• Title, Summary, Keyword: UV (ultraviolet) light

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Glycation Inhibitory and Antioxidative Activities of Ergothioneine (에르고티오네인의 당화 억제 및 항산화 활성에 관한 연구)

  • Bae, Jun-Tae;Lee, Chung-Hee;Lee, Geun-Soo;Kim, Jin-Hwa;Hong, Jin-Tae
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.45 no.2
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    • pp.151-159
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    • 2019
  • Ergothioneine has been known as an excellent antioxidant and a cellular protector against oxidative damage in vivo. In the present study, ergothioneine was demonstrated to possess antioxidant and anti-glycation activities. The radical scavenging activity of ergothioneine enhanced the viability of human dermal fibroblasts (HDFs) exposed to ultraviolet (UV) light. The UVA irradiation increased the proportion of senescence-associated ${\beta}$-galactosidase (SA-${\beta}$-gal) positive cells in comparison with the normal control group. The treatment of UVA-irradiated HDFs with ergothioneine decreased the level of SA-b-gal (by approximately 45% at an ergothioneine concentration of $400{\mu}M$) compared with the UVA-irradiated HDFs. We also found that ergothioneine inhibited production of glyceraldehyde-derived advanced glycation endproducts (AGEs) in a concentration-dependent manner. The ergothioneine educed carboxymethyl-lysine (CML) expression in comparison to the glyoxal treatment. In addition, in the Western blot analysis, treatment of glyoxal-stimulated HDFs with ergothioneine resulted in a dose-dependent decrease in the expression level of the receptor for AGE (RAGE). These results suggest that ergothioneine may have potent anti-aging effects and could be used as a cosmetic material against cellular accumulation of AGEs.

Degradation Pattern of Propanil (3',4'-dichloropropionanilide) as affected by Environmental Condition of Solution (Propanil (3',4'-dichloropropionanilide)의 용액중(溶液中) 환경조건(環境條件)에 따른 분해양상(分解樣相))

  • Shin, Yun Gyo;Kim, Jang Eok;Hong, Jong Uck
    • Current Research on Agriculture and Life Sciences
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    • v.5
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    • pp.33-39
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    • 1987
  • In order to study the degradation pattern of propanil in solution, the environmental factors such as temperature, pH and UV irradiation effect on propanil degradation were investigated. The degradation of propanil in solution was more rapid in high temperature than in low. The production amount of DCA was increased in high temperature, and then was decreased in a certain period of time because of conversion to TCAB, but the concentration of TCAB was maintained without more degradation. Propanil was rapidly hydrolyzed in alkaline solution as well as in strong acidic solution. Degradation product, DCA was rapidly produced and condensed to TCAB in strong acidic and alkaline condition. On exposur to ultraviolet light, 90% of original propanil was degraded within 20minutes, 0.3 ppm of DCA was produced in 10 minutes, and maintained the concentration throughout irradiation times.

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Preparation and Properties of Phytosphingosine Ascorbate with Retaining Skin Development Effects (피부 활성을 갖는 Phytosphingosine Ascorbate의 합성)

  • Min, Seok-Kee;Jin, Yong-Hoon;Park, Woo-Jung;Eom, Sang-Yong;Kim, Jong-Heon
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.30 no.2
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    • pp.167-172
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    • 2004
  • In the human skin, vitamin C (L -ascorbic acid) that is well known as the activated materials has effects that is skin anti-aging and wrinkle repair by giving impetus to collagen biosynthesis and anti-oxidation, and that is the sun screen, a wound recovering, inhibition melanogenesis and so on. In spite of its effects, vitamin C has the defects of the skin stimulation and easily oxidized instability by water, air, heat and light. For solving their matters, many investigation is advanced and its results are synthesized the various vitamin C derivatives. And yet they have not solved the unstable property of vitamin C and were still insufficient for the comparing with the effect of the pure vitamin C itself. In this study, in order to prepare vitamin C derivative of being improved the stability and to apply vitamin C effect in the skin, we prepared new vitamin C derivative, phytosphingosine ascorbate, by using phytosphingosine, one of sphingolipids, which have a distinguished skin affinity. Phytosphingosine ascorbate can be prepared as the ionic bond between amine group (-NH$_2$) of phytosphingosine and hydroxy group (-OH) of vitamin C by way of the relatively simple reaction. So the structure and properties of the synthesized phytosphingosine ascorbate was confirmed the use of elemental analysis (C 58.3 : H 9.3 : N 2.8 : O 29.5), MALDI TOF-MS (Mw=492.58), Ultraviolet spectra (268.5nm), lH NMR, FT-IR spectra, thermal analysis (m.p=l54$^{\circ}C$), HPLC and so on. And we could confirm the anti-bacterial and anti-oxidation effects. Based on these results, we could confirm to prepare a new material that was expected of both effects of vitamin C and phytosphingosine and that is improved properties of vitamin C.

Photocatalytic disinfection of indoor suspended microorganisms (Escherichia coli and Bacillus subtilis spore) with ultraviolet light (광촉매와 UVA에 의한 실내 부유 미생물(E. coli 및 Bacillus. subtilis sp.) 살균 제거 연구)

  • Yoon, Young H.;Nam, Sook-Hyun;Joo, Jin-Chul;Ahn, Ho-Sang
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.15 no.2
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    • pp.1204-1210
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    • 2014
  • New control methods are proposed for indoor air quality by removing fine airborne dust-particles. As suspended fine dust-particles contain inorganic dust as well as fine organic bacteria, studies for simultaneous control of these contaminants are required. In this study, photocatalytic disinfection of indoor suspended microorganisms such as E. coli and Bacillus subtilis is performed by three types of photocatalysts with UVA irradiation. The UVA irradiation strength was controlled to the minimum $3{\mu}W/cm^2$, and ZnO, $TiO_2$, and ZnO/Laponite ball were used as the catalysts. The results indicate that E. coli was removed over 80 % after about 2 hours of reaction with UVA and all three types of photocatalysts, whereas only with UVA, around 50 % E. coli removal was obtained. Among the catalysts, ZnO/Laponite composite ball was found to have similar sterilizing capacity to $TiO_2$. However, in case of B. subtilis, which has thick cell wall in its spore state, disinfection was not effective under the low UVA irradiation condition, even with the catalysts. Further studies need to figure out the optimal UVA irradiation ranges as well as photocatalysts doses to control airborne dust, to provide healthy clean air environment.