• Title, Summary, Keyword: Blood Parameters

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Relation between Obesity Pattern Identification and Metabolic Parameters in Overweight and Obese Women (과체중 및 비만 여성에서 한방비만변증에 따른 체성분 및 대사관련 지표의 상관성)

  • Song, Miyoung;Kim, Hojun;Lee, Myeong-Jong
    • Journal of Korean Medicine for Obesity Research
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    • v.14 no.1
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    • pp.24-28
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    • 2014
  • Objectives: We conducted this study to analysis obesity pattern and obesity related blood parameters. Methods: A total of 64 overweight and obese (body mass index [BMI] ${\geq}23cm/kg^2$) women who had no other disease was recruited. Body composition and obesity related blood parameters were measured. Also subjects were given and filled out the Obesity pattern identification questionnaire. We analyzed the differences of body composition and blood parameters and measured correlations of BMI and blood parameters in each obesity pattern. Results: The distribution of obesity pattern was liver depression (35.6%), food accumulation (47.5%) and deficiency (pi and yang deficiency, 22.0%), in order. There were no significant differences age, body composition and obesity related blood parameters between obesity patterns. BMI and obesity related blood parameters, however, showed significant correlations depending on obesity patterns. Conclusions: We concluded that correlations between BMI and obesity related blood parameters were differed depending on obesity patterns.

A Survey on Blood Pressure and Hematic Parameters During Pregnancy by Women of Premature Delivery (미숙아를 출산한 산모의 임신 중 혈압과 혈액지표 조사)

  • Lee, Seung-Lim;Chang, Yu-Kyung
    • Korean Journal of Community Nutrition
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    • v.13 no.6
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    • pp.903-911
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    • 2008
  • The purpose of this study is to provide basic data for preventing preterm delivery in the aspects of blood pressure and hematic parameters. The blood pressure, hematic parameters, relationship between hematic parameters and nutritional intakes and pregnancy outcomes were compared between a preterm delivery group and a normal term delivery group. The results obtained are summarized as follows. Diastolic blood pressure was statistically higher in the preterm delivery group. White blood cells (p < 0.005) and alanine amino transferase (p < 0.05) of 3rd trimester in pregnancy were statistically higher in the preterm delivery group. Alkaline phosphatase (p < 0.0001) and lactate dehydrogenase (p < 0.05) were statistically lower in the preterm delivery group. Inverse relationships between niacin, vitamin B6 and zinc intakes and bilirubin (p < 0.05) were shown. Vitamin A intakes (p < 0.05) were significantly negatively correlated with blood protein, but zinc intakes (p < 0.05) were significantly positively correlated with blood protein. Vitamin B6 intakes (p < 0.05) were significantly negatively correlated with blood albumin. Calcium intakes (p < 0.005) and iron intakes (p < 0.05) were significantly positively correlated with blood lactate dehydrogenase. Also, vitamin A intakes (p < 0.05) were significantly positively correlated with blood glucose. Normal spontaneous vaginal delivery (p < 0.005) was statistically lower in the preterm delivery group. Birth weight (p < 0.0001) and birth length (p < 0.005) of the neonates were all statistically lower in the preterm delivery group.

A Genome-wide Association Study of Copy Number Variation in Hematological Parameters in the Korean Population

  • Kim, Ka-Kyung;Cho, Yoon-Shin;Cho, Nam-H.;Shin, Chol;Kim, Jong-Won
    • Genomics & Informatics
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    • v.8 no.3
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    • pp.122-130
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    • 2010
  • Abnormal hematological values are associated with various disorders including cancer and cardiovascular, metabolic, infectious, and immune diseases. We report the copy number variations (CNVs) in clinically relevant hematological parameters, including hemoglobin level, red and white blood cell counts, platelet counts, and red blood cell (RBC) volume. We describe CNVs in several loci associated with these hematological parameters in 8,842 samples from Korean population-based studies. The data that we evaluated included four RBC parameters, one platelet parameter, and one associated with total white blood cell (WBC) count, exceeding the genome-wide significance. We show that CNVs in hematological parameters are associated with some loci, different from previously associated loci reported in single nucleotide polymorphism (SNP) association studies.

Dynamics of Facial Subcutaneous Blood Flow Recovery in Post-stress Period

  • Sohn, Jin-Hun;Estate M. Sokhadze;Lee, Kyung-Hwa;Lee, Jong-Mi;Park, Mi-Kyung;Park, Ji-Yeon
    • Proceedings of the Korean Society for Emotion and Sensibility Conference
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    • pp.62-68
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    • 2000
  • The aim of the study was to compare effects of music and white noise on the recovery of facial blood flow parameters after stressful visual stimulation. Twenty-nine subjects participated in the experiment. Three visual stimulation sessions with aversive slides (the IAPS, disgust category) were followed by subjectively "pleasant" (in the first session), "sad" music (in the second ), and white noise (in the third ). Order of sessions was counterbalanced. Blood flow parameters (peak blood flow, blood flow velocity, blood volume) were recorded by Laser Doppler single-crystal system (LASERFLO BPM 403A) interfaced through BIOPAC 100WS with AcqKnowledge software (v.3.5) and analyzed in off-line mode. Aversive visual stimulation itself decreased blood flow and velocity in all 3 sessions. Both "pleasant" and "sad" music led to the restoration of baseline levels in all blood flow parameters, while noise did not enhance recovery process. Music on post-stress recovery had significant change in peak blood flow and blood flow velocity, but not in blood volume measures. Pleasant music had bigger effects on post-stress recovery in peak blood flow and flow velocity than white noise. It reveals that music exerted positive modulatory effects on facial vascular activity measures during recovery from negative emotional state elicited by stressful slides. Results partially support the undoing hypothesis of Levenson (1994), which states that positive emotions may facilitate process of recovery from negative emotions.

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Evaluation of valid time for analysis of complete blood cell in pig blood using the Hemavet 950FS (자동혈구분석기 Hemavet 950FS를 이용한 돼지 혈액 내 혈구분석의 유효시간 평가)

  • Kim, Ki-Hyun;Kim, Kwang-Sik;Kim, Doo-Wan;Sa, Soo-Jin;Kim, Young-Hwa
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.18 no.1
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    • pp.194-201
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    • 2017
  • This study was conducted to determine the valid time for accurate detection of complete blood cell count (CBC) in pig blood using an automatic blood corpuscle analyzer (Hemavet 950FS). Blood samples were collected from 34 pigs (Duroc) with a 60 kg (${\pm}3.5$) body weight. Ten specimens with CBC parameters in normal range and with no hemolysis were selected among 34 samples and used in this study. Regarding leukocytes parameters, white blood cell (WBC), neutrophil (NE), and lymphocyte (LY) counts showed a low daily variation (coefficient of variation, CV), whereas monocyte (MO), eosinophil (EO), and basophil (BA) CVs were significantly high (19.7, 56.9, and 53.3%, respectively). On the other hand, all parameters of erythrocytes and thrombocytes showed stable daily variation. All parameters of leukocytes and thrombocytes were significantly reduced as storage time passed (P<0.01 or 0.001), except for lymphocytes (P=0.535). However, no significant differences were observed in parameters of erythrocytes from blood up to 120 hours. From above results, we assert that Hemavet 950FS is useful in analyzing CBC, except for MO, EO, and BA. For accurate detection of leukocyte and thrombocyte parameters, analysis should be performed within 4 hours after blood collection when using Hemavet 950FS. On the other hand, parameters of erythrocytes could be stably detected for at least 120 hours after blood collection.

Blood Analysis for Indirect Doping Control of Erythropoietin in Sports (운동선수들의 혈액분석을 통한 Etrythropoietin 간접도핑검사)

  • 이정란;김소영;홍지연;김명수;최명자
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    • v.47 no.6
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    • pp.422-431
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    • 2003
  • The use of recombinant human erythropoietin (rhEPO), a stimulator of erythropoiesis, banned in sports because of the medical risk associated with thrombosis. Due to analytical difficulties to differentiate between natural human EPO (hEPO) and rhEPO, blood parameters of erythropoiesis such as contents of hemoglobin (cut-off value <17.5 g/d l for man, and < 16.0 g/dl for women), hematocrit and reticulocytes (cut-off value <2.0%) were measured to focus the misuse of rhEPO. We conducted anti-doping test for 122 blood samples of the World Cup athletes. The mean values of key parameters are as follows; 14.5$\pm$1.0 g/dl for hemoglobin, 41.7$\pm$2.8% for hematocrit, and 1.3$\pm$0.4% for reticulocyte. Blood sample was found to be stable up to 8 hours for the reticulocyte measurement. In addition, the soluble transferrin receptor and ferritin levels were measured by immunoassay methods using plasma samples (n=28) in which the mean value was 0.8$\pm$0.5 $\mu\textrm{g}$/$m\ell$ and 54.6$\pm$33.7 ng/$m\ell$, respectively. The results indicate that all samples tested were negative for the blood parameters of indirect anti-doping test for hEPO misuse. The statistical evaluation suggest that several other parameters such as red blood cell, mean corpuscular hemoglobin concentration, mean corpuscular volume, mean corpuscular hemoglobin and white blood cell could be considered as factors influencing hEPO function in addition to five parameters mentioned.

An estimating method for systolic blood pressure by using pulse transit time and physical characteristic parameters (맥파전달시간과 신체특징 파라미터를 이용한 수축기 혈압측정)

  • Lee Sangmin;Park Eun Kyung;Kim In Young;Kim Sun I.
    • Journal of the Institute of Electronics Engineers of Korea SC
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    • v.42 no.3
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    • pp.41-46
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    • 2005
  • In this paper, we proposed noninvasive and continous measurement of blood pressure using pulse transit time(PTT) and physical characteristic parameters and verified its clinical effectiveness. PTT can be obtained by electrocardiogram and phtoplethysmogram. There are many researches for estimating blood pressure using PTT which can be used for individual. However, it is not enough for extracting general regression equation which can estimate blood pressure for unspecified people. In this study, we suggested the regression equatin using PTT and physical characteristic parameters related to blood pressure and did measure blood pressure of many people. we compared the performance between two methods. As the results, we knew that the regressin model using PTT combined with physical characteristic parameters can estimate blood pressure more acurately and is closer to American National Standards Institute of the Association of the Advancement of Medical Instrument(ANSI/AAMI).

Measurement and Analysis of Rodent Biological Signals using Telemetry System (원격측정장치를 이용한 설치류의 생체신호 측정 및 분석)

  • Kim, Chang-Hwan;Hur, Gyeong-Haeng
    • Journal of the Korea Institute of Military Science and Technology
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    • v.14 no.6
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    • pp.1159-1165
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    • 2011
  • Telemetry techniques of rats have been used for assessing safety pharmacology of drugs and chemicals. Biological signals including blood pressure and heart rate measured under anesthesia were significantly different from those obtained under normal conditions. The stress of restraint in awake animals can also affect the accuracy of physiological evaluation. This paper details the surgery required to allow key cardiovascular parameters to be determined. The telemetric measurement of cardiovascular parameters such as blood pressure, heart rate, electrocardiograph(ECG) established. We carried out the continuous monitoring of cardiovascular parameters using the telemetry system in F344 rats. During the measurement, no significant changes were observed in the heart rate and blood pressure. ECG signals and body temperature were also constant during the measurement of biological signals. With the results of this study, we conclude that this telemetry system can be applied usefully for the assesment of biological parameters in the rats.

Correlation of Serum Antioxidant Minerals with Blood Lipid Parameters in Obese Middle School Students

  • Kim, Mi-Hyun;Lee, Da-Hong;Sung, Chung-Ja
    • Preventive Nutrition and Food Science
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    • v.12 no.1
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    • pp.23-28
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    • 2007
  • The purpose of this study was to investigate the relationships of obesity, serum antioxidant mineral concentrations and blood lipid parameters in middle school students. Subjects were assigned to two groups, obese (BMI$\geq$25, 32 boys, 24 girls) and normal group (18.5

Evaluation of clinical usefulness of reference interval of some selected hematological parameters in canine blood

  • Pak, Son-Il;Han, Ho-Jae
    • Korean Journal of Veterinary Research
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    • v.44 no.4
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    • pp.649-653
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    • 2004
  • To estimate the source of variance components for some hematological parameters and assess the utility of the conventional population-based reference interval, this study computed index of individuality for blood samples, which were from 13 dogs drawn once weekly for 4 consecutive weeks. Results were subjected to nested analysis of variance. For all parameters measured between-dog variations were greater than within-dog variation. Except for the parameters RBC and MCHC the index of individuality was <1.4. The low reliability coefficient and high index of individuality of ${\leq}0.8$ were found for the majority of hematological parameters. In practical term, the present study indicated that use of hemogram profiles alone in the evaluating clinical state of a single patient should be avoided because of their physiological or natural random variations, and that comparing a single measurement on the blood analytes from an individual dog to the conventional population-based reference range may be too insensitive to detect any significant changes in the blood components of that particular dog. A single measurement may not characterize an individual's average concentration of the parameters even shortterm period.