• Title, Summary, Keyword: Integrity

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Effect of Microsurgical Varicocelectomy on Human Sperm Nucleus DNA Integrity (미세술기를 이용한 정계정맥류절제술이 정자 핵 내 DNA Integrity에 미치는 효과)

  • Kim, Gi-Young;Lee, Jae-Seok;Chi, Hee-Jun;Kim, Jong-Hyun
    • Clinical and Experimental Reproductive Medicine
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    • v.37 no.3
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    • pp.245-251
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    • 2010
  • Objective: Human sperm nucleus DNA damage may negatively affect pregnancy outcome, and the spermatozoa of infertile men have more DNA damage than that of fertile men. The aim of this study was to evaluate the effect of microsurgical varicocelectomy on human sperm nucleus DNA integrity. Methods: We reviewed the medical records of 18 subfertile male patients who underwent microsurgical varicocelectomy at our hospital from April 2006 to April 2007. Varicocele was diagnosed by physical examination and Doppler ultrasound. Standard semen analysis was performed in 18 patients before and 4 months after microsurgical varicoceletcomy using a computer assisted semen analyzer. Sperm nucleus DNA integrity was assessed by a single-cell gel electrophoresis (comet assay). Results: No recurrence of varicocele was observed after 4 months later. The DNA fragmentation index improved after varicocelectomy compared with pre-operatively (19.3 versus 13.7%, respectively, p<0.05). Semen analysis parameters (total count, concentration, motile sperm, viability, strict morphology) increased after varicocelectomy, but the difference did not reach statistical significance. Conclusion: Our data suggest that microsurgical varicocelectomy can improve semen analysis parameters and human sperm nucleus DNA integrity in infertile men with varicocele.

A Rule-Based Database Verification System Based on the Integrity Constranints (무결성 제약에 기초한 규칙 기반 데이타베이스 검증 시스템)

  • Ryu, Myeong-Chun;Park, Chang-Hyeon
    • The Transactions of the Korea Information Processing Society
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    • v.3 no.1
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    • pp.77-86
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    • 1996
  • In managing a certain database, the integrity of data is very important. The important. The integrity constrains thus should be considered carefully when a database is designed and, after the database is created, it is required for a database manager to check continuously if some data contained in the database violate the integrity constraints considered. It is however not easy to check the violateion of integrity constraints when the size and the complexity of database are increased. This paper suggests a rule-based database verification system to relax the difficulty of checking the integrity violation, in which a database is coupled with a rule-based system including the knowledge about the integrity constraints. The rule-database verification system suggested accepts the model descriptions of an application domain, generates the knowledge base consisting of rules and facts by analyzing the model description and proceeds the verification process to check the integrity of the database.

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A Mobile OS Integrity Verification Using Bootloader & Physically Independent Storage Device (부트로더와 물리적으로 독립된 저장장치를 이용한 모바일 운영체제 무결성 검증)

  • Park, Jae-Kyung;Lee, Sang-Hun;Kwon, Mi-Young;Kim, Hyo-Nam
    • Journal of the Korea Society of Computer and Information
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    • v.19 no.12
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    • pp.123-132
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    • 2014
  • In this paper, we study the verification techniques for OS integrity that can be more fatal than applications in case of security issues. The dissemination of smartphones is rapidly progressing and there are many similarities of smartphones and PCs in terms of security risks. Recently, in mobile network environment, there is a trend of increasing damages and now, there are active researches on a system that can comprehensively respond to this. As a way to prevent these risks, integrity checking method on operation system is being researched. As most integrity checking algorithms are classified by verification from the levels before booting the OS and at the time of passing on the control to the OS, in which, there are minor differences in the definitions of integrity checking or its methods. In this paper, we suggests the integrity verification technique of OS using a boot loader and a physically independent storing device in the mobile device.

Effects of Storage in Different Commercial Semen Extenders on Sperm Motility, Viability and Membrane Integrity of Korean Native Boar Spermatozoa

  • Sa, Soo-Jin;Kim, In-Cheul;Choi, Sun-Ho;Hong, Joon-Ki;Kim, Du-Wan;Cho, Kyu-Ho;Kim, Young-Hwa;Chung, Ki-Hwa;Park, Jun-Cheol
    • Journal of Embryo Transfer
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    • v.28 no.4
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    • pp.349-353
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    • 2013
  • The objective of this study was to compare the effect of semen extenders on the sperm motility, viability, acrosome integrity and functional integrity of plasma membrane (HOST: hypo-osmotic swelling test) during liquid preservation of Korean Native boar semen. In this experiment, semen was diluted in Androhep plus, Beltsville Thawing Solution (BTS), ModenaTM, Seminark and Vitasem LD. Sperm-rich fractions were collected from three Korean Native boars and sub-samples were diluted ($30{\times}10^6$ spermatozoa/ml) in different semen extenders. Semen samples were stored at $17^{\circ}C$ for 96 hours. On everyday (0, 24, 48, 72, 96 h) after storage, the sperm characteristics relevant for fertility, such as sperm motility, viability, acrosome integrity and HOST positive were evaluated. The motility of spermatozoa stored in different extenders was no significantly different among other extenders (P>0.05). Also, no difference was observed among samples processed with different extenders in the percentage of sperm viability, acrosome integrity and HOST positive. All extenders maintained a high percentage (70%) of sperm motility, viability and acrosome integrity through 96 h of storage. The result of this study show that there was no significant differences among extenders in their capacity to preserve motility, viability and membrane integrity of spermatozoa from normal, fertile Korean Native boars for 96 h of liquid preservation at $17^{\circ}C$.

A Representation of Engineering Change Objects and Their Integrity Constraints Using an Active Object-Oriented Database Model (능동형 객체지향적 데이터베이스 모텔을 이용한 설계변경 개체 및 제약조건의 표현)

  • 도남철
    • Journal of Information Technology Applications and Management
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    • v.10 no.1
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    • pp.111-125
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    • 2003
  • This paper proposes a product data model that can express and enforce integrity constraints on product structure during engineering changes (ECs). The model adopts and extends an active object-oriented database model in order to Integrate IC data and their integrity constraints. Tightly integrated with product structure, It will enable designers to maintain and exchange consistent EC data throughout the product life cycle. In order to properly support operations for ECs, the model provides the data, operations, and Event-Condition-Action rules for nested ECs and simultaneous EC applications to multiple options. in addition, the EC objects proposed In the model integrate the data and Integrity constraints into a unified repository. This repository enables designers to access all EC data and integrity constraints through the product structure and relationships between EC objects. This paper also describes a prototype product data management system based on the proposed model In order to demonstrate its effectiveness.

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A Study on FAD Development for Probabilistic Pressure Tube Integrity Assessment (압력관의 확률론적평가에 타당한 파손평가선도 작성에 관한 연구)

  • Kwak, Sang-Log;Wang, Jong-Bae;Choi, Young-Hwan;Park, Youn-Won
    • Proceedings of the KSME Conference
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    • pp.1211-1215
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    • 2003
  • Pressure tubes are major component of nuclear reactor, but only selected samples are periodically examined due to numerous numbers of tubes. Current in-service inspection result show there is high probability of flaw existence at un-inspected pressure tube. Probabilistic analysis is applied in this study for the integrity assessment of un-inspected pressure tube. But all the current integrity evaluations procedures are based on conventional deterministic approaches. So many integrity evaluation parameters are not directly apply to probabilistic analysis. As a result of this study failure assessment diagram are proposed based on test data.

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MiSA (Method of Integrated Spectral Analysis) to Evaluate Structural Integrity of Tunnel Concrete Lining (터널 콘크리트 라이닝의 구조적 특성평가를 위한 탄성파 기법, MiSA의 개발)

  • 김기봉;추진호;조성호;조미라
    • Proceedings of the Korean Geotechical Society Conference
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    • pp.49-56
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    • 2001
  • The techniques to make assessment of the structural integrity of underground structures include Infrared thermagraphy, GPR using the reflection of the electromagnetic wave, ultrasonic test, seismic methods using the propagation of elastic wave, and etc These methods have pros and cons in the assessment of the structural integrity in the complex environment of the underground structure, so that a single method alone is not enough to evaluate parameters required for the assessment. In this study, a new seismic method was proposed to improve the existing methods and to provide an additional information like stiffness of concrete. The proposed method combines the advantages of the modified impact-echo test and the SASW method. To verify the validity of the proposed method, a large scale model of a tunnel concrete liner was built and the proposed method was applied to the center of the model and also to the corner of the model which has several distinct reflection boundaries.

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Structural Integrity Evaluation of Fuel Test Loop Submerged in Water Subjected to Postulated Pipe Rupture

  • Lee, Choon-Yeol;Kwon, Jae-Do;Lee, Yong-Son;Kim, Kil-Soo;Kim, Jun-Yeun
    • Journal of Mechanical Science and Technology
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    • v.14 no.2
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    • pp.215-225
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    • 2000
  • The structural integrity of the fuel test loop (FTL) in a Korean experimental reactor is evaluated when the FTL, submerged in a water environment, is subjected to a postulated pipe rupture. The analyses are performed under static and dynamic conditions, imposing the thrust force history at each postulated pipe rupture section. Through analysis the following results are found: l) A double ended guillotine can not be expected based on the toughness of the material, 2) the structural integrity of the chimney surrounding the FTL would not impede the structural integrity by the pipe whip. All analyses are performed by finite element methods.

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Building A PDM/CE Environment and Validating Integrity Using STEP (STEP을 이용한 PDM/CE환경의 구축과 데이타 무결성 확인)

  • 유상봉;서효원;고굉욱
    • The Journal of Society for e-Business Studies
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    • v.1 no.1
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    • pp.173-194
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    • 1996
  • In order to adapt today's short product life cycle and rapid technology changes., integrated systems should be extended to support PDM (Product Data Management) or CE(Concurrent Engineering). A PDM/CE environment has been developed and a prototype is Presented in this paper. Features of the PDM/CE environment are 1) integrated product information model (IPIM) includes both data model and integrity constraints, 2) database systems are organized hierarchically so that working data C8Mot be referenced by other application systems until they are released into the global database, and 3) integrity constraints written in EXPRESS are validated both in the local databases and the global database. By keeping the integrity of the product data, undesirable propagation of illegal data to other application system can be prevented. For efficient validation, the constraints are distributed into the local and the global schemata. Separate triggering mechanisms are devised using the dependency of constraints to three different data operations, i.e., insertion, deletion, and update.

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Evaluation of Structural Integrity of Three-axle Bogie Frame used in Railway Freight Cars (평판화차에 사용되는 3축 대차의 구조 안전성 평가)

  • Kang, Seung-Gu;Shin, Kwang-Bok;Im, Jae-Moon;Park, Jung-Joon;Jeon, Seung-Gie
    • Journal of The Korean Society of Manufacturing Technology Engineers
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    • v.26 no.4
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    • pp.436-440
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    • 2017
  • This study evaluated the design and structural integrity of a three-axle bogie frame in a railway freight car through a numerical analysis and an experimental evaluation. A three-axle bogie frame, which supports the weight of the car body and load, is required to transport heavier cargo because two-axle vehicles have structural limitations. Therefore, this study performed a structural analysis and static load tests to evaluate the design and structural integrity of a three-axle bogie frame. The results obtained from the numerical analysis were compared to those of the experiments. For the bogie frame used in the experiments, a failure evaluation was performed using non-destructive methods. The numerical analysis and experimental evaluation were satisfactory for the structural integrity evaluation.