• Title, Summary, Keyword: MCP-1

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Effect of 1-Methylcyclopropene(1-MCP) on the Postharvest Life and Fruit Quality of Cucumber (1-Methylcyclopropene(1-MCP) 처리가 오이의 신선도 유지에 미치는 영향)

  • Yang, Yong-Joon
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.9 no.6
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    • pp.1882-1888
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    • 2008
  • Effects of 1-MCP(1-methylcyclopropene) on the postharvest life and fruit quality of cucumber 'Baekdadaki' were investigated. Cucumber were held at room and cold chamber($10^{\circ}C$) treated with several concentrations of 1-MCP. Physico-chemical characteristics such as fresh weight and firmness were greatly varied during storage, and the treatment with I-MCP(500ppb) showed the minimal loss of the values at harvest. The peel b value representing a senescence process was higher investigated in 1-MCP(250 and 1,000ppb treatment, and led to the apparent yellowing and softening after cold storage for 15 days. 1-MCP(500ppb) showed lower decay rate and better marketability of cucumber than other treatments after cold storage for 15 days. The respiration rate was higher found in cucumber treated with 1-MCP(250ppb) than in other treatment. Ethylene evolution was most detected in cucumber treated with 1-MCP(1000ppb) after room storage for 6 days. 1-MCP did not affect the production of ethylene in cucumber during room and cold storage.

Extending the Vase Life of Cut Iris 'Blue Magic' Flowers by 1-Methylcyclopropene (1-Methylcyclopropene 처리에 의한 아이리스 '블루매직'의 절화수명 연장)

  • Kim, Young-A;Lee, Jong-Suk;Park, Jong-Su;Lee, Poong-Ok
    • Horticultural Science & Technology
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    • v.28 no.6
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    • pp.985-989
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    • 2010
  • This experiment was conducted to clarify the effects of 1-methylcyclopropene (1-MCP) on vase life of cut 'Blue Magic' iris. Pretreatment for 4 h with concentrations of 500 nL and 1000 nL 1-MCP, an inhibitor of ethylene action, inhibited the wilting and inrolling response of cut iris. The vase life of iris flowers of 500 nL or 1000 nL 1-MCP treatment was prolonged to 0.5 day compared to those held in distilled water (control). Vase life of iris showed no significant difference between $3{\mu}L{\cdot}L^{-1}$ ethylene exposure after 1-MCP treatment and control. 1-MCP treatment inhibited inrolling and increased fresh weight, water uptake, and water balance. The increase of fresh weight was high in 500 nL 1-MCP treatment and water uptake was increased by 1000 nL 1-MCP. Especially, iris flower without 1-MCP treatment dramatically decreased the water uptake as compared to the control for four or five days. Water balance of iris flowers held in water was changed to minus value faster than those with pretreatment of 1-MCP.

Comparison of the Change in Quality and Ethylene Production between Apple and Peach Fruits Treated with 1-Methylcyclopropene (1-MCP) (1-Methylcyclopropene (1-MCP) 처리에 따른 사과와 복숭아 과실의 품질 및 에틸렌 생성 변화의 비교)

  • Choi Seong-Jin
    • Korean Journal of Food Preservation
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    • v.12 no.6
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    • pp.511-515
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    • 2005
  • The responses of 'Tsugaru' apple and 'Baekhyang' peach fruits treated with 1-MCP, the ethylene inhibitor, were compared. In Tsugaru apple fruits, the reduction of flesh firmness and titratable acidity were significantly retarded for 2 weeks by the treating fruits with 1 or 5 ppm of 1-MCP immediately after harvest The respiration decreased continually for 2 weeks and the onset of ethylene production were also retarded severely. However, in Baekhyang peach fruits, the effects of 1-MCP treatment on the respiration and ethylene production were only transient and the firmness reduction was retarded slightly by the repeated 1-MCP treatments. The responsiveness of the Baekhyang peach fruits on ethylene seems to be recovered rapidly after 1-MCP treatment. In case of Baekhyang fruits, the 1-MCP should be treated repeatedly for effective ethylene inhibition, and the ethylene accumulation should be avoided during the 1-MCP treatment.

Association of MCP-1 polymorphism with cardiovascular disease risk factors in Korean elderly (한국인의 MCP-1 유전자 다형성과 유전형에 따른 심혈관계질환 위험인자와의 연관성)

  • Park, Hee Jung
    • Journal of Nutrition and Health
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    • v.46 no.6
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    • pp.511-520
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    • 2013
  • Monocyte chemoattractant protein-1 (MCP-1) plays an important role in cardiovascular disease (CVD). Genetic polymorphism in the regulatory regions of MCP-1 could affect MCP-1 expression. The purpose of the study was to explore the possible association of MCP-1 -2518 A/G genetic polymorphism and CVD risk factors in the elderly Korean population. Dietary, anthropometric, and biochemical factors were assessed in 168 subjects. The frequency of A/A, G/A, and G/G genotypes was 14.2%, 45.8%, and 40.0%, respectively. The blood level of MCP-1 was significantly higher in subjects with A/A genotype. The MCP-1 level was significantly higher in A/A genotype with hypercholesterolemia than in other genotypes. Meat intake and percent energy from lipids were significantly positively correlated with the MCP-1 level, especially, stronger in A/A genotype. In the stepwise discriminant analysis, TNF-${\alpha}$ level, meat intake, HDL-C were associated with MCP-1 in all subjects (model $R^2=24%$). TNF-${\alpha}$ level, sugar intake, cholesterol intake, and meat intake affected MCP-1 in A/A genotype (model $R^2=82%$), but not in G/A or G/G. In conclusion, subjects possessing A/A genotype exhibited higher levels of MCP-1 than other genotypes in Korean elders. Further, meat, sugar, and cholesterol intakes affected the MCP-1 level. Therefore, the decrement of meat, sugar, and cholesterol intakes helps to normalize the MCP-1 level and can decrease CVD risk in A/A genotype.

Development of the Phage Displayed Peptide as an Inhibitor of MCP-1 (Monocyte Chemoattractant Protein-1)-mediated Angiogenesis

  • Jeong, Sun-Joo
    • Proceedings of the Microbiological Society of Korea Conference
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    • pp.132-134
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    • 2005
  • The CC chemokine, monocyte chemoattractant protein-1 (MCP-1), plays a crucial role in the initiation of atherosclerosis and has direct effects that promote angiogenesis. To develop a specific inhibitor for MCP-1-induced angiogenesis, we performed in vitro selection employing phage display random peptide libraries. Most of the selected peptides were found to be homologous to the second extracellular loops of CCR2 and CCR3. We synthesized the peptide encoding the homologous sequences of the receptors and tested its effect on the MCP-1 induced angiogenesis. Surface Plasmon Resonance measurements demonstrated specific binding of the peptide to MCP-1 but not to the other homologous protein, MCP-3. Flow cytometry revealed that the peptide inhibited the MCP-1 binding to THP-1 monocytes. Moreover, CAM and rat aortic ring assays showed that the peptide inhibited MCP-1 induced angiogenesis. Our observations indicate that the MCP-1-binding peptide exerts its anti-angiogenic effect by interfering with the interaction between MCP-1 and its receptor.

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Age-Associated Increasing of MCP-1 in Adults

  • Im, Jee-Aee;Kim, Sang-Hwan
    • Biomedical Science Letters
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    • v.13 no.3
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    • pp.183-187
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    • 2007
  • Monocyte chemoattractant protein-1 (MCP-1) and interleukin-8 (IL-8) playa key role in development of atherosclerosis. To take into account the atherogenic properties of MCP-1 and IL-8 and its influence on insulin resistance, we examined circulating levels of MCP-1 and IL-8 in adults. We recruited 292 subjects (84 males and 208 females) aged between 29 and 79 years. MCP-1 and IL-8 levels were measured by enzyme-linked immunosorbent assay. Age, total cholesterol, HDL-cholesterol, and LDL-cholesterol levels were significantly higher in female subjects (P<0.01, respectively), but diastolic blood pressure (BP) was significantly lower in female subjects compared to male subjects. MCP-1 and IL-8 levels were tended to increase with age, the highest in their seventies. MCP-1 (P=0.05) and IL-8 (P<0.01) levels were higher in males than in females. MCP-1 was positively correlated with age (r=0.17, P<0.05), IL-8 (r=0.26, P<0.01), fasting insulin (r=0.30, P<0.01), and HOMA-IR (r=0.29, P<0.01). In linear regression analysis, age was found to be independent factor associated with MCP-1 adjusted by age, BMI, fasting glucose, triglyceride, and systolic BP. In conclusion, age was found to be independent factor associated with MCP-1. It is possible that an increase of MCP-1 in adults with age may be risk to atherosclerosis and diabetic properties.

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Sorption Behavior of 1-Methylcyclopropene on Adsorbing Agents for Use in Extending the Freshness of Postharvest Food Products

  • Lee, Youn-Suk;Shin, Han-Seung
    • Food Science and Biotechnology
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    • v.15 no.4
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    • pp.572-577
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    • 2006
  • The physiochemical interactions of 1-methylcyclopropene (1-MCP) and adsorbing agents can be described using a very powerful tool, inverse gas chromatography (IGC). Sorption behavior of 1-MCP on various adsorbing agents was assessed using the profile peaks of 1-MCP at an infinite dilution concentration using the IGC technique. Chromatogram peaks of 1-MCP adsorption were not observed for the adsorbing agent activated carbon. The forms of sorption isotherms followed Henry's law, and behaved according to the binding site theory. Specific retention volume and distribution coefficients for 1-MCP on the adsorbing agents were determined at 50, 60, 70, and $80^{\circ}C$, respectively. Silica gel had a much higher number of binding sites for 1-MCP compared to Tenax-TA and activated clay agents. Meanwhile, activated carbon proved to be a very strong binding agent for 1-MCP based on 1-MCP efficiency experiments on the selected adsorbing agents. However, as a proper means of delivering 1-MCP molecules to fresh food products, activated carbon is not fit for the binding and release of 1-MCP gas under dry or high humidity conditions because activated carbon has a strong affinity for 1-MCP, even when treated with distilled water.

Effects of 1-MCP and AVG on the Vase Life of Cut Cymbidium Flowers (1-MCP, AVG 처리가 절화 심비디움의 수명에 미치는 효과)

  • Lee, Young-Ran;Choi, Seong-Youl;Kwon, Oh-Keun;Huh, Yeun-Joo
    • FLOWER RESEARCH JOURNAL
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    • v.18 no.4
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    • pp.251-255
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    • 2010
  • This study was conducted to investigate the detrimental effects of decapping and emasculation on the postharvest quality and the vase life of cut Cymbidium flowers with or without 1-Methylcyclopropene (1-MCP) and Aminoethoxyvinylglycine (AVG) treatments. The vase life treated by 1-MCP 150 ppb for four hours regardless of decapping or emasculation was significantly prolonged 12 days more. Ethylene production in the treatment without 1-MCP began to be raised from 7days, 1-MCP treatments, regardless of the concentration of processing did not occur until 15days. Ethylene began to production when the lip began to coloration. Compared to the 1-MCP effect, the AVG treatment of 0.5 and 1mM for four hours prolonged the vase life about nine days more. Whereas, the only decapping or emasculation treatments were effective to more three days longer in the vase life of cut Cymbidium' Halleluiah' flowers. 1-MCP treatment was very beneficial for Cymbidium 'Halleluiah' cut flowers than AVG.

Effect of 1-Methylcyclopropene (1-MCP) Treatment on the Quality Characteristics and Pigmentation of Tomato Fruit (Lycopersicon Esculentum Mill.) (1-Methylcyclopropane 처리가 토마토 선도유지 효과 및 색소 변화에 미치는 영향)

  • Lee, Youn-Suk;Chung, Dae-Sung;Harte, Bruce R.;Shin, Joong-Min
    • Horticultural Science & Technology
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    • v.28 no.4
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    • pp.600-608
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    • 2010
  • The quality attributes of tomato fruit ($Lycopersicon$ $Esculentum$ Mill.) to treatments with 1-methylcyclopropene (1-MCP) were studied. Harvested tomato fruit was treated one time at the initiation of storage or once-a-day during storage with $1{\mu}L/L$ 1-MCP at different storage temperatures, 12, 17, and $23^{\circ}C$. The results showed that both lower temperature and duration of 1-MCP treatment played an important role in ripening of tomato fruit. The once-a-day 1-MCP treatment was presented to be very effective in delaying quality changes of tomato fruit. The amount of chlorophyll and lycopene were measured to assess the impact of 1-MCP and temperature treatments on ripening, using a specific extinction coefficient absorbance technique. Storing tomato fruit at $12^{\circ}C$ resulted in a longer ripening period (color change) than tomato fruit stored at $17^{\circ}C$ and $23^{\circ}C$. 1-MCP treatment was very effective in retarding chlorophyll degradation and lycopene formation in the pericarp tissue of the tomato fruit at the different storage temperatures. The 1-MCP treatments affected the total chlorophyll content in different fruit tissues of the pericarp and placenta. Exposure of tomato fruit to 1-MCP gas at $12^{\circ}C$, using the once-a-day treatment, was highly effective in delaying pigment and color change.

Response of Early-season Asian Pear 'Hanareum' Treated with GA4+7 to Postharvest Application of 1-methylcyclopropene (1-MCP) (조생종 배 '한아름'에 대한 GA4+7 및 1-methylcyclopropene(1-MCP) 처리 반응)

  • Lee, Ug-Yong;Oh, Kwang-Suk;Lim, Byung-Sun;Wang, Mao-Hua;Hwang, Yong-Soo;Chun, Jong-Pil
    • Horticultural Science & Technology
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    • v.32 no.5
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    • pp.645-654
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    • 2014
  • This study was conducted to investigate the effect of 1-methylcyclopropene (1-MCP, $1.0{\mu}L{\cdot}L^{-1}$), a known ethylene action inhibitor, on fruit quality and incidence of physiological disorders during a simulated marketing period at $25^{\circ}C$ for 20 days in early-season Asian pear (Pyrus pyrifolia Nakai) 'Hanareum' that had been treated with 0, 0.5, 1.2 or 2.4% $GA_{4+7}$. Weight loss of stored fruits increased with $GA_{4+7}$ concentration, and the 1-MCP treatment slightly reduced the weight loss rates during the marketing period. Flesh firmness decreased abruptly in all 1-MCP-untreated fruits as the storage period extended to 10 d, whereas the firmness of 1-MCP-treated fruits remained high (> 30 N) during 15 days shelf-life. The effect of 1-MCP was significantly reduced when fruits were subjected to increased GA concentration. Higher soluble solids content and acidity during extended shelf-life were also apparent in 1-MCP-treated 'Hanareum' pears. The L-values (lightness) and hue angles of 1-MCP treated samples were higher than those of controls during 20 days shelf-life, but the a-value (redness) was lower in 1-MCP treated fruits. 1-MCP treatment did not decrease the level of ethylene evolution regardless of $GA_{4+7}$ concentration during shelf-life in early-season Asian pear 'Hanareum'. By contrast, 1-MCP treatment decreased the respiration rate significantly during shelf-life. The efficacy of 1-MCP was greatest in the GA-untreated fruit and was reduced as the $GA_{4+7}$ concentration increased. 1-MCP treatment influenced the severity of physiological disorders including core browning and mealiness: 1-MCP treatment completely blocked the incidence of core browning of during 15 days shelf-life, and reduced the severity of mealiness during 20 days shelf-life regardless of $GA_{4+7}$ concentration. Based on our results, we conclude that the use of $1{\mu}L{\cdot}L^{-1}$ 1-MCP can be of great benefit for maintaining quality and preventing physiological disorders in early-season pear cultivar 'Hanareum' pear, whereas its efficacy decreases with the concentration of $GA_{4+7}$ whereas its efficacy gradually decreases when the concentration of $GA_{4+7}$ paste increased.