• Title, Summary, Keyword: TSC

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3GPP GERAN Evolution System Employing High Order Modulation and Turbo Coding: TSC for Channel Estimation (터보코딩 및 고차변조를 적용하는 3GPP GERAN 진화 시스템: 채널 추정을 위한 TSC)

  • Lee, Jong-Hwan;Hwang, Eun-Sun;Choi, Byoung-Jo;Hwang, Seung-Hoon;Choi, Jong-Soo
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.33 no.6A
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    • pp.599-606
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    • 2008
  • In this paper, the channel estimation performance of proposed TSC (TSC-S) is investigated in terms of the BER and BLER performances when HSR is considered for GERAN evolution system. The performance is evaluated by the link level simulation and is compared with the other TSC proposal (TSC-E). Numerical results show that the performance employing the TSC-S is almost same to that using the TSC-E. In the case of cochannel interferences, the similar tendency is shown, when joint least square is adopted for channel estimation.

Mammalian target of rapamycin inhibitors for treatment in tuberous sclerosis

  • Kim, Won-Seop
    • Clinical and Experimental Pediatrics
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    • v.54 no.6
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    • pp.241-245
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    • 2011
  • Tuberous sclerosis complex (TSC) is a genetic multisystem disorder that results from mutations in the TSC1 or TSC2 genes, and is associated with hamartomas in several organs, including subependymal giant cell tumors. The neurological manifestations of TSC are particularly challenging and include infantile spasms, intractable epilepsy, cognitive disabilities, and autism. The TSC1- and TSC2-encoded proteins modulate cell function via the mammalian target of rapamycin (mTOR) signaling cascade, and are key factors in the regulation of cell growth and proliferation. The mTOR pathway provides an intersection for an intricate network of protein cascades that respond to cellular nutrition, energy levels, and growth factor stimulation. In the brain, TSC1 and TSC2 have been implicated in cell body size, dendritic arborization, axonal outgrowth and targeting, neuronal migration, cortical lamination, and spine formation. The mTOR pathway represents a logical candidate for drug targeting, because mTOR regulates multiple cellular functions that may contribute to epileptogenesis, including protein synthesis, cell growth and proliferation, and synaptic plasticity. Antagonism of the mTOR pathway with rapamycin and related compounds may provide new therapeutic options for TSC patients.

Two cases of TSC2/PKD1 contiguous gene deletion syndrome

  • You, Jihye;Kang, Eungu;Kim, Yoonmyung;Lee, Beom Hee;Ko, Tae-Sung;Kim, Gu-Hwan;Choi, Jin-Ho;Yoo, Han-Wook
    • Journal of Genetic Medicine
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    • v.13 no.1
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    • pp.36-40
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    • 2016
  • Tuberous sclerosis complex (TSC, MIM#191100) is an autosomal dominant neurocutaneous syndrome caused by mutation or deletion of TSC1 encoding hamartin or TSC2 encoding tuberin and characterized by seizure, mental retardation, and multiple hamartomas or benign tumors in the skin, brain, retina, heart, kidney, and lungs. The TSC2 gene on chromosome 16p13.3 lies adjacent to the PKD1 gene which is responsible for autosomal dominant polycystic kidney disease (MIM#173900). The TSC2/PKD1 contiguous gene syndrome (TSC2/PKD1 CGDS, MIM#600273) is caused by deletion of both TSC2 and PKD1 gene. We recently experienced a 15 month-old boy and a 26 month-old girl with TSC2/PKD1 CGDS confirmed by multiplex ligation-dependent probe amplification (MLPA) analysis. They showed not only typical neurologic manifestations of TSC such as epilepsy, subependymal nodules, and subcortical tubers, but also polycystic kidney disease. The contiguous gene syndrome involving PKD1 and TSC2 should be suspected in children with enlarged polycystic kidneys and TSC. MLPA analysis is a useful method for the genetic confirmation of TSC2/PKD1 CGDS.

Association between perioperative cholesterol level and analgesia after video-assisted thoracoscopic surgery

  • Oh, Tak Kyu;Kim, Kwanmien;Jheon, Sanghoon;Lee, Hei-jin;Do, Sang-Hwan
    • Korean Journal of Anesthesiology
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    • v.72 no.2
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    • pp.135-142
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    • 2019
  • Background: Cholesterol plays an important role in the action of opioid analgesics, but its association with postoperative pain has not been clarified. Our study examined the association of pre- and postoperative total serum cholesterol (TSC), and change between the pre- and postoperative TSC levels with postoperative pain outcomes in patients with non-small cell lung cancer (NSCLC) who underwent video-assisted thoracoscopic surgery (VATS) lobectomy. Methods: We retrospectively reviewed medical records of patients with NSCLC who underwent VATS lobectomy at the Seoul National University Bundang Hospital in South Korea. We sought to determine the association between preoperative TSC, TSC on postoperative day (POD) 0-1, and pre- and postoperative changes in TSC by comparing numeric rating scale (NRS) scores on POD 0, 1, and 2 and total morphine equivalent consumption on POD 0-2. Multivariate linear regression analyses were used, and P < 0.05 was considered statistically significant. Results: A total of 1,720 patients with NSCLC who underwent VATS lobectomy were included in the analysis. The change in TSC, preoperative TSC, and postoperative TSC showed no associations with morphine equivalent consumption on POD 0-2 (P > 0.05). In addition, the changes in TSC, preoperative TSC, and postoperative TSC were not associated with postoperative NRS pain score on POD 0, 1, and 2 (P > 0.05). Conclusions: Our results indicated that no significant association was observed between pre- and postoperative TSC level and postoperative pain outcome after VATS lobectomy of the lung.

Analysis of Electrochemical Corrosion Resistance of Inconel 625 Thermal Spray Coated Fin Tube of Economizer (Inconel 625 용사코팅된 절탄기 핀튜브의 전기화학적 내식성 분석)

  • Park, Il-Cho;Han, Min-Su
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.27 no.1
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    • pp.187-192
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    • 2021
  • In this study, Inconel 625 was used as a thermal spray material to prevent dew point corrosion damage to the economizer tube, and sealing treatment was performed after applying the arc thermal spray coating technology. Various electrochemical experiments were conducted in the 0.5 wt% sulfuric acid solution to analyze the corrosion resistance of the thermal spray coating (TSC) layer. After the anodic polarization experiment, the degree of corrosion damage was determined through a scanning electron microscope and EDS component analysis. When measuring the open circuit potential, the effect of the sealing treatment was confirmed through stable potential formation of the TSC+sealing treatment (TSC+Sealing). As a result of the anodic polarization experiment, the passivation region was confirmed in TSC and TSC+Sealing, and corrosion resistance was improved as no corrosion damage was observed. In addition, the corrosion resistance of TSC+Sealing was the best when analyzing the corrosion potential and corrosion current density calculated by Tafel analysis.

Thermally Stimulated Current Analysis of (Ba, Sr)TiO$_3$ Capacitor ((Ba, Sr)TiO$_3$ 커패시터의 Thermally Stimulated Current분석)

  • Kim, Yong-Ju;Cha, Seon-Yong;Lee, Hui-Cheol;Lee, Gi-Seon;Seo, Gwang-Seok
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.38 no.5
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    • pp.329-337
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    • 2001
  • It has been known that the leakage current in the low field region consists of the dielectric relaxation current and intrinsic leakage current, which cause the charge loss in dynamic random access memory (DRAM) storage capacitor using (Ba,Sr)TiO$_{3}$ (BST) thin film. Especially, the dielectric relaxation current should be seriously considered since its magnitude is much larger than that of the intrinsic leakage current in giga-bit DRAM operation voltage (~IY). In this study, thermally stimulated current (TSC) measurement was at first applied to investigate the activation energy of traps and relative evaluation of the density of traps according to process change. And, through comparing TSC to early methods of I-V or I-t measurement and analyzing, we identify the origin of the dielectric relaxation current and investigate the reliability of TSC measurement. First, the polarization condition such as electric field, time, temperature and heating rate was investigated for reliable TSC measurement. From the TSC measurement, the energy level of traps in the BST thin film has been investigated and evaluated to be 0.20($\pm$0.01) eV and 0.45($\pm$0.02) eV. Based on the TSC measurement results before and after rapid thermal annealing (RTA) process, oxygen vacancy is concluded to be the origin of the traps. TSC characteristics with thermal annealing in the MIM BST capacitor have shown the same trends with the current-voltage (I-V) and current-time (I-t) characteristics. This means that the TSC measurement is one of the effective methods to characterize the traps in the BST thin film.

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TV표준방식 변환장치

  • 이권호
    • The Magazine of the IEIE
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    • v.3 no.2
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    • pp.36-45
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    • 1976
  • 오늘날 실시되고 있는 각국의 칼라/흑백 TV 방송의 표준은 잡다한 것 같으나 간추리면 525/60625/50의 2개방식을 NTSC, PAL 및 SECAM의 칼라 3방식으로 채택하고 있다. 한편 통신위성에 의하여 TV방송프로는 국제간에 하시하처에서나 즉시중계가 가능해야하기 때문에 또 앞으로는 방송위성이 등장하게 됨으로 이 표준방식변환(TSC)장치가 꼭 필요하고 매우 중요하게 되었다. 본고에서는 일본 NHK방송센터에 설치된 인터레이스내주사선내압방식 디지털 TSC를 중심으로 TSC의 발달, 표준변환의 원리, 또 여기쓰이는 기억소자로서의 메모리 유형 및 최신의 TSC연구방향으로서 프레임 내주사선내압방식디지털 TSC등을 간약하게 해설하고져 한다.

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Study on the Fire Resistance Performance of the TSC Beam (TSC 합성보의 내화성능에 관한 연구)

  • Kim, Sung Bae;Choi, Seng Kwan;Lee, Chang Nam;Kim, Sang Sup
    • Journal of Korean Society of Steel Construction
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    • v.18 no.1
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    • pp.113-122
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    • 2006
  • The purpose of this paper is to evaluate the fire resistance of the TSC beam, a composite beam composed of a concrete beam enclosed by steel plates. Since a discrepancy was observed between the structural mechanisms of TSC and typical composite beams, the fire performances of the two beams are likewise believed to be partially dissimilar. In this experiment, small and medium-sized TSC beams were tested under given conditions in the laboratory, with/without one of the most widely used spray-on fire protections in Korea. Furthermore, based on the steel and concrete properties under elevated temperatures that were obtained from Eurocode, temperature development across the section was suggested, analyses. To determine the capacity of a modified plastic section, th e fire performance of the model was also examined.

Fuzzy inference systems based prediction of engineering properties of two-stage concrete

  • Najjar, Manal F.;Nehdi, Moncef L.;Azabi, Tareq M.;Soliman, Ahmed M.
    • Computers and Concrete
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    • v.19 no.2
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    • pp.133-142
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    • 2017
  • Two-stage concrete (TSC), also known as pre-placed aggregate concrete, is characterized by its unique placement technique, whereby the coarse aggregate is first placed in the formwork, then injected with a special grout. Despite its superior sustainability and technical features, TSC has remained a basic concrete technology without much use of modern chemical admixtures, new binders, fiber reinforcement or other emerging additions. In the present study, an experimental database for TSC was built. Different types of cementitious binders (single, binary, and ternary) comprising ordinary portland cement, fly ash, silica fume, and metakaolin were used to produce the various TSC mixtures. Different dosages of steel fibres having different lengths were also incorporated to enhance the mechanical properties of TSC. The database thus created was used to develop fuzzy logic models as predictive tools for the grout flowability and mechanical properties of TSC mixtures. The performance of the developed models was evaluated using statistical parameters and error analyses. The results indicate that the fuzzy logic models thus developed can be powerful tools for predicting the TSC grout flowability and mechanical properties and a useful aid for the design of TSC mixtures.

Effects of Brewery Meal-Based Fermented Feedstuff Supplemented with Aspergillus Oryzae or Saccharomyces Cerevisiae on Ruminal Microorganism (Aspergilus Oyzae 혹은 Saccharomyces Cerevisiae를 첨가하여 제조한 맥주박 위주 발효사료가 반추위 미생물에 미치는 영향)

  • Park, Byung-Ki;Ra, Chang-Six;Kim, Byong-Wan;Oh, Jin-Seok;Shin, Jong-Suh
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.25 no.4
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    • pp.307-318
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    • 2005
  • This study was conducted to examine effects of brewery meal-based fermented feedstuff supplemented with Aspergillus oryzae(AO) or Saccharomyces cerevisiae(SC) on luminal micro-organism of Korean native cattle. Two cows equipped with luminal cannulas were used as experimental animals. Experiment was done with three treatment groups: $71.5\%$ of commercial feed and $28.5\%$ of com silage(control): $45.0\%$ of commercial feed, $26.5\%$ of fermented feedstuff supplemented with AO and $28.5\%$ of corn silage(TAO): $45.0\%$ of commercial feed, $26.5\%$ of fermented ffedstuff supplemented with SC and $28.5\%$ of corn silage(TSC). The number of total viable bacteria (p<0.05), anaerobic fungi and protozoa(p<0.05) was higher in TAO and TSC than in control. The number of proteolytic bacteria(p<0.05), cellulolytic bacteria and xylan fermenters tended to be higher in TAO and TSC than in control. The dry matter recovery (DMR) of protozoa was higher in TAO and TSC than in control(p<0.05). The crude protein (CP) content of total microbes and protozoa was higher in TSC than in control and TAO (p<0.05). The CP content of bacteria was higher in TAO and TSC than in control(p<0.05). The ether extract(EE) content of the total microbes was higher in TAO than in control and TSC(p<0.05), and the EE of protozoa and bacteria were higher in TSC than in control and TAO(p<0.05). The ratio of essential amino acids of total microbe was higher in control than in TAO and TSC(p<0.05). The ratio of methionine and alanine of bacteria was higher in TAO and TSC than in control(p<0.05). The results suggested that the feeding of fermented feedstuff supplemented with AO or SC had an influence on the numbers of ruminal microorganism and the changes of microbial body composition.