• Title, Summary, Keyword: TPM

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An Empirical Study of influence Factor to TPM Performance in medium and small enterprises (중소기업 TPM 성과에 영향을 주는 요인에 대한 실증적 연구)

  • Choi, Moo-Ho;Ree, Sang-Bok
    • Journal of the Korean Society for Quality Management
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    • v.38 no.3
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    • pp.449-462
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    • 2010
  • In this Paper, We analyzed influence Factor to TPM Performance in medium and small enterprises by empirically. By Literature survey, We hypothesize education training and 5S influence to individual improvement, independence maintenance, planning and foresight, which also influence to flexibility, total equipment performance, quality, which finally influence to lower cost, delivery date. To analyze empirically, we survey questionnaire in medium and small enterprises being below 300 people. From statistical analysis, 7 hypotheses are rejected, which is different existing research. This is analyzed that reflect actuality that medium and small enterprises is different from large enterprises. We expect that result of this treatise does concentration effort in important factor to get TPM performance in medium and small enterprises.

TPM 활동에서 TOC 활용 방안

  • 강인선
    • Proceedings of the Korean Operations and Management Science Society Conference
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    • pp.633-636
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    • 2003
  • TPM은 생산시스템 효율화를 극한 주구하는 기업 체질 구축을 목표로 하는 경영혁신 활동의 도구로 90년초 부터 국내 기업에 도입, 추진되어 활성화되어 있다 본 연구는 TPM 전개 활동에서 생산효율화 저해 요소의 파악 및 개선을 효율적으로 추진하기 위하여 TOC의 활용하는 방안을 모색해 본다

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Comparison of Acid and Phenol Compounds in Smoke Total Particulate Matter by the Different Tobacco Leaves (잎담배 종류 및 등급에 따른 담배 연기응축물의 Acid 및 Phenol 화합물 함량 비교)

  • 황건중;이문수;나도영;장기철
    • Journal of the Korean Society of Tobacco Science
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    • v.22 no.1
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    • pp.84-90
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    • 2000
  • This study was conducted to determine the acid and phenol compounds in smoke total particulate matter(TPM) by the different tobacco variety, and grade of tobacco leaves. Sixteen kinds of tobacco leaves which were flue-curd, burley, orient, reconstituted tobacco, expanded stem, and expanded cut tobacco, were selected for this study. After collecting a TPM by using smoking machine, the concentration of TPM components was analyzed by GC. Acid components of TPM of mainstream smoke were different from the variety and grade. The order of the highest concentration of acid compounds in TPM was flue-cured > orient> burley> expanded cut tobacco> reconstituted tobacco> expanded stem. Though lactic acid and glycolic acid concentrations in flue-cured tobacco were twice higher than those in burley tobacco, the contents of 2-furoic acid and 3,4-dihydroxy butanoic acid in burley tobacco were higher than those in flue-cured tobacco. The content of phenolic compounds in the high grade and thick leaves was higher than that in other tobacco leaves. Phenol and catechol compounds in burley CD3W-2 revealed the least value in concentration among the samples tested. Pyrocatechol and hydroquinone concentrations in flue-cured tobacco were 2-3 times higher than those in burley and orient tobacco.

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명사컬럼-글로벌 중소기업의 경영이론 "TPM 법칙"

  • 허범도
    • The Monthly Technology and Standards
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    • pp.11-12
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    • 2007
  • "TPM 법칙"은 글로벌 경영환경 속에서 중소기업이 생존해 나가는데 필요한 하나의 프로세스(process)이자 전략(strategy)이고, 정책(policy )이자 동시에 법칙(law)이다.

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The Effect of Topiramate on Hippocampal Neuronal Death and Expression of Glutamate Receptor in Kainate-induced Status Epilepticus Model (Kainate 유발 간질중첩증 모델에서 topiramate가 해마 신경세포사와 glutamate 수용체 발현에 미치는 영향)

  • Park Min-Jeong;Ha Se-Un;Bae Hae-Rahn;Kim Sang-Ho
    • Journal of Life Science
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    • v.15 no.3
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    • pp.505-512
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    • 2005
  • Excitotoxicity and epileptogenesis have often been associated with glutamate receptor activation. Accumulating evidences indicates that topiramate (TPM), an antiepileptic drug with multiple mechanisms of action has neuroprotective activity. We explored the neuroprotective effect of TPM on the status epilepticus (SE)-induced hippocampal neuronal death. After development of SE by kainite injection (15 mg/Kg), rats were treated with TPM (10mg/kg) for 1 week. The neuronal death was detected by Apop tag in situ detection kit, and the expression levels of glutamate receptors were semi-quantitatively analyzed by immunoblot. Kainate-induced SE caused a significant neuronal death and cell loss in CAI and CA3 regions of hippocampus at 1 week. However, treatment of TPM for 1 week after SE markedly reduced hippocampal neuronal death. The expression of N-methyl-D-aspartate (NMDA) receptor subunit 1, was increased by SE, but was not affected by 1 week treatment of TPM. The expressions of NMDA receptor subunit 2a and 2b were not changed by either SE or TPM. As for ${\alpha}-amino-3-hydroxy-5-methyl-4-isoxazole-propionate$ (AMPA) glutamate receptors (GluR), kainate-induced SE markedly up-regulated GluR1 expression but down-regulated GluR2 expression, leading to increased formation of $Ca^{2+}$ permeable GluR2- lacking AMPA receptors. TPM administration for 1 week attenuated SE-induced expression of both the up-regulation of GluR1 and down-regulation of GluR2, reversing the ratio of GluR1/GluR2 to the control value. In conclusion, TPM protects neuronal cell death against glutamate induced excitotoxicity in kainate-induced SE model, supporting the potential of TPM as a neuroprotective agent.

Acoustic Variations in Epileptic Patients with Topiramate (간질 치료제 복용으로 인한 음성학적인 변화에 대한 연구)

  • Choi, Yoon-Mi;Kim, Sun-Jun;Kim, Hyun-Gi
    • Speech Sciences
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    • v.14 no.4
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    • pp.221-232
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    • 2007
  • Topiramate (TPM) is a new antiepileptic drug characterized by a clinical effective reduction in seizure frequency and it represents a useful drug effective in a wide range of epileptic patients. Known side effects are represented by weight loss, hypohidrosis, anorexia, sedation, nephrolithiasis, cognitive complaints and language disorders. This study is to examine acoustic characteristics of patients with TPM. 15 patients were assessed through a Computerized Speech Lab (CSL) applied before the beginning of therapy with TPM and 3 months after medication had been stabilized. Tests had been chosen to assess voice onset time (VOT), total duration (TD), vowel formants, loudness, pitch, speaking rate, and articulation patterns. We compared the data from patients and healthy volunteers. The statistical analysis of the results did not show changes in acoustic tests, except for TD which was increased. The increase of the TD is evaluated as a deterioration of fluency. Our results suggest that patients with TPM did not experience acoustic speech changes except that fluency was declined. Unlike previous studies, the medication of TPM has nothing to do with speech problems in patients with epilepsy.

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Development and Implementation of Chain Metrics for Obtaining Lean Overall Equipment Effectiveness Using Availability Measures (시간가동률 척도에 의한 Lean OEE의 연계지표 개발 및 적용)

  • Choi, Sung-Woon
    • Journal of the Korea Safety Management and Science
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    • v.14 no.2
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    • pp.147-158
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    • 2012
  • This paper aims to develop a new chain metrics for obtaining lean Overall Equipment Effectiveness(OEE) and present implementation strategy which considers the properties for Total Productive Maintenance(TPM) to reduce machine losses, Performance Analysis and Control(PAC) to reduce labor losses, Lean Production System(LPS) to reduce floor wastes, and Theory of Constraints(TOC) to minimize the problem of Capacity Constrained Resource(CCR). The study reviews the related literatures and reformulates the structure of machine losses, labor losses and field wastes. The research also develops the integrated productivity metrics according to time, units, reliability and maintainability. It is found that the study develops the actual productivity measure in terms of efficiency, effectiveness and standard productivity. In addition to that, it outlines and develops by using the integrated LPS and TPM, lean OEE measures such as Time Based Productivity(TBP), Unit Based Productivity(UBP), and Reliability & Maintainability Based Availability(RMBA). Implication examples are proposed to make it easier and available for practioners to understand the implementation strategies about TPM OEE, lean OEE and TOC OEE. Futhermore related to other studies, the research contributes to create a new chain productivity measures to clear the interrelationship concepts of productivity, efficiency and effectiveness. Moreover the paper develops the enhanced OEE measures by integration of TPM, PAC, LPS and TOC with the perspective of schedule, throughput, reliability, maintainability and availability.

Development of line-scanning two-photon microscopy based on spatial and temporal focusing for tryptophan based auto fluorescence imaging (고속 트립토판 자가형광 이미징을 위한 시공간적 집중 기반의 라인 스캐닝 이광자 현미경 개발)

  • Lee, Jun Ho;Nam, Hyo Seok;Kim, Ki Hean
    • Journal of the Korean Society of Visualization
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    • v.11 no.2
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    • pp.41-45
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    • 2013
  • Two-photon microscopy (TPM) is minimally-invasive 3D fluorescence microscopy based on nonlinear excitation, and TPM can visualize cellular structures based on auto-fluorescence. Line-scanning TPM is one of high-speed TPM methods without sacrificing the image resolution by using spatial and temporal focusing. In this paper, we developed line-scanning TPM based on spatial and temporal focusing for auto-fluorescence imaging by exciting the tryptophan. Laser source for this system was an optical parametric oscillator (OPO) and it made near 570 nm femtosecond pulse laser. It had 200fs pulse width and 1.72 nm bandwidth, so that the achievable depth resolution was 2.41um and field of view (FOV) is 10.8um. From the characterization, our system has 3.0 um depth resolution and 12.3 um FOV. We visualized fixed leukocyte cell sample and compared with point scanning system.

종합생산성모델(TPM)을 사용한 생산성 측정

  • 박광태;김민철
    • Proceedings of the Korean Operations and Management Science Society Conference
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    • pp.197-200
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    • 1997
  • Each company is more interested in the productivity to achieve cost reduction and profit maximization through productivity improvement. With this trend, we show the method to measure productivity using TPM(Total Productivity Model) which considers all the input factors of the company instead of using partial productivity such as labor and/or capital productivity We also examine the relation of productivity versus output, profit versus output and profit versus productivity of the case company by actually applying the TPM and suggest the optimal level of profit and output for this company.

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Studies on the Phenol Compounds in Smoke Total Particulate Matters of Flue-cured Tobacco Leaves (황색종 잎담배의 연기응축물중 페놀 화합물에 관한 연구)

  • 복진영;백순옥;김상범;안동명;조수헌
    • Journal of the Korean Society of Tobacco Science
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    • v.23 no.2
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    • pp.162-167
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    • 2001
  • This study was carried out to quantitatively determine phenol compounds in smoke total particulate matter(TPM) to evaluate the qualititive characteristics of flue-cured tobacco varieties(NC82, KFl14 and KFl18). After collecting The TPM by using smoking machine, the concentration of phenol compounds were analyzed by gas chromatography as their trimethylsilyl derivative on a fused capillary column bonded with a 5% PE ME siloxane stationary phase. In all the flue-cured tobacco varieties, the major phenol components were monohydroxy compounds. The order of the highest concentration of total phenol compounds in TPM was NC82, KF114 and KFl18 but the contents of dihydroxy compound in the KFl18 was higher than those of NC82 and KF114.

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