• Title, Summary, Keyword: Breast neoplasm

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Fine Needle Aspiration Cytology of Tubulolobular Carcinoma of the Breast - A Case Report - (관상소엽암종의 세침흡인 세포학적 소견 - 1 예 보고 -)

  • Lee, Ji-Shin;Kim, Young-Bog
    • The Korean Journal of Cytopathology
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    • v.13 no.2
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    • pp.84-87
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    • 2002
  • Tubulolobular carcinoma is a tumor of the breast that shares histoiogic features of both tubular and lobular carcinoma of the breast. The cytologic features of this neoplasm have not been reported in Korea. We described a case of tubulolobular carcinoma diagnosed by fine needle aspiration cytology in a 46-year-old female. The tumor contained several cytologic features of both tubular and lobuar carcinoma, including tubular structures, single filing of cells, intracytoplasmic vacuoles, and low nuclear grade.

Benefits and Harms of Phytoestrogen Consumption in Breast Cancer Survivors

  • Alipour, Sadaf;Jafari-Adli, Shahrzad;Eskandari, Amirhossein
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.8
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    • pp.3091-3096
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    • 2015
  • Worldwide, breast cancer is the most common malignant neoplasm and the second most common cause of cancer death in women. This malignancy is recognized to be estrogen-dependent and due to this feature, hormone replacement therapy is regarded as potentially dangerous in breast cancer survivors who seek relief of their menopausal symptoms. Whereas hot flashes are detected in nearly half of postmenopausal women with a relatively high frequency and severity, botanic sources of estrogens have been proposed as an alternative treatment. Nevertheless, estrogenic properties of these compounds suggest possibility of stimulating cancer recurrence or worsening prognosis in survivors. As well, effects in improving vasomotor climacteric changes is controversial. Many studies have considered the subject, some focusing on efficacy of phytoestrogens for control of menopausal symptoms, and others discussing effects of these compounds on breast cancer outcome in terms of survival or recurrence. The present article is a concise review of the effects of consumption of phytoestrogens on menopausal symptoms, namely hot flashes, and breast cancer recurrence and mortality in survivors of the disease. Overall, the major part of the current existing literature is in favor of positive effects of phytoestrogens on breast cancer prognosis, but the efficacy on menopausal symptoms is probably minimal at the best.

Fine Needle Aspiration Cytology of Primay Malignant Lymphoma of the Breast - A Case Report - (유방에 발견한 원발신 악성 림프종의 세침흡인 세포학적 소견 - 1예 보고 -)

  • Kim, Hyun-Joong;Lee, Kyung-Hwa;Kim, Jo-Heon;Shim, Min-Keun;Choi, Chan;Lee, Ji-Shin
    • The Korean Journal of Cytopathology
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    • v.15 no.2
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    • pp.112-115
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    • 2004
  • Lymphoproliferative disorders, manifesting either as a primary lesion or as part of a generalized process, rarely involve the breast. The primary malignant lymphoma of the breast is rare. The cytologic features of this neoplasm have not been reported in Korea thus far. We described a case of primary malignant lymphoma of the breast, as diagnosed by fine needle aspiration cytology (FNAC) in an 84-year-old female. FNAC smears showed high cellularity. The main cytologic feature observed was a carpeting of monotonous, atypical, enlarged lymphoid cells. These lymphocytes showed relatively round elliptical nuclei with some indentation. One or more prominent nucleoli were seen. Biopy from the breast mass revealed diagnostic features of non-Hodgkin's lymphoma, diffuse large B-cell type.

A Case Report of Male Occult Breast Cancer Manifested as Superior Vena Cava Syndrome (상대 정맥 증후군으로 발현된 남성 잠재성 유방암의 증례 보고)

  • Kang, Hyein;Ha, Su Min;Ahn, Hye Shin;Kim, Hee Sung;Kim, Hee-Jun
    • Journal of the Korean Society of Radiology
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    • v.79 no.4
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    • pp.204-207
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    • 2018
  • Occult breast cancer (OBC) is an asymptomatic condition. We report a case of OBC in a 72-year-old male patient who presented with severe dyspnea and upper extremity swelling. Computed tomography scan showed multiple lymph node enlargements in the supraclavicular and infraclavicular areas, and ultrasound scan showed multiple axillary lymph node enlargements. Based on the radiological findings, clinicians suspected lymphoma or disseminated metastasis from unknown primary malignancies. However, the axillary biopsy specimen revealed invasive breast cancer with hormonal receptor positivity.

Advances in Optimal Detection of Cancer by Image Processing; Experience with Lung and Breast Cancers

  • Mohammadzadeh, Zeinab;Safdari, Reza;Ghazisaeidi, Marjan;Davoodi, Somayeh;Azadmanjir, Zahra
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.14
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    • pp.5613-5618
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    • 2015
  • Clinicians should looking for techniques that helps to early diagnosis of cancer, because early cancer detection is critical to increase survival and cost effectiveness of treatment, and as a result decrease mortality rate. Medical images are the most important tools to provide assistance. However, medical images have some limitations for optimal detection of some neoplasias, originating either from the imaging techniques themselves, or from human visual or intellectual capacity. Image processing techniques are allowing earlier detection of abnormalities and treatment monitoring. Because the time is a very important factor in cancer treatment, especially in cancers such as the lung and breast, imaging techniques are used to accelerate diagnosis more than with other cancers. In this paper, we outline experience in use of image processing techniques for lung and breast cancer diagnosis. Looking at the experience gained will help specialists to choose the appropriate technique for optimization of diagnosis through medical imaging.

Effects of Semen Sinapsis Albae Acupressure on Fatigue and Sleep Related Chemotherapy in Patients with Breast Cancer (백개자 경혈 지압이 항암화학요법을 받는 유방암 환자의 피로 및 수면에 미치는 효과)

  • Kang, Mi Ae;Kim, Yeong Kyeong;Shin, Jung Soon;Yeo, Hyung Nam
    • Journal of Korean Clinical Nursing Research
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    • v.21 no.2
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    • pp.180-187
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    • 2015
  • Purpose: This study was done to identify the effects of semen sinapsis albae acupressure on fatigue and sleep among patients undergoing chemotherapy for breast neoplasms. Methods: The design was a nonequivalent control group nonsynchronized design. Participants were 46 hospitalized patients (23 in the experimental group and 23 in the control group) who were undergoing chemotherapy during November and December 2014. The experimental group underwent routine chemotherapy nursing care and at the same time received acupressure on the spots of Zoksamli, Samumgyo and Shinmun. The control group underwent routine chemotherapy nursing care. The data were analyzed using test and t-test with the SPSS 21.0 program. Results: The level of fatigue in the experimental group was lower than in the control group (t=5.82, p<.001). The level of sleep in the experimental group was higher than in the control group (t=-5.16, p<.001). Conclusion: The findings of the study indicate that acupressure is an effective nursing intervention to decrease fatigue and increase sleep in patients with breast neoplasm undergoing chemotherapy.

Imperfect Correlation of Mammographic and Clinical Breast Tissue Density

  • Alipour, Sadaf;Bayani, Leila;Saberi, Azin;Alikhassi, Afsaneh;Hosseini, Ladan;Eslami, Bita
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.6
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    • pp.3685-3688
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    • 2013
  • Background: Clinicians determine degree of mammographic density based on tissue firmness on breast examination. The study aimed to compare breast density in mammography and clinical breast examination. Materials and Methods: Six-hundred sixty three women 40 years of age or older were studied. The breast exam density was graded from 1 to 4 by two expert surgeons and the mammographic parenchymal density by two expert radiologists. Then for practical reasons, grades 1 and 2 were considered as low-density and grades 3 and 4 as high-density. Results: High and low densities were detected in 84.5% and 15.5% of clinical breast examinations and 59.7% and 40.3% of mammographies, respectively. The statistical analysis showed a significant difference between the breast tissue densities in breast examination with those in mammography. Conclusions: A clinically dense breast does not necessarily imply a dense mammographic picture.

Lobular Breast Carcinoma Metastasis to the Thyroid Gland: Case Report and Literature Review

  • Bourcier, Kevin;Fermeaux, Veronique;Leobon, Sophie;Deluche, Elise
    • Journal of Breast Cancer
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    • v.21 no.4
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    • pp.463-467
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    • 2018
  • Metastasis from primary cancer to the thyroid is uncommon in breast cancer. Here we present a case of lobular breast carcinoma that metastasized to the thyroid. A 54-year-old woman without symptoms was admitted to our institution for staging of the lymph node above the left clavicle. An $^{18}F$-fluoro-deoxy-D-glucose positron emission tomography scan was performed for staging, and low uptakes were observed in the left supraclavicular and cervical lymph nodes. High uptake was seen in the posterior and lower left lobe of the thyroid. Histologic findings indicated lobular breast carcinoma (positive GATA3, loss of E-cadherin expression) metastatic to the thyroid with a luminal profile. Immunohistochemical analysis was negative for primary thyroid or parathyroid carcinoma. To our knowledge, this is the first report of a patient presenting a metastatic invasive lobular carcinoma in the thyroid and lymph nodes without a prior diagnosis of breast cancer.

A Case of Breast Cancer Brain Metastasis with a 16-Year Time Interval without Evidence of Cancer Recurrence

  • Yamada, Shoko Merrit;Tomita, Yusuke;Shibui, Soichiro;Kurokawa, Takashi;Baba, Yasuhisa
    • Journal of Breast Cancer
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    • v.20 no.2
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    • pp.212-216
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    • 2017
  • The median time of brain metastasis from the diagnosis of breast cancer is approximately 3 years. In this case report, a 69-year-old woman demonstrated cerebellar ataxia. Brain magnetic resonance imaging revealed enhanced lesions in bilateral cerebellar hemispheres. She had undergone surgery, radiation, and chemotherapy for uterine and breast cancer 24 years prior and 16 years prior, respectively. Although she had not received any anticancer treatment for 10 years, no recurrences were identified using whole body scans. A partial tumor resection was performed and the histological diagnosis was an adenocarcinoma from breast cancer. As no extracranial lesions were found, gamma-knife irradiation was performed, without additional systemic chemotherapy. One month posttreatment, the tumors dramatically reduced in size and the patient completely recovered from cerebellar ataxia. Systemic chemotherapy is not always required for brain metastasis from breast cancer with a long interval period, as long as no evidence of extracranial recurrence is detected.

The Shoulder Pain due to Metastatic Breast Cancer -A Case Report-

  • Kim, Sae-Young;Jung, Min-Woo;Kim, Jin-Mo
    • The Korean Journal of Pain
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    • v.24 no.2
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    • pp.119-122
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    • 2011
  • A rotator cuff tear causes shoulder pain and limits movement of the shoulder joint. A chronic degenerative change or impingement is the reason for a rotator cuff tear. Diagnosis is made based on medical history and, physical and radiological examinations. Other causes of shoulder pain include calcific tendinitis, degenerative arthropathy, joint dislocation, fracture, and primary or metastatic neoplasm. However, metastatic cancer in the shoulder joint is difficult to diagnosis. We experienced a case in which a 46-year-old female patient complained of left shoulder pain and limited joint mobility, and these symptoms were due to metastatic breast cancer in the shoulder.