• Title, Summary, Keyword: External irradiation

Search Result 228, Processing Time 0.041 seconds

GaAsP 다이오드 조사에 따른 창상치유 효과

  • Kim, Tae-Gon;Kim, Yeong-Pyo;Lee, Ho-Sik;Park, Yong-Pil;Cheon, Min-U
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
    • /
    • /
    • pp.240-240
    • /
    • 2009
  • We developed the low level laser therapy(LLLT) apparatus for external injury cure using a GaAsP Diode. This equipment was fabricated by using GaAsP diode and a microcontroller, and designed to enable us to control light irradiation timer, and frequency. In this paper, the designed device was used to find out how GaAsP diode light source affects the skin wound of RAT. In the experiment, $1cm^2$ wounds on the External injury of RAT were made. Light irradiation RAT and none light irradiation RAT divided, each RAT was irradiated 20 min a day for 9 days. In result, compared with none light irradiation RAT, the lower incidence of inflammation and faster recovery was shown in light irradiation RAT.

  • PDF

One Case of Esophageal Cancer Treated with High Dose Rate ICR (고 선량률 강내 치료기를 이용한 식도암 치험 1례)

  • Kim, Kyeung-Ae;Kim, Sung-Kyu;Shin, Sai-One;Kim, Myung-Se
    • Yeungnam University Journal of Medicine
    • /
    • v.5 no.1
    • /
    • pp.147-151
    • /
    • 1988
  • Esophageal cancers are highly malignant neoplasms. Prognosis of esophageal cancer treated by external irradiation alone is rather poor because of local recurrence and distant metastasis. Recently intracavitary irradiation has been used as a boost therapy after external irradation to optain better local control. One case of esophageal cancer has been treated by high dose rate remote-controlled afterloading unit as boost therapy after external irradiation. The result was excellent in short term follow up esophagogram but esophageal bleeding and esophagotracheal fistula were noted in further follow up examination after inappropriate posttreatment management including insufficient chemotherapy due to poor general condition. We reviewed possible causes of esophageal bleeding and esophagotracheal fistula after external irradiation and high dose rate ICR.

  • PDF

4-channel Light Medical Therapy Apparatus for External Injury Cure (체외 상처 치유를 위한 4-채널 광 치료기)

  • Cheon, Min-Woo;Kim, Seong-Hwan;So, Keum-Young;Moon, Young-Lae;Mun, Seong-Pyo;Park, Yong-Pil;Lee, Ho-Sik;Kim, Tae-Gon
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
    • /
    • v.20 no.8
    • /
    • pp.731-735
    • /
    • 2007
  • We developed the 4channel Light Medical Therapy Apparatus for External Injury Cure using a high brightness LED. This equipment was fabricated using a micro-controller and a high brightness LED, and designed to enable us to control light irradiation time, intensity, frequency and so on, Especially, to control the light irradiation frequency, FPGA was used, and to control the change of output value, TLC5941 was used. Control stage is divided into 4 levels by program. Consequently, the current value could be controlled by the change of level in Continue Wave(CW) and the output of a high brightness LED could be controlled stage by stage. Compared with one LED irradiation, several LEDs irradiation could increase optical power.

The effect of 470nm LED Irradiation on skin injury of RAT (470nm LED 광이 RAT 피부결손에 미치는 효과)

  • Cheon, Min-Woo;Kim, Seong-Hwan;Park, Yong-Pil;Lee, Ho-Shik;Kim, Young-Pyo;Kim, Tae-Gon;Lee, Hee-Keb
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
    • /
    • /
    • pp.416-417
    • /
    • 2008
  • This paper performed the basic study for developing the Photodynamic Therapy Equipment for medical treatment. We developed the 4channel light medical therapy apparatus for external injury cure using a LED light source. This equipment was fabricated by using microcontroller, and designed to enable us to control light irradiation timer, intensity and reservation. In this paper, the designed device was used to find out how 470nm LEDs light source affects the skin wound of RAT. In the experiment, $1cm_2$ wounds on the External injury of RAT were made. Light irradiation RAT and none light irradiation RAT divided, each RAT was irradiated one hour a day for 15 days. In result, compared with none light irradiation RAT, the lower incidence of inflammation and faster recovery was shown in light irradiation RAT.

  • PDF

The Role of External Irradiation for the Locally Advanced Papillary Thyroid Cancers (국소적으로 진행된 갑상선 유두암에서의 방사선치료의 역할)

  • Kim Tae-Hyun;Yang Dae-Sik;Kim Chul-Yong;Choi Myung-Sun
    • Radiation Oncology Journal
    • /
    • v.17 no.3
    • /
    • pp.187-194
    • /
    • 1999
  • Purpose : The aim of this study is to look for the possible efficacy of external irradiation for locally advanced papillary thyroid cancers (stage pT4 or Nl ). Methods and Materials : From August 1981 through September 1997, 91 Patients with locally advanced papillary thyroid cancers (stage pT4 or Nl ) have been treated with external irradiation and followed up at our clinic. All of the patients have been treated with surgical resection. After surgery, 23 patients received postoperative external irradiation with or without ablative radioiodine therapy, whereas the other 68 patients were treated with ablative radioiodine therapy alone. Distributions of sex, age, and stage were comparable in both irradiated and nonirradiated groups. Multivariate analysis of the influence by age, sex, stage, ablative radioiodine therapy and external irradiation on local control were peformed by using Cox's proportional hazard model. Results : Overall survival rates at 7 years were of no significant difference in both groups. There were $98.1\%$ for no RT group and $90\%$ for RT group (p=0.506). 5-year local control rates were significantly different, these were $95.2\%$ for RT group and $67.5\%$ for no RT group (p=0.0408). An analysis of the prognostic factors, age, sex, stage, and RAI were not significant variables, except for the external irradiation. Conclusion : Adjuvant postoperative external irradiation did not affect overall survival, but significantly improved local control in the patients with locally advanced papillary thyroid cancers (stage pT4 or lympy node involvement).

  • PDF

Electrobehavioral and Pathological Characteristics in Cerebral Cortical Dysplasia Induced by External Irradiation in the Rat (방사선조사에 의해 피질이형성증 백서의 전기행동학적, 병리조직학적 특징)

  • Choi, Ha-Young
    • Journal of Korean Neurosurgical Society
    • /
    • v.29 no.7
    • /
    • pp.861-867
    • /
    • 2000
  • Purpose : Neuronal migration disorder(NMD) is a major underlying pathology of patients with intractable epilepsy. The role of NMD on seizure susceptibility or epileptogenecity, however, has not been documented. Methods : External irradiation of total amount of 250 cGY was performed to the fetal rats on days 16(E16) and 17(E17) of gestation. After delivery, the rats of 230-260g were decapitated for the histopathologic study. Epileptog-enecity of the NMD was studied by observing electroclinical events after intraperitoneal kainic acid(KA) injection in the control rats and NMD rats. Results : Histopathologic findings revealed focal and/or diffuse cortical dysplasia consisting of dyslamination of the cerebral cortex and appearance of the cytomegalic neurons, neuronal heterotopia in the periventricular white matter, dispersion of the pyramidal layer and the dentate gyrus of the hippocampus, and agenesis of the corpus callosum. Abnormal expression of neurofilaments protein(NF-M/H) was characteristically observed in the dysplastic neurons of the neocortex and hippocampus. Early ictal onset and prolonged ictal activity on EEG and clinical seizures were observed from the NMD rats unlike with the control rats. Conclusions : Exteranl irradiation on the fetal rats produced NMD. And the rats with NMD were highly susceptible to kainic acid provoked seizures. This animal model would be useful to study the pathophysiology of clinically relevant NMDs.

  • PDF

I-V Characteristics According to Irradiation for Photovoltaic Systems (태양광 시스템의 일사량에 따른 전압-전류 특성)

  • Lee, Ying;Choi, Yong-Sung;Zhang, You-Sai;Lee, Kyung-Sup
    • Proceedings of the KIEE Conference
    • /
    • /
    • pp.177-179
    • /
    • 2009
  • Solar, as an ideal renewable energy, it has inexhaustible, clean and safe characteristics. However, solar energy is an extreme intermittent and inconstant energy source. In order to improve the photovoltaic system efficiency and utilize the solar energy more fully, and the DC current varies with the irradiation, it is necessary to study the characteristics of photovoltaic I-V according to the external factors. This paper presents the analysis of characteristics of photovoltaic I-V according to the irradiation.

  • PDF

CHARACTERISTICS OF THE PNEUMATIC TRANSFER SYSTEM AND THE IRRADIATION HOLE AT THE HANARO RESEARCH REACTOR

  • Chung, Yong-Sam;Kim, Sun-Ha;Moon, Jong-Hwa;Kim, Hark-Rho;Kim, Young-Jin
    • Nuclear Engineering and Technology
    • /
    • v.38 no.6
    • /
    • pp.585-590
    • /
    • 2006
  • This paper describes the results of an irradiation test and the specifications of the pneumatic transfer system (PTS) in the NAA #3 irradiation hole at the HANARO research reactor, which was reinstalled after some modifications of the operation mode at the end of 2004. The outer and inner diameters of the PE transfer tube are 34.1 and 27.5 mm, respectively. PE rabbit was used for sample irradiation. The $N_2$ gas pressure of the PTS lines was adjusted to 0.75 bar. The average sending time to the reactor was $8.5{\pm}0.3$ s and the average receiving time back to the receiver was $3.2{\pm}0.2$ s. The internal and external temperature of the irradiation tube was measured in a range of 50 to $80^{\circ}C$ for a 40 s to 80 s irradiation time, respectively. The optimum irradiation time was estimated to be less than 80 s. The thermal, epithermal and fast neutron flux at 30 MW thermal power were $1.42{\pm}0.01{\times}10^{14},\;1.51{\pm}0.04{\times}10^{13}$ and $9.48{\pm}0.69{\times}10^{11} n{\cdot}cm^{-2}{\codt}s^{1-}$, respectively. The cadmium ratio was approximately 9.40. The data obtained will be applied to supplement user information and for reactor management.

The evaluation on the biological safety of diagnostic ultrasound using radiation-induced apoptosis in the external granular layer of mouse cerebellum (마우스 소뇌과립층의 apoptosis를 지표로 한 진단용 초음파의 안전성 검증)

  • Oh, Heon;Lee, Song-eun;Yang, Jung-ah;Jo, Sung-kee;Chung, Chi-young;Son, Chang-ho;Kim, Sung-ho
    • Korean Journal of Veterinary Research
    • /
    • v.39 no.3
    • /
    • pp.628-634
    • /
    • 1999
  • We have studied, by a nonisotopic in situ end-labeling(ISEL) technique, frequency of apoptosis in the external granular layer(EGL) of the cerebellum of immature mice by ${\gamma}$-rays irradiation from $^{60}Co$ or diagnostic ultrasound exposure. The total number of normal cells and cells showing morphological features of apoptosis were counted. The frequency of apoptotic cells was expressed as a percentage of the total number of cells in EGL. The extent of changes following 200 cGy(1090 cGy/min) was studied at 2, 4, 6, 8, 12, or 24 hours after exposure. The maximal frequency was found 6~8 hours after exposure. The immature mice that received 18, 36, 54, 108, 198, 396 cGy of ${\gamma}$-rays or diagnostic ultrasound(7.5MHz, 4.2mW, $I_{SPTA}=7.9mW/cm^2$, $I_{SPTA}=114.3W/cm^2$) for 10 or 30 minutes were examined 6 hours after irradiation. Measurements performed after ${\gamma}$-ray irradiation showed a dose-related increase in apoptotic cells in each of the mice studied. The dose-response curves were analyzed by a linear-quadratic model ; frequency of apoptotic cell in the EGL was y = $(0.1349{\pm}0.01175)D$+$(-0.0001522{\pm}0.0000334)D^2$+0.048($r^2$ = 0.981, D = dose in cGy). In the experiment of ultrasound exposure, the frequency of apoptotic cell was $0.106{\pm}0.130$(10 minutes exposure) and $0.167{\pm}0.220$(30 minutes exposure). We estimated the relative dose of the yield from the experiment with ultrasound by substituting the yield from ultrasound exposure into the curve from the ${\gamma}$-irradiation. The relative dose of ultrasound exposure compared with ${\gamma}$-irradiation were 0.432 cGy(10 minutes exposure) and 0.885 cGy(30 minutes exposure). We have found that there is no evidence to indicate that diagnostic ultrasound involves a significant risk.

  • PDF

Effects of External Whole-Body gamma-Irradiation on Embryos in Mice (Cobalt-60 gamma 선(線) 외부전신조사(外部全身照射)가 생쥐의 태아(胎兒)에 미치는 영향(影響))

  • Sung, Jai Ki
    • Korean Journal of Veterinary Research
    • /
    • v.15 no.1
    • /
    • pp.9-13
    • /
    • 1975
  • In oder to investigate the effects of cobalt-60 gamma irradiation on the postnatal body gains and the other influece of the pregnant mice were subjected to single whole-body gamma irradiation externally. The results obtained were as follows: 1. The all mice of 400, 600, and 800 Rads gamma-irradiated groups showed abortion after prenatal gamma irradiation within 4 to 9 days. 2. There were significant differences of the postnatal body gains of mice between the control and treated groups (100 Rads and 200 Rads gamma irradiation). 3. The relation between gamma-irradiated doses and the postnatal growth rates of mice were inversly proportional.

  • PDF