• Title, Summary, Keyword: Stomach neoplasms

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A Study on the Retrieval Effectiveness of KoreaMed using MeSH Search Filter and Word-Proximity Search (검색용 MeSH 필터와 단어인접탐색 기법을 활용한 KoreaMed 검색 효율성 향상 연구)

  • Jeong, So-Na;Jeong, Ji-Na
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.18 no.5
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    • pp.596-607
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    • 2017
  • This study examined the method for adding related to "stomach neoplasms" as filters to the Medical Subject Headings (MeSH) for search as well as a method for improving the search efficiency through a word-proximity search by measuring the distance of co-occurring terms. A total of 8,625 articles published between 2007 and 2016 with the major topic terms "stomach neoplasms" were downloaded from PubMed article titles. The vocabulary to be added to the MeSH for search were analyzed. The search efficiency was verified by 277 articles that had "Stomach Neoplasms" indexed as MEDLINE MeSH in KoreaMed. As a result, 973 terms were selected as the candidate vocabulary. "Gastric Cancer" (2,780 appearances) was the most frequent term and 7,376 compound words (88.51%) combined the histological terms of "stomach" and "neoplasm", such as "gastric adenocarcinoma" and "gastric MALT lymphoma". A total of 5,234 compounds words (70.95%), in which the co-occurring distance was two words, were found. The matching rate through the MEDLINE MeSH and KoreaMed MeSH Indexer was 209 articles (75.5%). The search efficiency improved to 263 articles (94.9%) when the search filters were added, and to 268 articles (96.7%) when the 13 word-proximity search technique of the co-occurring terms was applied. This study showed that the use of a thesaurus as a means of improving the search efficiency in a natural language search could maintain the advantages of controlled vocabulary. The search accuracy can be improved using the word-proximity search instead of a Boolean search.

Photodynamic Therapy for Neoplasms in Intrathoracic Constructed Stomach (식도암 수술 후 흉곽 내 위장에 발생한 원발성 위암에 대한 광역동치료 -1예 보고 -)

  • Park, Ki-Sung;Ko, Moo-Sung;Kwon, Oh-Choon;Lee, Sub;Kim, Jong-Ki;Jheon, Sang-Hoon
    • The Korean Journal of Thoracic and Cardiovascular Surgery
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    • v.36 no.10
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    • pp.794-797
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    • 2003
  • Photodynamic therapy (PDT) is a local, endoscopically controlled nonoperative therapeutic technique based on selective sensitization of mucosal, malignant and precancerous lesions of the esophagus, trachea and bronchus prior to light-induced tissue destruction in the department of thoracic and cardiovascular surgery. PDT is effective and safe for palliative treatment of neoplasms in the stomach, esophagus, and lung. But skin phototoxicity is unsatisfactory, therefore optimization of management of post-PDT is necessary for preventing phototoxic side effects of skin. Careful patient education in photoprotection techniques, close patient follow-up, early dermatologic referral and medical treatment are recommended. We performed PDT in a patient with intrathoracic constructed stomach. We report this case with a brief review of literatures, therefore.

Synchronous Multiple Primary Cancers of the Esophagus, Stomach, Lung and Oral Cavity (식도, 위, 폐 그리고 구강에 동시 발생한 다발성 원발암)

  • Shin, Su-Min;Shim, Young-Mog
    • The Korean Journal of Thoracic and Cardiovascular Surgery
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    • v.42 no.5
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    • pp.662-665
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    • 2009
  • A 65-year-old-male had a mass in the oral cavity, and this was ultimately determined to be squamous cell carcinoma and he underwent wide excision for it. Postoperatively, he underwent the staging work up; this showed that he had other cancers in the esophagus, stomach and lung. We performed a curative resection of all the lesions simultaneously. We report here on a case of synchronous multiple cancers of the esophagus, stomach, lung and oral cavity.

Excision of Malignant Gastrointestinal Stromal Tumor of Distal Esophagus and Stomach using Thoracoabdominal Incision (흉복부 절개를 이용한 식도와 위에 발생한 거대 악성 위장관 간질 종양의 절제)

  • Hwang Jin Wook;Son Ho Sung;Jo Jong Ho;Park Sung Min;Lee Song Am;Sun Kyung;Kim Kwang Taik
    • The Korean Journal of Thoracic and Cardiovascular Surgery
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    • v.38 no.7
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    • pp.514-517
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    • 2005
  • Gastrointestinal stromal tumor is documented on every part of the gastrointestinal tract. It develops in the stomach and the small intestine most commonly, and also in the esophagus. A 44 year-old male patient was admitted due to dysphagia and weight loss. Chest CT showed about $15\times11\times11cm$ sized, well-defined, and lobulated soft tissue mass with central necrosis was noted in the posterior wall of lower esophagus throughout the lesser curvature of upper stomach. We performed the distal esophagectomy and total gastrectomy using thoracoabdominal incision. The tumor was positive at CD117 (c-kit) and CD 34, and was diagnosed as malignant GIST of the distal esophagus and upper stomach. The patient is on routine follow up at the out patient department for nineteen months up to now.

Gastric Cancer and Angiogenesis: Is VEGF a Useful Biomarker to Assess Progression and Remission?

  • Macedo, Filipa;Ladeira, Katia;Longatto-Filho, Adhemar;Martins, Sandra F.
    • Journal of Gastric Cancer
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    • v.17 no.1
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    • pp.1-10
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    • 2017
  • Gastric cancer (GC) has high mortality owing to its aggressive nature. Tumor angiogenesis plays an essential role in the growth, invasion, and metastatic spread of GC. The aim of this work was to review the angiogenic biomarkers related to the behavior of GC, documented in the literature. A search of the PubMed database was conducted with the MeSH terms: "Stomach neoplasms/blood [MeSH] or stomach neoplasms/blood supply [MeSH] and angiogenic proteins/blood [Major]". A total of 30 articles were initially collected, and 4 were subsequently excluded. Among the 26 articles collected, 16 examined the role of vascular endothelial growth factor (VEGF), 4 studied endostatin, 3 investigated angiopoietin (Ang)-2, 2 studied the Ang-like protein 2 (ANGTPL2), and 1 each examined interleukin (IL)-12, IL-8, and hypoxia inducible factor. Regarding VEGF, 6 articles concluded that the protein was related to lymph node metastasis or distant metastases. Five articles concluded that VEGF levels were elevated in the presence of GC and decreased following tumor regression, suggesting that VEGF levels could be a predictor of recurrence. Four articles concluded that high VEGF levels were correlated with poor prognosis and lower survival rates. Ang-2 and ANGTPL2 were elevated in GC and associated with more aggressive disease. Endostatin was associated with intestinal GC. VEGF is the most extensively studied angiogenic factor. It is associated with the presence of neoplastic disease and lymph node metastasis. It appears to be a good biomarker for disease progression and remission, but not for diagnosis. The data regarding other biomarkers are inconclusive.

Influencing Factors on Depression in Stomach Cancer Patients Receiving Chemotherapy (항암화학요법을 받는 위암 환자의 우울과 영향요인)

  • Kim, Jeong Hye
    • Korean Journal of Adult Nursing
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    • v.24 no.6
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    • pp.588-596
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    • 2012
  • Purpose: The purpose of this study was to identify factors that influence depression in stomach cancer patients receiving chemotherapy at outpatient clinic. Methods: A cross-sectional design was used. Ninety two subjects diagnosed with stomach cancer and receiving chemotherapy agreed to participated in the study. Subjects completed a survey which included questions about depression, symptom experience, social support and self-efficacy. Results: The level of depression was $13.45{\pm}6.92$. Reported depression differed according to patient's perceived health status. Depression was significantly correlated with symptom experience, social support and self-efficacy. The most important factor related to depression was symptom experience, followed by social support and self-efficacy. These three factors could explain about 47% of depression in stomach cancer patients receiving chemotherapy. Conclusion: Although the level of depression in stomach cancer patients receiving chemotherapy was relatively low, 34.8% of patients reported to have depression. It is important to apply nursing intervention including screening of depression level in stomach cancer patients receiving chemotherapy that focused on symptom experience and to consider about social support and self-efficacy at outpatient clinic.

Distress, Depression, Anxiety, and Spiritual Needs of Patients with Stomach Cancer (위암 환자의 고통, 불안, 우울 및 영적 요구)

  • Wi, Eun Sook;Yong, Jinsun
    • Asian Oncology Nursing
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    • v.12 no.4
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    • pp.314-322
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    • 2012
  • Purpose: This study was to investigate relationships among distress, depression, anxiety, and spiritual needs of hospitalized patients with stomach cancer. Methods: The participants were 120 in-patients with stomach cancer for surgery or chemotherapy at C University in Seoul from December 2010 to February 2011. To measure emotional and spiritual states was used Distress management version 1 (National Comprehensive Cancer Network, NCCN), the Hospital anxiety and Depression Scale (HADS), and the Spiritual Needs Scale. The data were analyzed using SPSS 19.0, specifically descriptive statistics, t-test, ANOVA, Scheffe's test, and Pearson's correlation coefficients. Results: Distress showed positive correlations with anxiety (r=.49, p<.001), and depression (r=.44, p<.001). Anxiety showed positive correlations with depression (r=.59, p<.001). While, depression showed negative correlations with spiritual needs (r=-.25, p<.001). Conclusion: This study's findings show that hospitalized patients with stomach cancer experienced distress, anxiety, depression and high spiritual needs. Distress, anxiety, and depression of patients with stomach cancer were positively correlated with each other. While the level of depression was negatively correlated with the level of spiritual needs, indicating the higher the level of depression, the lower the spiritual needs. Therefore, nursing interventions for emotional and spiritual support need to be developed for stomach cancer patients.

Incidence and Significance of Multiple Primary Malignant Neoplasms (다발성 원발성 악성 종양 - 121 예의 임상적 분석-)

  • Choi Eun Kyung;Cho Moon June;Ha Sung Whan;Park Charn Il;Bang Young Ju;Kim Noe Kyung
    • Radiation Oncology Journal
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    • v.4 no.2
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    • pp.129-133
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    • 1986
  • To know the three questions about multiple primary cancers: 1) what are the characteristics of persons having multiple parimary cancer? 2) Does the presence of a single primary concer after the susceptability to multiple primary cancers? 3) Does the location of one multiple primary cancer influence the site of others?, we analysed 121 cases of multiple primary malignant neoplasms registered in Seoul National University Hospital during 8 years from July 1978 to August 1986. Of 121 cases, double primary malignant neoplasms were 119 cases and triples were 2 cases. The incidence of multiple primary malignant neoplasms was $0.7\%$. The metachronous tumor (>6 months) was found in 70 cases and the median time between the first and the second was 32 months. The most commonly associated tumors were stomach and primary liver carcinoma. Cervix and Lung cancer, Stomach and Rectal cancer, Stomach and Esophagus cancer were also commonly associated.

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Cytologic Analysis of Metastatic Malignant Tumor in Pleural and Ascitic Fluid (흉수 및 복수로 전이된 암종의 세포학적 분석)

  • Joo, Mee;Cho, Hye-Je
    • The Korean Journal of Cytopathology
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    • v.6 no.2
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    • pp.125-132
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    • 1995
  • Cytodiagnosis of pleural and ascitic fluid is a commonly performed laboratory examination. Especially, positivity for malignant cells in effusion cytology is very effective and also presents the first sign of malignancy in unknown primary site of the tumor. We examined each 34 cases of pleural and ascitic fluid cytologic specimen diagnosed as metastatic tumor, which was selected among 964 pleural fluid cytology cases and 662 ascitic fluid cytology cases from September 1989 to June 1995. Among the pleural fluid cytology specimens examined, 34 specimens were positive in 27 patients. The lung was the most frequent primary site(44%), followed by the stomach (12%), lymphoreticular neoplasm(12%), pancreas(3%) and colon(3%). And the cases of unknown primary site with positive pleural biopsy alone were 24%. Among trio ascitic fluid cytology specimens examined, 34 specimens were positive in 29 patients. The most common primary neoplasms. were carcinomas of ovary(32%), stomach(22%), colon(6%), breast(3%), pancreas(3%), and lung(3%) and lymphoreticular neoplasms(3%) The metastatic tumor was predominantly adenocarcinoma type in both pleural(82%) and ascitic(91%) fluid. The study of metastatic adeno- carcinoma in effusion from lung, ovary, and stomach was undertaken to find distinctive features for the identification of the primary site. The smears of metastatic pulmonary adenocarcinoma had a tendency to show high grade pleomorphism and many large tight cell clusters, whereas that of the ovarian adenocarcinoma showed low grade pleomorphism with abundant intracytoplasmic vacuoles in relatively clear background. That of the stomach revealed the intermediate features.

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Fatigue and Related Factors in Patients with Stomach Cancer during Chemotherapy (항암화학요법을 받는 위암 환자의 피로 변화 양상과 관련요인)

  • Kim, Sun-Hee
    • Asian Oncology Nursing
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    • v.10 no.1
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    • pp.10-18
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    • 2010
  • Purpose: This study was intended to identify the patterns of fatigue and its related factors in patients with stomach cancer during chemotherapy. Methods: Thirty participants (24 males and 6 females) were recruited for this study which utilized a longitudinal and descriptive approach. The research instruments included the Revised Piper Fatigue Scale, Symptom Distress Scale, and Linear Analogue Self Assessment Scale. The participants received 5-FU and Adriamycin at the first week and 5-FU only at the second and third week. The instruments were measured six times in total. The data were analyzed using SPSS 17.0. Results: It was found that fatigue scores in patients with stomach cancer, receiving 5-FU and Adriamycin (FA) regimen, reached the highest level on the third day (F=9.37, p=.024) after the initial infusion, and decreased gradually afterward. The symptom and psychological distress scores illustrated very similar pattern. The concept of multidimensionality of fatigue in patients with stomach cancer was supported in this study, showing that all four dimensions of the scale were positively correlated. Conclusion: The results of this study provided useful information of patients with stomach cancer on fatigue and other related symptoms which they experienced during weekly scheduled chemotherapy with FA regimen.