• Title, Summary, Keyword: E-Science

Search Result 21,500, Processing Time 0.064 seconds

Taxonomic status of three taxa of Elsholtzia (E. hallasanensis, E. springia, and E. splendens var. fasciflora) (Lamiaceae) based on molecular data

  • Lee, Chang Shook;Hwang, Kung Ae;Kim, Jin Ok;Suh, Hyoung Min;Lee, Nam Sook
    • Korean Journal of Plant Taxonomy
    • /
    • v.41 no.3
    • /
    • pp.259-266
    • /
    • 2011
  • Elsholtzia hallasanensis, E. springia, and E. splendens var. fasciflora (Lamiaceae) were reported recently as new species or new varieties of E. splendens according to their morphological characteristics. To reappraise the taxonomic status of these additional taxa and to determine the relationships between all Korean Elsholtzia taxa except E. saxatilis, which is distributed in North Korea, molecular studies based on the nrDNA (ITS) and cpDNA (rpl16, and trnH-psbA) sequences of seven taxa of Elsholtzia and one outgroup were carried out. The molecular data support that E. angustifolia and E. minima are distinct species from E. splendens and E. ciliata, respectively, because they have several private marker genes and show monophyly. The molecular data also support that E. splendens has a very close taxonomic relationship with both E. hallasanensis and E. springia. We found that E. splendens var. fasciflora, with multiple inflorescence, was based on several private marker genes and on the monophyly of its trees, suggesting that it can be considered as a variety. Elsholtzia springia, with the same sequences and the same morphological characteristics with E. hallasanensis after transplanting, should be treated as a synonym of E. hallasanensis. Moreover, we consider the taxonomic status of E. hallasanensis as E. splendens var. hallasanensis (Y. Lee) N.S. Lee & C.S. Lee, stat. nov.

HPV 16 E6/E7 Transgenic Mice Have Hyperkeratosis and Modulated Antioxidant Enzyme Activities

  • Kim, Myoung-Ok;Lee, Eun-Ju;Kim, Sung-Hyun;Park, Jun-Hong;Cho, Kyoungin;Jung, Boo-Kyung;Kim, Hee-Chul;Hwnag, Sol-Ha;Kim, Sun-Jung;Ryoo, Zae-Young
    • Proceedings of the Korean Society of Developmental Biology Conference
    • /
    • /
    • pp.106-106
    • /
    • 2003
  • Human papillomavirus type 16(HPV16) has been known to the major factor for the development of uterine cervical carcinomas. We have extended these studies to investigate the in vivo activities of HPV-16 E6/E7 when expressed in squamous epithelia of transgenic mice. Grossly, hK14HPV16E6/E7 transgenic mice had multiple phenotypes, including wrinkled skin that was apparent prior to the appearance of hair on neonates, thickened ears, and loss of hair in adults. In the transgenic mice, the wrinkled skin phenotype on the body and legs died at the age of 3-4 weeks. Histological analysis of demonstrated that E6/E7 causes epidermal hyperplasia in multiple transgenic lineages with high penetrance. This epithelial hyperplasia was characterized by an expansion of the proliferating compartment and an expansion of the keratinocyte and was associated with hyperkeratosis. These transgenic mice expressed E6/E7 transgene mainly in skin, heart, pancreas and kidney. Hyperplasia was found at the skin. The enzyme activities of GR, GPx and CuZnSOD were measured from the transgene cause keratinocyte at the skin. The specific enzyme activities were significantly higher in transgenic mice skin compared to the normal mice skin. Thus these transgenic mice may be useful for the develpment of antioxidant enzymes or other therapies for HPV-associated hyperkeratosis.

  • PDF

Functional Implications of the Conserved Action of Regulators of Ribonuclease Activity

  • Yeom, Ji-Hyun;Shin, Eun-Kyoung;Go, Ha-Young;Sim, Se-Hoon;Seong, Maeng-Je;Lee, Kang-Seok
    • Journal of Microbiology and Biotechnology
    • /
    • v.18 no.8
    • /
    • pp.1353-1356
    • /
    • 2008
  • RNase E (Rne) plays a major role in the decay and processing of numerous RNAs in E. coli, and protein inhibitors of RNase E, RraA and RraB, have recently been discovered. Here, we report that coexpression of RraA or RraB reduces the ribonucleolytic activity in rne-deleted E. coli cells overproducing RNase ES, a Streptomyces coelicolor functional ortholog of RNase E, and consequently rescues these cells from growth arrest. These findings suggest that the regulators of ribonuclease activity have a conserved intrinsic property that effectively acts on an RNase E-like enzyme found in a distantly related bacterial species.

A Study on the System of Environmental Education major in the Granduate School of Education (교육대학원 [환경교육전공]의 체제에 관한 연구)

  • 강환국
    • Hwankyungkyoyuk
    • /
    • v.8 no.1
    • /
    • pp.122-137
    • /
    • 1995
  • The Environmental Education(E.E.) is very important field in Elementary and Secondary School. And the first important problem of E.E. in school is no special teacher. This thesis is a study on the system of E.E. major in the graduate school of education. 1. The aims of E.E. major are training of E.E. teacher and developing research of E.E. 2. The curriculum of E.E. major is consisted of E.E. theory and E.E. content. 3. The student of E.E. major is admited a university graduate of social science and natural science department. 4. The professor of E.E. major is organized a specialist of E.E.

  • PDF

The Status of e-Business in Korea Forest Product Industries (한국목재산업에 있어 e-Business의 활용)

  • Kim, Se-Bin;Kwak, Kyung-Ho
    • Korean Journal of Agricultural Science
    • /
    • v.30 no.1
    • /
    • pp.20-30
    • /
    • 2003
  • This study was carried out to examine the e-Business status of Korea Forest Product Industries and to propose the development. The use level of e-Business in korea forest product industries have stayed in internal company information network integration stages. But lots of companies located in the insufficient of e-Business models, the lack of qualified staffs, and the shortage of e-Business operating technology and implementation. As the result of this study, the followings must be considered; 1. For the promotion of e-Business use, it is needed to maintain price competitiveness, quality competitiveness, and market correspondence capacity. 2. For the settlement of e-Business models, it is important to connect information network among cooperation companies as like forest products standardize, common database, and standard electronic catalogue. Also, it needed developing program to strengthen the competitiveness of forest product industries, expanding to outsourcing and affiliated companies.

  • PDF

Direct characterization of E2-dependent target specificity and processivity using an artificial p27-linker-E2 ubiquitination system

  • Ryu, Kyoung-Seok;Choi, Yun-Seok;Ko, Jun-Sang;Kim, Seong-Ock;Kim, Hyun-Jung;Cheong, Hae-Kap;Jeon, Young-Ho;Choi, Byong-Seok;Cheong, Chae-Joon
    • BMB Reports
    • /
    • v.41 no.12
    • /
    • pp.852-857
    • /
    • 2008
  • Little attention has been paid to the specificity between E2 and the target protein during ubiquitination, although RING-E3 induces a potential intra-molecular reaction by mediating the direct transfer of ubiquitin from E2 to the target protein. We have constructed artificial E2 fusion proteins in which a target protein (p27) is tethered to one of six E2s via a flexible linker. Interestingly, only three E2s (UbcH5b, hHR6b, and Cdc34) are able to ubiquitinate p27 via an intra-molecular reaction in this system. Although the first ubiquitination of p27 (p27-Ub) by Cdc34 is less efficient than that of UbcH5b and hHR6b, the additional ubiquitin attachment to p27-Ub by Cdc34 is highly efficient. The E2 core of Cdc34 provides specificity to p27, and the residues 184-196 are required for possessive ubiquitination by Cdc34. We demonstrate direct E2 specificity for p27 and also show that differential ubiquitin linkages can be dependent on E2 alone.

ADAPTIVE SLIDING WINDOW METHOD FOR TURBO CODES IN CDMA CELLULAR SYSTEM WITH POWER CONTROL ERROR

  • Park, Sook-Min;Yoon, Sang-Sic;Kim, Sang-Wu;Lee, Kwyro
    • Proceedings of the IEEK Conference
    • /
    • /
    • pp.565-568
    • /
    • 2003
  • This paper presents a method that can be used to reduce the decoding computational complexity in turbo codes. To reduce the decoding complexity we proposed an adaptive sliding window method which control the learning period of Viterbi sliding window method depending on channel signal to interference ratio (SIR). When received signal to interference ratio (SIR) is relatively high, we can reduce the decoding complexity without a noticeable degradation of BER performance at CDMA cellular system with power control error.

  • PDF

Inquiry Problem Solving Characteristics among Categories with Science Process Skills and Concepts by High School Student's Protocol Analysis (고등학생의 프로토콜 분석을 통한 과학 탐구능력과 개념 중심의 탐구능력 대범주별 과학 문제 해결 특성)

  • Lee, Hang-Ro
    • Journal of The Korean Association For Science Education
    • /
    • v.19 no.3
    • /
    • pp.355-366
    • /
    • 1999
  • In this study, the characteristics of science inquiry problem solving were analyzed in the interactions between science process skills and science concepts by each related its category. Nine types of problem solving, which were based on two elements and the thinking aloud were found largely by protocol analysis, but six types when integrated similar thinking processes. There were quite differences in the representative types between students who succeeded and failed when science inquiry items were solved in the abilities of recognizing problems and generating hypotheses or those of drawing conclusions and evaluating. But there were not complete differences in those types between students who succeeded and failed when they were solved in the abilities of designing and performing experiments or those of interpreting and analyzing data. The data were divided into independent variables: $D_1,\;D_2,\;D_3,\;D_4,\;D$ and $C_1,\;C_2,\;C_3,\;C_4,\;C$ and dependant variables; $E_1,\;E_2,\;E_3,\;E_4,\;E$. The former consisted of the content-free science process skill achievement levels by each category of science inquiry skill and the science concept achievement levels, the latter the science inquiry problem achievement levels by each category of science inquiry skill. The regression equations were acquired within the 0.05 significant level by regression analysis: $E_1=0.03+0.16D_1+0.29C_1,\;E_2=-0.203+0.21D_2+0.45C_2,\;E_3=-0.32+0.13D_3+0.47C_3,\;E_4=0.61+0.09D_4+0.29C_4,\;E=-1.41+0.13D+0.47C$(E : the achievement of science problems, D : the achievement of science process skills, C : the achievement of science concepts).

  • PDF

Online Searching Behavior of Social Science Researchers' in IR Interfaces of E-journal Database Systems: A Study on JMI, JNU, and DU

  • Kumar, Shailendra;Rai, Namrata
    • Journal of Information Science Theory and Practice
    • /
    • v.1 no.4
    • /
    • pp.48-66
    • /
    • 2013
  • The aim of this study is to examine the user's online searching behavior in IR interfaces of e-journal database systems. The study is purely based on survey methods and tries to analyse the online searching behavior of respondents of social science disciplines who were doing research in three target central universities of Delhi (i.e. DU, JMI, and JNU). For measuring the responses of the respondents in IR interfaces of e-journal database systems, a total of 396 questionnaires were distributed among the students and out of all, 305 responses were used for the study. The findings of the study reveal that most of the students were not using all the facilities offered in IR interfaces of e-journal database systems for their retrieval process and also encourages menu based searches rather than command based searching.

Anti-Biofilm Activities of Manuka Honey against Escherichia coli O157:H7

  • Kim, Su-Yeon;Kang, Seok-Seong
    • Food Science of Animal Resources
    • /
    • v.40 no.4
    • /
    • pp.668-674
    • /
    • 2020
  • Manuka honey (MH) has been shown anti-bacterial activity against several pathogenic bacteria. However, the inhibitory effect of MH on biofilm formation by Escherichia coli O157:H7 has not yet been examined. In this study, MH significantly reduced E. coli O157:H7 biofilm. Moreover, pre- and post-treatment with MH also significantly reduced E. coli O157:H7 biofilm. Cellular metabolic activities exhibited that the viability of E. coli O157:H7 biofilm cells was reduced in the presence of MH. Further, colony forming unit of MH-treated E. coli O157:H7 biofilm was significantly reduced by over 70%. Collectively, this study suggests the potential of anti-biofilm properties of MH which could be applied to control E. coli O157:H7.