• Title, Summary, Keyword: Dongui Bogam

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A Study on the Applications of Zingiberis siccatum Rhizoma Mainly Blended Prescription in Dongeuibogam (동의보감(東醫寶鑑) 중(中) 건강(乾薑)이 주약(主藥)으로 배오(配伍)된 방제(方劑)의 활용(活用)에 대한 고찰(考察))

  • Yun, Ji Yeon;Yun, Young Gab;Lim, Kyu Sang
    • Herbal Formula Science
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    • v.25 no.3
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    • pp.413-427
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    • 2017
  • Objectives : This report describes 75 studies related to the use of Zingiberis siccatum Rhizoma mainly blended from Dongeuibogam. Methods : The 75 Prescriptions of Consumptive part in DonguiBogam analysed frequency of basic prescriptions, symptoms of prescriptions and the pathology. Results : Prescriptions that Zingiberis siccatum Rhizoma was taken as a monarch drug are utilized for 25 therapeutic purposes, for example, cold disease, stool disease, cough disease. In particular, 16.0% of prescriptions appear in the chapter of cold. Prescriptions that utilize Zingiberis siccatum Rhizoma as the main component are used in the treatment of cold, stool and cough disease. Zingiberis siccatum Rhizoma is used in pathogenic factors such as weakness cold and cold strength and used in pathology related to the spleen and stomach system. The dosage of Zingiberis siccatum Rhizoma is 5pun(about 1.88g) to 4nyang(about 150.4g), however 1don(about 3.75g) has been taken the most for clinical application. Ijungtang is the most useful base prescriptions which use the Zingiberis siccatum Rhizoma as the main ingredient. Conclusions : As a result of Study on Analysis all Prescriptions of Zingiberis siccatum Rhizoma in DonguiBogam. We can understand more about basic prescriptions, symptoms of prescriptions and the pathology that are using for Zingiberis siccatum Rhizoma.

The Effect of Samchoolgunbitanggamibang of the growth of rats (삼출건비탕가미방(蔘出健脾湯加味方)이 흰쥐의 성장에 미치는 영향)

  • Beak, Jung-Han;Koo, Jin-Suk
    • The Journal of Pediatrics of Korean Medicine
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    • v.20 no.1
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    • pp.49-67
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    • 2006
  • Objectives : The purpose of this study is to find out the effect of antioxidation related to aging of Cheongeumyeonsudan which is written on Dongui-bogam experimentally. Method : 14 weeks aged SD albino rats were separated into uncontrolled group, controlled group and CGY group. As controlled and CGY groups were induced aging by subcutaneous injection of D-galactose, at the same time we administered the extract of Cheongeumyeonsudan to CGY group for 6 weeks. After then we drew blood from each group, and took measurements; the activity of SOD, GSH-px, catalase in erythrocytes, TBARS value, concentration of total lipid, tryglycende, total cholesterol, HDL-cholesterol in blood plasma. Results : The activities of SOD, GSH-px in erythrocytes were significantly increased in the CGY group compared with control group. The activity of catalase showed a tendency to increase, but it was nor remarkable. The concentration of total lipid, the values of TBARS and total cholesterol was significantly decreased in the CGY group compared with control group, and the concentration of plasma HDL-cholesterol was not remarkable. The concentration of tryglycende in plasma showed a tendency to decreased. Conclusions : it is suggested that Cheongeumyeonsudan decreased the activities of free radical, the concentration of lipid in plasma and generate enzyme which form lipid peroxide.

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A Study on the Current education of Oriental Medical Classics in Korea;A Study focused on Hwangje-Naegyeong(黃帝內經) (원전학 교육 현황에 관한 연구;"황제내경(黃帝內經)"을 중심으로)

  • Kim, Do-Hoon
    • Journal of Korean Medical classics
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    • v.19 no.4
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    • pp.101-112
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    • 2006
  • For the purpose of profound comprehension of the Current education of Oriental medical classics in Korea, I investigated the results of direct survey of the Current education of Oriental medical classics from each professor, and came to following conclusions. 1. The education of Oriental medical classics mainly lasts for 2 years. Students have average 6.59 hours of lecture every week. The rate of full service professor reaches 74.4%. But the department of Oriental medical classics in every college takes charge of many subjects which are related to Oriental medical classics, so the appointment of large number of full service professor is essential for the improvement of educational environment of Oriental medical classics. 2. After the publishing of the common textbook of Oriental medical classics, it gradually became the main textbook. But it is necessary that we should complement the textbook and it is also necessary that we should develop another textbook for Nangyeong(難經). 3. Most professors emphasize on the cultivation of the ability which enables Oriental medical thought through precise comprehension of original text. By the way, for the purpose of motivation of studying Oriental medical classics, it is necessary to develop a lecture which is related to clinical medicine. From the same context it is also necessary to read clinical original text such as Dongui-bogam(東醫寶鑑) and Uihakimmun(醫學入門) in class.

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A Bibliographic Study on Introduction to Medicine (Euihak-ipmun) in Joseon Dynasty (조선 간행 『의학입문』 판본에 대한 서지학적 연구)

  • Park, Hun-Pyeng
    • The Journal of Korean Medical History
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    • v.30 no.2
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    • pp.33-44
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    • 2017
  • Introduction to Medicine (Euihak-Ipmun), written by Lee Chun of the Ming Dynasty, is a comprehensive medical book brought to Joseon in the 1600s. It directly influenced many medical books written in the Joseon Dynasty of the same period, and became a major citation document of Dongui-Bogam. Introduction to Medicine became a major text for medical education in 1834 and has since been used as a clinical primer of Korean medicine. This article first examines the Joseon's era published version of Introduction to Medicine using documentation of the Diary of the Royal Secretariat (Seungjeongwon Ilgi), and a woodblock list. Based on these investigations, the reviewer examined the existing versions of the book, and focused on various characteristics for comparison. This article reveals facts which include : 1) All editions of Introduction to Medicine published at the present office are published by Jeolla-do provincial office (Jeolla-Gamyeong). 2) The first edition was published before 1636. 3) A finely produced version (Jeongganbon) was published around 1760. 4) The Jeongrijache-iron type publication was published around 1801.

Medical Historic Inquiry On ${\ulcorner}$Yoryak${\lrcorner}$ that Found First (처음 발견된 "요략(要略)"에 대한 의사학적 고찰)

  • Kim, Dae-Hyeng;Ahn, Sang-Woo
    • Korean Journal of Oriental Medicine
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    • v.10 no.2
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    • pp.37-49
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    • 2004
  • In the existing Medical Literatures in Korea and China, there is neither the same book name nor same contents of the Medical Book named ${\ulcorner}$Yoryak(要略)${\lrcorner}$, but in viewing of the different name as written as ${\ulcorner}$GyoinYoryak(敎人要略)${\lrcorner}$, it is considered that written as an unpublished manuscript-book for the purpose of Medical Education in the latter period of Chosun Dynasty. While the author, Songgyesanin(松溪散人) is even anonymous as yet, it is regarded that he was much familiar with medical science as a secluded ascetic aiming for Taoism-like Life In ${\ulcorner}$Yoryak${\lrcorner}$, the contents of Taoism Literature named as ${\ulcorner}$OjangYukbudo(五臟六腑圖)${\lrcorner}$ which was regarded that had been actually initiated since ${\ulcorner}$Euibangyoochui(醫方類聚)${\lrcorner}$ is being quoted thereat, also it attempts to combine with ${\ulcorner}$DonguiBogam(東醫寶鑑)${\lrcorner}$, the typical Medical Literature of Chosun Dynasty. With reference to Cause of Disease, since Chin Moo-Taek(陳無擇) asserted 'Theory of Three-Causes(三因說)' in his Book ${\ulcorner}$Samin Keukilbyungjeung Bangron(三因極一病證方論)${\lrcorner}$, it effects many influences to the coming generation, However, on coming up to ${\ulcorner}$Yoryak${\lrcorner}$, the medical science book of Chosun Dynasty, the 'Theory of Two-Causes(二因說)' which consisted of 'Internal Causes by Seven Emotions' and 'Exterior Causes by Six Harmful Surroundings' is also being asserted. In accordance with this Theory, it refers to the 'Seven Emotions(七情)' as the fundamental factor to possibly weaken the viscera and entrails, and also regards that the Exterior Harmful Surroundings invade to body when the viscera and entrails are under weakened condition. Therefore, since Cause of Disease naming as 'Cause Theory at Neither Interior Nor Exterior' is not tolerable in such Diagnostic System, it is daringly advocating the 'Two Causes Theory', getting free from the viewpoint of 'Three Causes Theory' that Chin Moo-Taek has ever maintained.

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An anti-Dxidative Effect of Cheongeumyeonsudan of Rats Induced Aging by D-Galactose (천금연수단(千金延壽丹)이 노화 유발된 철쥐의 항산화효능에 미치는 영향)

  • Song, Kyoung-Hye;Seo, Jung-Min;Beak, Jung-Han
    • The Journal of Pediatrics of Korean Medicine
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    • v.20 no.1
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    • pp.31-47
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    • 2006
  • Objectives : The purpose of this study is to find out the effect of antioxidation related to aging of Cheongeumyeonsudan which is written on Dongui-bogam experimentally. Method : 14 weeks aged SD albino rats were separated into uncontrolled group, controlled group and CGY group. As controlled and CGY groups were induced aging by subcutaneous injection of D-galactose, at the same time we administered the extract of Cheongeumyeonsudan to CGY group for 6 weeks. After then we drew blood from each group, and took measurements; the activity of SOD, GSH-px, catalase in erythrocytes, TBARS value, concentration of total lipid, tryglycende, total cholesterol, HDL-cholesterol in blood plasma. Results : The activities of SOD, GSH-px in erythrocytes were significantly increased in the CGY group compared with control group. The activity of catalase showed a tendency to increase, but it was nor remarkable. The concentration of total lipid, the values of TBARS and total cholesterol was significantly decreased in the CGY group compared with control group, and the concentration of plasma HDL-cholesterol was not remarkable. The concentration of tryglycende in plasma showed a tendency to decreased. Conclusions : it is suggested that Cheongeumyeonsudan decreased the activities of free radical, the concentration of lipid in plasma and generate enzyme which form lipid peroxide.

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Effects of three different formulae of Gamisoyosan on lipid accumulation induced by oleic acid in HepG2 cells

  • Go, Hiroe;Ryuk, Jin Ah;Hwang, Joo Tae;Ko, Byoung Seob
    • Integrative Medicine Research
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    • v.6 no.4
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    • pp.395-403
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    • 2017
  • Background: Gamisoyosan (GSS) is an herbal formula which has been used to treat women's diseases for several hundred years in Korea. GSS is one of the three most common prescriptions among women and is used to treat menopausal symptoms. Fatty liver disease is also common in postmenopausal women and can precede more severe diseases, such as steatohepatitis. The present study compared the effects of GSS on fatty liver using three different formulae, Dongui-Bogam (KIOM A), Korean Pharmacopeia (KIOM B) and Korean National Health Insurance (KIOM C). Methods: In oleic acid-induced HepG2 fatty liver cells, cellular lipid accumulation, triglycerides and total cholesterol were measured after treatment with three GSS formulae and simvastatin as a positive control. To investigate the phytoestrogen activity of GSS, MCF-7 cells were treated with GSS, and hormone levels were quantified. Also, qualitative analysis was performed with UPLC. Results: All types of GSS decreased cellular lipid accumulation. KIOM A was slightly less effective than the other two GSS formulae. KIOM B and KIOM C decreased cellular triglycerides more effective than simvastatin, but KIOM A did not affect cellular triglycerides. Cellular total cholesterol was decreased by all GSS and simvastatin. GSS showed phytoestrogen activity in MCF-7 cells. From the UPLC analysis data, geniposide, paeoniflorin and glycyrrhizin were detected form three GSS formulae. Conclusion: These results suggest that all GSS formulae have a beneficial effect on fatty liver disease during menopause and that differences of formula have no effect on the efficacy of the prescription.

Correlations of Deficiency and Excess Patterns between Menstrual Symptoms and Whole Body Symptoms (월경통(月經痛) 증후(證候)와 전신 증후(全身 證候)의 허실(虛實) 상호 관련성 연구)

  • Hwang, Jae-Ho;Jeong, Hui-Jin;Lee, Geon-Seok;Yun, Young-Jin
    • The Journal of Korean Obstetrics and Gynecology
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    • v.25 no.1
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    • pp.47-55
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    • 2012
  • Purpose: Dysmenorrhea mostly depends on the causative factor, which usually falls under the categories of Deficiency and Excess pattern in traditional Oriental medical theories and diagnosis. Thus, we investigated menstruation symptom and sign related to dysmenorrhea and verified the validity of Deficiency and Excess pattern identification. Methods: We investigated menstruation symptom and sign related to dysmenorrhea in total 14 gynecology-medical books including the book ${\ll}$Exemplar Of Korean Medicine (Dongui Bogam)${\gg}$ and whole body symptom and sign identifying Deficiency and Excess pattern at the same time. A survey based on this investigation was carried out targeting women of childbearing age. Results: Total of 14 gynecology-medical books have mostly narrated pre-menstrual and mid & post-menstrual pelvic pain depending on the time of its manifestation for identifying Deficiency and Excess pattern. Dysmenorrhea in pre-menstrual period belonged to Excess pattern and dysmenorrhea in mid & post-menstrual period belonged to Deficiency pattern. Among a total of 343 women, 196 subjects suffered from dysmenorrhea. The number of dysmenorrhea in pre-menstrual period (Excess pattern) was 116 people and in mid & post-menstrual period (Deficiency pattern) was 80 people. Deficiency and Excess pattern of dysmenorrhea in menstrual period significantly correlated to Deficiency and Excess pattern of whole body symptom and sign in the statistics(P-value < 0.05). Conclusion: The results suggest that pre-menstrual and mid & post-menstrual pelvic pain depending on the time of its manifestation is preferentially utilized as symptom and sign related to dysmenorrhea identifying Deficiency and Excess pattern.

Correlations of Cold and Heat Pattern between Menstrual Symptoms and Whole Body Symptoms (월경통(月經痛) 증후(證候)와 전신(全身) 증후(證候)의 한열(寒熱) 상호 관련성 연구)

  • Hwang, Jae-Ho;Yun, Young-Jin
    • The Journal of Korean Obstetrics and Gynecology
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    • v.25 no.4
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    • pp.27-37
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    • 2012
  • Purpose: Dysmenorrhea is mostly depending on the causative factor, which usually falls under the categories of Cold and Heat pattern in traditional Oriental medical theories and diagnosis. Thus, we investigated menstruation symptom and sign related to dysmenorrhea and verified the validity of Cold and Heat pattern identification. Methods: We investigated menstruation symptom and sign related to dysmenorrhea in total 14 gynecology-medical books including ${\ll}$Exemplar Of Korean Medicine (Dongui Bogam)${\gg}$ and whole body symptom and sign identifying Cold and Heat pattern at the same time. A survey based on this investigation was carried out targeting women of childbearing age. Results: According to 14 gynecology-medical books, polymenorrhea is relevant to Heat pattern, oligomenorrhea to Cold pattern and darkness of menstrual blood is relevant to Heat pattern. Among the total of 343 womens, 196 subjects suffered from dysmenorrhea. The number of dysmenorrhea with polymenorrhea(Heat pattern) was 6 person, with oligomenorrhea(Cold pattern) was 27 person. And the number of dysmenorrhea with darkness of menstrual blood(Heat pattern) was 39 person. As the result of checking correlations of menstrual symptom scores and whole body symptom scores, there was no significance of Cold and Heat pattern between menstrual symptoms and whole body symptoms. Conclusions: The results suggest that the period of menstrual cycle and the color of menstrual blood provides some informations of Cold and Heat pattern identification. But considering with other whole body symptom and sign is needed for more precise result.

Up-and-Down Procedure(UDP) Determinations of Acute Oral Toxicity of LMK02-Jangwonhwan in SD Rats (Sprague-Dawley 랫드를 이용한 Up & Down 법 (UDP)에 의한 LMK02의 단회 경구투여 독성시험)

  • Kang, Hyung-Won;Kwon, Yeong-Mi;Lee, Sang-Won;Kim, Ji-Hwon;Lee, Hyo-Gyung;Jang, Hyun-Ho;Park, Bo-Ra;Lyu, Yeoung-Su
    • Journal of Oriental Neuropsychiatry
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    • v.21 no.3
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    • pp.87-93
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    • 2010
  • Objectives : The oriental medicine Jangwonhwan originally described in the Korean medical text, DonguiBogam(amnesia chapter). Recently, a modified formula of Jangwonhwan(LMK02-Jangwonhwan), was shown to reduce $\beta$-amyloid deposition in the brain of Tg-APPswe/PS1dE9 mouse model for Alzheimer's disease. This experiment aimed to investigate the acute oral toxicity of LMK02 in SD rats by up-and-down procedure determinations. Methods : Quality control of tablet form of LMK02 was established by estimating indicative components, Ginsenoside Rg3 of Red Ginseng and Decursin of Angelicagigas Nakai. The toxicity of LMK02 was investigated in 6 week old, specific pathogen free(SPF), Sprageu-Dawley rats. 3 female rats received 5,000 mg/10 ml/kg of test substance and their death rate, clinical sings, weight changes and autopsy findings had been observed for 2 weeks. Results : Any specific symptoms or death were resulted in this experiment. No significant changes in rats' weight. No significant differences in atopsy. Conclusions : The minimum lethal dose(MLD) of LMK02 for female Sprauge-Dawley rats were more than 5,000mg/kg in this experiment.