• Title, Summary, Keyword: RCT

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The quality of Reports on Randomized Controlled Trials abstracts from Korean Science Citation Index journal and NEJM; Evaluation and Comparison of adherence to the CONSORT Statement (CONSORT statement를 기반으로 한 국내 Science Citation Index 저널과 NEJM의 Randomized Controlled Trial의 abstracts 질적 비교 평가 연구)

  • Kyung, Eun-Jung;Kim, Hyo-Seon;Kim, Eun-Young
    • Korean Journal of Clinical Pharmacy
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    • v.22 no.2
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    • pp.131-136
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    • 2012
  • Objective: This study evaluated and compared the adherence to the CONSORT for quality of reports on the randomized controlled trials (RCT) abstracts by four major Korean Science Citation Index (SCI) journals and The New England Journal of Medicine (NEJM). Methods: A descriptive analysis of published RCT abstracts in Korean SCI journals and NEJM from 2007/01 to 2011/06 was conducted by two reviewers, independently extracting data from a PubMed search. A modification of CONSORT for abstract was used including 16 checklist items. Reporting of checklist items for individual group was conducted to compare adherence patterns between two groups. Results: We identified the potential 57 RCT abstracts from Korean SCI and 50 from NEJM meeting our inclusion criteria; among them, three abstracts from Korean SCI and one from NEJM were excluded. Among total 16 checklist items based on CONSORT statement, Korean SCI journals and NEJM were statistically equivalent in 4 items; Korean journals were better in three items and NEJM were in nine. The methodological quality domains were inadequately reported in both journals: allocation concealment about 1.9% and 4.0%, and blinding 44.4% and 40.8%. In general, The CONSORT adherence of NEJM was better than that of Korean SCI in the method and result domain (p < 0.0001). Conclusions: The quality of NEJM reporting of RCT abstracts was better than that of Korean SCI, in general. This study on adherence of RCT reports from Korean SCI journals and NEJM abstracts to the CONSORT statement reveals that there is a need for improvement, especially Korean SCI. Further investigation on the quality of RCT reports and ways to improve reporting quality is required.

Effect of Cubed Roughage Supplementation and Red Clay Levels on Growth Performance, Meat Quality and Economic Benefits in Korean Native Cattle (양질 조사료의 보충과 황토의 첨가수준이 한우의 성장성적, 육질 등급 및 경제성에 미치는 영향)

  • Jin, Y.H.;Jin, M.G.;Hong, J.S.;Lee, H.G.;Lee, B.K.;Kim, J.S.;Choi, Y.J.
    • Journal of Animal Science and Technology
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    • v.44 no.1
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    • pp.61-68
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    • 2002
  • This study was conducted to estimate the effects of high quality cubed roughage and red clay (0%, 1%, 2%) on growth performance, meat quality and economical benefits. Thirty-six 6 month-old Korean native cattle, averaging 156kg of BW, were assigned to six groups in a 2 (rice straw : RT, rice straw+cubed roughage : RCT) ${\times}$ 3 (0, 1, 2% red clay). During experimental period, the high quality cubed roughage added into rice straw treatment (RCT) was superior to the only rice straw treatment (RT) on daily gain and feed efficiency and final weight 10%, 6.8%, 8.2% (P$<$0.05) respectively. But the addition of red clay did not affect and even 2% addition decreased those parameters. For meat quality and economical analysis, the addition of high quality cubed roughage made an outstanding result and for RT treatment, only 1% red clay indicated good effects while both 1% and 2% red clay were better than 0% for RCT treatment. From these results, it is assumed that the addition of red clay for fattening Korean native cattle has no effects on growth performance but 1% treatment has good results on improving meat quality and economical benefits. It also suggests that the combination high quality roughage and concentrated red clay is beneficial for producing high quality meat in with economical benefits.

Analysis of New Patient's Willingness to Pay Additional Costs for Securing Satisfactory Consultation Time (외래 초진환자의 만족진료시간과 관련 추가 비용 지불 의사)

  • Lee, Chan Hee;Lim, Hyunsun;Kim, Youngnam;Yoon, Soojin;Park, Yang Sook;Kim, Sun Ae;Park, Eun-Cheol;Kang, Jung-Gu
    • Health Policy and Management
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    • v.27 no.1
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    • pp.39-46
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    • 2017
  • Background: We evaluated new patient's satisfactory consultation time (SCT) and their willingness to pay additional costs (WPAC) for their SCT. Methods: We surveyed medical service satisfaction, SCT, WPAC for their SCT, and payable amount to 612 new patients of single general hospital and measured their real consultation time (RCT). To compare WPAC and payable amount, we divided RCT into 4 groups (${\leq}3$ minutes, 3-5 minutes, 5-10 minutes, and > 10 minutes), and SCT into 3 groups (${\leq}5$ minutes, 5-10 minutes, and > 10 minutes). On the basis of WPAC, we estimated new patient's SCT. Results: RCT was 6.2 minutes, SCT was 8.9 minutes, and medical service satisfaction score was 4.3 (out of 5). The number of patients having WPAC (payable group) was 381 (62.3%) and the amount was 5,853 Korean won. Their RCT and SCT were longer than non-payable group (6.4 minutes vs. 5.7 minutes, 9.3 minutes vs. 8.2 minutes). From multiple logistic regression analysis, WPAC of RCT 5-10 minutes was higher than that RCT ${\leq}3$ minutes (odds ratio= 1.78). Payable amount was highest in RCT > 10 minutes (6,950 Korea won) and SCT > 10 minutes (7,458 Korean won). Intuitively we suggest 10 minutes as SCT, based on payable group's SCT (9.3 minutes) and cut-off time differentiating payable group with non-payable group (10 minutes). Conclusion: We found that new patient had WPAC for their SCT and the longer the SCT, the greater the amount. From this, we hope that current simplified new patient consultation fee calculating system should be modified combining the consultation time factor.

A Review of Dysmenorrhea Related Articles in Literature of Oriental Medicine (한의학 관련 학회지의 월경통 관련 논문에 대한 종설)

  • Kim, Dong-Il
    • The Journal of Korean Obstetrics and Gynecology
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    • v.21 no.1
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    • pp.134-149
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    • 2008
  • Purpose: Dysmenorrhea is a common gynecologic condition among reproductive-age women. It consisted with menstrual clamps and other symptoms such as nausea. vomiting, diarrhea, and fatigue. Pain control for this disease mainly through NASIDs. but recently CAM therapies, acupuncture and others for painful menstruation are widely used in western countries. But RCT articles about dysmenorrhea in Korea, are not enough to lead such global research trends. The purpose of this study is to review treatment method and other research tendency about dysmenorrhea in Korean Medicine(KM) related dominant journals. Methods: Searching was done through web site and directly searched dysmenorrhea related articles in journals of Korean medicine Gynecology, published during 1996-2007. Results: Twenty five articles were searched in KM related journals, then two of them were simple case report and ten were paper of clinical trials. But there no RCT or control group-designed study. All of them present positive effect on dysmenorrhea but drop out rates were relatively high. Conclusion: KM therapies including acupuncture and herbal medicine have some beneficial effect to resolve menstrual cramps, but KM therapy related Korean articles don't have strong objective power as a evidence in the viewpoint of EBM. So continuous clinical trials such as RCT and multi center trials are needed.

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Investigation on the 12 Phases of Hero's Journey in RCT3 Game Story (RCT3 게임스토리에 나타난 영웅의 모험(Hero's Journey)의 12가지 단계)

  • Roh Chang-Hyun;Lee Wan-Bok
    • Proceedings of the Korea Contents Association Conference
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    • pp.64-69
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    • 2005
  • Recently, grafting of a story into a game has attracted ever increasing attention. In this study, the 12 phases of Hero's Journey by Joseph Campbell highlighted in movies and myths was analysed from a point of Christoper Vogler to be correlated with a game. Since a story-teller Is a player in a game, the story experienced by the player enjoying the game was examined and correlated with the 12 phases of Campbell. As the game, a construction/management simulation game, RCT3 produced by Atari was studied. The 12 phases of Campbell was applicable to game story.

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A Review of Ovarian Cyst Management in Oriental Medicine (난소낭종에 대한 한의 임상 연구의 종설)

  • Kim, Dong-Il
    • The Journal of Korean Obstetrics and Gynecology
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    • v.20 no.4
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    • pp.175-190
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    • 2007
  • Purpose: Ovarian cysts are fluid-filled sacs or pockets within or on the surface of an ovary. Most cysts present little or no discomfort and are noncancerous and harmless. So non-surgical treatments with herbal medicine or acupuncture and moxa therapy are important and suitable in this pathology. But there are few RCT articles about ovarian cyst in Korean Medicine(KM) clinical and research field. Methods: To review treatment method and other research tendency about ovarian cyst in journals related with KM and Traditional Chinese Medicine(TCM) through web-searching. Searching was done through web site #http://omis.ksucc.ac.kr# and pub-med(http://www.ncbi.nlm.nih.gov/sites/entrez) with key words #ovarian cyst#, #TCM#, #herb#, #CAM#, and #acupuncture#. Results: Seven articles were searched in journals related with KM, then six of them were simple case report and the other one was about diagnosis for ovarian cyst and another gynecologic disease such as uterine myoma and infertility through the iris diagnosis. And two articles were searched in journals related with TCM, then one of them was simple case report but the other is RCT article. Conclusion: KM and TCM therapies have some beneficial effect to resolve cyst, but objective power as a evidence is weak in the viewpoint of EBM. So continuous clinical trials such as RCT and multi center trials are needed.

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Ginseng for managing menopause symptoms: a systematic review of randomized clinical trials

  • Kim, Myung-Sunny;Lim, Hyun-Ja;Yang, Hye Jeong;Lee, Myeong Soo;Shin, Byung-Cheul;Ernst, Edzard
    • Journal of Ginseng Research
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    • v.37 no.1
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    • pp.30-36
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    • 2013
  • The aim of this review was to assess the effectiveness of ginseng as a treatment option for managing menopause symptoms. We searched the literature using ll databases from their inception to 26 September 2012 and included all randomised clinical trials (RCTs) that compared any type of ginseng to a placebo controls in postmenopausal women. The methodological quality of all studies was assessed using a Cochrane risk of bias tool. Four RCTs met our inclusion criteria. Most RCTs had high risk of bias. One RCT showed that Korean red ginseng (KRG) significantly improved sexual arousal and global health compared with placebo. Another RCT reported the superiority of KRG over placebo for treating menopause symptoms on Kupperman's index and menopausal rating score. The third RCT failed to show a significant effect of KRG on hot flash frequency compared to placebo. The fourth RCT found beneficial effects of ginseng compared to placebo on depression and well-being. In conclusion, the evidence on ginseng as an effective treatment for managing menopause symptoms is limited. Most of the RCTs are burdened with a high risk of bias. Thus firm conclusions cannot be drawn. Rigorous studies seem warranted.

Recent Research Trends in Moxibustion Treatment in Korea

  • Lee, Ju-Hyeon;Hwang, Doo-ree;Hong, Seung-Hyo
    • Journal of Acupuncture Research
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    • v.37 no.1
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    • pp.1-12
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    • 2020
  • A total of 1,235 studies were retrieved on June 23, 2019, from 3 databases. Selected 59 studies were evaluated by year of publication, study type, subject condition/disease, acupoint, standards for reporting interventions in clinical trials of moxibustion (STRICTOM), Cochrane risk of bias (RoB), and risk of bias assessment tool for non-randomized study (RoBANS). Most studies were conducted in 2011, after which the number of studies decreased. The most common study type was 25 case reports (CR), 16 uncontrolled clinical trials (UCT), 11 randomized controlled trials (RCT), and 7 controlled clinical trials (CCT). Moxibustion treatment was mainly used for musculoskeletal and circulatory diseases/conditions. A total of 83 acupoints were used, A-shi points being the most used. As for STRICTOM, an average of 7.4 items were satisfactory for UCT and CR without a control group, and an average of 9.4 items were satisfactory for RCT and CCT. RCT was assessed using the RoB, and many items were rated as uncertain. In this study, the need for RCT of moxibustion treatment in Korea was identified. The detailed description of study methods and results will provide evidence for the efficacy of moxibustion treatment in preventive and therapeutic aspects of Korean traditional medicine.

Ultrasonographic Evaluation of Renal Cortex and Outer Medulla Thickness in Dogs with Chronic Kidney Disease

  • Lee, Siheon;Hong, Sungkyun;Kim, Hyejin;Oh, Dayoung;Kim, Seungji;Choen, Sangkyung;Choi, Mincheol;Yoon, Junghee
    • Journal of Veterinary Clinics
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    • v.34 no.3
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    • pp.208-212
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    • 2017
  • This study was performed to retrospectively pursue any correlation between renal cortex thickness (RCT), outer medulla thickness (OMT) on ultrasonography (US) and chronic kidney disease (CKD) with International Renal Interest Society (IRIS) stage. Medical records and US findings of the dogs diagnosed CKD were reviewed for comparing to those of the clinically healthy dogs from March. 2015 through June. 2016. To evaluate the correlation about normal and CKD patients, RCT and the OMT were measured on US images. RCT and OMT were adjusted by dividing body surface area for standardization (RCTS, OMTS). Also the ratio of RCT/OMT were calculated and these indices were evaluated to investigate any tendency between 5 groups (normal and 4 IRIS stages) using Jonckheere-Terpstra trend test (J-T test). The RCTS showed a declining tendency (p < 0.02) and the OMTS showed an inclining tendency from normal through each IRIS stage (p < 0.01). The RCT/OMT showed also declining tendency (p < 0.01). Although the gold standard for renal function including GFR is lack, it is thought that differentiation between normal and CKD patients could be possible on US measurement of renal cortex and outer medulla thickness, which could be an alternative index for kidney function in diagnostic imaging.

Research Trends and Quality Evaluation of Family Nursing Interventions Outside Korea (국외 가족간호중재 연구의 현황과 질 분석)

  • Oh, Ka-Sil;Ahn, Hyun-Mi;Ra, Jin-Suk;Cho, Eun-Young
    • Journal of Korean Academy of Community Health Nursing
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    • v.20 no.4
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    • pp.421-432
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    • 2009
  • Purpose: This study investigated trends in family nursing intervention studies and evaluated the quality of studies using the RCT design. Methods: This study included a total of 898 abstracts published from 1977 to 2007 in order to describe trends in family nursing intervention studies. Out of 898 studies, 153 RCT studies were selected for quality evaluation. The criteria of Jadad et al. (1996) were employed for the quality evaluation. Results: The number of RCT studies on family nursing interventions increased since 2001. Only 6.8% of the studies were published in the area of nursing. Most of the family interventions (27.1%) focused on individual family members and only 8.2% of the studies provided interventions to family as a whole unit. Nine different modes of family nursing intervention could be categorized, but none of the studies used the double blind design. Few studies utilized protocols for interventions. Only 17.5% of the studies reported the rationale for sample size. The mean score was 1.6 out of 5 according to the criteria of Jadad et al. (1996). Conclusion: Refined definitions and attributes of family nursing intervention modes are needed. Most of the studies did not meet the expectations of RCT. Thus, it is needed to improve the quality of design. More RCT studies should be conducted to provide evidence-based practice of family nursing interventions.

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