• Title, Summary, Keyword: Personal care products

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HYDROPHILICALLY AND LIPOPHILICALLY MODIFIED PERFLUOROPOLYETHERS AS INGREDIENTS OF NON-CONVENTIONAL COMPOSITIONS

  • Giovanni Pantini;Rossellr Ingoglia;Solvay Solexis
    • Proceedings of the SCSK Conference
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    • pp.327-337
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    • 2003
  • In recent years, the chemical modification of polymers has been a driving force in many industrial sectors. There was evidence that this might also be the case of perfluoropolyethers (PFPEs) in the personal care industry. To investigate this potential, a systematic study has been conducted at Solvay Solexis SpA (formerly Ausimont SpA), through the analysis of the organic chemistry suitable to modify PFPE structures, and through the examination of the properties of PFPE derivatives thus produced from the viewpoint of a cosmetic formulator.(omitted)

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Determination of personal care products in aquatic environmental samples by GC/MS (GC/MS를 이용한 수질환경시료 중 personal care products의 분석)

  • Lee, In-Jung;Lee, Chul-Gu;Heo, Seong-Nam;Lee, Jae-Gwan
    • Analytical Science and Technology
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    • v.23 no.5
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    • pp.477-484
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    • 2010
  • Personal care products are a diverse group of synthetic organic chemicals such as antimicrobial compounds, UV filters and organo-phosphate flame retardants and derived from individual usages of soaps, toothpaste and cosmetics. It has been detected in municipal sewage effluent and various environmental samples such as surface water, marine, soil, sediment and aquatic biota in many countries. The occurrence of personal care products in environmental samples could negatively impact the health of the ecosystem and humans, due to persistent, long-term chronic exposure of aquatic organisms. In this study, fifteen personal care products in aquatic environmental samples were determined by gas chromatography-mass spectrometry (GC-MS) with liquidliquid extraction (LLE). Method detection limits were in the range of $0.004\sim0.273\;{\mu}g/L$. Two compounds (TCEP, TCPP) were detected in surface waters and seven compounds (triclosan, 4-MBC, EHMC, BP-3, TCEP, TPP, TBEP) were detected in sewage treatment plants (STP) influents or effluents.

Screening of the Antibacterial Activity of Natural Products aganist Propionibacterium acnes (Propionibacterium acnes에 대한 천연물의 항균효과 검색)

  • Choi, Seung-Man;Kim, Min-Joo;Choi, Young-Ho;Ahn, Ho-Jung;Yun, Yeo-Pyo
    • YAKHAK HOEJI
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    • v.42 no.1
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    • pp.89-94
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    • 1998
  • Propionibacterium acnes is the pharmacological target site of antiacne drugs. We have examined the antiacne activity of ninety seven natural products which have been used as Korean traditional medicines in various skin disorders. The antibacterial activity of extracts from the natural products were evaluated against P. acnes ATCC 9616 by disc method. Twelve natural products showed the potent antibacterial activity against P. acnes, and were, selected for the minimal inhibitory concentration(MC) against P. acnes. MICs of nine extracts were below 0.3% (w/v) and Sophora flavescens showed the most potent activity with a MIC of less than 0.008%(w/v) against P. acnes. Thus, the results suggest that nine natural products including S. flavescens can be developed as sources of promising potent antiacne agents.

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Analysis of Distribution of Propylene oxide in Nonionic Surfactant and Fatty alcohol by Reversed Phase High Performance Liquid Chromatography (역상 액체 크로마토그래피에 의한 비이온 계면활성제의 Propylene oxide 분포 및 Fatty alcohol의 분석)

  • Lee, Yong-Hwa;Bak, Hong-Soon;Choi, Kyu-Yeol;Lee, Jae-Duk;Ahn, Ho-Jeong
    • Applied Chemistry for Engineering
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    • v.8 no.2
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    • pp.315-319
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    • 1997
  • In this study, the optimum analytical conditions for determination of distribution of propylene oxide in a nonionic surfactant and separation of fatty alcohols were investigated by Reversed Phase High Performance Liquid Chromatography. To analyse the distribution of propylene oxide (PO) and carbon chain length of a fatty alcohol, we derivatized samples for the purpose of using a UV detector. Also, we studied the influences of columns and mobile phase composition to obtain the optimum separation conditions. In our experiment, Waters Symmetry $C_8(3.9{\times}150mm)$ column was used. And the optimum condition were obtained by gradient elution with methanol and water as the mobile phase. In the plot of log k' vs composition of water in the binary phase, the linerality was very good. We ploted the calibration curve to conform the quality of fatty alcohol, a good linerality was obtained.

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Antioxidative Activity of the Extracts from the Leaves and Fruits of Acer ginnala

  • Chung, Jin-Su;Lee, Min-Sun;Chung, Ji-Youn
    • Natural Product Sciences
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    • v.7 no.2
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    • pp.45-48
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    • 2001
  • The antioxidative effect of the extracts from the leaves and fruits of Acer ginnala against free radicals was studied by two different methods using DPPH radical-generating system, and hydroxyl radical-generating system $(Cu^{++}/H_2O_2\;system)$ which induces DNA strand breaking. Compared with well known antioxidative plants, green tea, Scutellaria baicalensis, the Acer ginnala extracts showed excellent radical-scavenging activity in DPPH radical-generating system and inhibited effectively hydroxyl radical induced-DNA strand breaking in a concentration-dependent manner in $Cu^{++}/H_2O_2$ system whereas the green tea extract stimulated the strand breaking at a low concentration. These results suggest that he extracts from the leaves and fruits of Acer ginnula could be good antioxidative agents.

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OBSERVATION OF THE SWEATING IN LIPSTICK BY SCANNING ELECTION MICROSCOPY

  • Seo, Su-Youn;Lee, In-Sook;Sin, Hyeon-Jong;Choi, Kyu-Yeol;Kang, She-Hoon;Ahn, Ho-Jeong
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.22 no.2
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    • pp.182-192
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    • 1996
  • In this study, the relationship between wax matrix in lipstick and sweating was investigated by observing the change of size and shape of wax matrix with sweating by Scanning Electron Microscopy (SEM). For observation by SEM, a lipstick sample was frozen in liquid nitrogen, then the oil in the lipstick was extracted out in cold isopropanol($-70^{\circ}C$) for 1-3days. After isopropanol was evaporated, the sample was sputtered with gold, and examined by SEM. When examined the sweated sample by SEM, the change of wax matrix underneath the surface from fine, uniform structure to coarse, nonuniform structure was observed, which was resulted from the caking of surrounding wax matrix. That is, the oil underneath the surface was migrated to the surface of lipstick with sweating, consequently the wax matrix at that region was rearranged into the coarse matrix. In case of flamed lipstick, sweating was delayed and the wax matrix was much coarser than that of unflamed one. Its larger wax matrix at surface region was good for including oil. The effect of molding temperature on sweating was also studied. As the molding temperature was increased, sweating was greatly reduced and the size of wax matrix was increased. It was also found that sweating was influenced with the compatinility of wax and oil. A formula consisting of wax and oil which have good compatibility has a tendency of reduced sweating and increased size of wax matrix. When pigment was added to wax and oil. It was also found that sweating was influenced with the passage of time by observing a thick membrane of wax on surface of lipstick after a month from molding. In case of some lipsticks, the size of wax matrix was altered to bigger or smaller. In conclusion, the structure of wax matrix at the surface region of lipstick was changed with the process of foaming, molding temperature, compatibility of wax and oil, addition of pigment, and the passage of time. In most cases, as the size of wax matrix was increased, sweating was reduced and delayed.

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Classification for a Standardization System for the Elderly's Necessities (고령친화용품 표준화를 위한 분류)

  • Kim, Yi-Soon;Kwon, Ja-Youn;Shin, Soon-Shik;Moon, In-Hyuk;Hwang, Lee-Cheol;Kim, Gyeong-Cheol
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.20 no.2
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    • pp.328-332
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    • 2006
  • This study aims to provide definitions and standardization for necessities that elderly people can use conveniently and properly in their daily lives and classify necessities for different purposes. First, standard terminologies were defined by reviewing the literature and the relevant laws related to daily necessities for the elders. Secondly, a concept for necessities for the elders was also defined through consultation with experts. Lastly, the elderly's necessities were selected and classified. The elderly's necessities are defined as aids that ordinary elderly people in normal aging process need for the purpose of the convenience of life and aids they wear or use to maintain or improve their health. In this study, the elderly's necessities are divided into three categories: necessities of health, necessities of Oriental medical aids and necessities of daily living. Each category is further classified as follows: Necessities of health include aids for personal medical treatment, aids for personal care and protection and aids for recreation. Necessities of Oriental medical aids include aids for personal medical treatment, aids for personal care and protection and others. Necessities of daily living include aids for personal care and protection, aids for personal mobility, aids for housekeeping, furnishings, aids for communication, information and signalling, aids for handling products and goods and aids for recreation. The classification of the elderly's necessities in this study can be used as basic information for further studies of demand for necessities for the elderly. The results will lay the foundation for a standardization system for the elderly's necessities and the development of silver industry.

Removal Characteristics of Endocrine Disrupting Compounds (EDCs), Pharmaceutically Active Compounds (PhACs) and Personal Care Products (PCPs) by NF Membrane (NF막을 이용한 EDCs, PhACs, PCPs 물질의 제거 특성 평가)

  • Jang, Hyuewon;Park, Chanhyuk;Hong, Seungkwan;Yoon, Yeomin;Jung, Jin-Young;Chung, Yun-Chul
    • Journal of Korean Society of Water and Wastewater
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    • v.21 no.3
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    • pp.349-357
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    • 2007
  • Reports of endocrine disrupting compounds (EDCs), pharmaceutically active compounds (PhACs), and personal care products (PCPs) have raised substantial concern in important potable drinking water quality issues. Our study investigates the removal of EDCs, PhACs, and PCPs of 10 compounds having different physico-chemical properties (e.g., molecular weight, and octanol-water partition coefficient ($K_{OW}$)) by nanofiltration (NF) membranes. The rejection of micropollutants by NF membranes ranged from 93.9% to 99.9% depending on solute characteristics. A batch adsorption experiments indicated that adsorption is an important mechanism for transport/removal of relatively hydrophobic compounds, and is related to the octanol-water partition coefficient values. The transport phenomenon associated with adsorption may also depend on solution water chemistry such as pH and ionic strength influencing the pKa value of compounds. In addition, it was visually seen that the retention was somewhat higher for the larger compounds based on their molecular weight. These results suggest that the NF membrane retains many organic compounds due to both hydrophobic adsorption and size exclusion mechanisms.

Mixture Toxicity of Methylisothiazolinone and Propylene Glycol at a Maximum Concentration for Personal Care Products

  • Park, Juyoung;Lee, Handule;Park, Kwangsik
    • Toxicological Research
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    • v.34 no.4
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    • pp.355-361
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    • 2018
  • Methylisothiazolinone (MIT) has been used in combination with methylchloroisothiazolinone (CMIT) for cosmetic products such as shampoo, body lotion, and skin care products. The mixture of CMIT/MIT has been found to cause allergic contact dermatitis and is thus no longer permitted for use as a preservative in leave-on cosmetics. However, MIT itself was approved as a stand-alone preservative at a maximum concentration of 100 ppm as the toxicity was derived from CMIT rather than MIT. However, in many countries, allergic skin irritation caused by MIT remains a social concern. In this study, skin irritation was assessed for the presence of MIT, propylene glycol, and their mixture using a 3D human skin model $EpiDerm^{TM}$. Although non-diluted MIT causes serious skin toxicity, skin irritation was not observed at a concentration of 100 ppm, the maximum permissible level for cosmetics and personal care products according to European regulations. Propylene glycol, the most widely used vehicle for MIT, did not cause skin irritation in the 3D skin model. The results are expected to provide information for regulatory policies and guidelines on the use of biocides in consumer products.

Determination of Preservatives in Pharmaceuticals and Personal Care Products (의약품 및 개인위생·생활용품 중 보존제 함유량 분석)

  • Kim, Boyoung;Lee, Joohee;Kim, Seonyeob;Lee, Eunji;Choi, Chorong;Kho, Younglim
    • Journal of Environmental Health Sciences
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    • v.42 no.1
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    • pp.53-60
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    • 2016
  • Objectives: Preservatives are commonly used in pharmaceuticals, cosmetics and other products to extend the expiration date and prevent the growth of microorganisms. Preservatives are generally effective in controlling mold and inhibiting yeast growth, and against a wide range of bacterial attacks as well. They also adversely affect the quality of sperm and cause precocious puberty in children. This study was performed to analyze seven preservatives used in pharmaceuticals and personal care products. Methods: Five kinds of pharmaceuticals and personal care products (PPCPs) were examined for analysis with a high performance liquid chromatography-diode array detector. Each sample was homogenized and the targeted compounds were extracted with methanol. The suspended particulate was removed by syringe filter. Next, the sample was injected into an HPLC system. The separation of the seven preservatives was achieved with a C18 column and gradient mode. The accuracies were between 73% and 120% and precision was lower than 11.58% (RSD). Results: All of the calibration curves showed good linearity with a coefficient of determination ($r^2$) over 0.999. Among the PPCP samples, the detection rate of preservatives was 32.5% for pharmaceuticals, 44.8% for toothpaste, 76.9% for mouthwash, 40.0% for body lotion and 56.0% for wet tissues. The average concentrations of the preservatives in PPCPs were BA 1141.0 mg/kg, MP 709.8 mg/kg, EP 624.9 mg/kg, PP 216.9 mg/kg, BP 167.8 mg/kg, and TCS 538.2 mg/kg. The most frequently detected preservatives in pharmaceuticals and personal care products were BA, MP and PP. The concentrations of preservatives exceeded Korean regulatory standards in 11 samples of medicines, three of mouthwash and two of body lotion. Conclusion: We found that most of the PPCP samples contained various preservatives. It is necessary to identify which preservatives were used and to determine the level of preservatives in PPCPs and to assess the health risk to susceptible populations such as children.