• Title, Summary, Keyword: Microbalance

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Measurement of Toluene Solubility in PVAc Using a Quartz Crystal Microbalance (PVAc에서 Quartz Crystal Microbalance를 이용한 톨루엔의 용해도 측정에 관한 연구)

  • Kim, S.B.
    • Elastomers and Composites
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    • v.43 no.3
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    • pp.166-172
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    • 2008
  • The resistance and frequency change of a quartz crystal microbalance during toluene absorption was measured for poly(vinyl acetate) (PVAc) with 268 nm thickness. Solubility of toluene in PVAc were measured at temperatures from 25$^{\circ}C$ to 42$^{\circ}C$ and pressures up to 28.4 torr. The frequency of a quartz crystal microbalance increased with increasing temperature and decreased with an increase in toluene vapor pressure. The resistance of a quartz crystal microbalance increased with increasing toluene vapor pressure and decreased with an increase in temperature. A greater pressure of toluene results in a greater solubility of the toluene into the PVAc film. The change of solubility was calculated by Sauerbrey equation.

Titanium Oxide Nanotube Arrays for Quartz Ctystal Microbalance (수정진동자 미세저울을 위한 티타늄산화물 나노튜브 어레이)

  • Mun, Kyu-Shik;Yang, Dae-Jin;Park, Hun;Choi, Won-Youl
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • pp.372-372
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    • 2007
  • Titanium oxide nanotube arrays were fabricated by the anodization of pure titanium thin film deposited at $500^{\circ}C$ on silicon substrates. The titania nanotubes were grown by anodization in nonaqueous-base electrolytes at different potentials between 5 V and 30 V. $TiO_2$ nanotube array with a small pore diameter of 40 nm and long titanium oxide layer of $4\;{\mu}m$ was obtained. The $TiO_2$ nanotube array was used as a porous electrode for quartz crystal microbalance (QCM). Nanoporous morphology of electrode will increase the sensitivity of microbalance.

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The Theory and Application or Piezoelectric Quartz Crystal Microbalance[PZ QCM] for Biosensor (압전 수정 결정 미량 천평[PZ QCM] 바이오센서의 원리와 응용)

  • 김의락
    • KSBB Journal
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    • v.18 no.2
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    • pp.79-89
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    • 2003
  • This article contains an overview of acoustic wave devices, the theory and application of piezoelectric quartz crystal microbalances(PZ QCM), clinical analysis, gas phase detection, DNA biosensors, drug analysis, food microbial analysis and environmental analysis.

Measurement of Water Absorption in Anticorrosive Organic Coatings Using Quartz Crystal Microbalance (QCM) (수정진동자 미세저울을 이용한 방식도막의 물 흡수 측정)

  • 이근대;도윤정;김진호;박성수;홍성수;서차수;박진환
    • Journal of Ocean Engineering and Technology
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    • v.17 no.6
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    • pp.77-82
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    • 2003
  • The absorption of water into an anti-corrosive organic coating, such as alkyd and urethane resin coating, was investigated, using a quartz crystal microbalance (QCM). Anticorrosive properties of the coatings were also measured, by means of electrochemical impedance spectroscopy (EIS). The overall absorption of water in the coating is determined by the chemical nature of resin, and decreases with increasing thickness. The enhancement of anti-corrosive performance, through increase of coating thickness, was more remarkable in the case of the coating that hadlower equilibrium water absorption. The absorption kinetics curves were Fickian in nature. The EIS analysis confirmed that the resin, having lower equilibrium water absorption, shows higher anti-corrosive performan.

Detection of human and bovine haptoglobin by using quartz crystal microbalance sensor chip containing secondary antibody (이차항체를 포함하는 수정미소저울 센서 칩을 이용한 사람과 소의 헵토글로빈 측정)

  • Kim, Sung-Il;Ha, In-Young;Choi, Suk-Jung
    • Journal of Sensor Science and Technology
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    • v.18 no.2
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    • pp.160-167
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    • 2009
  • In this study, secondary antibody-containing quartz crystal microbalance(QCM) sensor chip was prepared and utilized for the detection of human and bovine haptoglobin. Anti-goat immunoglobulin G antibody, which is a secondary antibody capable of capturing primary antibodies raised in goat, was immobilized through the reaction between hydrazide and aldehyde group prepared on the QCM surface and antibody respectively. The resulting sensor chip showed higher stability in the repeated surface regeneration with acidic dissociation solution as well as requiring lower amount of primary antibody when compared to the protein G sensor chip. The secondary antibody sensor chip was applied for the estimation of bovine and human haptoglobin.

Development of Quartz Crystal Microbalance-Based Immunosensor for the Determination of Low-Density Lipoprotein (Quartz Crystal Microbalance 시스템을 이용한 저밀도 지질단백질측정용 면역센서의 개발)

  • 김상현;윤현철;감학성
    • KSBB Journal
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    • v.13 no.4
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    • pp.337-342
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    • 1998
  • Immunosensor for the determination of LDL(Low-Density Lipoprotein), a good indicator for the diagnosis of atherosclerosis and hypercholesterolemia, was developed by using quartz crystal microbalance(QCM). The immunosensor consists of flow-through cell, oscillating circuit, oscilloscope, and frequency counter. FIA(Flow Injection Analysis) was applied to the QCM system for the measurement of LDL in liquid phase. Antibody showing binding affinity against LDL was immobilized on the gold electrode of a quartz crystal by covalent coupling via polyethylenimine / glutaredehyde. LDL was injected and bound to the antibody immobilized on the QCM immunosensor. The response of the immunosensor (F0 - F1) was found to be proportional to the LDL concentration from 200 $\mu\textrm{g}$/ml to 800 $\mu\textrm{g}$/ml. Operational conditions for the operation of immunosensor were also investigated in terms of sensitivity and non-specific binding.

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Immunoassay of haptoglobin and transferrin with proteinG-containing QCM sensor chip and unpurified antiserum (Protein G를 포함하는 수정미소저울 센서 칩과 정제되지 않은 항혈청을 이용한 헵토글로빈과 트랜스페린의 면역분석)

  • Ha, In-Young;Choi, Suk-Jung
    • Journal of Sensor Science and Technology
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    • v.17 no.5
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    • pp.380-386
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    • 2008
  • Quartz crystal microbalance immunosensor has a capacity to perform a label-free and real time detection of a trace amount of analyte through the specific interaction between antibody and antigen. However, immobilization of antibody molecules on the sensor surface is a troublesome procedure for researchers who are not experienced in chemistry. Protein G has a specific affinity to antibody and would serve as a capturing agent for antibody when immobilized on the sensor surface. In this work, we prepared a protein G sensor chip by immobilizing protein G on the surface of quartz crystal microbalance and examined its capability to detect human haptoglobin or human transferrin with unpurified corresponding antiserum. Specific and dose dependent response was observed when the protein G chip was used for detection of antigens after saturated with antiserum. We also verified several advantageous aspects of the protein G chip such as improved flexibility and sensitivity.

Quartz crystal Microbalance(QCM)-based Immunosensor for the Determination of LDL(Low-Density Lipoprotein)

  • Kim, Sang-Hyun;Yoon, Hyun-Chul;Kwak, Joo-Won;Kim, Hak-sung
    • Proceedings of the Korean Biophysical Society Conference
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    • pp.44-44
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    • 1996
  • Immunoserisor for the determination of LDL(Low-Density Lipoprotein) was developed by using quartz crystal microbalance(QCM) system. LDL is known to be a good indicator for the diagnosis of atherosclerosis and hypercholesterolemia. The immunosensor consists of four parts; detection cell, oscillating circuit, oscilloscope, and frequency counter, and this was interfaced with personal computer for signal processing. (omitted)

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Construction of Low Noise Electrochemical Quartz Crystal Microbalance

  • Hwang, Ui Jin;Im, Yeong Ran
    • Bulletin of the Korean Chemical Society
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    • v.17 no.1
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    • pp.39-42
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    • 1996
  • A new oscillator for electrochemical quartz crystal microbalance (EQCM) was developed by using an operational amplifier without any LC component. The home-made EQCM using this oscillator showed only 0.02 Hz frequency noise at 0.3 s gate time when a 6 MHz AT-cut crystal was used. Pb underpotential deposition on gold substrate in nitric acid media was examined to demonstrate the performance of this EQCM. The derivative of frequency change could be obtained without averaging multiple scans.

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