• Title, Summary, Keyword: Vitamin E

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Assessment of Vitamin E Status of Female Nursing-Home Residents (양로원 거주 여자 노인들의 비타민 E 섭취 상태 조사)

  • Kim, Hee-Seon;Kim, Ji-Sun;Song, Rha-Yun
    • Korean Journal of Human Ecology
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    • v.10 no.4
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    • pp.411-419
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    • 2001
  • This study was peformed to assess the nutritional status of female nursing home residents by dietary intake. The subjects were 60 nursing home residents aged over 60 from 3 different nursing homes in Seoul, Cheonan and Chunchon. Dietary intake was assessed by 24-hr recall and nutrient intake was calculated using CAN-Pro and database for vitamin E established by authors. To establish vitamin E database, we analyzed vitamin E concentration using HPLC in several foods consumed frequently by nursing home residents. The results of nutrient intake were as follows; 1) Average daily intakes of energy, protein, phosphorous, iron, vitamin $B_1$ and niacin were higher than RDA, but calcium, vitamin $B_2$ and niacin of Chunchon were lower than RDA. 2) Intakes of protein, sodium and niacin of Cheonan residents were significantly higher than those of Seoul. 3) Intakes of phosphorous, potassium, vitamin $B_1$ and dietary fiber of Cheonan residents were significantly higher than Seoul and Chunchon. 4) Intakes of sodium and cholesterol of Seoul residents were higher than Cheonan and Chunchon. 5) Average daily intake of vitamin E was lower than RDA. Especially vitamin A intake of Cheonan residents was significantly lower than other two cities.

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Effects of Vitamin E and Selenium on the Antioxidative Defense System in Streptozotocin-induced Diabetic Rats (Vitamin E와 Selenium이 Streptozotocin 유발 당뇨쥐의 항산화계에 미치는 영향)

  • 이순재
    • Journal of Nutrition and Health
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    • v.29 no.1
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    • pp.22-31
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    • 1996
  • The purpose of this study was to investigate the effect of vitamin E and selenium on the antioxidative defense mechanism in the liver of streptozotocin(STZ)-induced diabetic rats. Sprague-Dawley male rats(120$\pm$10gm) were randomly assigned to one control and five STZ-diabetic groups. Diabetic groups were classified to STZ-0E (vitamin E free diet), STZ-40E(40mg vitamin E/kg of diet), STZ-400E(400mg vitamin E/kg of diet), STZ-S(0.5ppm Se/kg of diet) and STZ-400ES(400mg vitamin E and 0.5ppm Se/kg of diet) according to the level of vitamin E and selenium supplementation. Diabetes was experimentally induced by intravenous adminstration of 55mg/kg of STZ in citrate buffer(pH 4.3) after 4-weeks feedng of six experimental diets. Animals were sacrificed at the 4th day of diabetic states. Activities of the serum glutamic oxaloacetate transaminase(GOT) and the glutaminc pyruvate transaminase(GPT) in STZ-0E, STZ-40E and STZ-S rats were higher than those of control. Liver xanthine oxidase activities were similar to serum GOT and GPT. Liver superoxide dismutase(SOD) activities were higher in STZ-0E and STZ-40E groups by 33%, 22%, respectively than that of control. Glutathione S-transferase(GST) activities of liver were similar to GSH-Px activities. The contents of vitamin E in liver tissue were significantly lower STZ-0E, STZ-40E and STZ-S groups by 50%, 36%, 45% than that of control. Reduced glutathione(GSH) contents of liver were lower STZ-0E, STZ-40E, STZ-400E, STZ-S and STZ-400ES groups by 57%, 51%, 19%, 18%, 12% than that of control. Lipid peroxide values (LPO) in liver were higher 5.6, 2.3 and 2.3 times in STZ-0E, STZ-40E and STZ-S group than that of control. The present results indicate that STZ-induced diabetic rats are more sensitive to oxidative stress, leading to the acceleration of lipid peroxidation process, which can be more accelerated by feeding the low level of dietary vitamin E. In the coincident supplementation of high dietary vitamin E and selenium antioxidative enzymes activities and physiolosical antioxidants were increased more than those of the separate supplementation of vitamin E or selenium. Therefore, dietary vitamin E and selenium reduced peroxidative damage of tissue, promoting antioxidative defense mechanism against lipid peroxidation by diabetes.

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Effects of Dietary Vitamin E and Selenium on Hematopoiesis and Antioxidative Detoxification Mechanism in Lead Poisoned Rats (식이 Vitamin E와 Selenium이 납중독된 흰쥐에 있어서 조혈작용과 항산화적 해독기구에 미치는 영향)

  • 이순재;박규영;김관유
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.22 no.6
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    • pp.651-657
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    • 1993
  • The protective effects of dietary vatamin E and selenium on peroxidative damage and hematopoietic inhibition by lead poisoning were investigated in rats. Male Sprague-Dawley rats weighing 150$\pm$5g were divided into six groups according to dietary vitamin E and / or selenium levels, i.e. control(vitamin E, 40mg/kg diet), 0E(without vitamin E, Se), 40E(vitamin E, 40mg/kg diet ; without Se), 200E(vitamin E, 200mg/kg diet ; without Se), 200ES(vitamin E, 200mg/kg diet ; Se, 0.5ppm) and 0Es(without vitamin E ; Se, 0.5ppm) groups. All experimental groups were fed ad libitum 2000ppm lead in diet except control for 4 weeks. Hemoglobin contents and hematocrit values of lead groups were lower than control group except 200ES group and were the lowest in 0E group. Aminolevulinic acid dehydratase(ALAD) activities of blood and liver were sequentially reduced in 200ES, 200E, 0ES, 40E and 0E groups, compared to control, were as urinary aminolevulinic acid (ALA) excretions were increased in the groups which represented low ALAD activity. Heapatic superoxide dismutase(SOD) activities was lower in 0E, and higher in 40E, 200E and 200ES groups, compared with control. Glutathione peroxidase(GPX) activities of liver were reduced in 0E and 40E groups, but those of 0ES, 200E and 200ES groups were significantly increased. Especially GPX activities in 200ES and 200ES groups were not different from control group. The reduced glutathione contents in liver were lowest in 0E and 40E groups, compared with control, whereas levels of the oxidized form were opposite phenomena of that. Liver lipid peroxide values of 0E, 0ES, 40E and 200E groups were 6.4, 2.9, 2.1 and 1.3 fold higher than control, respectively, but 200ES groups was not different from control.

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Effect of Vitamin E Treatments on The Humoral and Cellular Immune Responses in Mice. - Animal experiment for nursing care of vitamin E-deficient patients- (비타민 E 투여가 마우스의 체액성 및 세포성 면역반응에 미치는 영향 -비타민 E 결핍환자의 간호중재 개발을 위한 동물실험 -)

  • 김금재
    • Journal of Korean Academy of Nursing
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    • v.23 no.4
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    • pp.528-543
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    • 1993
  • Vitamin E, which has its advocates in the treatment of diabetes mellitus. autoimmune disease, cancer and peripheral vascular and thromboembolic disease, has now been alleged to have a powerful antioxident effect and to affect various biological activities such as fertility factor, inhibition of human platelet aggregation and stabilization of biological membranes. The present study was designed to test whether vitamin I(alpha-tocopherol) can : (1) enhance the hemagglutinin response to sheep red blood cells (SRBC), (2) modulate Arthus and delayed type hypersensitivity(DTH) to SRBC and contact hypersensitivity to dinitrofluorobenzene (DNFB). (3) enhance the mitogenic response of murine splenocyte, (4) decrease the recovery of Cryptococcus neoformans from brain, lung, liver, spleen and kidney of infected mice and (5) have an inhibitory or enhancing effect on the induction of active systemic anaphylaxis(ASA) induced by chicken-gamma globulin (CGG) in mice. Mice were given either intramuscular injections of 0.3ml (300mg) of vitamin I before immunization or were infection for 10 consecutive days or were given by vitamin I esophageal intubation, 0.1ml(100mg), for 20 days before sacrifice for the mitogenic response experiments. It was found that vitamin E treated mice showed a significant enhancement in hemagglutinin response, Arthus reaction and DTH to SRBC and contact hypersensitivity to DNFB. There was no significant difference in the mitogenic response to phytohemagglutinin(PHA), but the response to concanavalin A(ConA) or pokeweed mitogem(PWM) was increased in vitamin E-treated mice. Interestingly, the vitamin E administration before C. neoformans infection decreased significantly the recovery of C. neoformans from brain lung, liver, spleen and kidney of the infected mice as compared with that of the control mice, strongly suggesting that vitamin E pretreatment may increase the resistance of mice to the fungal infection. Unexpectedly, vitamin E administration enhanced the production of CGG -induced ASA. Taken together, it can be concluded that vitamin I administration may in-crease the humoral and cellular immune response and resistance. to C. neoformans infection, but enhance the induction of ASA to CGG. Further studies are necessary to clarify the underlying mechanism accounting for these effects.

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Effects of Dietary Lycopene and Vitamin E on Egg Production, Antioxidant Status and Cholesterol Levels in Japanese Quail

  • Sahin, N.;Sahin, K.;Onderci, M.;Karatepe, M.;Smith, M.O.;Kucuk, O.
    • Asian-Australasian Journal of Animal Sciences
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    • v.19 no.2
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    • pp.224-230
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    • 2006
  • Japanese Quails were used to evaluate the effects of dietary supplementation with vitamin E (dl-a-tocopheryl-acetate), lycopene, and their combination on egg production, egg quality, concentrations of malondialdehyde (MDA), vitamin E, A and cholesterol in serum and egg yolk. Quails (n = 120; 55 d old) were divided into four groups (n = 30/group) and fed a basal diet or the basal diet supplemented with lycopene (100 mg/kg diet), vitamin E (250 mg dl-${\alpha}$-tocopheryl-acetate/kg diet) or a combination of lycopene and vitamin E (100 mg/kg lycopene plus 250 mg dl-${\alpha}$-tocopheryl-acetate/kg diet). Vitamin E and lycopene did not affect (p>0.05) body weight, feed intake or egg weight. Egg production and Haugh unit were greater (p<0.05) in each supplemental group compared with the control group (p<0.05). Serum and liver MDA levels were decreased in supplemented groups compared with the control group. Separately or as a combination, supplemental lycopene and vitamin E increased serum and egg yolk vitamin E and A but decreased cholesterol concentrations (p<0.05). In general, when a significant effect was found for a parameter, the magnitude of the responses to vitamin and lycopene supplements was greatest with the combination of the lycopene and vitamin E, rather than that observed with each supplement separately. Results of the present study indicate that supplementing with a combination of dietary lycopene and vitamin E reduced serum and yolk cholesterol concentrations and improved antioxidant status.

Effects of Vitamin E on the Microsomal Mixed Function Oxidase System of Kidney in Streptozotocin-induced Diabetic Rats (식이 Vitamin E가 Streptozotocin 유발 당뇨쥐 신장조직에서의 Microsomal Mixed Function Oxidase System에 미치는 영향)

  • 신주영
    • Journal of Nutrition and Health
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    • v.33 no.6
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    • pp.619-624
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    • 2000
  • The purpose of this study was to investigate the effects of vitamin E on microsomal mixed function oxidase system of kidney in streptozotocin(STZ) induced diabetic rats. Sprague-Dawley male rats weighing 140$\pm$10g were randomly assigned to one control and three STZ-diabetic groups which were subdivided into vitamin E free diet(DM-0E group) 40mg vitamin E per kg diet(DM-40E group) and 400mg vitamin E per kg diet(DM-400E group). Vitamin E level of normal group was 40 mg per kg diet. Diabetes was experimentally induced by intravenous administration of 55 mg/kg B.W of STZ in citrate buffer(pH4.3) after 4 weeks feeding of experimental diets. Animals were sacrificed at the 6th day of diabetic state. The contents of cytochrome P450 in kidney were increased by 82, 54, 41% in DM-0E, DM-40E and DM-400E groups respectively when compared with normal group. The contents of cytochrome b5 in kidney were increased by 28% in DM-0E when compared with normal group but those of DM-40E and DM-400E groups were similar to that of normal group. The activities of NADPH-cytochrome P450 reductase in kidney that were increased by 35% in DM-0E group. Levels of TBARS(thiobarbituric acid reactive substance) in kidney were increased by 207, 129% and 72% in DM-0E and DM-400E groups respectively when compared with normal group but those of DM-40E and DM-400E groups were 26,44% lower than that of DM-0E groups. It is know that the activities of MFO system and lipid peroxidation were inhibited in kidney of STZ-induced diabetic rat by administeration of high doses of vitamin E.(Korean J Nutrition 33(6) : 619~624, 2000)

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Effects of Vitamins C and E on Hepatic Drug Metabolizing Function in Nypoxia/Reoxygenation (저산소 및 산소재도입시 vitamin C와 E가 간장 약물대사 기능에 미치는 영향)

  • 윤기욱;이상호;이선미
    • YAKHAK HOEJI
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    • v.44 no.3
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    • pp.237-244
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    • 2000
  • Liver isolated from 18 hours fasted rats was subjected to $N_2$hypoxia (for 45 min) followed by reoxygenation (for 30 min). The perfusion medium used was Krebs-Henseleit bicarbonate buffer (pH 7.4, $37^{\circ}C$). Vitamin C (0.5 mM) and trolox C (0.5 mM), soluble vitamin E analog, were added to perfusate. Lactate dehydrogenase (LDH), total glutathione, oxidized glutathione, lipid peroxide and drug-metabolizing enzymes were measured. After hypoxia LDH significantly increased but this increase was attenuated by vitamin C and combination of vitamin C and E. Total glutathione and oxidized glutathione in perfusate markedly increased during hypoxia and this increase was inhibited by vitamins C, E and its combination. Similarly; oxidized glutathione and lipid peroxide in liver tissue increased after hypoxia and reoxygenation and this increase was inhibited by vitamin I and combination of vitamin C and E. Hepatic drug metabolizing function (phase I, II) were suppressed during hypoxia but improved during reoxygenation. While vitamins C and E only increased glucuronidation, the combination of vitamin C and E increased the oxidation, glucuronidation and sulfation. Our findings suggest that vitamins C and E synergistically ameliorates hepatocellular damage as indicated by abnormalities in drug metabolizing function during hypoxia/reoxygenation and that this protection is in major part, caused by decreased oxidative stress.

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A Study on Vitamin A and E Content in Commercially Processed Products - Beverage, Cereal, Snack, Other Cocoa, Sugar and Chocolate Processed Products - (시판 가공식품의 비타민 A, E 함량 조사 연구 - 음료수, 시리얼, 과자, 기타코코아·당류·초콜릿가공품 등을 중심으로 -)

  • Jeong, Da-un;Lee, Heon-Ok;Kim, Young-Kyoung;Om, Ae-Son
    • Korean journal of food and cookery science
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    • v.32 no.6
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    • pp.811-817
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    • 2016
  • Purpose: People have long been interested about antioxidant nutrients such as vitamin A and E to stay in healthy states. This present study provides trustworthy nutritional information and evaluates vitamin A and E contents in emphasized food items. Methods: Vitamin A or vitamin E emphasized foods including beverage, cereal, snack, chocolate product, other cocoa products, and sugar products were analyzed. The contents of vitamin A, E in samples were examined by high performance liquid chromatography. Vitamin A and vitamin E contents were compared with the labeled value indicated on the nutrition label. Results: Vitamin A (n=18) value ranged from 90% to 248% and vitamin E (n=20) value ranged between 96-413% of labeled value. Analyzed samples ranged more than 80% of the labeled value, which complied with food labeling rules. Conclusion: Providing accurate information for nutrition label is essential to confirm nutrient contents in foods. It will help to decide the adequate level of nutrient intake. Therefore, the nutrition labeling system should be supervised continuously with regular monitoring analysis.

The Effect of Hyaluronic Acid and Vitamin I Combination on Preventing Postoperative Intraperitoneal Adhesion Formation in Dogs (개에서 Hyaluronic Acid와 Vitamin E의 병용이 복강수술 후 유착방지에 미치는 효과)

  • Bae, Jae-Sung;Jang, Kwang-Ho;Kwon, Young-Sam;Jang, Hwan-Soo;Kim, Jung-Eun;Park, Se-Il;Lim, Jae-Hyun;Li, Wen-Xue;Lee, Seoung-Jin
    • Journal of Veterinary Clinics
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    • v.20 no.1
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    • pp.42-48
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    • 2003
  • This study was performed to compare the effect of hyaluronic acid(HA), vitamin I and their combinations for the prevention of postoperative intraperitioneal adhesion in dogs. Twelve mongrel dogs were divided into four groups; HA- (HA Group), vitamin E 800IU- (E8 Group), HA + vitamin E 800IU- (HA+E8 Group) and HA + vitamin E 1600IU-treated group(HA+E16 Group) with three dogs in each group. After celiotomy, five abrasions of 1$\times$1 cm area were made on the antimesenteric serosal surface of the anterior ileocecum with a No. 10 scalpel blade. The five abrasions and peritoneal cavity were coated with 25 of 0.l% HA. Oral supplements of vitamin E were given from the fifth day before the operation to the fourteenth day after the operation. Hematologic values were evaluated before the operation and on the 1st, 4th, 7th and 14th day after the operation. The locations and scores of adhesion were assessed through the second operation on the 21st day after the first operation. The adhesions were located on serosa to mesentary(43.3%)), serosa to serosa(20%), serosa to omentum(5%) and serosa to parietal peritoneum(1.7%). The incidences of adhesion in HA, E8, HA+E8 and HA+E16 groups were 80%, 100%, 47% and 53%, respectively. The scores of adhesion in HA+E8 group(p < 0.05) were lower than those in other groups. This study showed that the combination of HA and vitamin E 800IU was significantly effective in reducing the intraperitoneal adhesion in dogs.

Improvement effect of formula containing Vitamin A and Vitamin E on the Strech mark (VitaminA와 VitaminE 함유 제제의 Strech mark 개선효과)

  • Kim, Yang-Ho
    • Journal of the Korean Society of Fashion and Beauty
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    • v.2 no.3
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    • pp.36-43
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    • 2004
  • This is a research on the effect of formula containing of vitamin A and vitamin E(Frie of oil, Wlter Bouhon GmBH, Germany) on the strech mark. The participants of this study were 20 women at the age of early 20s through middle 20s, who had strech marks that had been over 1 year at the minimum and at less than 5 years at the maximum. Formula containing of vitamin A and vitamin E was applied with typical massage to strech marks for 4 months and twice per day. Improvement resulting from the application was evaluated through observation with the naked eye, questionnaire survey, and the equipment used was DermaScan C Ver3(Cortex Technology, Denmark). The experiment showed that parts cared with formula containing of vitamin A and vitamin E had less strech marks than those control site(treated with jojoba oil).In around 2 months since the use of the formula containing of vitamin A and vitamin E, the tensile of the skin increased and deep wrinkles on the chapped surface became unclear, and in around 4 months the tensile force again decreased and the resilience of the skin increased, and the ultrasonic image showed the decrease of echo pore-zone, which indicates the degree of tissue damage. According to the result of the questionnaire survey, strech marks of less than red strech marks of primary stage were improved more quickly than white strech marks and all participants appeared to experience improvement. The result shows that if this formula is used continuously over 4 months, it reduces strech marks and increase the resilience of the skin. It is considered necessary to continue objective measuring and research concerning strech marks.

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