• Title, Summary, Keyword: Viscum album

Search Result 106, Processing Time 0.027 seconds

Antimicrobial Effect of Rubia akane Nakai Extract on Food-Borne Pathogens (식중독유발 세균의 증식에 미치는 천초근 추출물의 영향)

  • Bae, Ji-Hyun;Jang, Hye-Jung;Jung, Jung-Im
    • Journal of the Korean Society of Food Science and Nutrition
    • /
    • v.34 no.3
    • /
    • pp.389-394
    • /
    • 2005
  • This study was performed to investigate the antimicrobial activity of the Rubia akane Nakai extract against food-borne pathogens. First, the Rubia akane Nakai was extracted with methanol at room temperature and the fractionation of the methanol extract was carried out by using petroleum ether, chloroform, and ethyl acetate, and methanol. The antimicrobial activity of the Rubia akane Nakai extract was determined by using a paper disc method against food-borne pathogens and food spoilage bacteria. The methanol extract of Rubia akane Nakai showed the highest antimicrobial activity against Bacillus cereus and Pseudomonas aeruginosa. Synergistic antimicrobial effect was observed when Rubia akane Nakai extract was mixed with Viscum album var. coloratum extract as compared to each extract alone. Finally, the growth inhibition curves were determined by using methanol extract of Rubia akane Nakai against Bacillus cereus and Pseudomonas aeruginosa. The methanol extract of Rubia akane Nakai had strong antimicrobial activity against Pseudomonas aeruginosa at the concentration of 4,000 ppm. At this concentration, the growth of Pseudomonas aeruginosa was retarded more than 72 hours and up to 48 hours for Bacillus cereus. From these results, it was concluded that the methanol extract of Rubia akane Nakai inhibited effectively Bacillus cereus and Pseudomonas aeruginosa.

Antioxidant Effects of Viscum album L. Extracts by Extraction Conditions (추출조건에 따른 겨우살이 추출물의 항산화효과)

  • Lee, Hye-Jin;Do, Jeong-Ryong;Kwon, Joong-Ho;Kim, Hyun-Ku
    • Journal of the Korean Society of Food Science and Nutrition
    • /
    • v.39 no.1
    • /
    • pp.14-19
    • /
    • 2010
  • This study was to investigate antioxidant effects of mistletoe extracts by extraction conditions. Electron donating ability of 50% ethanol extract had shown 92.27% at 50 mL/g, which was higher than 1.0% and 0.1% L-ascorbate solutions (p<0.05). SOD-like activities were the most effective in all samples at 50 mL/g, which were barely detectable. The total polyphenol contents of water extracts including all extracts were the highest at 50 mL/g extracts (p<0.05). The nitrite scavenging effects were different depending on pH value; they were decreased overall as pH value was increased. Especially, nitrite scavenging effects were the most effective in pH 1.2, which showed more than 80% (p<0.05). Tyrosinase-inhibitory activities ranged at fewer than 10%. These results indicate that mistletoe extracts are potential sources of natural antioxidant.

Anatomy of the Korean mistletoe and their haustorial features in host plants (한국산 겨우살이과 식물의 형태와 기주별 흡기 특징)

  • Choi, Kyung;Park, Kwang-Woo;Kim, Hyuk-Jin;Lee, Jae-Dong;Koo, Jachoon;Whang, Sung-Soo
    • Korean Journal of Plant Taxonomy
    • /
    • v.39 no.1
    • /
    • pp.4-11
    • /
    • 2009
  • Anatomical features of both leaves and stems of the four mistletoes in Korea (Viscum album var. coloratum, Korthalsella japonica, Loranthus yadoriki, L. tanaka) and of their secondary haustorial structure within several host plants were investigated. Among the four mistletoes, there were diagnostic characters of the anatomy of leaves and stems which enabled us to distinguish the four taxa. Leaves were observed to have three distinct characters including unifacial or bifacial leaves, the number of vascular bundles in the midveins, and the level of development of sclerenchyma cells. There were four diagnostic characters of stems: overall morphology of stems in transverse view, degree of cuticle development, arrangement of vascular bundles, and features of the sclerenchyma and pith. In order to determine secondary haustorial traits, the research focused on the seven host plants of L. yadoriki and on the five host plants of K. japonica. The following features were found to be important: presence or absence of an aerial runner root, the shape of the haustorial strand and flange, the degree of penetration into host tissues, and their development of shaft in transverse view, the development both of secondary haustorial cells and short tracheid in hyphae. Korthalsella japonica and L. yadorki were clearly distinguished by these characters. The secondary haustorial forms in each host were somewhat different, due to varying degrees of development in the strength of the host plants' wood. However, qualitative characters like the final position of the secondary haustorial penetration into host tissues and the development of short tracheid cells were not only affected by the degree of development of the host plants, but also useful for the systematic study.

In vivo Toxicity and Immunoadjuvant Activity of Korean Mistletoe (Viscum album coloratum) Extract Fermented with Lactobacillus (한국산 겨우살이 유산균 발효 추출물의 독성 및 면역증강 효과)

  • Yoon, Taek-Joon;Yang, Woong-Suk;Park, Sung-Min;Jung, Hoe-Yune;Lee, An-Na;Jung, Jin-Hyuk;Kang, Tae-Bong;Yoo, Yung-Choon;Kim, Jong-Bae
    • Korean Journal of Food Science and Technology
    • /
    • v.41 no.5
    • /
    • pp.560-565
    • /
    • 2009
  • In this study, Korean mistletoe extract (KM-110) was fermented with two strains of Lactobacillus (FKM-110) and then toxicity, lectin content, and immune activities were investigated. The lectin content of FKM-110 was about 53-71% lower than that of KM-110. When mice were subcutaneously administered with KM-110 and FKM-110, the $LD_{50}$ obtained for KM-110 treatment was 50-100 mg/kg as compared to 150-200 mg/mL for FKM-110. Each preparation stimulated macrophages directly and enhanced productivity of inflammatory cytokines such as TNF-${\alpha}$ and IL-$1{\beta}$. FKM-110 treatment resulted in lower cytokine production compared to KM-110. When mice were immunized with Keyhol limpet hemocyanin (KLH) antigen along with KM-110 or FKM-110 administration, higher antibody titers to KLH were observed in the KM-110 or FKM-110 groups compared to mice immunized with KLH alone, thereby showing no difference between KM-110 and FKM-110. Therefore, fermentation of Korean mistletoe extract with these Lactobacillus strains decreased toxicity in vivo while the enhancement of immune activity by KM-110 and FKM-110 was similar. These data suggest that KM-110 fermentation tended to decrease lectin content and in vivo toxicity. In addition, other components in the fermented mistletoe extract appear to stimulate immuno-adjuvant activity instead of lectin.

The Immunological Effect of Mistletoe Extract on Gastric Cancer Patients (미슬토 추출물(Mistletoe Extract)이 위암환자의 수술 후 면역기능에 미치는 효과)

  • Yang, Sung-Woo;Shin, Dong-Gue;Kim, Il-Myung;Yoon, Seong-Min;Lee, Yong-Jik;Heo, Su-Hak;Kim, Tae-Hee
    • Journal of Gastric Cancer
    • /
    • v.7 no.3
    • /
    • pp.167-173
    • /
    • 2007
  • Purpose: Mistletoe (Viscum album L.) extract is one of the most widely used agents in alternative cancer therapeutic regimens in Europe. This study was conducted to determine the effect of mistletoe extract on immune function in gastric cancer patients. Materials and Methods: Ten patients that had undergone a curative gastrectomy were enrolled in the prospective study. ABNOBAviscum $Q^{(R)}$ was injected subcutaneously three times a week from postoperative-day 7 to week 16 with an increasing dose. All of the patients simultaneously received chemotheraphy with mitomycin, oral 5-FU and a cisplatin regimen. The WBC count, differential count, lymphocyte/WBC ratio and the level of cytokines (IL-$1{\beta}$, IL-2, IL-6, IFN-$\gamma$, TNF-$\alpha$) were checked in the peripheral blood preoperatively, at postoperative week 8 and at postoperative week 16. Results: The WBC and neutrophil counts significantly decreased after treatment on week 8 and week 16 (P=0.001), but the total eosinophil count was slightly increased (P=0.15). The total lymphocyte count also decreased during treatment but the lymphocyte/WBC ratio was slightly increased without statistical significance (P=0.91). The cytokine levels did not significantly change during treatment. Conclusion: It is somewhat difficult to determine the direct effect of mistletoe therapy on immune function as the effect may be compromised by the concurrent chemotherapy. It can be assumed that the slightly increased lymphocyte/WBC ratio and eosinophil count may be a result of the immunomodulatory effect of the mistletoe extract.

  • PDF

Effects of Water Extract Mixtures from Artemisia capillaris, Camellia sinensis, Schizandra chinensis, and Viscum album var. coloratum on Laying Performance, Egg quality, Blood Characteristics, and Egg Storage Stability in Laying Hens (인진쑥, 녹차, 오미자, 겨우살이 혼합 추출물의 첨가 급여가 산란계의 난 생산성, 계란 품질, 혈액 특성 및 계란 저장성에 미치는 영향)

  • Kim, Dong-Wook;Kim, Ji-Hyuk;Kang, Geun-Ho;Kang, Hwan-Ku;Choi, Ji-Young;Kim, Sang-Ho;Kang, Chang-Won
    • Food Science of Animal Resources
    • /
    • v.30 no.3
    • /
    • pp.449-457
    • /
    • 2010
  • This study investigated the effects of three kinds of water extract mixtures each with different ratios of A. capillaris, C. sinensis, S. chinensis, and V. coloratum on laying performance, egg quality, blood characteristics, and egg storage stability in laying hens. One hundred and sixty 35-wk-old laying hens (Hy-line brown) were divided into four groups of 10 birds each replicated times four. The treatments involved a basal diet (C, control) or diets containing three kinds of water extract mixtures at 200 ppm (T1, water extract mixture A; T2, water extract mixture B; T3, water extract mixture C). The egg production rate, egg mass, and feed conversion ratio were significantly improved in all treatments compared to those of control (p<0.05). Haugh unit and egg yolk color in all treated groups were significantly improved in comparison with control (p<0.05), but no significant differences were observed for egg shell quality. The content of total cholesterol in blood serum was significantly decreased in all treatments compared to that of control (p<0.05). The blood biochemical parameters of liver and kidney damage were significantly decreased in all treatments compared to those of control (p<0.05). Total antioxidant activity in the blood serum of all treated groups was increased as well. The Haugh unit and malondialdehyde content in the egg yolk during storage were significantly decreased in all treated groups compared to control (p<0.05). Consequently, the dietary supplementation of water extract mixtures of A. capillaris, C. sinensis, S. chinensis, and V. coloratum improved laying performance and egg quality but decreased egg quality deterioration with increased storage. These results suggest that medicinal plant extracts could be used as a feed additive in feed for laying hens.