The the FSB concept is modified and new type of hybrid energy dissipation device, the Active Friction Slip Braces (AFSB), is described. The FSB is by far improved in the AFSB by inclusion of an active clamping mechanism on the friction interface. The results of Single-Degree-of Freedom(SDOF) structure have indicated that the action of dissipating vibrational energy in the AFSB impacts on the response at later cycles by keeping the drift amplitudes at much lower levels, revealing overshooting problem due to its early slippage, and the problem has been taken cared by modifying the algorithm successfully shown in the previous publication in December 2016. It has also shown that providing predetermined constant incremental strengths to the building by AFSB members with the proposed algorithm for a SDOF structure has improved the responses by reducing drift amplitudes and base shear under small and medium amplitude ground accelerations. In this study, the algorithm is tested on the Multiple-Degree-of-Freedom(MDOF) structure to verify the effectiveness of AFSB supplemented by the algorithm. A six story steel building which is the prototype building for part of the US-Japan Corporative Research Program is selected as an example building. The building is designed and modeled as an FSB and ASFB building, and subjected to a series of ground motions. The response envelopes of both buildings are obtained and compared to evaluate the design implication of AFSB applications.