perception, attitudes, preparedness, and changes after alopecia. Methods: Patients expected to experience or had experienced alopecia were recruited at a tertiary hospital in Seoul, Korea. Semi-structured in-depth interviews were performed in 21 patients. Recurrent issues were identified and placed into thematic categories. Results: All patients think that appearance is important and they pay attention to how they look like. They had negative perceptions about alopecia. Patients were not well prepared for alopecia, and experienced substantial physical, psychological and social distress. Lack of information and limited social support combined with negative images of cancer made it difficult for patients to overcome the trauma and deterred them from usual daily activities resulting in poor quality of life. Conclusions: Patients were not well prepared for alopecia and negative perceptions, lack of preparedness, and limited social support and resources increased alopecia-related distress. Educational programs for preparing patients to cope with alopecia distress and advocate activities to change people's negative perception about alopecia are needed to reduce the burden imposed by alopecia in cancer patients.

Parental Experiences with Chemotherapy-Induced Alopecia among Childhood Cancer Patients in Indonesia

  • Gunawan, Stefanus;Broeke, Chloe ten;Ven, Peter van de;Arnoldussen, Marijn;Kaspers, Gertjan;Mostert, Saskia
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.4
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    • pp.1717-1723
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    • 2016
  • Background: This study assessed parental experiences with chemotherapy-induced alopecia among children with cancer treated at an Indonesian academic hospital. Materials and Methods: Fifty parents of childhood cancer patients were interviewed using semi-structured questionnaires. Results: The moment that hair fell out was the moment that parents (84%) had to admit their child had cancer. Alopecia was a traumatizing painful experience (46%). Active strategies to hide alopecia, mainly hats, were used by 66% of children, while 34% never covered their bald head. If money had not been an issue, 40% would use another strategy. Alopecia made children limit outdoor daily activities (78%) and engagement with others (60%). Significantly more children from high-educated (95%) than low-educated (60%) parents received sympathy from other people (P=0.012). Significantly more Christian (29%) than Muslim (0%) families confirmed that alopecia lowered the quality of life (P=0.046). Most parents (82%) had no prior plans about alopecia management, yet for significantly more girls (26%) than boys (0%) such plans existed (P=0.044). Parents received most information about alopecia from other parents (66%). Parents (92%) needed more alopecia education from doctors. Of all school-attending children, 53% were bullied and 47% did not want to attend school due to alopecia. Significantly more high-educated than low-educated families received pity from teachers and pupils (94% vs. 0%, P=0.004), and acceptance by pupils (81% vs. 0%, P=0.021). Conclusions: Alopecia is a severe, far-stretching side-effect of chemotherapy with physical, psychological and social consequences for children and parents. Parents should be better informed about occurrence and impact of alopecia. Extra attention is required to facilitate children's return to school. Healthcare providers should facilitate optimal supportive care through open dialogue and provision of educational m aterials for parents, children and their community.

Effects of Early Cell Damage from Repetitive Intermittent Fever Exposure in Alopecia Progression and Evaluation of New Candidate Drugs: Ibuprofen, Menthol, and Cetirizine (간헐적 발열 반응에 의한 세포 손상과 이와 관련된 탈모 치료를 위한 신 후보물질 연구)

  • Lim, Sung Cil;Moon, Hong Seop
    • Korean Journal of Clinical Pharmacy
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    • v.26 no.3
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    • pp.187-194
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    • 2016
  • Background: Alopecia areata (AA) is a very disturbing and expensive disorder in which the exact etiology is not known and it is yet to be treated completely well. Most alopecia patients exhibit some inflammation in the hair follicles regardless of the causes. The clinical symptoms of alopecia present very diversely while the prime symptom is local intermittent fever which are related to inflamed cells. Methods: This study aimed to evaluate how repetitive intermittent fever can damage the normal human dermal fibroblast (NHDF) cells and investigated the cytotoxic and proliferative effects after application of new candidate drugs (ibuprofen, menthol, cetirizine) for alopecia in comparison to minoxidil. Results: This study demonstrated that ibuprofen, menthol, or/and cetirizine can prevent or slow down the damage of NHDF cells from intermittent fever in early alopecia. Aggressive preventative intervention with those drugs before complete destruction of hair follicle by excessive repetitive fever, is a very important step for alopecia therapy and these drugs are recommended as candidate drugs for alopecia in the future. Conclusion: Aggressive preventative intervention with drugs before complete destruction of hair follicles (NHDF cells) by excessive repetitive fever is a very important step for alopecia therapy or progression.

Clinical Study of Emotional State and Personality Characteristics in Patients with Alopecia Aerata (원형탈모증 환자의 정서상태와 성격특성에 관한 임상적 연구)

  • Lee, Kyung-Kyu;Paik, Ki-Chung
    • Korean Journal of Psychosomatic Medicine
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    • v.5 no.2
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    • pp.158-167
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    • 1997
  • Objectives: This study was aimed to investigate the emotional state and personality characteristics of alopecia aerata patient and to determine whether these characteristics are similar with those of neurotic patient. Methods : 20 alopecia aerata patients, 20 neurotic patients, and 20 normal healthy controls were studied. Beck Depression Inventory(BDI), State and Trait Anxiety Inventory(STAI) and Korean standardized edition of Catell's 16 Personality factors Questionnaire(16PF) were used for assessment. Results: 1) Total score of BDI was higher in neurosis group than alopecia aerata group and normal control group(p<0.05). Inspire of statistical non-significance, total score of in alopecia aerata group was higher than normal control group. 2) Total scores of state anxiety and trait anxiety in alopecia aerata and neurosis group were significantly higher than normal control group(p<0.001). 3) In first-stratum source traits of 16PF, normal control group was significantly higher than alopecia aerata group and neurosis group in B-factor(intelligence) and C-factor(ego-strength)(p<0.05). Alopecia aerata group and neurosis group were significantly higher than normal control group in O-factor(guilt-proneness) and $Q_4-factor(tension,\;anxiety)$(p<0.001). 4) In second-stratum source traits of 16PF, alopecia aerata group and neurosis group were significantly higher than normal control group in ANX-factor(anxiety)(p<0.05). Conclusions : These results suggest that emotional state and personality characterstics of patients with alopecia aerata are a distinguishable different to compare with normal control, and are very similar with those of neurotic patients. The authors propose that psychiatric management in patient with alopecia aerata will be more benificial.

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Retrospective Study about the Causes and the Effects of Korean Medicine Treatment on Alopecia - Focused on Acquired Febrile Alopecia - (탈모증 유발요인과 한의학적 치료 효과에 대한 후향적 연구 - 후천적 열성 탈모를 중심으로 -)

  • Lee, Jung-Hwan;Jang, Jin-Young;Yoon, YoungJoon;Cho, Ah-Ra;Shin, Hyun-Jin;Jung, Sang-Uk;Jeong, Yeon-Ho;Kang, Yeo-Reum
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.26 no.2
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    • pp.30-44
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    • 2013
  • Objectives : The purpose of this study is to report the causes and the effects of korean medicine treatment on alopecia. Methods : 1050 patients with alopecia, who had visited oriental medical clinics from July 2011 to October 2012, were analyzed by self-assessments. And 153 patients of them were treated with korean medicine treatment for 3 months. Treatment results were evaluated by patients' self-assessments and global & enlarged photographic reviews. Results : 1. The gender ratio of male to female was 2:1 and most patients belonged to the 20~30 year old group. 2. Family history of baldness in alopecia patients was a total of 57.3%, paternal 44.4% and maternal 21.2%. 3. Subjective symptoms of fever in parietal region was a total of 97.4% in alopecia patients. 4. After 1 month treatment, the fever in the parietal region was decreased by 37.3% of patients. And their subjective hair loss was also significantly decreased. 5. After 3 months of treatment, the global photographic review was improved by 56.2% of the patients and the enlarged photographic review was significantly improved by 5.2% in patients' total hair count. Conclusions : A significant number of alopecia patients were young and less relative in genetic alopecia causes was less relevant than the past. Recent causes of alopecia were more concerned with the fever in parietal region. According to that reason, cooling effect korean medicine treatment was expected to be effective for febrile alopecia, and actually had significant effects on this study. For future studies, it's long term treatment and follow up studies are needed.