• Title, Summary, Keyword: HAL

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Kosinostatin, a Major Secondary Metabolite Isolated from the Culture Filtrate of Streptomyces violaceusniger Strain HAL64

  • EI-Naggar, Moustafa Y.
    • Journal of Microbiology
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    • v.45 no.3
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    • pp.262-267
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    • 2007
  • During a screening program, an actinomycete strain isolated from the Egyptian soil was investigated for its potential to show antimicrobial activity. The identification of this isolate was performed according to spore morphology and cell wall chemo-type, which suggested that this strain is a streptomycete. Further cultural, physiological characteristics and the analysis of the nucleotide sequence of the 16S rRNA gene (1480 bp) of this isolate indicated that this strain is identical to Streptomyces violaceusniger (accession number EF063682) and then designated S. violaceusniger strain HAL64. In its culture supernatant, this organism could produce one major compound strongly inhibits the growth of Gram-positive but the inhibition of Gram-negative indicator bacteria was lower. The antibiotic was separated by silica gel column chromatography and then purified on a sephadex LH-20 column and finally the purity was checked by HPLC. The chemical structure of the purified compound was determined using spectroscopic analyses (molecular formula of $C_{33}H_{32}N_{2}O_{10}$ and molecular weight of 617.21) and found to be identical to the kosinostatin, a quinocycline antibiotic which is known to be produced by Micromonspora sp. TP-A0468 (Igarashi et al., 2002) and to quinocycline B isolated from Streptomyces aureofaciens (Celmer et al., 1958). Although the antibiotic is known, the newly isolated strain was able to produce the antibiotic as a major product providing an important biotechnological downstream advantage.

Design and Implementation of HAL and Java API for Embedded System (임베디드 시스템을 위한 HAL과 JAVA API 설계 및 구현)

  • Lee, Jin-Kwan;Lee, Dae-Hyung;Jung, Kyu-Cheol;Lee, Jong-Chan;Park, Ki-Hong
    • Convergence Security Journal
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    • v.8 no.1
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    • pp.57-65
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    • 2008
  • The implement of JAVA API for supporting the embedded system is capable of developing the object oriented system with code reuse because the developer is able to use JAVA in the embedded system. The system dependant parts for implementing JAVA API are realized from a native function. In this paper, we devide JAVA API into the platform-independent JAVA part and platform-dependent native part for the implementation of JAVA API to manage the linux based embedded system devices, and focus on the control of the embedded system devices using JAVA API.

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Implementation of Linux RTAI Open CNC System Based on EtherCAT Network (EtherCAT 네트워크 기반 리눅스 RTAI 개방형 CNC 시스템 구현)

  • Park, Sung-Mun;An, Cheol-Jin;Kim, Hyoungwoo;Yi, Hyun-Chul;Choi, Joon-Young
    • Journal of Institute of Control, Robotics and Systems
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    • v.21 no.10
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    • pp.977-981
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    • 2015
  • We propose a method for the implementation of an EtherCAT communication bus in a Linux-based open source Computerized Numerical Control (CNC) system. Recently, increasingly more CNC systems support real-time Ethernet protocols such as EtherCAT, which is a high-performance industrial communication protocol. For real-time CNC control over an Ethernet-based protocol, an additional layer driver needs to be implemented between the CNC system and the master of industrial communication protocol. Among the various solutions for the connection layer driver, we employ a Hardware Abstraction Layer (HAL) driver based on Linux. The operation of the implemented CNC system is demonstrated and confirmed by Hal Meter, which is used to observe the pins, signals, or parameters of HAL.

EFFECTS OF CYP2D6*10 GENOTYPE AND CYP3A4 INHIBITION ON THE DISPOSITION AND NEUROLOGICAL SIDE EFFECTS OF HALOPERIDOL IN HUMAN SUBJECTS

  • Park, Ji-Young;Shon, Ji-Hong;Yoon, Young-Ran;Kim, Kyung-Ah;Kim, Min-Jung;Shim, Ju-Chul;Cha, In-June;Shin, Jae-Gook
    • Proceedings of the Korean Society of Toxicology Conference
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    • pp.149-149
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    • 2001
  • Cytochrome P450 (CYP) 2D6 and CYP3A4 have been reported to be involved in the major metabolic pathways and formations of neurotoxic metabolites (HPP$\^$+/, RHPP$\^$+/) from haloperidol (HAL). However, no in vivo study has been addressed to the involvement of both CYP isoforms on the formation of toxic HAL metabolites.(omitted)

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Design of a High-Level Synthesis System for Automatic Generation of Pipelined Datapath (파이프라인 데이터패스 자동 생성을 위한 상위수준 합성 시스템의 설계)

  • 이해동;황선영
    • Journal of the Korean Institute of Telematics and Electronics A
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    • v.31A no.3
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    • pp.53-67
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    • 1994
  • This paper describes the design of a high-level synthesis system. SODAS-VP. which automatically generates hardwares executing operation sequences in pipelined fashion.Target architecture and clocking schemes to drive pipelined datapath are determined, and the handling of pipeline hazards which degrade the performance of pipeline is considered. Partitioning of an operation into load, operation, and store stages, each of which is executed in partitiones control step, is performend. Pipelinecl hardware is generated by handling pipeline hazards with internal forwarding or delay insertion techniques in partitioning process and resolving resource conflicts among the partitioned control steps with similarity measure as a priority function in module allocation process. Experimental results show that SODAS-VP generates hardwares that execute faster than those generated by HAL and ALPS systems. SODAS-VP brings improvement in execution speed by 17.1% and 7.4% comparing with HAL and ALPS systems for a MCNC benchmark program, 5th order elliptical wave filter,respectively.

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A Study on Operator Allocation and Binding by ILP (ILP기법을 이용한 연산자할당 및 바인딩에 관한 연구)

  • 신인수;인근만
    • Journal of the Korea Society of Computer and Information
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    • v.4 no.1
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    • pp.7-14
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    • 1999
  • In this paper, we deals with operator allocation and binding in high-level synthesis. We proposed a new methode to allocation and bind for scheduled operations on each control step after scheduling. Especially, we take account ILP formulation in order to get optimal allocation and binding result. Experiment was done on the HAL DFG model of Differential Equation, to show it's effectiveness.

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Web-based Face to Face Education System HALS (웹 기반 면대면 교육시스템 HALS - HALS 활용에 대한 평가 및 분석 -)

  • Hong Jun-Hee;Son Won-Gi;Choi Jung-In
    • Journal of Engineering Education Research
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    • v.3 no.1
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    • pp.3-11
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    • 2000
  • HALS (Hypermidia Aided Learning System) is very useful computer networking educational system in knowledge-driven society, and has been developed by Kyungwon University. This system has three characteristics; 1) face-to-face learning, 2) ultra high-speed information networking, 3) web-based hypermedia courseware. So, the purpose of this paper is to introduce the application to engineering educational program (electrical engineering: electric power system, control system). For this purpose it is described the definition and characteristics of HALS. Next, it is represented the model of electrical engineering educational program applied to HALS and the developed courseware.

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A Study on UV Degradation of SBR and NR Containing Polymeric UV Stabilizer (고분자형 자외선 안정제를 함유한 SBR과 NR의 UV 노화 거동에 관한 연구)

  • Kaang, Shin-Young;Nam, Kyoung-Tae;Hong, Chang-Kook;Chae, Kyu-Ho
    • Elastomers and Composites
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    • v.41 no.3
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    • pp.182-193
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    • 2006
  • The retardation effects of a new polymeric UV stabilizer, DGEBA-HALS, on the UV degradation of SBR and NR were investigated in this study. The UV degradation behaviors of three different rubber compounds, without any photostabilizer and with commercial Cyabsorb UV-3529 and DGEBA-HALS, were compared. Also, the physical characteristics such as Young's modulus, tensile strength, blow-off deformation and crosslink density were examined. The Young's modulus was increased by UV irradiation for all samples, and the tensile strength, after UV irradiation, of the compound with UV stabilizer was better than that of the compound without stabilizer. Especially, the tensile strength of UV irradiated NR was improved by adding DGEBA-HALS. The results of blow-off deformation were in accord with those of Young's modulus. The degree of transmission of SBR compounds obtained from UV-vis transmission spectra was improved about 4% by adding the UV stabilizer. Commercial Cyabsorb UJV-3529 and DGEBA-HALS showed similar trends of transmission. The SEM photographs of SBR surface showed that the size of cracks created by UV irradiation became smaller by adding UV stabilizer. In particular, it is observed that the stabilization effect of DGEBA-HALS was better than that of commercial Cyabsorb UV-3529.