For realizing ubiquitous computing, many research activities are geared towards various areas including embedded computing, RFID, USN, home networking, context-awareness, and etc. By using the ability of RFID technology to recognize a number of objects simultaneously, more convenient ubiquitous application services are effectively provided. In this case, RFID middleware playing a role as a bridge between RFID reader devices and application services is required as well. In this paper, we propose a method of handling a number of types of RFID reader devices in ALE middleware of EPCglobal. For this, the information of connection and data protocol for a reader device is stored in a database as ontology meta-data, and used to interpret the data read by a reader device. By adding ontology data into a database, even though an RFID device newly emerges, ALE middleware can not only handle the device, but also be effectively extended through reusing ontology data, without any changes in the middleware.