• Title, Summary, Keyword: D-loop

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Stress Analysis of IPS Lower bracket

  • Lee, J.M.;Park, K.N.;Chi, D.Y.;Park, S.K.;Sim, B.S.;Lee, H.H.;Ahn, S.H.;Lee, C.Y.;Kim, H.R.
    • Proceedings of the Korean Nuclear Society Conference
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    • pp.703-704
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    • 2005
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Identification of Certain Sequences in the 3rd Cytoplasmic Loop of$D_4$ Dopamine Receptor that Suppress the Bacterial Expression

  • Cheong, Ji-Sook;Kim, Ae-Young;Kim, Kyeong-Man
    • Archives of Pharmacal Research
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    • v.19 no.4
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    • pp.275-279
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    • 1996
  • To study the functional roles of dopamine receptors, we decided to raise antibodies against these proteins. To make antigen, we expressed the whole 3rd cytoplasmic loop of dopamine receptors in a fusion protein with glutathione-S-transferase (GST). $For D_2\; and\; D_3$ receptors, it was successful to express and purify fusion proteins for the whole 3rd cytoplasmic loops. However, we could not express the fusion protein for the whole 3rd cytoplasmic loop of $D_4$ dopamine receptor in the bacteria. To study the causes that prevent the bacterial expression of the GST-fusion protein of the 3rd cytoplasmic loop of $D_4$ dopamine receptor, we conducted more detailed studies on $D_4$ dopamine receptor. To locate the region which prevents bacterial expression, we made sequential constructs in the 3rd cytoplasmic loop decreasing the size step by step, and confirmed their expressions in the SDS PAGE. It was found that certain regions of 3rd cytoplasmic loop of $D_4$ dopamine receptor, located in N-terminal side of the 3rd cytoplasmic loop of $D_4$ dopamine receptor suppress the bacterial expression of fusion protein.

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Improved Transmitter Power Efficiency using Cartesian Feedback Loop Chip

  • Chong, Young-Jun;Lee, Il-Kyoo;Oh, Seung-Hyeub
    • Journal of electromagnetic engineering and science
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    • v.2 no.2
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    • pp.93-99
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    • 2002
  • The Cartesian loop chip which is one of key devices in narrow-band Walky-Talky transmitter using RZ-SSB modulation method was designed and implemented with 0.35 Um CMOS technology. The reduced size and low cost of transmitter were available by the use of direct-conversion and Cartesian loop chip, which improved the power efficiency and linearity of transmitting path. In addition, low power operation was possible through CMOS technology. The performance test results of transmitter showed -23 dBc improvement of IMD level and -30 dEc below suppression of SSB characteristic in the operation of Cartesian loop chip (closed-loop). At that time, the transmitting power was about 37 dBm (5 W). The main parameters to improve the transmitting characteristic and to compensate the distortion in feed back loop such as DC-offset, loop gain and phase value are interfaced with notebook PC to be controlled with S/W.

Extended Loop Antenna for the Mobile Handset (휴대 단말기용 연장 루프안테나)

  • Son, Taeho;Ryu, Hwang
    • The Journal of The Korea Institute of Intelligent Transport Systems
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    • v.12 no.2
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    • pp.30-37
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    • 2013
  • An extended loop antenna, to be continued BLA(Branch Loop Antenna) in the previous volume, for the mobile handset is designed in this paper. It's introduced an ELA(Extended Loop Antenna) that is added extended loops to rectangular loop, and verified antenna performances for applying to mobile handset. Extended loops are located upside, left and right side of rectangular loop, and low resonance is obtained by the length of line. Multiple resonances are established by the extended loops, and obtained the desired service bands by the connection points and lengths. By the implementation and measurement for the multiband ELA, it's showed -3.0~-1.46dBi average gains with 50.15~71.41% efficiencies at CDMA/GSM frequency band, and -8.28~-1.7dBi average gains with 14.87~67.68% efficiencies at DCS/USPCS/WCDMA frequency band.

Novel Mutations in the Displacement Loop of Mitochondrial DNA are Associated with Acute Lymphoblastic Leukemia: A Genetic Sequencing Study

  • Yacoub, Haitham Ahmed;Mahmoud, Wael Mahmoud;El-Baz, Hatim Alaa El-Din;Eid, Ola Mohamed;ELfayoumi, Refaat Ibrahim;Elhamidy, Salem Mohamed;Mahmoud, Maged M.
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.21
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    • pp.9283-9289
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    • 2014
  • Background: Acute lymphoblastic leukemia (ALL) is the most common cancer diagnosed in children and represents approximately 25% of cancer diagnoses among those younger than 15 years of age. Materials and Methods: This study investigated alterations in the displacement loop (d-loop) region of mitochondrial DNA (mtDNA) as a risk factor and diagnostic biomarker for early detection and diagnosis of acute lymphoblastic leukemia. Using mtDNA from 23 subjects diagnosed with acute lymphoblastic leukemia, the first 450 bp of the d-loop region were amplified and successfully sequenced. Results: This revealed 132 mutations at 25 positions in this region, with a mean of 6 alterations per subject. The d-loop alterations in mtDNA in subjects were all identified as single nucleotide polymorphisms in a homoplasmic distribution pattern. Mutant alleles were observed in all subjects with individual frequency rates of up to 95%. Thirteen mutant alleles in the d-loop region of mtDNA occurred with a high frequency. Novel alleles and locations were also identified in the d-loop of mtDNA as follows: 89 G insertions (40%), 95 G insertions (13%), 182 C/T substitutions (5%), 308 C insertions (19%), and 311 C insertions (80%). The findings of this study need to be replicated to be confirmed. Conclusions: Further investigation of the relationship between mutations in mitochondrial d-loop genes and incidence of acute lymphoblastic leukemia is recommended.

Design and Implementation of a Linearizer Using the Feedforward Loop without Delay Lines (지연 선로가 없는 Feedforward Loop를 이용한 선형화기의 설계 및 제작)

  • 정승환;조경준;김완종;안창엽;김종헌
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.11 no.1
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    • pp.116-123
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    • 2000
  • This paper presents a linearizer using the feedforward loop which can be applied to PCS base-station applications. This linearizer used a IM amplifier and an auxiliary amplifier in order to remove delay lines used in the predistortor using the feedforward technique. The delay line in error loop is changed by the main power amplifier(PA) and the error amplifier is utilized to amplify the error signal which fed to the output of main amplifier. The linearizer was simulated by HP ADS ver 1.1 and fabricated on GML 1000 with thickness of 0.8 mm and dielectric constant of 3.2. Two-tone signals at 1.85 GHz and 1.851 GHz with -7dBm/tone from synthesizers are injected into the main PA. The main PA with a 27 dB gain and a $P_{1dB}$ of 29 dBm(two-tone) was utilized. The reduction of intermodulation distortion (IMD) is around 17 dB.

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