Ductiluty factor has played an important role in seismic design as it is key component of response modification factor(R). In this stuty, ductility factors() are calculated by multiplying ductility factor for SDOF systems() and MDOF modification factors(). Ductility factors() for SDOF systems are computed from nonlinear dynamic analysis undergoing different level of displacement ductiluty demands and period when subjected to a large number of recorded earthquake ground motions. The MDOF modification factors() are proposed to account for the MDOF systems, based on previous studies. A total of 108 prototype steel frames are designed to investigate the ductility factors considering the number of stories(4, 8 and 16-stories), framing system(Perimeter Frames, PF and Distributed Frames, DF), failure mechanism(Strong-Column Weak-Beam, SCWB and Weak-Column Strong-Beam, WCSB), soil profiles(SA, SC and SE in UBC 1997) and seismic zone factors(Z=0.075, 0.2 and 0.4 in UBC 1997). It is shown that the number of stories, failure mechanisms (SCWB, WCSB), and soil profiles have great influence on the ductility factors, however, the structural system(Perimeter frames, Distributed frames), and seismic zones have no influence on the ductility factors.