• Title, Summary, Keyword: a meta analysis

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Meta-Analysis of AIDS Prevention Programs

  • Kim, Yeon-Hee
    • Korean Journal of Health Education and Promotion
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    • v.3 no.1
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    • pp.129-142
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    • 2001
  • Meta-analysis methods are becoming a central part of research integration in behavioral and medical science studies. The main goal of the meta-analysis is combining the quantitative findings from several studies which address the same research problem and is sharing conclusions in a published report. The purpose of this research is to develop meta-analysis approach to evaluate effectiveness of instructional program design to improve school-age children's knowledge and understanding of Acquired Immune Deficiency Syndrome (AIDS). To achieve this purpose, meta-analysis is applied to analyze and synthesize findings for AIDS instructional programs from several prior studies.

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The Effect of Aquatic Exercise Therapy on Balance in Patients with Chronic Stroke : Meta-Analysis of Studies in Korea (수중운동치료가 만성 뇌졸중 환자의 균형에 미치는 효과 : 국내연구의 메타분석)

  • Lee, Dongjin;Cho, Sunghyoun
    • Journal of The Korean Society of Integrative Medicine
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    • v.6 no.2
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    • pp.1-16
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    • 2018
  • Purpose : This meta-analysis was aimed at guiding future research in stroke treatment and to provide real-world data relating to the effects of aquatic exercise therapy on balance in patients with chronic stroke. Methods : We performed a meta-analysis comprising 22 studies involving aquatic exercise therapy performed between 2006 and 2017. A meta-analysis software program was used to calculate the mean effect size, effect size by intervention, and effect size by outcome. We also performed a meta-regression analysis and an analysis of publishing bias. Results : The mean effect size was 0.563. The effect size by outcome was observed to be the largest for the functional reach test, followed by the Berg balance scale, balance equipment, the Timed Up and Go test and one leg standing. Meta-regression analysis showed that effect size increased with an increase in the duration, number, length of exercise session. Conclusion : Aquatic exercise therapy appears to show a moderate effect on balance in patients with chronic stroke. A meta-analysis is warranted for further research to determine the effects of aquatic exercise on walking, muscle strength, and range of motion.

A Review of the Meta-Analysis in Library and Information Science (문헌정보학분야에서 메타분석 연구에 관한 고찰)

  • Ro, Jung-Soon
    • Journal of the Korean Society for Library and Information Science
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    • v.42 no.1
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    • pp.45-61
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    • 2008
  • Meta-analysis refers to the analysis of analysis. It is the statistical analysis of a large collection of analysis results from individual studies for the purpose of summarizing, integrating and interpreting the inconsistent findings. However, no meta-analysis study has been conducted in Library and Information Science in Korea. This Study introduced the characteristics, basic principles, analysis procesure, and major models of meta-analysis, reviewed meta-analysis studies in Library and Information Science, and discussed major problems in conducting meta-analysis in Library and Information Science especially in Korea.

Effect of aquatic exercise on gait in persons with chronic stroke: a meta-analysis study in Korea

  • Lee, Dong-Jin;Cho, Sung-Hyoun
    • Physical Therapy Rehabilitation Science
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    • v.8 no.2
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    • pp.112-123
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    • 2019
  • Objective: Based on the results of previous studies, it is necessary to analyze gait and discuss and present the effects of aquatic exercise for chronic stroke. The purpose of this study was to present objective data on the effect of aquatic exercise on the gait of persons with stroke by performing a meta-analysis. Design: A systematic review and meta-analysis. Methods: We performed a meta-analysis of 23 studies that investigated the effects of aquatic exercise performed between 2006 and 2017. The studies were searched on the basis of the participants, intervention, comparison, outcomes standard. The quality of the research method was assessed using a tool that can assess the risks posed by each study design. A meta-analysis software program was used to calculate the mean effect size, effect size by intervention, and effect size by outcome. We also performed a meta-regression analysis and an analysis of publication bias. Results: The mean effect size of the patients' gait was 0.65 (p<0.05). The largest effect size by outcome was observed at the 6-m walk test, followed by the 6-minutes walk test, 10-m walk test, and the walking equipment test (p<0.05). The meta-regression analysis showed that the effect size increased with increased duration, number, and length of sessions. Conclusions: Aquatic exercise appears to show a moderate effect on the gait of chronic stroke survivors. Meta-analyses on the effects of aquatic exercise in other patient populations are needed. This study suggests standard criteria establishments for the effect of aquatic exercise on the walking ability of persons with chronic stroke.

Facilitating Pre-Service Elementary Teachers' Productive Reflection on Their Science Teaching through Meta-Analysis of Their Reflective Journals (수업 반성 저널의 메타 분석 활동을 통한 초등 예비교사의 생산적 반성 증진)

  • Yoon, Hye-Gyoung
    • Journal of Korean Elementary Science Education
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    • v.33 no.2
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    • pp.322-334
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    • 2014
  • In this study, the researcher aimed to increase productive reflection of pre-service elementary teachers through meta-analysis of their own reflective journals. The meta-analysis activities are expected to enhance their learning effectively as a kind of self-assesment. During 8 week simulation teaching, 26 pre-service teachers kept individual journal writing and the meta-analysis activities were implemented twice (after the 3rd and 8th week). Right after the first meta-analysis, the pre-service teachers' productive reflection increased clearly. However this would not guarantee the effect would last long time period. By analyzing 8 week reflective journals, reports on meta-analysis activities and small group interview, this study shed light on practical ways of enhancing reflective teacher education.

Meta-Analysis on the Effects of Action Observation Training on Stroke Patients' Walking; Focused on Domestic Research (뇌졸중 환자의 동작관찰훈련이 보행에 미치는 효과에 대한 메타분석; 국내연구를 중심으로)

  • Lee, Jeongwoo;Ko, Un;Doo, Yeongtaek
    • Journal of The Korean Society of Integrative Medicine
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    • v.7 no.4
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    • pp.119-130
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    • 2019
  • Purpose : The purpose of this study was to investigate the meta-analysis on the effects of action observation training on stroke patients' walking. Methods : Domestic databases (DBpia, KISS, NDSL, and RISS) were searched for studies that conducted randomized controlled trials (RCTs) associated with action observation training in adults after stroke. The search outcomes were items associated with the walking function. The 18 studies that were included in the study were analyzed using R meta-analysis. A random-effect model was used for the analysis of the effect size because of the significant heterogeneity among the studies. Sub-group and meta-regression analysis were also used. Egger's regression test was conducted to analyze the publishing bias. Cumulative meta-analysis and sensitivity analysis were also done to analyze a data error. Results : The mean effect size was 2.77. The sub-group analysis showed a statistical difference in the number of training sessions per week. No statistically significant difference was found in the meta-regression analysis. Publishing bias was found in the data, but the results of the trim-and-fill method showed that such bias did not affect the obtained data. Also, the cumulative meta-analysis and sensitivity analysis showed no data errors. Conclusion : The meta-analysis of the studies that conducted randomized clinical trials revealed that action observation training effectively improved walking of the chronic stroke patients.

Alcohol Intake and Risk of Thyroid Cancer: A Meta-Analysis of Observational Studies

  • Hong, Seung-Hee;Myung, Seung-Kwon;Kim, Hyeon Suk;The Korean Meta-Analysis (KORMA) Study Group
    • Cancer Research and Treatment
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    • v.49 no.2
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    • pp.534-547
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    • 2017
  • Purpose The purpose of this study was to assess whether alcohol intake is associated with the risk of thyroid cancer by a meta-analysis of observational studies. Materials and Methods We searched PubMed and EMBASE in June of 2015 to locate eligible studies. We included observational studies such as cross-sectional studies, case-control studies, and cohort studies reporting odd ratios (ORs) or relative risk (RRs) with 95% confidence intervals (CIs). Results We included 33 observational studies with two cross-sectional studies, 20 case-controls studies, and 11 cohort studies, which involved a total of 7,725 thyroid cancer patients and 3,113,679 participants without thyroid cancer in the final analysis. In the fixed-effect model meta-analysis of all 33 studies, we found that alcohol intake was consistently associated with a decreased risk of thyroid cancer (OR or RR, 0.74; 95% CI, 0.67 to 0.83; $I^2=38.6%$). In the subgroup meta-analysis by type of study, alcohol intake also decreased the risk of thyroid cancer in both case-control studies (OR, 0.77; 95% CI, 0.65 to 0.92; $I^2=29.5%$; n=20) and cohort studies (RR, 0.70; 95% CI, 0.60 to 0.82; $I^2=0%$; n=11). Moreover, subgroup meta-analyses by type of thyroid cancer, gender, amount of alcohol consumed, and methodological quality of study showed that alcohol intake was significantly associated with a decreased risk of thyroid cancer. Conclusion The current meta-analysis of observational studies found that, unlike most of other types of cancer, alcohol intake decreased the risk of thyroid cancer.

A Meta-analysis of the Relationship between Mediator Factors and Purchasing Intention in E-commerce Studies

  • Nam, Soo-Tai;Jin, Chan-Yong;Sim, Jaesung
    • Journal of information and communication convergence engineering
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    • v.12 no.4
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    • pp.257-262
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    • 2014
  • Meta-analysis is a statistical integration method that delivers an opportunity to overview the entire result by integrating and analyzing many quantitative research results. This study will find meaningful mediator variables for criterion variables that affect purchase and repurchase intentions in e-commerce, on the basis of the results of a meta-analysis. We reviewed a total of 114 e-commerce studies published in Korean journals between 2000 and 2014, where a cause and effect relationship is established between variables that are specified in the conceptual model of this study. In this meta-analysis, the path between trust and purchase intention showed the biggest effect size. The second biggest effect size was found in the path between commitment and purchase intention, while the smallest one was obtained with perceived. Thus, we present the theoretical and practical implications of these results and discuss the differences among these results through a comparative analysis with previous studies.

A genome-wide association study of reproduction traits in four pig populations with different genetic backgrounds

  • Jiang, Yao;Tang, Shaoqing;Xiao, Wei;Yun, Peng;Ding, Xiangdong
    • Asian-Australasian Journal of Animal Sciences
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    • v.33 no.9
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    • pp.1400-1410
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    • 2020
  • Objective: Genome-wide association study and two meta-analysis based on GWAS performed to explore the genetic mechanism underlying variation in pig number born alive (NBA) and total number born (TNB). Methods: Single trait GWAS and two meta-analysis (single-trait meta analysis and multi-trait meta analysis) were used in our study for NBA and TNB on 3,121 Yorkshires from 4 populations, including three different American Yorkshire populations (n = 2,247) and one British Yorkshire populations (n = 874). Results: The result of single trait GWAS showed that no significant associated single nucleotide polymorphisms (SNPs) were identified. Using single-trait meta analysis and multi-trait meta analysis within populations, 11 significant loci were identified associated with target traits. Spindlin 1, vascular endothelial growth factor A, forkhead box Q1, msh homeobox 1, and LHFPL tetraspan submily member 3 are five functionally plausible candidate genes for NBA and TNB. Compared to the single population GWAS, single-trait Meta analysis can improve the detection power to identify SNPs by integrating information of multiple populations. The multiple-trait analysis reduced the power to detect trait-specific loci but enhanced the power to identify the common loci across traits. Conclusion: In total, our findings identified novel genes to be validated as candidates for NBA and TNB in pigs. Also, it enabled us to enlarge population size by including multiple populations with different genetic backgrounds and increase the power of GWAS by using meta analysis.

Lack of Association Between the CYP1A1 Ile462Val Polymorphism and Endometrial Cancer Risk: a Meta-analysis

  • Wang, Xi-Wen;Zhong, Tian-Yu;Xiong, Yun-Hui;Lin, Hai-Bo;Liu, Qing-Yi
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.8
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    • pp.3717-3721
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    • 2012
  • Purpose: Any association between the CYP1A1 Ile462Val polymorphism and endometrial cancer risk remains inconclusive. For a more precise estimate, we performed the present meta-analysis. Methods: PUBMED, OVID and EMBASE were searched for the studies which met inclusion criteria. Data in all eligible studies were evaluated and extracted by two authors independently. The meta-analysis estimated pooled odds ratio (OR) with 95% confidence interval (CI) for endometrial cancer risk attributable to the CYP1A1 Ile462Val polymorphism. Results: A total of 7 studies were included in this meta-analysis. The results indicated no association between endometrial cancer risk and the CYP1A1 Ile462Val polymorphism (for Val vs Ile allele model [OR 1.09, 95% CI 0.73-1.62]; for Val.Val vs Ile.Ile genotype model [OR 1.54, 95% CI 0.56-4.23]; for (Ile.Val + Val.Val) vs Ile.Ile genotpye model [OR 1.08, 95% CI 0.71-1.63]; for Val.Val vs (Ile.Ile + Ile.Val) genotype model [OR 1.46, 95% CI 0.53-4.04]). Conclusions: This meta-analysis suggests that there is no association between endometrial cancer risk and the CYP1A1 Ile462Val polymorphism.