• Title, Summary, Keyword: alcohol consumption

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The Effect of the Levels of Dietary Zinc and Alcohol Consumption on Lipid Metabolism in the Rats (식이성 아연과 알코올의 섭취 수준이 흰쥐의 지질 대사에 미치는 영향)

  • 김명희
    • Journal of Nutrition and Health
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    • v.24 no.2
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    • pp.87-96
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    • 1991
  • This study was undertaken to investigate the effect of the levels of dietary Zn and alcohol consumption on lipid metabolism in Sprague-Dawley male rats weighing 80 to 90g for eight weeks. Ninety rats were divided into nine groups according to Zn levels and alcohol consumption such as no alcohol group[low Zn diet group(<1ppm. LZ) control Zn diet group(30ppm. CZ) high Zn diet group(60ppm, HZ)] 10% alcohol consumption group[the same Zn levels as no alcohol group LZLA, CZLA, HZLA] 20% alcohol consumption group[the same Zn levels as no alcohol group, LZHA, CZHA, HZHA] The results obtained were summarized as following : 1) In the serum total cholesterol increased with increasing dietary Zn levels but decreased with alcohol consumption. HDL-cholesterol decreased with alcohol consumption. Triglyce-ride in alcohol group was higher than no alcohol group. In alcohol group triglyceride increased with decreasing dietary Zn levels. 2) In the liver total lipid in alcohol group was higher than no alcohol group HA group showed a significant increase. Triglyceride increased with alcohol consumption. 3) In the serum and liver Zn content increased with increasing dietary Zn levels but decreased with alcohol consumption.

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The Study of Alcohol Consumption and Nutritional Status of University Male Freshman in Rural Area (일부 지방 대학 남자 신입생의 알코올 섭취와 영양소 섭취상태에 관한 연구)

  • Choe, Mi-Gyeong;Seung, Jeong-Ja;Kim, Mi-Hyeon
    • Journal of the Korean Dietetic Association
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    • v.7 no.3
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    • pp.267-273
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    • 2001
  • The purpose of this study was to investigate the relationship between alcohol consumption and nutritional status of university male freshman in Chungnam area. The total of 111 subjects took part in the study and, they were observed general characteristics, alcohol consumption status, and nutrient intake using questionnaires. The mean age, height, weight, and BMI of the subjects were 19.3 years, 174.3㎝, 65.2㎏, and 21.5㎏/$m^2$ respectively. The mean alcohol consumption, and energy intake from alcohol were 7.8g/day, 55.3kcal/day. A significant number of subjects(48.2%) answered their frequency of alcohol consumption was once 2 weeks. Only 4.6% of subjects answered never drink. In almost subjects, alcohol consumption have been stared since they were adolescents, and major type of alcoholic beverage was 'soju'. The mean energy intake was 1985.6kcal and, energy ratio from carbohydrate, protein, fat was 58 : 15 : 27. There were significantly positive correlation among alcohol consumption and, body weight(p<0.05), intake of food, (p<0.05), energy(p<0.001), animal fat(p<0.05), fiber(p<0.05), vitamin $B_2$(p<0.05) and niacin(p<0.05). The alcohol consumption period showed a significantly positive correlation with alcohol consumption per one time(p<0.05). In summary, high consumption of alcohol in subjects was observed. Also, increase of alcohol consumption was related to weight gain and nutritional imbalance. Therefore, it is need that nutrition education for prevention of high alcohol consumption in university freshman and adolescents.

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Associations of alcohol consumption and alcohol flush reaction with leukocyte telomere length in Korean adults

  • Wang, Hyewon;Kim, Hyungjo;Baik, Inkyung
    • Nutrition Research and Practice
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    • v.11 no.4
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    • pp.334-339
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    • 2017
  • BACKGROUND/OBJECTIVES: Telomere length is a useful biomarker for determining general aging status. Some studies have reported an association between alcohol consumption and telomere length in a general population; however, it is unclear whether the alcohol flush reaction, which is an alcohol-related trait predominantly due to acetaldehyde dehydrogenase deficiency, is associated with telomere length. This cross-sectional study aimed to evaluate the associations of alcohol consumption and alcohol flush reaction with leukocyte telomere length (LTL). SUBJECTS/METHODS: The study included 1,803 Korean adults. Participants provided blood specimens for LTL measurement assay and reported their alcohol drinking status and the presence of an alcohol flush reaction via a questionnaire-based interview. Relative LTL was determined by using a quantitative polymerase chain reaction. Statistical analysis used multiple linear regression models stratified by sex and age groups, and potential confounding factors were considered. RESULTS: Age-specific analyses showed that heavy alcohol consumption (> 30 g/day) was strongly associated with a reduced LTL in participants aged ${\geq}65years$ (P < 0.001) but not in younger participants. Similarly, the alcohol flush reaction was associated with a reduced LTL only in older participants who consumed > 15 g/day of alcohol (P < 0.01). No significant alcohol consumption or alcohol flush reaction associations with LTL were observed in the sex-specific analyses. CONCLUSIONS: The results suggest that older alcohol drinkers, particularly those with the alcohol flush reaction, may have an accelerated aging process.

Alcohol Consumption and the Coronary Heart Disease-Related Risk Factors in Korean Adults;the Third Korea National Health and Nutrition Examination Survey (KNHANES III), 2005 (한국인에서 알코올 섭취가 관상동맥질환 관련 위험요인에 미치는 영향;국민건강영양조사 제3기 (2005년))

  • Park, Sung-Hee;Kang, Young-Hee;Park, Hyun-Young
    • Journal of Nutrition and Health
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    • v.41 no.3
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    • pp.232-241
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    • 2008
  • Moderate alcohol consumption has been known to be associated with reduced risk for coronary heart disease (CHD). We assessed the association between alcohol consumption and CHD-related risk factors [hypertension, diabetes mellitus (DM) , high total cholesterol, high triglyceride (TG), low HDL-cholesterol (HDL-C), and high LDL-cholesterol (LDL-C)] in Korean. After excluding those with extreme intake values, the number of final subjects included in the analysis was 4,662 Korean adults aged over 20 years (1,961 men, 2,701 women) who participate in the 2005 Korean National Health and Nutrition Examination Survey. The subjects were divided into four or five groups; none-alcohol consumption group, moderate alcohol consumption group (<15 or 15.0-29.9 g/d), heavy alcohol consumption group (30-69.9 g/d or ${\geq}$ 70 g/d in men, ${\geq}$ 30 g/d in women). Odds ratios (ORs) were estimated from logistic regression adjusting for potential covariates. Alcohol consumption was inversely associated with low HDL-C in both men and women. However, heavy alcohol intake (${\geq}$ 70 g/d) significantly increased risk for hypertension, DM, and hypertriglyceridemia in men. The frequency of alcohol intake was also associated with CHD risk. The risk for low HDLC was decreased with alcohol consumption (${\geq}$ 1 times/wk), but frequent alcohol intake (${\geq}$ 4 times/wk) increased the risk for hypertension. This study revealed that moderate alcohol consumption has protective effect on CHD-related risk factors in Korean population.

Estimation of High-Risk Drinkers and Drinking Behavior in Korea - Focusing on Korean National Health and Nutrition Examination Survey (KNHANES) and Korean Statistical Information Service Data -

  • Hwang, Seonghee
    • Journal of Environmental Health Sciences
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    • v.46 no.1
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    • pp.65-77
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    • 2020
  • Objectives: This study investigated the average number of drinkers in Korea, the number of high-risk drinkers, the average amount of alcohol consumed by high-risk drinkers, and the types of alcohol consumed according to the characteristics of the group of dependent drinkers. Methods: The results were obtained by analyzing the following data: The Global Status Report on Alcohol and Health; Country Profile 2014; WHO Country Profile 2014; Korea National Health and Nutrition Examination Survey 2014, Korean Statistical Information Service; National Tax Statistics-Liquor Tax; Gallup Drinking Frequency Survey 2015 Results: This study found that a large proportion of drinkers in Korea are already high-risk drinkers, and even among drinkers, alcohol consumption was highly biased. It was reported that 49.8% of men in the problem, abuse, and dependence groups accounted for 92.4% of total alcohol consumption among the male population. Notably, the 9.6% of men making up the dependent group consumed more than 30% of the alcohol ingested among males. Women had significant variations within groups that were considered high-risk and exhibited a large share of alcohol consumption in the problem (10.0% of the female population), abuse (1.8% of the female population), and dependence (1.5% of the female population) groups, constituting 72.8% of total alcohol consumption. The average amount of alcohol consumed by drinkers in Korea seems to have exceeded the level of intake by high-risk groups. Alcohol-dependent groups consumed 900.7 mL of soju, 405.2 mL of table wine, and 2,043.8 mL of beer, which is very similar to the consumption average of 2,031 mL of beer and 895.2 mL of soju in the drinking group. Conclusion: It has been shown that men's dependence on alcohol is serious, and it is possible to infer that alcohol consumption in some vulnerable groups is very high. As the average alcohol intake among alcohol-dependent groups and ordinary drinkers is very similar, it is highly likely that the drinker is an alcohol-dependent consumer in Korea.

Alcohol Consumption, Aldehyde Dehydrogenase 2 Gene Polymorphisms, and Cardiovascular Health in Korea

  • Shin, Min-Jeong;Cho, Yoonsu;Smith, George Davey
    • Yonsei Medical Journal
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    • v.58 no.4
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    • pp.689-696
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    • 2017
  • Alcohol consumption is a serious health issue in Korea in terms of the amount consumed and the behavior related to its consumption. Aldehyde dehydrogenase 2 (ALDH2) is a key enzyme in alcohol metabolism that degrades acetaldehyde to nontoxic acetic acid. The enzyme is coded by the ALDH2 gene, which is commonly polymorphic in East Asian populations. A point mutation in the ALDH2 gene (the rs671 allele) yields an inactive form of ALDH2 that causes acetaldehyde accumulation in the body after alcohol consumption, thereby inhibiting normal alcohol metabolism. Individuals who are homozygous for polymorphism in ALDH2 tend to refrain from drinking alcohol, decreasing their chances of developing alcoholism and exposure to the associated risks. Mendelian randomization (MR) studies have demonstrated that alcohol consumption predicted by ALDH2 genotype is causally related to cardiovascular risks. Moreover, recent MR studies suggest that the ALDH2 variant has mechanistic effects on some disease outcomes or mortality through increased blood levels of acetaldehyde, showing differences therein between heterozygotes ($ALDH2^*2^*2$) and homozygotes ($ALDH2^*1^*2$) in those who consume alcohol. Accordingly, consideration of ALDH2 genotype in alcohol prevention programs is warranted. In conclusion, strategies that incorporate genetic information and provide an evidential basis from which to help people make informed decisions on alcohol consumption are urgently required.

Effect of Alcohol Consumption Characteristics on the Body Mass Index and Blood Pressure (음주특성이 체질량지수 및 혈압에 미치는 영향)

  • Lee, Sang-Min;Song, Hyun-Ju;Sohn, Uy-Dong
    • YAKHAK HOEJI
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    • v.51 no.6
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    • pp.389-401
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    • 2007
  • To investigate effect of alcohol consumption characteristics on the body mass index (BMI) and blood pressure (BP), we performed statistical analyses of data from questionnaire survey among adults over 20 years old, using SPSS WIN program. Alcohol consumption characteristics such as frequency of drinking, amount and toxic degree of alcohol didn't show a significant correlation with BP. Amount of alcohol consumption and BMI showed a positive correlation (r=.264, p<.01). Waist circumference and BMI had the highest correlations with amount of alcohol consumption, which increased with aging.

Alcohol Consumption and Risk of Cancer: a Systematic Literature Review

  • de Menezes, Raquel Ferreira;Bergmann, Anke;Thuler, Luiz Claudio Santos
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.9
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    • pp.4965-4972
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    • 2013
  • This study aimed to discuss the consumption of alcohol as a risk factor for major cancers. We performed a search in the PubMed database, using the following inclusion criteria: meta-analysis published in English in the last 10 years that addressed the relationship between alcohol and the risk of developing cancer. The results indicate that moderate to heavy consumption of alcohol increases the risk of developing cancer of the oral cavity and pharynx, esophagus, stomach, larynx, colorectum, central nervous system, pancreas, breast and prostate. This review did not find any association between alcohol consumption and an increased risk of cancers of the lung, bladder, endometrium and ovary. It was also observed that alcohol consumption may be inversely related to thyroid cancer. Our systematic review has confirmed consumption of alcohol as a risk factor for the development of several types of cancer.

Alcohol consumption and gastric cancer risk in Korea: a case-control study

  • Kim, Mi Hui;Kim, Shin Ah;Park, Chan Hyuk;Eun, Chang Soo;Han, Dong Soo;Kim, Yong Sung;Song, Kyu Sang;Choi, Bo Youl;Kim, Hyun Ja
    • Nutrition Research and Practice
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    • v.13 no.5
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    • pp.425-433
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    • 2019
  • BACKGROUND/OBJECTIVES: The International Agency for Research on Cancer defined alcohol beverages and acetaldehyde derived from alcoholic beverages as a Group 1 carcinogen to humans. However, the association between alcohol consumption and gastric cancer risk has been controversial in Korean. We assessed the relationship between alcohol consumption and gastric cancer risk in Korea through a case-control study. SUBJECTS/METHODS: From 2 hospitals, a total of 316 cases with gastric cancer (208 men, 108 women) were selected and matched to 316 controls by sex and age (${\pm}5years$) during the same duration. The current status, frequency, and amount of alcohol consumption for a year three years ago were assessed by trained interviewers. RESULTS: Alcohol consumption status and frequency did not show any significant association with gastric cancer risk. However, high alcohol consumption (${\geq}20g/day$ for women or ${\geq}40g/day$ for men) significantly increased the risk of gastric cancer (odds ratio (OR) 1.73; 95% confidence interval (CI) 1.05-2.85). Gastric cancer risk was strongly positively associated with alcohol consumption of ${\geq}20g/day$, especially in women (OR 5.62; 95% CI 1.32-23.81). CONCLUSION: The results from this study suggest that excessive alcohol consumption rather than the current status or frequency of alcohol consumption contributes to the increased risk of gastric cancer, especially in women.

Alcohol Consumption and Breast Cancer Survival: A Metaanalysis of Cohort Studies

  • Gou, Yun-Jiu;Xie, Ding-Xiong;Yang, Ke-Hu;Liu, Ya-Li;Zhang, Jian-Hua;Li, Bin;He, Xiao-Dong
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.8
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    • pp.4785-4790
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    • 2013
  • Background and Objectives: Evidence for associations between alcohol consumption with breast cancer survival are conflicting, so we conducted the present meta-analysis. Methods: Comprehensive searches were conducted to find cohort studies that evaluated the relationship between alcohol consumption with breast cancer survival. Data were analyzed with meta-analysis software. Results: We included 25 cohort studies. The meta-analysis results showed that alcohol consumption was not associated with increased breast cancer mortality and recurrence after pooling all data from highest versus lowest comparisons. Subgroup analyses showed that pre-diagnostic or post-diagnostic consumpotion, and ER status did not affect the relationship with breast cancer mortality and recurrence. Although the relationships of different alcohol consumption with breast cancer mortality and recurrence were not significant, there seemed to be a dose-response relationship of alcohol consumption with breast cancer mortality and recurrence. Only alcohol consumption of >20 g/d was associated with increased breast cancer mortality, but not with increased breast cancer recurrence. Conclusion: Although our meta-analysis showed alcohol drinking was not associated with increased breast cancer mortality and recurrence, there seemed to be a dose-response relationship of alcohol consumption with breast cancer mortality and recurrence and alcohol consumption of >20 g/d was associated with increased breast cancer mortality.