• Title, Summary, Keyword: Small Intestine

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Clostridium perfringens Type A Infection in a Hippopotamus amphibius Cub (새끼 하마에서 Clostridium perfringens Type A 감염 증례)

  • Kim, Young-Seob;Lim, Suk-Kyung;Shin, Nam-Shik
    • Journal of Veterinary Clinics
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    • v.25 no.4
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    • pp.310-313
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    • 2008
  • C. perfringens is the most important enteric clostridial pathogen of animals. C. perfringens type A has been associated with hemorrhagic enteritis in a wide lange of domestic and wild mammals. But all types of C. perfringens can be normal inhabitants of the intestine of most mammals. We have a special case that showed C. perfringens type A infection in a hippopotamus (Hippopotamus amphibius) cub at Seoul Grand Park Zoo. Male, hippopotamus cub died in 3 days after birth. Clinical features of the hippopotamus cub have showed lethargy and anorexia before death. Gross post-mortem findings of the hippopotamus were hemorrhagic enteritis of intestine. Histopathologically, ruminant stomach and intestine showed hemorrhagic lesions and the lumen of the small intestine was filled with mucoid and hemorrhagic fluid. Also, intestine and stomach of hippopotamus were distended with gas and hemorrhagic fluid. C. perfringens was isolated in culture of small intestine and the presence of C. perfringens type A was confirmed by PCR. This case indicated that C. perfringens type A could be considered as a virulence factor responsible for causing death of a newborn hippopotamus.

Tribological Characteristics of Endoscope Capsule Inside of Small Intestine (캡슐형 내시경 개발을 위한 소장 내에서의 캡슐저항력 특성)

  • 백남국;김대은
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • pp.142-145
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    • 2002
  • In order to develop a self-propelled microendoscope, the frictional resistance of the capsule-type endoscope inside the intestine should be understood. In this work the frictional resistance behaviors of capsules with different designs were experimentally investigated using a pig intestine. It was found that cylindrical capsule design had the least frictional resistance. Also, the resistance increased as the speed of the capsule motion was decreased. It is expected that the results of this work will be used to design the optimum propulsion system for the microendoscope.

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Small Intestine Resection and Anastomosis for Epiploic Foramen Entrapment of a Horse (말의 그물막구멍포착 교정을 위한 소장 절제 및 문합 1례)

  • Hwang, Hye-shin;Park, Chull-gyu;Hwang, Jun-seok;Chun, Yong-woo;Han, Janet H.;Lee, Inhyung
    • Journal of Veterinary Clinics
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    • v.32 no.4
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    • pp.374-379
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    • 2015
  • A 10-year-old gelding Warmblood weighing 560 kg was referred to J&C Equine Hospital with the history of hyperpnea, depression, pawing, and rolling for 7 hours. According to the results of clinical and ultrasound examination, it was considered that intestines were distended with thickened wall. The horse had been treated with lactated Ringers' solution (14 L, IV), flunixin meglumine (1.1 mg/kg, IV), and mineral oil (1 L, PO), but he did not show any responses to those treatments. Exploratory laparotomy was performed and identified incarcerated small intestine through the epiploic foramen. The horse received resection and anastomosis of the entrapped small intestine. After surgery, the horse was treated with intensive postoperative care of fluid therapy (5 L with 20 mEq/L KCl, every 2 hours), flunixin meglumine (1.1 mg/kg, IV, sid), antibiotics (penicillin 22,000 IU/kg, IV, qid and gentamicin 6.6 mg/kg, IV, sid), lidocaine constant rate infusion (bolus 1.3 mg/kg over 15 minutes then 0.05 mg/kg/minute), common nutritional supplements, nasogastric intubation every 2 hours and trunk bandage. Postoperative feeding program had started with small amount of hay every 4 hours and gradually increased to normal amount till 5 days. At 77 days after surgery, he showed sudden outbreak of colic and was euthanized. The causes of colic were small intestinal strangulation by passing through the mesenteric rents and postoperative adhesion between small intestines. According to the results, it is recommended to perform perioperative intensive care of horse with colic and to use several methods to prevent adhesions during abdominal surgery of horses.

Effects of Nutritional Level on Digestive Enzyme Activities in the Pancreas and Small Intestine of Calves Slaughtered at Same Body Weight

  • Wang, X.B.;Ogawa, T.;Suda, S.;Taniguchi, K.;Uike, H.;Kumagai, H.;Mitani, K.
    • Asian-Australasian Journal of Animal Sciences
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    • v.11 no.4
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    • pp.375-380
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    • 1998
  • Six Holstein heifer calves weaned at 45 days-of-age were randomly allocated into high daily gain (1.1 kg/d, HDG) and low daily gain (0.56 kg/d, LDG) groups, and were slaughtered at 170 kg of live weight. Energy intake level in the feeding period was 2.4 $\times$ maintenance in 105 days for HDG and 1.4 $\times$ maintenance in 216 days for LDG calves. Total length of the small intestine was identical between groups, but both weights of the pancreas and of the small intestinal mucosa were greater (p < 0.01) for HDG calves. Alpha-amylase, lipase, proteinase, and trypsin activities of the whole pancreas were higher (p < 0.05) in HDG calves. Disaccharidase activity of the whole small intestinal mucosa was also higher (p < 0.10) for HDG than for LDG calves. However, the enzymatic activities, expressed as per gram or per protein of the pancreas and the small intestinal mucosa, were not affected (p > 0.10) by the plane of nutrition. These results suggest that the digestive enzyme activity in the small intestine varies primarily with the weight of tissues synthesizing the enzyme.

IN VIVO INVESTIGATION ON THE INTESTINAL ABSORPTION OF VITAMIN A-ALCOHOL (RETINOL) IN RATS

  • Whang, Eun-Mi;Burger, Hans-Jurgen
    • Proceedings of the Korean Nutrition Society Conference
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    • pp.21-21
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    • 1995
  • Absorption of fat-soluble vi tamin, retinol occurs mainly in the proximal part of small intestine. But its intestinal transport mechanism isn't yet clear. The aim of the present study was to investigate on the mechanism of absorption of retinol by determining a concentration-dependent kinetic of retinol absorption in rats. The study was carried out by applying in vivo technique in which vitamin solution was infused to intestinal lumen and at the same time thoracic duct and choledochus duct were canulated to collect samples. The investigations showed that retinol is absorbed in the small intestine by a saturable, carrier-mediated transport system, i.e. wi thout signi ficant differences between the proximal and distal halves of the small intestine. The transport of retinol taken up by the enterocytes occured via different mechanisms: while the main vitamin A transport via the thoracic duct was saturated by limiting transport factors such as retinol-CRBP-II-complex formation and retinol esterification with increasing substrate concentrations, the transport of retinol metabolite product via the portal vein was proportional to the substrate concentration.ration.

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?Effects of Insamyangwee-Tang on Functions of Stomach and Small Intestine in Experimental Animals (인삼양위탕(人蔘養胃湯)이 위장관(胃腸管)에 미치는 영향(影響))

  • Lee Dong-Hyun;Kim Deog-Gon;Jeong Gyu-Mann
    • The Journal of Pediatrics of Korean Medicine
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    • v.1 no.1
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    • pp.23-37
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    • 1986
  • Although the Insamyangwee-Tang has been widely used in clinical purposes in the oriental medicine and its clinical efficiency is documented for the cases of gastritis, gastric ulcer and enteritis but the experimental study on these has not been undertaken. So,To investigate the clinical efficiency, of Insamyangwee-Tang and validate its oriental medical theory, these experiments were undertaken, by being compared with animal experiment. ?The following results were obtained. ?1. By effect of Insamyangwee-Tang on isolated ileum from mice, rats, rabbits and Guinea pigs, the motility of ileums was inhibited remarkably. ?2. By effect of Insamyangwee-Tang on motility of the small intestine in rabbits, the motility was inhibited remarkably too. ?3. Insamyangwee-Tang inhibited charcoal transport functions in the small intestine of mice. ?4. By effect of Insamyangwee-Tang on isolated duodenum from rats, the motility of duodenum was inhibited remarkably.?5. Gastric juice and pepsin secretion was decreased, anti-ulceration effect was recognized.

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The Activity of Xanthine Oxidase (Type O) in Some Partial Portions of Rat Skin

  • Lee, Sang-Hee;Yoon, Chong-Guk
    • Biomedical Science Letters
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    • v.8 no.3
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    • pp.155-159
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    • 2002
  • To evaluate the physiological significance of xanthine oxidase (XO) in rat skin, the activity of XO (type O) in skin was compared with that of small intestine or liver. Concomitantly, XO activities in some partial portions (scalp, leg, dorsal and ventral part) of skin were determined and then compared with each partial portion. XO activity of skin was lower than that of small intestine and rather higher than that of liver. Furthermore, the activity of XO in skin, after clipping of hairs and then in 5 days, was more increased than that of rat which was clipped before having been sacrificed. As for activities of free radical scavenging system (GPx, GST, SOD), skin is lower than liver and small intestine. Although it is hewn that the oxygen free radical generated by XO system lead to injurious effect on the cell, the XO activity of ventral part which is to be less exposed to xenobiotics and biological agents was the lowest among those of ventral, dorsal, leg and scalp parts in skin. In conclusion, it may be hypothesized that XO system in skin act on defence mechanism.

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Studies on the absorption of mixed compounds of aminopyrine antihistamic agent (Aminopyrine 항히스타민 제혼합물의 흡수에 관한 연구)

  • 한세호;이민화;민신홍;김신근;우종학
    • YAKHAK HOEJI
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    • v.14 no.1_2
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    • pp.28-35
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    • 1970
  • The absorption of Aminopyrine from the small intestine of a rat in combination with antihistamic agent, Diphenhydramine, Pheniramine, Tripelennamine and Diphenhydramine respectively, was examined. Through the rat small intestine canal, a definite quantity of a sample solution comprising 0.5 mM of Aminopyrine and 0.1 mM of each antihistamic agent in phosphate buffer solution (pH=7.4) was perfused through the rat small intestine at rate 5 ml per minute. The samples of the circulating solution were taken out after 5 minutes of the perfusion to give initial concentration and every 30 minutes for 3 hours. The amount of residual Aminopyrine in the solution was determined photometrically at 720 m.mu. by using 0.4% potassium ferricyanate solution and 1% ferric nitrate in 0.1N nitric solution. The mixed compounds of Aminopyrine with antihistamic agent, such as Aminopyrine with Diphehydramine, Aminopyrine with Pheniramine, Aminopyrine with Tripelennamine and Aminopyrine with Chloropheniramine showed more increased absorption than Aminopyrine alone. the absorption rate constants and apparent permeability coefficients of the mixed compounds were shown in detail.

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Clostridium perfringens type A associated enteritis in a Shitzu dog

  • Byun, Jae-Won;Yoon, Soon-Seek;Lim, Suk-Kyung;Lee, O-Soo
    • Korean Journal of Veterinary Service
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    • v.29 no.4
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    • pp.497-501
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    • 2006
  • Acute hemorrhagic enteritis was diagnosed in a seven-month-old male Shitzu dog dying of blood stained diarrhea and vomiting. Clinical findings were anorexia, dullness and sudden death after massive bloody diarrhea. At necropsy, main lesion was the hemorrhage in small intestine, mainly duodenum and jejunum. Microscopically, Gram positive long bacilli were massively detected on the mucose epithelial cells and necrotic debris of small intestine. Coagulative necrosis of epithelial cells and thrombosis of small intestine were also identified. However, there was no lesion of crypt epithelium. Mineral infiltration in both gastric mucosa and renal tubules was detected and proliferation of fibrous tissue was also shown in corticomedullary regions. In bacterial examination, C perfringens was isolated in anaerobic culture and it was confirmed to type A by multiplex PCR. Therefore, the dog was diagnosed as C perfringens type A associated enteritis with uremia.

A Review on Seperation of the Clear[淸] and Turbid[濁] in Large & Small Intestine (대소장(大小腸) 비별청탁(泌別淸濁)에 관(關)한 고찰(考察))

  • Song, Ji-Chung;Keum, Kyung-Soo;Eom, Dong-Myung
    • Journal of Korean Medical classics
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    • v.23 no.2
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    • pp.225-233
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    • 2010
  • Conceptions about functions of large & small intestine[LI & SI] were focused on the vermiculation in "Somun(素問) Yeongranbijeonron(靈蘭秘典論)". However, functions of large & small intestine includes more. In Oriental Medicine, there are sentences in "Hwangjenaegyeong(黃帝內經)" "LI manages Fluid [津] and SI manages Humor[液]" It means that LI & SI have an each role in digestion besides vermiculation. In that reason, we try to find out the meaning of the functions of LI and SI in digestion through bibliographic review. As a result, LI and SI have a digestic function by Separating the Clear which includes Fluids and Humor and the Turbid which is relatively useless to the Clear.