• Title, Summary, Keyword: Medication Adherence

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Influencing Factors on Medication Adherence in Colorectal Cancer Patients Receiving Oral Chemotherapy (대장암 환자의 경구용 항암제 복용이행과 영향요인)

  • Kim, Jeong-Hye
    • Asian Oncology Nursing
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    • v.12 no.3
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    • pp.213-220
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    • 2012
  • Purpose: The purpose of this study was to identify factors that influence medication adherence in colorectal cancer patients receiving oral chemotherapy. Methods: One hundred and nine colorectal cancer patients receiving oral chemotherapy were recruited in the cross-sectional survey design. A survey including medication adherence, knowledge about chemotherapy, self-efficacy, depression and symptom experience were completed. Results: The level of medication adherence was $7.38{\pm}.80$. Medication adherence showed significant differences according to perceived health status and combination of IV chemotherapy. Medication adherence was significant correlated with self-efficacy, depression and symptom experience. On stepwise regression analysis, the most important factors related to the medication adherence were symptom experience, perceived health status and combination of IV chemotherapy. These variables explained 17% of medication adherence. Conclusion: The level of medication adherence in colorectal cancer patients receiving oral chemotherapy was relatively high. It is important to develop nursing intervention for medication adherence in colorectal cancer patients that focus on symptom experience and to consider about perceived health status and combination of IV chemotherapy.

Impact of Cognitive Function and Self-efficacy on Medication Adherence of Elderly Patients with Chronic Disease (노인 만성질환자의 인지기능과 자기 효능감이 약물복용 이행도에 미치는 영향)

  • Ryu, Kyung-Hee;Son, Youn-Jung
    • Journal of Korean Biological Nursing Science
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    • v.15 no.3
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    • pp.107-114
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    • 2013
  • Purpose: This study was aimed to describe the level of medication adherence and to identify the impact of cognitive function and self-efficacy on medication adherence of elderly patients with chronic disease. Methods: The descriptive study included 303 patients over 65 years with chronic diseases from two medical centers in Cheonan city. Data were collected from July to November 2011. A questionnaire including questions on the Korean version of mini-mental state examination (MMSE-K), self-efficacy and medication adherence were completed by the subjects. Data were analyzed using the SPSS/WIN 20.0 program. Results: The mean score of medication adherence was $1.4{\pm}1.6$. In univariate analysis, exercise (t=2.85, p=.005), type of disease (F=3.91, p=.001) and self-efficacy (r=-.57, p<.001) were the significant factors related to medication adherence. Linear regression analysis demonstrated that self-efficacy (${\beta}$=-.57, p<.001) was a significantly associated factor with medication adherence. Self-efficacy explained about 33% of the total variance of the medication adherence in elderly patients. Conclusion: The results suggest that self-efficacy to medication can be a facilitator to medication adherence in elderly patients. However, these results indicate that there remains much work to be done in identifying other predictors of medication adherence of elderly patients with chronic diseases.

Medication Adherence of Elderly with Hypertension and/or Diabetes-mellitus and its' Influencing Factors (고혈압과 당뇨병 노인의 복약순응도와 이에 영향을 미치는 요인)

  • Kim, Seong-Ok
    • Korean Journal of Clinical Pharmacy
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    • v.21 no.2
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    • pp.81-89
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    • 2011
  • Medication adherence is an important public health issue. This study is conducted to explore non-adherence of elderly with hypertension and/or diabetes mellitus and to better understand its' influencing factors. To explore non-adherence, 605 elderly patients in community were surveyed with Modified Morisky Scale (MMS), from Aug 18 to Sept 19, 2008. MMS is designed to predict medication-taking behavior and outcomes, and also to explain persistence of the patient's long-term continuation of therapy, which is a significant factor in the long-term management of chronic diseases. Also, MMS is designed to classify patients into a high/low continuum for knowledge and motivation. Patients self reported medication adherence were average 4.66 with MMS (range 0-6), only 78% of patients hold high motivation of medication adherence although 95.5% of patients hold high knowledge of medication adherence. This study explores which factors influence to high motivation of medication adherence and it proved that patients' participation in work, education level, participation in private health insurance, number of medication and medication frequency per day, pharmacists' explanation, experience of non adherence due to cost are important factors to explain high motivation of medication adherence of elderly with hypertension and/or diabetes mellitus.

Perceptions of Anticoagulation Therapy and Medication Adherence among Patients taking Warfarin (와파린 복용 환자의 항응고요법에 대한 인식과 약물복용 이행)

  • Chu, Sang-Hui;Kang, Seok-Min;Kim, Do-Ree;Lee, Yoon-Ju
    • Journal of Korean Biological Nursing Science
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    • v.14 no.1
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    • pp.66-75
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    • 2012
  • Purpose: This study was conducted to measure medication adherence and perceptions of anticoagulation therapy and its relationship to patients taking warfarin. Methods: in a cross-sectional survey, 150 patients taking warfarin who had visited an outpatient clinic of a cardiovascular center in Seoul were included as research subjects. Medication adherence was measured using a visual analogue rating scale (VAS). Barriers and attitudes toward adherence, and oral anticoagulation knowledge, were measured using a structured questionnaire. Participants' medical records also were reviewed to identify clinical characteristics. Results: About one third of the participants (30.7%) reported medication adherence as 100%. The major barriers to adherence were identified as "Forgetting the time of medication" and "Not carrying their medication". Overall attitudes toward medication adherence were high, but oral anticoagulation therapy knowledge was low. To determine the relationship of medication adherence and perceptions of anticoagulation therapy, participants were stratified into three groups, based on their medication adherence levels (high adherence, moderate adherence, low adherence). Participants in the high adherent group more likely to be older (OR: 1.04, 95% CI: 1.005-1.071) and to have positive attitudes toward medication adherence (OR: 1.12, 95% CI:1.013-1.229) compared to the other two groups. Conclusion: The results show that age and attitude exerts significant influence on medication adherence in patients taking warfarin.

Review of Studies about Medication Adherence in Korea (약물이행과 관련된 국내 선행연구 고찰)

  • Yu, Seung Hee;Kang, JeongHee
    • Journal of Korean Public Health Nursing
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    • v.29 no.2
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    • pp.285-297
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    • 2015
  • Purpose: The purpose of this study was to analyze published studies on medication adherence in Korea. Methods: The studies were identified and data were collected from Oct. to Nov. 2014 through the RISS, KISS, NDSL, and Nanet websites. Key words including medication adherence and medication compliance were used. A total of 37 published studies were reviewed using criteria developed by researchers. Results: Studies published and associated with adherence have increased since 2010. Several instruments have be enused to date however, there is no critical standard regarding medication adherence. In addition, various interventions are available and have positive effects but the main concept is also deferent with adherence and compliance. Conclusion: There sults show that research related to adherence has actively increased. How ever there are various concepts, method sand standard. Therefore more studies are required in the future for development of a unified concept, methods and standards for adherence for future.

Factors Influencing Medication Adherence in Hemodialysis Patients: Focusing on Primary and Secondary Medical Care (혈액투석 환자의 약물복용 이행도 및 이행 영향요인: 1차, 2차 의료기관 중심)

  • Seo, Yon Hee;Lim, Sun Og;Hyeon, Eun Hee;Kim, Hae Won;Eom, Mi Ran
    • Perspectives in Nursing Science
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    • v.12 no.1
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    • pp.60-70
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    • 2015
  • Purpose: The purpose of this study was to identify the factors influencing medication adherence in hemodialysis patients among primary medical care and secondary medical care. Methods: A cross-sectional survey design was utilized. Data were collected using questionnaires from 280 hemodialysis patients who had taken prescribed medication regularly as a result of chronic renal failure at primary and secondary medical care in Korea. Data were analyzed using t-test, ANOVA, Pearson correlation coefficients, and multiple regression. Results: There were statistically significant differences in medication adherence according to living area (p=.002), health condition (p<.001), amount of medication (p=.004), inconvenience for taking medication (p<.001), and depression level (p=.001). The mean of medication adherence was 3.72 points. Medication adherence was explained by perceived barrier related to medication taking (${\beta}=.338$), attitude (${\beta}=.250$), and depression (${\beta}=.132$). Conclusion: This study strongly recommended that nursing intervention program to improve medication adherence should be developed and a match control study in improvement of medication adherence for hemodialysis patients needs to be done.

Genome-Wide Association Study of Medication Adherence in Chronic Diseases in the Korean Population

  • Seo, Incheol;Suh, Seong-Il;Suh, Min-Ho;Baek, Won-Ki
    • Genomics & Informatics
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    • v.12 no.3
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    • pp.121-126
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    • 2014
  • Medication adherence is generally defined as the extent of voluntary cooperation of a patient in taking medicine as prescribed. Adherence to long-term treatment with chronic disease is essential for reducing disease comorbidity and mortality. However, medication non-adherence in chronic disease averages 50%. This study was conducted a genome-wide association study to identify the genetic basis of medication adherence. A total of 235 medication non-adherents and 1,067 medication adherents with hypertension or diabetes were used from the Korean Association Resource project data according to the self-reported treatment status of each chronic disease, respectively. We identified four single nucleotide polymorphisms with suggestive genome-wide association. The most significant single nucleotide polymorphism was rs6978712 (chromosome 7, $p=4.87{\times}10^{-7}$), which is located proximal to the GCC1 gene, which was previously implicated in decision-making capability in drug abusers. Two suggestive single nucleotide polymorphisms were in strong linkage disequilibrium ($r^2$ > 0.8) with rs6978712. Thus, in the aspect of decision-making in adherence behavior, the association between medication adherence and three loci proximal to the GCC1 gene seems worthy of further research. However, to overcome a few limitations in this study, defining the standardized phenotype criteria for self-reported adherence should be performed before replicating association studies.

Construction of Explanatory Model for Medication Adherence in Older People with Chronic disease (만성질환을 가진 노인의 약물복용이행 설명모형 구축)

  • Min, Shin Hong;Kim, Jong Im
    • Journal of Korean Academy of Fundamentals of Nursing
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    • v.19 no.4
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    • pp.463-473
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    • 2012
  • Purpose: The main purpose of this study was to identify factors affecting medication adherence and to develop an explanatory model for medication adherence in elders with chronic disease. Method: Empirical data were collected from 312 older adults with chronic disease and the data collect period was from August 8 to 31, 2011, and were analyzed using SPSS for Windows 19.0 program and confirmatory factor analysis with the structural equation model (SEM) procedure performed with AMOS 19.0 program. Results: Results of this study showed that perceived self-efficacy was the strongest factor influencing medication adherence, and it affected also outcome expectations positively but impediments were negatively influenced by self-efficacy. Outcome expectations and impediments subsequently acted on medication adherence with the same relationship as self-efficacy. In additional results, self-efficacy and medication adherence were further significantly affected by the factors; social support, medication knowledge, and depression. Conclusion: These results show that nursing interventions to promote medication adherence in this population should focus on self-efficacy promotion including social support, education for delivery of medication knowledge, and reduction in depression.

Antihypertensive Drug Medication Adherence of People with Disabilities and its Affecting Factors in Korea (고혈압약 투약을 시작한 장애인의 투약 순응도와 이에 영향을 미치는 요인)

  • Park, Jong-Hyock;Shin, Young-Soo;Lee, Sang-Yi;Park, Jae-Hyun
    • Journal of Preventive Medicine and Public Health
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    • v.40 no.3
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    • pp.249-258
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    • 2007
  • Objectives : The aims of this study were to estimate the antihypertensive medication adherence in people with a disability and a history of taking antihypertensive medication, and to identify the factors affecting medication adherence. Methods : The National Health Insurance claims data were linked with the National Disability Registry. People with a disability, who received a prescription of antihypertensives, were identified from a total of 85,098 cases. Cumulative medication adherence (CMA) was used as an indicator of medication adherence. A CMA > 80% was defined as appropriate medication adherence. Multiple logistic regression analysis was used to identify the factors affecting medication adherence. Results : The average CMA in a total of 85,098 patients was 79.5%. The appropriate adherence $(CMA{\geq}80%)$ rate was 54.5% and 20.5% of patients had a CMA < 50%. Multiple logistic regression analysis revealed that the probability of appropriate adherence decreased with decreasing number of prescription days per visit, increasing number of providers, the patients' residential area moving from urban to rural areas, and when patients have an internal organ disability, auditory impairment, mobility impairment. Conclusions : The adherence to antihypertensive medication in people with a disability is influenced by various socio-economic, clinical and regional factors. In particular, the disabled who have locomotive and communication disabilities and internal organ impairments have a higher probability of under-adherence to antihypertensive medication adherence in Korea.

Effects of Health Literacy, Self-efficacy, and Social Support on Medication Adherence in the Elderly (노인의 건강정보이해력, 자기효능감, 사회적 지지가 약물복용이행에 미치는 영향)

  • Park, Youngrye;Jang, Eun Hee;Kim, Sun Hwa;Park, So Hee;Oh, Hee Sook
    • Journal of muscle and joint health
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    • v.25 no.1
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    • pp.30-38
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    • 2018
  • Purpose: The purposes of this study were to examine the relationships between health literacy, self-efficacy, social support, and medication adherence and to determine its impact on medication adherence in the elderly. Methods: This study was a descriptive research study. Structured questionnaires were used for survey with a convenience sample of 220 elderly in a community. Data were analyzed using descriptive statistics, ANOVA, Pearson's correlation coefficient, and stepwise multiple regression with IBM SPSS 18.0. Results: The mean scores of health literacy, self-efficacy, social support, and medication adherence were $35.89{\pm}19.39$, $55.34{\pm}7.44$, $86.54{\pm}15.90$ and $4.82{\pm}1.83$, respectively. There were significant correlations between health literacy, self-efficacy, social support, and medication adherence. Social support (${\beta}=.23$, p=.001) and health literacy (${\beta}=.21$, p=.002) were significantly associated factors with medication adherence. Conclusion: This finding showed that nursing interventions to promote medication adherence in the elderly group should focus on social support program and health literacy intervention.