• Title, Summary, Keyword: Cervix Cancer

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Single Life Time Cytological Screening in High Risk Women as an Economical and Feasible Approach to Control Cervical Cancer in Developing Countries Like India

  • Misra, Jata Shankar;Srivastava, Anand Narain;Das, Vinita
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.3
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    • pp.859-862
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    • 2015
  • In view of funding crunches and inadequate manpower in cytology in developing countries like India, single lifetime screening for cervical cancer has been suggested. In this study, an attempt was made to cscreening to make it more effective for early detection. Cytological data were derived from the ongoing routine cervical cytology screening program for women attending Gynaecology Out Patient Department of Queen Mary's Hospital of K.G.Medical University, Lucknow, India during a span of 35 years (April 1971 - December 2005). Cervical smears in a total of 38,256 women were cytologically evaluated. The frequencies of squamous intraepithelial lesions of cervix (SIL) and carcinoma cervix were found to be 7.0% and 0.6%, respectively, in the series. Predisposing factors related to cervical carcinogenesis were analyzed in detail to establish the most vulnerable groups of women for single life time screening. The incidence of SIL and carcinoma cervix was found to be maximal in women above the age of 40 years irrespective of parity and in multiparous women (with three or more children) irrespective of age. The incidence of cervical cytopathologies was significantly higher in symptomatic women, the frequency of SIL being alarmingly higher in women complaining of contact bleeding and that of carcinoma cervix in older women with postmenopausal bleeding. It is consequently felt that single life time screening must include the three groups of women delineated above. Such selective screening appears to be the most economical, cost effective and feasible approach to affordably control the menace of cervical cancer in developing countries like India.

Nationwide Incidence Estimation of Uterine Cervix Cancer among Korean Women (한국 여성에서의 자궁경부암 발생률)

  • Park, Byung-Joo;Lee, Moo-Song;Ahn, Yoon-Ok;Choi, Young-Min;Ju, Yeong-Su;Yoo, Keun-Young;Kim, Hun;Yew, Ha-Seung;Park, Tae-Soo
    • Journal of Preventive Medicine and Public Health
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    • v.29 no.4
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    • pp.843-851
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    • 1996
  • To estimate the incidence of uterine cervix cancer among Korean women, we have conducted a study using the claim data on the beneficiaries of Korea Medical Insurance Corporation (KMIC). All medical records of the potential cases with diagnosis of ICD-9 180, 181, 182, 199, 219, 233 in the claims sent by medical care institutions in the whole country to the KMIC from January 1988 to December 1989, were abstracted and Gynecology specialist reviewed the records to identify the new cases of uterine cervix cancer among the potential cases during the corresponding period. Using these data, the incidence of uterine cervix cancer among Korean women was estimated as of July 1, 1988 to June 30, 1989. The crude rate was estimated to be 17.34(95% CI: $16.76\sim17.92$) per 100,000 and the cumulative rates for the ages $0\sim64\;and\;0\sim74$ were 1.7% and 2.2%, respectively. The age-adjusted rate for the world population was 19.93 per 100,000 which was higher than those of other Asian countries including China and Japan in $1983\sim1987$. The truncated rate for ages $35\sim64$ was 52.05 per 100,000 which was one of the highest in the world. With increasing age, the incidence rate increased to 78.11 per 100,000 in women aged $55\sim59$ years, then it decreased in the older groups. This finding suggests that detecting rate of uterine cervix cancer may decrease in women aged 60 years or older due to inadequate medical care seeking behavior. In the geographical area, the SIR of Jeju province was significantly low but it might be due to statistical unstability by small case numbers.

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Medical-and-Psychosocial Factors Influencing on the Quality of Life in Patients with Cervix Cancer (자궁경부암환자의 삶의 질에 영향을 미치는 치료관련 및 심리사회적 요인)

  • Chun, Mi-Son;Lee, Eun-Hyun;Moon, Seong-Mi;Kang, Seung-Hee;Ryu, Hee-Sug
    • Radiation Oncology Journal
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    • v.23 no.4
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    • pp.201-210
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    • 2005
  • Purpose: Quality of life in patients with cancer may be influenced by various kinds of variables, such as personal, environmental, and medical factors. The purpose of this study was to identity the influencing factors on the quality of life in patients with cancer. Materials and Methods: One hundred and forty seven patients, who were taking medical therapy or following up after surgery for cervix cancer, participated in the present study. Quality of life, medical variables (cancer stage, types of treatment, follow-up status, and symptom distress), and psychosocial variables (mood disturbance, orientation to life, and social support) were measured. The obtained data were computed using multiple regression analyses. Results: The medical-and-psychosocial variables explained 63.3% of the total variance in the quality of life ($R^2=0.633$ F:16.959, p=.000). Cancer stage, symptom distress, mood disturbance, social support(family), and optimistic orientation to life were significant factors influencing on the quality of life in patients with cervix cancer. Conclusion: An integrative care program which includes medical - and - psychosocial characteristics of patients is essential to improve quality of life in patients with cervix cancer.

Reasons for Variation in Sensitivity and Specificity of Visual Inspection with Acetic Acid (VIA) for the Detection of Pre-Cancer and Cancer Lesions of Uterine Cervix

  • Parashari, Aditya;Singh, Veena
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.12
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    • pp.7761-7762
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    • 2013
  • Alternative strategies such as visual inspection of cervix with acetic acid, are real time, economical and easily implemented methods for cervical cancer screening. However, variable sensitivity and specificity have been observed in various community based studies. The possible reasons could include variation in man power training, light source used for visualization, and preparation of diluted (4-5%) acetic acid and its storage. A standardized protocol for training, teaching material (easy to understand in the local language) for trainees, supervision and reinforcement by intermittent and supplementary training to check the quality of their observation, a standard protocol for preparation dilute acetic acid and its storage and a standard good light source (equivalent to day light) are needed to minimize the variation in sensitivity and specificity of VIA in community settings.

A Study on Nausea & Vomiting, Anorexia and Food intake in Cancer Patients undergoing Chemotherapy Overtime - Comparison between Cervix Cancer and Stomach Cancer - (항암화학요법을 받는 암환자의 시기별 오심과 구토, 식욕부진 및 음식섭취에 관한 연구 - 자궁암 환자와 위암 환자의 비교 -)

  • Yu, Seong-Mi;Gu, Mee-Ock
    • Korean Journal of Adult Nursing
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    • v.15 no.4
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    • pp.573-584
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    • 2003
  • Purpose: This study was conducted to investigate the level of nausea & vomiting, anorexia and food intake during the periods of chemotherapy and 14 days after discharge. Method: The subjects were 40 cancer patients(cervix cancer : 20 patients, stomach cancer: 20 patients) who had chemotherapy with Cisplatin & 5-Fu. Data were analyzed by mean & standard deviation, ANCOVA. Result: 1. The severity of nausea & vomiting with anorexia in cancer patients receiving chemotherapy was the highest at the 3rd day and then it gradually decreased. At the 14th day after discharge, nausea & vomiting with anorexia still remained with very low levels. 2. The amount of food intake was the lowest on the 3rd day and then gradually increased. However, it was 53.3-72.5% of the ordinary food intake on the 14th day after discharge. Calorie intake was 625.31 Kcal on the 3rd day and 1130.92 Kcal on the 7th day after discharge. 3. There were no significant differences in nausea & vomiting, anorexia, food intake, calory intake between those with cervix cancer and stomach cancer. Conclusion: In cancer patients nausea & vomiting and anorexia were severe and food intake was very poor during chemotherapy but afterwards they were gradually improved, but were not completely recovered on the 14th day after discharge. Therefore the nursing intervention regarding the increase of food intake was necessary during chemotherapy and after discharge.

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Changes in the Distribution of Cancer Incidence in Nepal from 2003 to 2013

  • Poudel, Krishna Kanta;Huang, Zhibi;Neupane, Prakash Raj;Steel, Roberta
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.10
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    • pp.4775-4782
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    • 2016
  • Background: Cancer incidence data are vital for cancer control planning in any nation. This retrospective study was conducted to compare the cancer incidence of all sites between the first cancer registry report and the most recent example in Nepal. Material and Methods: The cases in the first (2003) and latest (2013) national cancer registry reports, accumulated by all the hospital based cancer registries in Nepal were taken for the research. The frequencies, crude incidences and age specific incidences (per 100,000) of the five major cancers were calculated for both males and females. Result: The most common cancer type for males in both years 2003 and 2013 was lung. Stomach was the third most common cancer in 2003 while it was the second in 2013. Similarly, the first four major cancers (cervix, breast, lung and ovary) did not change between 2003 and 2013 in females. The total cancer incidence rate increased from 12.8 in 2003 to 30.4 per 100,000 in 2013 for males and from 15.1 to 33.3 in females. Conclusion: The most common cancers in males in 2003 and 2013 were the bronchus and lung. Similarly, the most common cancer in females was cervix at both time points. The cancer incidence rate in females was higher than in males both in 2003 and 2013.

A Study on Specificity of Cancer Incidence in Daegu-Kyungbuk Area (일부 지역의 암발생 특성에 관한 조사연구)

  • 김진모;민경진
    • Korean Journal of Health Education and Promotion
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    • v.6 no.1
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    • pp.60-65
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    • 1989
  • A statistical analysis was made on 15,971 surgically operated patients at D-Medical Center in the year of 1978 and 1988. 1,416 cancer patients among them were classified by sex, age, and malignant tumor site. The obtained results indicated that trend of male cancer was generally similar to the results of nation wide study. But, specific phenomenon was found in the case of female cancer in Daegu-Kyungbuk area. Among females the frequency rank was uterine cervix (35.77%), breast (17.97%), stomach (11.65%) in 1988. The frequency of uterine cervix was higher than other area. Breast cancer was highly ranked tumor compare with other area, and its age distribution also appeared in much younger decade.

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Lack of Participation of the GSTM1 Polymorphism in Cervical Cancer Development in Northeast Thailand

  • Natphopsuk, Sitakan;Settheetham-Ishida, Wannapa;Settheetham, Dariwan;Ishida, Takafumi
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.5
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    • pp.1935-1937
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    • 2015
  • The potential association between the GSTM1 deletion polymorphism and risk of cervical cancer was investigated in Northeastern Thailand. DNA was extracted from buffy coat specimens of 198 patients with squamous cell carcinoma of the cervix and 198 age-matched healthy controls. Genotyping of the GSTM1 was conducted by using two PCR methods, a short- and a long-PCR. Distribution of the GSTM1 genotypes in between the cases and the controls was not significantly different (p>0.5 by ${\chi}^2$ test). The results suggest that the GSTM1 deletion polymorphism is not a risk factor for squamous cell carcinoma of the cervix in the northeast Thai women.

Whole Genome Analysis of Human Papillomavirus Genotype 11 from Cervix, Larynx and Lung

  • Chansaenroj, Jira;Theamboonlers, Apiradee;Junyangdikul, Pairoj;Supiyaphan, Pakpoom;Poovorawan, Yong
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.6
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    • pp.2619-2623
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    • 2012
  • The prevalence of human papillomavirus genotypes differs in various target organs. HPV16 is the most prevalent genotype in the cervix while genotypes 6 and 11 are highly prevalent in skin and aero-digestive tract infections. In this study HPV11 positive specimens were selected from cervix, larynx and lung biopsy tissue to analyze the whole genome by PCR and direct sequencing. Five HPV11 whole genomes were characterized, consisting of two cervical specimens, two laryngeal specimens and one lung specimen. The results showed high homology of HPV11 in these organs. Phylogenetic analysis showed that all HPV11 derived from various organs belonged to the same lineage. Molecular characterization and functional studies can further our understanding of virulence, expression or transmission. Additional studies on functional protein expression at different organ sites will also contribute to our knowledge of HPV infection in various organs.

Breast, Cervix and Colorectal Cancer Knowledge among Nurses in Turkey

  • Andsoy, Isil Isik;Gul, Asiye
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.5
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    • pp.2267-2272
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    • 2014
  • Background: Cancer is one of the most common causes of death in Turkey. Nurses are essential providers of preventive care for patients, especially breast, cervical and colorectal cancer screening as part of routine preventive practice. The aim of this study was to assess knowledge of these cancers among nurses in Karabuk State Hospital. Materials and Methods: This cross-sectional and descriptive study was performed from April 1 to July 30, 2013. The study sample consisted of 226 nurses working in Karabuk State Hospital. Results: Mean age of the nurses was $32.07{\pm}8.39$. 62.4% of nurses practiced breast self examination when they remembered it, while 39.8% of them did not take a Pap smear test since they did not think it was necessary. 64.2% of nurses would like to receive information about cancer and screening tests. Majority of them had given true answers to questions on breast, cervical and colorectal cancer. There were significant relationships between cancer knowledge scores and marital status, working experience, and level of education. Conclusions: Nurses possess adequate knowledge about breast cancer but they need more information on cancer risk estimation. Awareness may be raised in nurses by establishing continuing education programs regarding the risk factors, symptoms, protection methods, early diagnosis, and scanning of breast, cervix and colon cancers.