• Title, Summary, Keyword: Human papilloma virus(HPV)

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Convergence Study of Knowledge, Health Beliefs and HPV Preventive Behavior Intention about Human Papilloma Virus(HPV) Vaccination among Health College Students (일부 보건계열 대학생의 인유두종 바이러스 지식과 예방접종 관련 건강신념 및 감염 예방행위의도에 관한 융복합 연구)

  • Jang, Young-Mi;Han, Jin-Sook;Moon, Young-Sook
    • Journal of Digital Convergence
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    • v.13 no.9
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    • pp.313-321
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    • 2015
  • The purpose of this study was to identify the knowledge level, health beliefs related to HPV vaccination and HPV preventive behavior intention of human papilloma virus among health college student in Korea. A quantitative, descriptive design was used to study 264 students in D-city, M-city recruited from June 1 to June 15, 2014. The data were analyzed SPSS 21.0 program. The average level of HPV knowledge, health beliefs related to HPV vaccination and HPV preventive behavior intention about human papilloma virus were relatively low. No correlation between HPV knowledge and health beliefs. But health beliefs related to HPV vaccination have risen even higher degree of infection prevention behaviors. Therefore, it is necessary for specific methods, such as education programs, including HPV knowledge to improve future health beliefs related to HPV vaccination and HPV preventive behavior intention of human papilloma virus.

Immunohistochemical study on the expression of matrix metalloproteinase 2 and high-risk human papilloma virus in the malignant progression of papillomas

  • Lee, Ho-Jin;Kim, Jin-Wook
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.39 no.5
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    • pp.224-230
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    • 2013
  • Objectives: Papilloma frequently develops as a benign tumor of the head and neck area, but its potential for malignant transformation has yet to be studied. This study aims to provide basic information for papillomas using the immunohistochemical staining of matrix metalloproteinase 2 (MMP-2) and human papilloma virus (HPV) 16 and 18. Materials and Methods: To evaluate the malignant transformation of papillomas, the selected tissue samples were serially diagnosed with pre-cancerous papilloma (with epithelial dysplasia, pseudo-epitheliomatous hyperplasia) or malignant lesion (squamous cell carcinoma, SCC) after the first diagnosis (squamous papilloma, inverted papilloma). The selected tissues were stained with an antibody to MMP-2 and HPV 16-E7, HPV 18-L1. A statistical analysis was performed according to each transformation step. Results: The epithelial layer of papilloma and pre-cancerous papilloma lesions had a similar MMP-2 expression, but that of the malignant lesion had a significantly increased MMP-2 expression. HPV 16 and 18 infection rates were 28.6%, 33.3% and 63.6% in papillomas, pre-cancerous papilloma lesions, and SCC. Conclusions: A relatively high MMP-2 expression and HPV 16 or 18 infection of papillomas may be associated with early events in the multistep processes of malignant transformation of papillomas.

Prevalence and Type Distribution of Human Papillomavirus Infection Using the INNo-Lipa Assay, Kerman, Southeast Iran

  • Afshar, Reza Malekpour;Mollaie, Hamid Reza;Fazlalipour, Mehdi;Arabzadeh, Seyad Alimohammad
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.9
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    • pp.5287-5291
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    • 2013
  • The human papilloma virus (HPV) causes skin and mucous membrane infections. It crosses from one person to another by skin-to-skin contact, such as sexual contact. There are more than 100 types of HPV that can influence different parts of the body. Some types of HPV can cause cancer (such as cervical or anal cancer) and others can cause warts (such as genital or plantar warts). HPV infection is one of the most common sexually transmitted infections (STIs) in Iran and around the world. Considerable molecular evidence suggests a role for human papilloma virus (HPV) in the pathogenesis of carcinoma. Epidemiological studies on human papilloma viruses (HPVs) infections in general population are critical for the performing of health policy guidelines for developing the strategies to hinder the primary and secondary different cancer. In different parts of Iran, there is a lack of population-based studies to determine the prevalence of HPV in the general population. The aim of this population-based study was therefore to report the prevalence ratse of HPV types among Iranian patients. To study the risk of human papilloma virus (HPV) infection, we managed a retrospective study in Kerman province, southeast of Iran. For this purpose, 410 patients tested for the presence of HPV DNA using PCR and INNo-Lipa assays. HPV DNA was detected in 108 out of 410 patients (26.34%), while it was not detected in any of the control group samples. Patients included 23 (21.1%) males and 86 (78.8%) females. HPV type 6 was the most common (49%) followed by HPV type 16 (10.1%), and also HPV type11 (9.2%). The prevalence of HPV in Iran is comparable to those reported in other regions of the world. In a similar manner, it seems that HPV types 6, 16 and11 are the most common types in Kerman. Additional studies on larger group of patients, particularly in those with pre-invasive forms of disease, are needed to explain the roles of different HPV types in this location of Iran.

Human papilloma virus in oral cancer

  • Kim, Soung Min
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.42 no.6
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    • pp.327-336
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    • 2016
  • Cervical cancer is the second most prevalent cancer among women, and it arises from cells that originate in the cervix uteri. Among several causes of cervical malignancies, infection with some types of human papilloma virus (HPV) is well known to be the greatest cervical cancer risk factor. Over 150 subtypes of HPV have been identified; more than 40 types of HPVs are typically transmitted through sexual contact and infect the anogenital region and oral cavity. The recently introduced vaccine for HPV infection is effective against certain subtypes of HPV that are associated with cervical cancer, genital warts, and some less common cancers, including oropharyngeal cancer. Two HPV vaccines, quadrivalent and bivalent types that use virus-like particles (VLPs), are currently used in the medical commercial market. While the value of HPV vaccination for oral cancer prevention is still controversial, some evidence supports the possibility that HPV vaccination may be effective in reducing the incidence of oral cancer. This paper reviews HPV-related pathogenesis in cancer, covering HPV structure and classification, trends in worldwide applications of HPV vaccines, effectiveness and complications of HPV vaccination, and the relationship of HPV with oral cancer prevalence.

5 Cases of Regressions of Cervical Intraepithelial Neoplasia with High-risk Human Papilloma Virus Treated with Traditional Korean Medicine (한방치료로 호전된 고위험군 인유두종바이러스(HPV) 및 자궁경부 이형성증 5례 증례 보고)

  • Kang, So-Jung;Bae, Kwang-Rok;Hwang, Deok-Sang;Lee, Jin-Moo;Lee, Chang-Hoon;Jang, Jun-Bock
    • The Journal of Korean Obstetrics and Gynecology
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    • v.32 no.1
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    • pp.94-107
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    • 2019
  • Purpose: To report the effect of Traditional Korean medical treatments on 5 patients with cervical intraepithelial neoplasia with high-risk human papilloma virus (HPV). Methods: The patients were diagnosed with cervical intraepithelial neoplasia with High-Risk human papilloma virus. The patients were treated by Traditional Korean Medicine such as herb medication and fumigation therapy. Results: After 3~6 months treatments, cervical intraepithelial neoplasia grades 1-2 lesions regressed and high-risk HPV infections were not detected. Conclusions: The case report shows that Korean medical treatment can be an effective option for treating lower grade of cervical intraepithelial neoplasia with high-risk human papilloma virus.

A Study on the Level of Health Beliefs and Knowledge about Human Papilloma Virus(HPV) Vaccination among Health College Students (보건 계열 대학생의 인유두종바이러스 예방접종 관련 건강신념과 지식정도)

  • Eo, Yong-Sook;Lee, Nae-Young;Kim, Ji-Soo
    • Journal of Fisheries and Marine Sciences Education
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    • v.26 no.2
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    • pp.345-356
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    • 2014
  • The purpose of this study was to identify the knowledge level of human papilloma virus and performance of anti-cervical cancer vaccine among health college student in Korea. A quantitative, descriptive design was used to study 471 students in Ulsan, recruited from April 1 to May 30, 2011. The data were analyzed SPSS program, using descriptive statistics, t-test and ANOVA. The percentage of the participants who received HPV vaccination was 4.0%. The average level of health belief and knowledge about human papilloma virus were 3.05, 5.01 points. Therefore, it is needed to reduce HPV infection through concrete educational programs and advertisement. Also, this educational programs need to include strategies the knowledge of human papilloma virus.

Knowledge, Attitudes and Beliefs about Cervical Cancer and Human Papilloma Virus Vaccination with Related Factors in Turkish University Students

  • Yilmazel, Gulay;Duman, Nuriye Buyukkayaci
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.8
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    • pp.3699-3704
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    • 2014
  • Background: This study aimed to determine knowledge, attitudes and believes about cervical cancer and human papilloma virus (HPV) vaccination with related factors in Turkish university students. Materials and Methods: This descriptive and cross sectional study was conducted between June-July 2013 in Hitit University located in Corum, a rural area to the East of Ankara. The population consisted of 550 university students who were training in first and last year from Faculties of Economics, Theology and Health. We reached 463 volunteer students without selection. The study of data was collected with a 44 item questionaire covering socio-demographic features, knowledge, attitudes and beliefs about cervical cancer, HPV and vaccination. Also for this study ethic committee report was taken from Bozok University. Data were evaluated with the SPSS 17.0 programme using the Ki kare test with P<0.05 accepted as statistically significant. Results: It was seen that there was a statistically significant variation between classrooms and departments of students with knowledge about cervical cancer and human papilloma virus and vaccine (p<0.001; p<0.01; p<0.05). Also we found low attitudes to thinking about taking HPV vaccination of girls and their children in the future. Conclusions: In light of the study findings; it was concluded that knowledge levels, beliefs and attitudes of the university students about cervical cancer, HPV infection and HPV vaccination were low.

Detection of Human papillomavirus & Ebstein-Barr virus in Sinonasal Inverted papilloma (비강 및 부비동의 반전성 유두종에서 인형유두종 및 Ebstein-Barr 바이러스의 검출)

  • Cho, Jae-Shik;Lim, Sang-Chul;Baik, Jun;Jeong, Hyoung-Soo;Shin, Myoung-Seok
    • Korean Journal of Bronchoesophagology
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    • v.5 no.1
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    • pp.49-54
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    • 1999
  • The etiology of inverted papilloma(IP) remains unknown, but several studies have reported that Human Papillomavirus(HPV) may play a role in the pathogensis of sinonasal inverted papilloma(IP). And recent reports demonstrate the possible etiologic role of Epstein-Barr virus (EBV) in sinonasal IP. The aim of this study is to detect HPV and EBV in sinonasal IP, to examine the relationship between HPV subtype and sinonasal IP, to investigate the relation between HPV and EBV. We reviewed 30 cases of sinonasal IP(simple IP 19 cases, IP with dysplasia 8 cases, IP with squamous cell carcinoma 3 cases). Paraffin embedded archival tissue was used in this study. Detection of HPV, EBV were examined by in situ hybridization(ISH) using HPV type 6/11, 16/18, 31/33/35 DNA probe and EBER probe. The HPV was detected in 6(20%) out of 30 cases. The HPV 6/11 was dectected in 4 out of 19 cases of simple IP, HPV 16/18 in 1, HPV 31/33/35 in 1 out of 8 cases of IP with dysplasia respectively. The EBV was not detected in 30 cases. HPV may play a role in the pathogensis of sinonasal inverted papilloma. But EBV is not a etiopathologic factor to be considered in the development of sinonasal IP.

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Determination of Knowledge of Turkish Midwifery Students about Human Papilloma Virus Infection and its Vaccines

  • Genc, Rabia Ekti;Sarican, Emine Serap;Turgay, Ayse San;Icke, Sibel;Sari, Dilek;Saydam, Birsen Karaca
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.11
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    • pp.6775-6778
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    • 2013
  • Human papilloma virus (HPV) is one of the most common sexually transmitted agents and its infection is the most established cause of cervical cancer. Midwives play a key position in the implementation of cervical cancer. This descriptive study aimed to determine the level of knowledge concerning HPV and HPV vaccination among 268 midwifery students. Data were collected between November 15 and 30, 2011, through a self-reported questionnaire. The mean age of participants was $20.75{\pm}1.60$. Among all students, 44.4% had heard of HPV, while 40.4% had heard of HPV vaccinatiob. The relationship between the midwifery student knowledge on HPV and HPV vaccine and their current educational year was significant (p=0.001). In conclusion midwifery students have moderate level of knowledge about HPV and its vaccine and relevant information should be included in their teaching curriculum.

The Factor of Influencing Cervical Cancer and Human Papilloma Virus(HPV) Infection Preventive Behavioral Intention of Nursing Students (간호대학생의 자궁경부암 및 인유두종 바이러스감염 예방행위의도 영향요인)

  • CHOI, Won-Hee;CHO, Gyoo-Yeong
    • Journal of Fisheries and Marine Sciences Education
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    • v.28 no.5
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    • pp.1339-1347
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    • 2016
  • The purpose of this study was to identify factors of influencing cervical cancer and Human papilloma virus(HPV) infection preventive behavioral intention of nursing students. The research design for this study was a descriptive survey design. Data collection was done using self-report questionnaires with 218 nursing students in B city from November 30 to 15 December, 2015. Data were analyzed using percentage, mean, standard deviation, t-test, ANOVA, Pearson's correlation analysis and multiple regression with SPSS Win 21.0 program. The significant factors of cervical cancer and HPV infection preventive behavioral intention was cervical cancer knowledge(${\beta}=.246$, p<.001), health belief about HPV vaccination(${\beta}=-.223$, p<.001), HPV vaccination(${\beta}=.173$, p=.008), and Gynecological Disease History(${\beta}=.145$, p=.026). And these factors explained 15.4% of the variance in the cervical cancer and HPV Infection preventive behavioral intention. In conclusion, the results of this study indicated that it's a need to develop the effective education program in addition to knowledge improvement on HPV and cervical cancer for nursing students.