• Title, Summary, Keyword: Synthesis

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Optimum MVF Estimation-Based Two-Band Excitation for HMM-Based Speech Synthesis

  • Han, Seung-Ho;Jeong, Sang-Bae;Hahn, Min-Soo
    • ETRI Journal
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    • v.31 no.4
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    • pp.457-459
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    • 2009
  • The optimum maximum voiced frequency (MVF) estimation-based two-band excitation for hidden Markov model-based speech synthesis is presented. An analysis-by-synthesis scheme is adopted for the MVF estimation which leads to the minimum spectral distortion of synthesized speech. Experimental results show that the proposed method significantly improves synthetic speech quality.

Recovery of RNA Synthesis After Ultraviolet Irradiation of Xeroderma Pigmentosum Group F and G (색소성 건피증 세포 F, G군의 자외선 조사 후 RNA 합성 회복에 관한 연구)

  • 장해룡
    • Toxicological Research
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    • v.15 no.1
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    • pp.35-38
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    • 1999
  • RNA synthesis rate was measured at different time points after UV irradiation in various xeroderma pigmentosum (XP) cells including complementation groups F and G. The RNA synthesis was assayed by measuring 3H-uridine incorporation. In normal cells, recovery of RNA synthesis was initiated at about 6 hr ager UV irradiation and reached to the same level as in unirradiated cells at 24hr after UV irradiation. By contrast, no such recovery was observed in group F,G XP cells.

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Concise Synthesis of Flurbiprofen via Palladium-Catalyzed Cross-Coupling Reactions (팔라듐 촉매하 결합반응을 이용한 플루비프로펜의 간결한 합성)

  • Han, Young Taek
    • YAKHAK HOEJI
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    • v.59 no.2
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    • pp.66-69
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    • 2015
  • A concise synthesis of flurbiprofen, a member of the non-steroidal anti-inflammatory 2-arylpropionic acids, has been accomplished. The key feature of this synthesis involves successive palladium-catalyzed cross coupling reactions. In particular, a 2-arylacylate intermediate, which easily converted to the key 2-arylpropionic acid scaffold, was afforded by a versatile palladium-catalyzed cross coupling reaction between diazopropanate and bisphenylboronic acid. This synthetic procedure would facilitate synthesis of the flurbiprofen and anti-inflammatory 2-arylpropionic acid derivatives.

Efficient Synthesis of An Epoxy Alcohol, A key Intermediate for$LTA_4$ Synthesis

  • Hokoon Park;Yong Sup Lee;Sang Chul Shim
    • Bulletin of the Korean Chemical Society
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    • v.13 no.5
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    • pp.551-553
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    • 1992
  • An efficient and very short synthesis of epoxy alcohol 5, a key intermediate for leukotriene synthesis, was described. The key reaction involves the regioselective benzylidene acetal formation from methyl 5,6,7-trihydroxyheptanoate 1.

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Synthesis of Melandrin (Melandrin의 합성)

  • 문정술;이강노;임중기;우원식
    • YAKHAK HOEJI
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    • v.35 no.4
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    • pp.332-334
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    • 1991
  • The synthesis of melandrin has been accomplished in good yield by the reaction of 5-tosyloxyanthranilic acid ethyl ester with p-acetoxybenzoyl chloride, followed by removal of protecting groups with methanolic ammonia.

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