• Title, Summary, Keyword: Serum lipid

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The Effect of Ginseng Extracts on Photooxidation in Serum Lipid (혈청지질의 광산화 반응에 미치는 인삼추출물의 영향)

  • 백태홍;천현자
    • Journal of Ginseng Research
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    • v.13 no.2
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    • pp.234-238
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    • 1989
  • In the presence of a photosensitizer, rose bengal, phooxidatlon in serum total lipids has been studied and the effects of ginseng water extract and saponins on it have reviewed. In the presence of rose bengal, serum total lipids undergo photooxidation and produce lipid hydroperoxides. On the other hand, ginseng water extract and dial saponins largely inhibit photooxidation and decrease the amount of lipid hydroperoxides in serum total lipids.

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Quality of Sleep and Serum Lipid Profile in Patients with Restless Legs Syndrome (하지불안증후군 환자의 수면의 질과 혈청지질 농도)

  • Bak, Yeon-Gyung;Park, Hyoung-Sook
    • Journal of Korean Academy of Nursing
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    • v.41 no.3
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    • pp.344-353
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    • 2011
  • Purpose: The purpose of this study was to compare the quality of sleep with the serum lipid profile in patients who have restless legs syndrome (RLS). Methods: The data were obtained from 116 patients with RLS through questionnaires and blood sampling. Results: The results of this study showed correlations between lower quality of sleep and serum lipid profile (LDL Cholesterol) in patients with RLS (r=.19, p=.040). There were correlations for scores of quality of sleep from the, Pittsburgh Sleep Quality Index (PSQI) sub-region between lower subjective sleep quality and serum lipid profile (LDL Cholesterol) (r=.20, p=.026), between fewer hours of sleep duration and serum lipid profile (Total Cholesterol) (r=-.21, p=.024), and, between higher daytime dysfunction and serum lipid profile (LDL Cholesterol) (r=.42, p<.001) of patients with RLS. Conclusion: Pati-ents with RLS have sleep disorders with lower quality of sleep and changes in the serum lipid profile for total cholesterol and LDL cholesterol. That is, patients with RLS have lower quality of sleep and dyslipidemia compared to persons without RLS. Further research is needed to monitor serum the lipid profile in early stage symptoms of midlife adult patients with RLS and especially older women.

A Study of Serum Lipid in Korean (한국인(韓國人)의 혈청지질(血淸脂質) 연구(硏究))

  • Lee, Soo-Young;Kim, Kang-Seuck
    • Journal of Korean Life Insurance Medical Association
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    • v.2 no.1
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    • pp.101-115
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    • 1985
  • In Med Dept. Daehan Education Insurance, Total 690 cases(male 376 cases, female 314 cases) were inspected to study the change of serum lipid value. The objects of investigation were total cholesterol, HDL cholesterol, triglyceride, phospholipid and total lipid value. The results are as follows: 1) In the normal subjects, with the relation of serum lipid value and the age. triglyceride, phospholipid and total lipid value showed the increasing tendency by 70 age, but total cholesterol value and HDL cholesterol value showed the increasing tendency by 59 age and the decreasing tendency after 59 age. 2) In the normal subject the difference of serum lipid value between sexes did not make the significant difference of level statistically in all items which can be inspected. 3) The weight change and serum lipid value are very significantly related. Total cholesterol, HDL cholesterol and total lipid value are high in female if the weight is light. But they are high in male the weight is heavy phospholipid value is opposite to the above result. Triglyceride value is high in male regardless the weight, but the significant difference happened in the high weight group. 4) As serum lipid value of hypertension patients is compared with that of the normal subjects, HDL cholesterol, triglyceride, phospholipid and total lipid value are significantly high. 5) The doubtful group of the fatty infittration of liver among the hypertension pafients have very significant difference in serum lipid value compared with not only the value of the normal subject but also that of the obesity group. 6) The doubtless group of the fatty infitration of liver among the hypertension patients have the significant difference in all serum lipid value compared with that of the normal subject, but compared with the obesity group males had the significant difference of HDL cholesterol value and both sexes had the significant difference in total lipid value, but had no significant difference in total cholesterol, triglyceride and phosprolipid value. 7) The ratio of total cholesterol per HDL cholesterol had the significant difference in the doubtful hypertension patients of the fatty infittration of liver and the relative weight, but it had no significant difference compared with the normal subject in the doubtless hypertension patients.

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Effect of Mulberry Fruit Tea on the Serum Lipid Profiles and Cardiovascular Disease Markers of Middle-Aged People Living in Choongnam (오디 분말차 급여가 일부 충남지역에 거주하는 중년 남.녀의 혈청 지질 및 심혈관계 인자에 미친 영향)

  • Kim Ae-Jung;Yuh Chung-Suk;Bang In-Soo
    • Journal of the East Asian Society of Dietary Life
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    • v.16 no.4
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    • pp.408-413
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    • 2006
  • This study was conducted to examine the effects of mulberry fruit tea (MFT) on the levels of serum lipid profiles and serum cardiovascular disease markers in sixty middle-aged people(30 males and 30 females) who consumed MFT for 4 weeks. Anthropometric measurements, serum lipid profile levels, and serum cardiovascular disease markers were analyzed before and after consumption of MFT. After consumption of MFT, no significant differences were observed in anthropometric measurements, levels of serum aspartate transaminase (AST) and alanine transaminase (ALT) in males and females. Among serum lipid profiles, triglyceride and LDL-cholesterol were decreased significantly, whereas HDL-cholesterol was significantly increased.

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Serum glucose and lipid profiles according to dietary carbohydrate and lipid intake ratio in NIDDM patients (인슐린 비의존성 당뇨환자의 탄수화물과 지질섭취비율이 혈당과 지질성상에 미치는 영향)

  • 조우균
    • Journal of the Korean Home Economics Association
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    • v.36 no.11
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    • pp.183-191
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    • 1998
  • This study aimed at the effect on serum glucose and lipid profiles according to carbohydrate / lipid intake ratio in Korean 191 NIDDM patients. Most of NIDDM patients belong to under 50-64 years. As carbohydrate intake level increased, lipid intake level decreased. The group of higher carbohydrate / lipid intake ratio shows significantly high in fasting glucose level and postprandial glucose in NIDDM patients. The higher carbohydrate / lipid intake ratio the higher dietary linoleic and $\omega$-3 fatty acid level but not in dietary $\omega$3/$\omega$6 ratio. Serum HDL decrease inhigher carbohydrate lipid intake ratio group. Serum total lipid and PUFA level decrease according to ditary total lipid intake decrease in men but not significantly different.

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Studies on Lipid Intake, Serum Lipid Profiles and Serum Fatty Acid Composition in College Women Who Smoke (흡연여대생의 지질섭취와 혈중지질 및 지방산 조성에 관한 연구)

  • 안홍석;이금주;김나영
    • Korean Journal of Community Nutrition
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    • v.7 no.1
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    • pp.102-110
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    • 2002
  • Cigarette smoking has long been recognized as a major risk factor in the development of coronary heart disease. Several investigators have reported the strong association between smoking and high serum cholesterol, triglyceride concentration, SFA and low HDL cholesterol, PUFA and $\omega$6 concentrations. Therefore, this study was done to investigate the effect of smoking on the serum lipid profile and fatty acid composition of college women. Sixty-one non-smokers and twenty-seven smokers were selected from college women students in the Seoul area. Their lipid intake, serum lipid concentration and fatty acid composition were examined. There were no differences in the general characteristics and anthropometric indices between the smokers and non-smokers. However, alcohol consumption was significantly higher in smokers than non-smokers (p<0.001). The daily caloric intake of smokers and non-smokers were 1875.84 kcal and 1915.53 kacl, respectively. On the other hand, the mean daily intake of lipids and cholesterol were significantly lower in smokers (p<0.05). In smokers, the mean concentrations of serum total cholesterol, LDL-cholesterol and the LDL-C/HDL-C ratio were higher, and the compositions of EPA and DHA were lowe than in non-smokers. There was a negative correlation between the serum triglyceride and PUFA levels in the two groups. Also, serum HDL-C correlated negatively with MUFA in smokers and non-smokers (p<0.01). These results suggest that smoking cause inadequate changes in serum lipid profile and serum fatty acid composition, thereby increasing the tendency for coronary heart disease.

Factors Affecting Serum Lipids in Maternal and Infants Umbilical Cord Blood (산모혈과 제대혈의 혈청 지질치에 영향을 미치는 요인에 대하여)

  • 민재희;정규혁;연제덕
    • Journal of Environmental Health Sciences
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    • v.23 no.3
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    • pp.66-71
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    • 1997
  • To investigate the effect of several factors on serum lipids in maternal and infants umbilical cord blood, 111 cases of newborn infants and women delivered of a child who had delivered at hospital located in Chung-Ju city from Feb. 1, 1996 to Aug. 31, 1996 were studied. The gestational ages of cases were 37 to 42 weeks and the average maternal ages were 28.1$\pm$4.25 years old without any other medical or obstetric problems. No relationships between maternal consumption of coffee and maternal serum lipid levels were observed. However, serum total cholesterol and LDL-cholesterol levels in infants'umbilical cord were significantly increased in proportion to increasing maternal consumption of coffee. The other factors such as alcohol drinking habits and residency affected maternal serum lipid levels and not serum lipid levels in infants' umbilical cord. Delivery frequency showed very little or no effects on serum lipid levels in both maternal blood and infant's umbilical cord blood. In conclusion, maternal consumption of coffee significantly correlated with increasement of serum lipid levels in infants'umbilical cord.

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Effects of Polyacetylene Compounds from Panax Ginseng C.A. Meyer on $CCl_4$-Induced Lipid Peroxidation in Mouse Liver

  • Kim, Hye-Young;Lee, You-Hui;Kim, Shin-Il
    • Toxicological Research
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    • v.4 no.1
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    • pp.13-22
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    • 1988
  • The inhibitory effect of three polyacetylene compounds, panaxydol, panaxynol and panaxytriol isolated from Panax ginseng C.A. Meyer on $CCl_4$induced lipid peroxidation in vivo and in vitro hepatic microsomal lipid peroxidation induced by ADP-$Fe^{3+}$, NADPH and NADPH-cytochrome P-450 reductase were investigated. Their effects on lowering the lipid peroxide levels both in serum and liver and lowering the serum enzyme (GOT, GPT, LDH) activities without the $CCl_4$-induction were also determined. Male ICR mice were pretreated i.p. with polyacetylene compounds or DL-${\alpha}$-tocopherol before administration of $CCl_4$ i.p. and 20 hr after the administration of $CCl_4,$ serum and liver were analyzed. Hepatic microsome was isolated and used for the in vitro NADPH-dependent lipid peroxidation system. Except for panaxynol, treatment with polyacetylenes to control mice did not reduce the levels of lipid peroxides and serum enzyme activities. Panaxynol itself inhibited lipid peroxidation in the liver of normal mice. Polyacetylene compounds protected from the $CCl_4$-induced hepatic lipid peroxidation and lowered serum lipid peroxide levels. Polyacetylenes also inhibited the in virto hepatic microsomal lipid peroxidation in a dose-dependent manner. The results suggest that panaxydol, panaxynol and panaxytriol seem to be the antioxidant components which contribute the anti-aging activities of Panax ginseng C.A. Meyer.

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Quantitative Determination of Lipid Hydroperoxide in Human Blood Serum by Ferrothiocyanate Method (Ferrothiocyanate법에 의한 혈청 Lipid Hydroperoxide정량)

  • Paik, Taik-Hong;Park, Chan-Sik;Chun, Hyun-Ja
    • Journal of the Korean Applied Science and Technology
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    • v.5 no.1
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    • pp.25-30
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    • 1988
  • In order to develope the method of quantitative determination of lipid hydroperoxide in human blood serum, we tried the ferrothiocyanate method to total lipids extracted by Bligh-Dyer method and obtained the results as follows. 1. The maximum absorbance showed at the concentration of Mohr's solution, 0.127M at pH 1.70 and ammonium thiocyanate solution, 3.95M in the ferrothiocyanate method. 2. When hydrogen peroxide, cumene hydroperoxide, and oxidized linoleic acid were added to serum, and extracted them by Bligh-Dyer method to examine the extraction efficiency, we confirmed that cumene hydroperoxide and oxidized linoleic acid were extracted in $CHCI_3$ phase, and hydrogen peroxide in $MeOH-H_2O$ phase, respectively. 3. The concentration of lipid hydroperoxide of total lipids extracted from normal adult serum was $2.0{\times}10^{-5}M$, and increased proportionally the concentration of lipid hydroperoxide by increasing the amount of serum. 4. When we compared the total lipids extracted by Bligh-Dyer method and total lipids extracted after lipoprotein is precipitated by Yagi method in human blood serum, the concentration of lipid hydroperoxide was showed nearly the same value. From our results, we concluded that the concentration of lipid hydroperoxide in human blood serum could be determined quantitatively by ferrothiocyanate method.

Dietary Fat Intake during Pregnancy and Serum Lipid Levels in Mother and Umbilical Cord of Full-term and Preterm Delivery (만기분만의 조기분만 산모의 임신중 지방섭취와 모체 및 제대혈청의 지질농도)

  • 박성혜
    • Journal of Nutrition and Health
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    • v.32 no.5
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    • pp.577-584
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    • 1999
  • The correlation between maternal lipid nutritional status during pregnancy and gestational length was investigated. Subjects consisted of 30 full-term delivery mothers, 30 preterm delivery mothers, and babies of both groups. Dietary fat intake during pregnancy and serum lipid levels in mother and umbilical serum were measured. The mean daily intake levels of fatty acid during pregnancy were lower than the recommended dietary allowances, while $\omega$6/$\omega$3 ratios of dietary fatty acids were acceptable. For preterm delivery mothers, fatty acid intake levels to be lower than those in full-term delivery mothers, especially DHA intake of these two groups was significantly different. During gestation, hyperlipidemia was apparent in the pregnant women. The serum lipid contents of preterm delivery mothers tended to be lower than those of full-term delivery mothers, and umbilical cord serum lipid contents of the preterm delivery group tended to be higher than those of the full-term delivery group. Total cholesterol levels in the umbilical cord serum of preterm babies were significantly higher than those of full-term delivery group. On the other hand, total cholesterol and HDL-cholesterol levels between umbilical cord serum and maternal serum were positively correlated in the preterm delivery group. Concerning, energy and fatty acid intakes were more closely associated with umbilical cord serum lipid levels in full-term babies, but negatively associated in preterm babies. It was concluded that gestational length was related to the dietary intake of fatty acids such as DHA in pregnant women. For better understanding, the ralationship between placental lipid transport mechanisms and gestational length needs to be explored.

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